Pratima Sharma
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View article: Isolation, Quantification, and Analysis of Isoflavones in Various Soybean Varieties and Their Health Implications
Isolation, Quantification, and Analysis of Isoflavones in Various Soybean Varieties and Their Health Implications Open
The soybean (Glycine Max) is a globally important crop, valued for its high protein, oil, and isoflavone content. Isoflavones, a class of phytoestrogens found predominantly in soybeans, have been associated with various health benefits, in…
View article: Predictors of response to terlipressin therapy in hepatorenal syndrome: Metabolomic and proteomic analysis from the CONFIRM trial
Predictors of response to terlipressin therapy in hepatorenal syndrome: Metabolomic and proteomic analysis from the CONFIRM trial Open
Background: Terlipressin is the only FDA-approved vasoconstrictor for hepatorenal syndrome (HRS). The CONFIRM study is the largest trial of terlipressin versus placebo. Novel predictors of HRS response are required to enrich patient select…
View article: Effect of Chemotherapy on Protein Level of Under Treatment Cancer Sufferers
Effect of Chemotherapy on Protein Level of Under Treatment Cancer Sufferers Open
Introduction: Cancer staging is an important aspect of cancer management and directly affects the treatment plan of the patient. There are several protein tumour markers that helps in the diagnosis as well as prognosis of cancer patients. …
View article: Correlation between antenatal and postnatal coiling index and its role in prediction of perinatal outcome: A prospective cohort study
Correlation between antenatal and postnatal coiling index and its role in prediction of perinatal outcome: A prospective cohort study Open
Background: The umbilical cord has pivotal role in the development, well-being, and survival of fetus and is vulnerable to kinking, torsion, and compression affecting perinatal outcome adversely. Aims and Objectives: This study was aimed t…
View article: Association of Hepatorenal Syndrome-Acute Kidney Injury with Mortality in Patients with Cirrhosis Requiring Renal Replacement Therapy
Association of Hepatorenal Syndrome-Acute Kidney Injury with Mortality in Patients with Cirrhosis Requiring Renal Replacement Therapy Open
Key Points In patients with cirrhosis and AKI requiring renal replacement therapy (RRT), hepatorenal syndrome-AKI was not associated with an increased 90-day mortality when compared with other AKI etiologies. Etiology of AKI may not be a c…
View article: Comparative study on the efficacy of mifepristone versus mifepristone and misoprostol in the induction of labor in cases of intrauterine fetal demise
Comparative study on the efficacy of mifepristone versus mifepristone and misoprostol in the induction of labor in cases of intrauterine fetal demise Open
Background: This study aimed to compare the efficacy of two labor induction methods, mifepristone alone and mifepristone followed by misoprostol, in cases of intrauterine fetal demise (IUFD) beyond 28 weeks of gestation. Methods: A prospec…
View article: Association of vaccination status with the clinicobiochemical profile, hospital stay, and mortality in COVID‐19: A case–control study
Association of vaccination status with the clinicobiochemical profile, hospital stay, and mortality in COVID‐19: A case–control study Open
Background and Aims The effectiveness of coronavirus disease 2019 (COVID‐19) vaccines in reducing symptoms, disease advancement, complications, and mortality in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection has bee…
View article: Extracorporeal Immunomodulation Therapy in Acute Chronic Liver Failure With Multiorgan Failure: First in Human Use
Extracorporeal Immunomodulation Therapy in Acute Chronic Liver Failure With Multiorgan Failure: First in Human Use Open
Two patients presented with acute on chronic liver failure and multiorgan failure and, as typical for this disorder, they presented with hyperinflammation and anticipated high mortality rates. Both cases were diagnosed with hepatorenal syn…
View article: Incidence and outcomes of acute kidney injury including hepatorenal syndrome in hospitalized patients with cirrhosis in the US
Incidence and outcomes of acute kidney injury including hepatorenal syndrome in hospitalized patients with cirrhosis in the US Open
View article: Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19
Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19 Open
Background We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized …
View article: Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium
Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium Open
Background. Length of stay (LOS) during index solid organ transplant impacts morbidity and healthcare costs. To date, there are no studies evaluating characteristics and outcomes of simultaneous liver-kidney transplant (SLKT) index hospita…
View article: Factors associated with cardiovascular events after simultaneous liver–kidney transplant from the US Multicenter Simultaneous Liver–Kidney Transplant Consortium
Factors associated with cardiovascular events after simultaneous liver–kidney transplant from the US Multicenter Simultaneous Liver–Kidney Transplant Consortium Open
Cardiovascular disease is a leading complication after both liver and kidney transplantation. Factors associated with and rates of cardiovascular events (CVEs) after simultaneous liver–kidney transplant (SLKT) are unknown. This was a retro…
View article: Delayed identification of massive pituitary apoplexy in pregnancy: A case report
Delayed identification of massive pituitary apoplexy in pregnancy: A case report Open
View article: Assessment of donor quality and risk of graft failure after liver transplantation: The ID2EAL score
Assessment of donor quality and risk of graft failure after liver transplantation: The ID2EAL score Open
View article: Burden of early hospitalization after simultaneous liver–kidney transplantation: Results from the US Multicenter SLKT Consortium
Burden of early hospitalization after simultaneous liver–kidney transplantation: Results from the US Multicenter SLKT Consortium Open
The burden of early hospitalization (within 6 months) following simultaneous liver–kidney transplant (SLKT) is not known. We examined risk factors associated with early hospitalization after SLKT and their impact on patient mortality condi…
View article: Hearts of Steel
Hearts of Steel Open
View article: Impact of medical eligibility criteria and OPTN policy on simultaneous liver kidney allocation and utilization
Impact of medical eligibility criteria and OPTN policy on simultaneous liver kidney allocation and utilization Open
Background Organ Procurement and Transplantation Network (OPTN) implemented medical eligibility and safety‐net policy on 8/10/17 to optimize simultaneous liver‐kidney (SLK) utilization. We examined impact of this policy on SLK listings and…
View article: CAQ Corner: Evolution of liver allocation policy
CAQ Corner: Evolution of liver allocation policy Open
Peer Reviewed
View article: Intraoperative risk factors of acute kidney injury following liver transplantation
Intraoperative risk factors of acute kidney injury following liver transplantation Open
Peer Reviewed
View article: Introducing the Certificate of Added Qualification (CAQ) Corner
Introducing the Certificate of Added Qualification (CAQ) Corner Open
Peer Reviewed
View article: Management of cardiac diseases in liver transplant recipients: Comprehensive review and multidisciplinary practice-based recommendations
Management of cardiac diseases in liver transplant recipients: Comprehensive review and multidisciplinary practice-based recommendations Open
View article: The Utility of Noninvasive PET/CT Myocardial Perfusion Imaging in Adult Liver Transplant Candidates
The Utility of Noninvasive PET/CT Myocardial Perfusion Imaging in Adult Liver Transplant Candidates Open
Background. The optimal cardiovascular (CV) risk stratification in liver transplant (LT) candidates remains unclear. The aim of this study was to evaluate concordance of findings between dobutamine stress echocardiography (DSE), positron e…
View article: The Risk Factors of Cerebral Palsy among the Children Attending a Children’s Hospital
The Risk Factors of Cerebral Palsy among the Children Attending a Children’s Hospital Open
Background: Cerebral Palsy is a disorder of movement and posture caused by nonprogressive abnormal brain function. It is a lifelong condition and one of the most common causes of physical disability in children. The objective of this study…
View article: Coagulopathy and hemostasis management in patients undergoing liver transplantation
Coagulopathy and hemostasis management in patients undergoing liver transplantation Open
Patients with acute and chronic liver disease present with a wide range of disease states and severity that may require liver transplantation (LT). Physiologic alterations occur that are dynamic throughout all phases of perioperative care,…
View article: Intraoperative risk factors of acute kidney injury after liver transplantation
Intraoperative risk factors of acute kidney injury after liver transplantation Open
Acute kidney injury (AKI) is one of the most common complications of liver transplantation (LT). We examined the impact of intraoperative management on risk for AKI following LT. In this retrospective observational study, we linked data fr…
View article: Variation in COVID-19 disease severity at hospital admission over time and across hospitals
Variation in COVID-19 disease severity at hospital admission over time and across hospitals Open
During the spring 2020 COVID-19 surge, hospitals in Southeast Michigan were overwhelmed, and hospital beds were limited. However, it is unknown whether threshold for hospital admission varied across hospitals or over time. Using a statewid…
View article: Temporal Trends and Evolving Outcomes After Simultaneous Liver‐Kidney Transplantation: Results from the US SLKT Consortium
Temporal Trends and Evolving Outcomes After Simultaneous Liver‐Kidney Transplantation: Results from the US SLKT Consortium Open
We aimed to understand the contemporary changes in the characteristics and the determinants of outcomes among simultaneous liver‐kidney transplantation (SLKT) recipients at 6 liver transplantation centers in the United States. We retrospec…
View article: Simultaneous Liver‐Kidney Transplantation Following Standardized Medical Eligibility Criteria and Creation of the Safety Net: Less Appears to Be More
Simultaneous Liver‐Kidney Transplantation Following Standardized Medical Eligibility Criteria and Creation of the Safety Net: Less Appears to Be More Open
Peer Reviewed
View article: Equitable Access to Liver Transplant: Bridging the Gaps in the Social Determinants of Health
Equitable Access to Liver Transplant: Bridging the Gaps in the Social Determinants of Health Open
The COVID‐19 pandemic and social justice movement have highlighted the impact of social determinants of health (SDOH) and structural racism in the United States on both access to care and patient outcomes. With the evaluation for liver tra…
View article: Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome
Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome Open
In this trial involving adults with cirrhosis and HRS-1, terlipressin was more effective than placebo in improving renal function but was associated with serious adverse events, including respiratory failure. (Funded by Mallinckrodt Pharma…