Preena Bhalla
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View article: HIV-TB Cross-referral and Collaborative Strategy: 8 Years of Our Experience from An Urban Health Centre in North India
HIV-TB Cross-referral and Collaborative Strategy: 8 Years of Our Experience from An Urban Health Centre in North India Open
Our study highlights the strong need to scale up the integration and partnership between HIV and TB programmes for better and integrated diagnosis and care of HIV-TB co-infected patients.
View article: Study of gonococcal and chlamydial urethritis: Old culprits with a new story
Study of gonococcal and chlamydial urethritis: Old culprits with a new story Open
Introduction: Neisseria gonorrhoeae and Chlamydia trachomatis are the primary pathogens causing urethritis. A cross-sectional study was carried out in the Department of Microbiology in conjunction with the Department of Dermatology and STD…
View article: Epidemiological profile of candidiasis in HIV/AIDS patients in a tertiary care hospital
Epidemiological profile of candidiasis in HIV/AIDS patients in a tertiary care hospital Open
Background: Clinical research in fungal infections is largely a neglected area in health care settings in India. Candida species cause diseases ranging from mucosal infections to systemic mycoses depending on host’s immune status. Aim of t…
View article: Throat Carriage of Staphylococcus aureus
Throat Carriage of Staphylococcus aureus Open
Staphylococcus aureus is colonized in anterior nares, throat, axilla, groin, pharynx and gastrointestinal tract and damaged skin surface. Colonization provides a reservoir from which bacteria can be introduced in the body in immunocompromi…
View article: Clinico-mycological analysis and antifungal resistance pattern in human immunodeficiency virus-associated candidiasis: An Indian perspective
Clinico-mycological analysis and antifungal resistance pattern in human immunodeficiency virus-associated candidiasis: An Indian perspective Open
Although C. albicans continues to be the leading etiological agent of candidiasis, the incidence of nonalbicans species among HIV-positive Indian individuals is rising. Antifungal resistance was higher among nonalbicans Candida…
View article: Correlation between venereal diseases research laboratory titers and CD4 T-lymphocyte count determined by flow cytometry in HIV-infected adults: A 5-year study
Correlation between venereal diseases research laboratory titers and CD4 T-lymphocyte count determined by flow cytometry in HIV-infected adults: A 5-year study Open
Although the correlation coefficient shows a positive correlation, the association was very weak. Therefore, CD4 cell count cannot be expected to influence VDRL titers in HIV-positive adults significantly.
View article: Herpetic perforation of prepuce
Herpetic perforation of prepuce Open
View article: Utility of a serum Aspergillusgalactomannan assay in diagnosis of invasive pulmonary Aspergillosis in HIV/AIDS patients: a prospective analysis
Utility of a serum Aspergillusgalactomannan assay in diagnosis of invasive pulmonary Aspergillosis in HIV/AIDS patients: a prospective analysis Open
Background: Invasive pulmonary aspergillosis (IPA) is a life threatening infection among immunocompromised patients. A timely and precise diagnosis of this condition is often precluded by lack of sensitive and specific noninvasive diagnost…
View article: Prevalence and Characteristics of Hepatitis B Virus in HIV Infected Patients in North India
Prevalence and Characteristics of Hepatitis B Virus in HIV Infected Patients in North India Open
To study the epidemiology of HBV and HCV infection in HIV infected patients using various markers of HBV and HCV. 70 HIV positive ART naïve patients and 70 HIV negative controls were included in the study. Their samples were retrospectivel…
View article: Fungal Opportunistic Pneumonias in HIV/AIDS Patients: An Indian Tertiary Care Experience
Fungal Opportunistic Pneumonias in HIV/AIDS Patients: An Indian Tertiary Care Experience Open
Fungal opportunistic pneumonias are common in HIV reactive patients in Indian setting and warrant a prompt and accurate diagnostic evaluation in the form of a combination of microbiological, serological and histopathological techniques, fo…
View article: Utility of Laboratory Diagnosis for Confirmation of the Syndromic Case Management in Married Indian Women with Vaginal Discharge
Utility of Laboratory Diagnosis for Confirmation of the Syndromic Case Management in Married Indian Women with Vaginal Discharge Open
Our study highlights the possible lacunae in SCM. Large number of patients may be over-treated if only syndromic management is followed, with financial, medical and social implications. Thus we recommend, the treatment maybe initiated on t…
View article: Seroprevalence of syphilis by VDRL test and biological false positive reactions in different patient populations: Is it alarming? Our experience from a tertiary care center in India
Seroprevalence of syphilis by VDRL test and biological false positive reactions in different patient populations: Is it alarming? Our experience from a tertiary care center in India Open
Although the overall seroprevalence of syphilis is low; the frequency of occurrence of BFP reactions is quite alarming. Hence, treponemal test must be used for confirmation of VDRL reactive sera.
View article: A Comparative Analysis of Polymerase Chain Reaction and Direct Fluorescent Antibody Test for Diagnosis of Genital Herpes
A Comparative Analysis of Polymerase Chain Reaction and Direct Fluorescent Antibody Test for Diagnosis of Genital Herpes Open
Objective: To compare laboratory tests that can simultaneously detect and type herpes simplex virus (HSV) directly from the genital ulcer specimens in clinically suspected cases of genital herpes. Materials and Methods: A study was conduct…
View article: Elevated levels of vascular endothelial growth factor in adults with severe dengue infection
Elevated levels of vascular endothelial growth factor in adults with severe dengue infection Open
View article: Sexually transmitted infections and HIV in self reporting men who have sex with men: A two-year study from India
Sexually transmitted infections and HIV in self reporting men who have sex with men: A two-year study from India Open
View article: Evaluation of Baseline CD4 + T Cell Counts and ART Requirement in Newly Diagnosed HIV Seropositive Individuals in a Tertiary Care Hospital of Northern India
Evaluation of Baseline CD4 + T Cell Counts and ART Requirement in Newly Diagnosed HIV Seropositive Individuals in a Tertiary Care Hospital of Northern India Open
In the present study, about three-fourth of newly diagnosed HIV positive Indian patients required initiation of ART at registration. The relatively low baseline CD4+ T cell counts in this population highlights the need for timely baseline …
View article: Evaluation of SD BIOLINE Syphilis 3.0 for Rapid Diagnosis of Syphilis: Report from a Regional Sexually Transmitted Infection Reference Laboratory in North India
Evaluation of SD BIOLINE Syphilis 3.0 for Rapid Diagnosis of Syphilis: Report from a Regional Sexually Transmitted Infection Reference Laboratory in North India Open
Background: Serology is considered the mainstay of syphilis diagnosis. The limitations of the traditional serological methods and the advent and availability of novel immunochromatographic assays have led to the widespread application of r…
View article: Spectrum of Opportunistic Fungal Infections in HIV/AIDS Patients in Tertiary Care Hospital in India
Spectrum of Opportunistic Fungal Infections in HIV/AIDS Patients in Tertiary Care Hospital in India Open
HIV related opportunistic fungal infections (OFIs) continue to cause morbidity and mortality in HIV infected patients. The objective for this prospective study is to elucidate the prevalence and spectrum of common OFIs in HIV/AIDS patients…
View article: Co-Infections and Sero-Prevalence of HIV, Syphilis, Hepatitis B and C Infections in Sexually Transmitted Infections Clinic Attendees of Tertiary Care Hospital in North India.
Co-Infections and Sero-Prevalence of HIV, Syphilis, Hepatitis B and C Infections in Sexually Transmitted Infections Clinic Attendees of Tertiary Care Hospital in North India. Open
High prevalence of HIV, HBV, HCV and syphilis in STI clinic attendees mandate routine screening to detect co-infections and follow prompt therapy in order to minimize their sequelae.
View article: Role of type-specific herpes simplex virus-1 and 2 serology as a diagnostic modality in patients with clinically suspected genital herpes: A comparative study in Indian population from a tertiary care hospital
Role of type-specific herpes simplex virus-1 and 2 serology as a diagnostic modality in patients with clinically suspected genital herpes: A comparative study in Indian population from a tertiary care hospital Open
HSV-2 IgG detection helps in strengthening the diagnosis of recurrent HSV-2 disease, whereas the absence of HSV-2 IgG antibody helps in excluding genital herpes as a likely cause of recurrent genital ulceration. However, detection of HSV-1…
View article: Pneumocystis pneumonia in HIV patients: a diagnostic challenge till date
Pneumocystis pneumonia in HIV patients: a diagnostic challenge till date Open
HIV has become a major health problem in India, patients commonly succumb to opportunistic infections (OIs), respiratory infections being an important cause of morbidity and their accurate diagnosis is still a challenge. Our aim was to stu…
View article: Asymptomatic reproductive tract infections/sexually transmitted infections among HIV positive women
Asymptomatic reproductive tract infections/sexually transmitted infections among HIV positive women Open
This study aims to highlight the importance of screening all HIV positive women for various reproductive tract infections/sexually transmitted infections (RTIs/STIs) irrespective of symptoms and to determine its occurrence in asymptomatic …
View article: An Audit of VDRL Testing from an STI Clinic in India: Analysing the Present Scenario with Focus on Estimating and Optimizing the Turnaround Time
An Audit of VDRL Testing from an STI Clinic in India: Analysing the Present Scenario with Focus on Estimating and Optimizing the Turnaround Time Open
Our study highlights the strong need to shift to alternative testing methods, mainly rapid point of care procedures for serodiagnosis of syphilis in order to circumvent the problems of long turnaround time and low patient follow-up rates.
View article: Is Scrub Typhus a Cause of Febrile Illness Among Paediatric Population of Delhi?
Is Scrub Typhus a Cause of Febrile Illness Among Paediatric Population of Delhi? Open
Scrub typhus is a febrile illness caused by Orientia tsutsugamushi and transmitted through the bite of larval forms of trombiculid mites [1].The signs and symptoms of the disease are relatively nonspecific and in areas like Delhi where out…
View article: Rising trend of antimicrobial resistance among Neisseria gonorrhoeae isolates and the emergence of N. gonorrhoeae isolate with decreased susceptibility to ceftriaxone
Rising trend of antimicrobial resistance among Neisseria gonorrhoeae isolates and the emergence of N. gonorrhoeae isolate with decreased susceptibility to ceftriaxone Open
The results of our study highlighted an alarming increase in the percentage of PPNG and QRNG strains over the years. Emergence of N. gonorrhoeae isolates with decreased susceptibility to third-generation cephalosporins is a cause of concer…
View article: Prevalence of reproductive tract infections and their determinants in married women residing in an urban slum of North-East Delhi, India
Prevalence of reproductive tract infections and their determinants in married women residing in an urban slum of North-East Delhi, India Open
A high case load was found based on the syndromic approach. Generating community awareness, ensuring proper menstrual hygiene, and improving the socioeconomic status would help in reducing the cases of RTI.
View article: A study of HIV-concordant and -discordant couples attending voluntary counselling and testing services at a tertiary care center in North India
A study of HIV-concordant and -discordant couples attending voluntary counselling and testing services at a tertiary care center in North India Open
A large number of Indian couples are exposed to the risk of heterosexual human immunodeficiency virus (HIV) transmission. The present records-based study was undertaken at the voluntary counselling and testing facility of a tertiary care h…
View article: Chlamydial infection: A clinical and public health perspective
Chlamydial infection: A clinical and public health perspective Open
Chlamydial infection remains one of the most common bacterial infectious diseases in the world. Over 100 million urogenital infections due to Chlamydia trachomatis occur each year according to the World Health Organization. This book cover…