Pritha Roy
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View article: A155 STOOL-BASED PROTEIN SIGNATURES FOR NON-INVASIVE ACCURATE DIAGNOSIS AND SUBTYPING OF INFLAMMATORY BOWEL DISEASE THROUGH HIGH-THROUGHPUT PROTEOMICS AND MACHINE LEARNING APPROACHES
A155 STOOL-BASED PROTEIN SIGNATURES FOR NON-INVASIVE ACCURATE DIAGNOSIS AND SUBTYPING OF INFLAMMATORY BOWEL DISEASE THROUGH HIGH-THROUGHPUT PROTEOMICS AND MACHINE LEARNING APPROACHES Open
Background Accurate diagnosis of inflammatory bowel disease (IBD) is essential to distinguish it from other conditions with similar symptoms and to identify whether it’s ulcerative colitis (UC) or Crohn’s disease (CD), ensuring appropriate…
View article: Adjuvant Intensity Modulated Radiation Therapy With a Pedicled Flap Reconstruction in Oral Cavity Squamous Cell Carcinomas: Implications on Target Delineation
Adjuvant Intensity Modulated Radiation Therapy With a Pedicled Flap Reconstruction in Oral Cavity Squamous Cell Carcinomas: Implications on Target Delineation Open
Objectives To address controversies regarding target volume delineation for adjuvant intensity‐modulated radiation therapy for oral cavity squamous cell carcinoma with pedicled flap reconstruction and elective nodal irradiation (ENI). Mate…
View article: Authors’ reply to Reddy
Authors’ reply to Reddy Open
We sincerely appreciate the thoughtful comments made by Reddy[1] in his correspondence regarding our study, "The impact of pathological complete response on survival in patients with breast cancer and occurrence in different intrinsic subt…
View article: The impact of pathological complete response on survival in patients with breast cancer and occurrence in different intrinsic subtypes: A retrospective observational study
The impact of pathological complete response on survival in patients with breast cancer and occurrence in different intrinsic subtypes: A retrospective observational study Open
JOURNAL/crsat/04.03/02201859-202306020-00004/figure1/v/2023-08-03T140821Z/r/image-tiff Background: Pathological complete response (pCR), defined as non-invasive or in situ disease in the breast and regional lymph nodes following neoadjuvan…
View article: Incidence and clinical profile of brain metastasis treated with whole brain radiotherapy in a tertiary hospital in eastern India: A retrospective audit
Incidence and clinical profile of brain metastasis treated with whole brain radiotherapy in a tertiary hospital in eastern India: A retrospective audit Open
Introduction: Management of brain metastases (BM) is witnessing marked advancement worldwide and modern technologies with better outcomes are gradually being adopted in developing countries. However, data regarding current practice in this…
View article: Epidemiological challenges in pandemic coronavirus disease (<scp>COVID</scp>‐19): Role of artificial intelligence
Epidemiological challenges in pandemic coronavirus disease (<span>COVID</span>‐19): Role of artificial intelligence Open
World is now experiencing a major health calamity due to the coronavirus disease (COVID‐19) pandemic, caused by the severe acute respiratory syndrome coronavirus clade 2. The foremost challenge facing the scientific community is to explore…
View article: Efficacy of brief cognitive behavioural intervention for the treatment of psychosis: A case report
Efficacy of brief cognitive behavioural intervention for the treatment of psychosis: A case report Open
Cognitive behavioural therapy (CBT) has been found to have strong empirical evidence for the treatment of anxiety and mood disorders. However, its applicability to schizophrenia and other psychotic disorders have posed as a challenge to cl…
View article: Cytogenetic Abnormalities in Multiple Myeloma: Incidence, Prognostic Significance, and Geographic Heterogeneity in Indian and Western Populations
Cytogenetic Abnormalities in Multiple Myeloma: Incidence, Prognostic Significance, and Geographic Heterogeneity in Indian and Western Populations Open
Multiple myeloma (MM) is a genetically complex and heterogeneous neoplasm in which cytogenetics is a major factor playing an important role in the risk stratification of disease. High-risk MM based upon cytogenetic classification includes …
View article: Efficacy of chronomodulated chemotherapy for palliation of hematemesis in inoperable gastric cancer: A single-institutional retrospective study
Efficacy of chronomodulated chemotherapy for palliation of hematemesis in inoperable gastric cancer: A single-institutional retrospective study Open
PGC group was maximally benefited considering all three parameters. Though surgery defines the mainstay of treatment for gastric carcinoma, yet in inoperable cases, only chronomodulated chemotherapy significantly affects the severity of UG…
View article: Combined analysis of trabectome and phaco-trabectome outcomes by glaucoma severity
Combined analysis of trabectome and phaco-trabectome outcomes by glaucoma severity Open
Prior glaucoma severity staging systems were mostly concerned with visual field function and retinal nerve fiber layer, but did not include intraocular pressure or medications to capture resistance to treatment. We recently introduced a si…
View article: Steroid‐induced glaucoma treated with trabecular ablation in a matched comparison with primary open‐angle glaucoma
Steroid‐induced glaucoma treated with trabecular ablation in a matched comparison with primary open‐angle glaucoma Open
Background To evaluate the outcomes of trabectome‐mediated ab interno trabeculectomy in patients with steroid‐induced glaucoma (SIG). Design A retrospective, observational cohort study performed in the Department of Ophthalmology, Universi…
View article: Combined analysis of trabectome and phaco-trabectome outcomes by glaucoma severity
Combined analysis of trabectome and phaco-trabectome outcomes by glaucoma severity Open
Prior glaucoma severity staging systems were mostly concerned with visual field function and retinal nerve fiber layer, but did not include intraocular pressure or medications to capture resistance to treatment. We recently introduced a si…
View article: Combined analysis of trabectome and phaco-trabectome outcomes by glaucoma severity [version 1; referees: 2 approved]
Combined analysis of trabectome and phaco-trabectome outcomes by glaucoma severity [version 1; referees: 2 approved] Open
Prior glaucoma severity staging systems were mostly concerned with visual field function and retinal nerve fiber layer, but did not include intraocular pressure or medications to capture resistance to treatment. We recently introduced a si…
View article: Impact of a Glaucoma Severity Index on Results of Trabectome Surgery: Larger Pressure Reduction in More Severe Glaucoma
Impact of a Glaucoma Severity Index on Results of Trabectome Surgery: Larger Pressure Reduction in More Severe Glaucoma Open
A simple glaucoma index, GI, was created to capture glaucoma severity and a relative resistance to treatment. A higher GI was associated with a larger IOP reduction in trabectome surgery. This indicates that there is a role for AIT beyond …
View article: A Porcine Anterior Segment Perfusion and Transduction Model With Direct Visualization of the Trabecular Meshwork
A Porcine Anterior Segment Perfusion and Transduction Model With Direct Visualization of the Trabecular Meshwork Open
Compared with previously used human donor eyes, this inexpensive porcine anterior segment perfusion model is of sufficient, repeatable high quality to develop strategies of TM bioengineering. Trabecular meshwork could be observed directly.…
View article: Regionally Discrete Aqueous Humor Outflow Quantification Using Fluorescein Canalograms
Regionally Discrete Aqueous Humor Outflow Quantification Using Fluorescein Canalograms Open
An algorithm was developed that analyzes regional and circumferential outflow patterns. This algorithm found flow patterns that changed over time and differ in whole eyes and anterior segment cultures.
View article: Differential Canalograms Detect Outflow Changes from Trabecular Micro-Bypass Stents and Ab Interno Trabeculectomy
Differential Canalograms Detect Outflow Changes from Trabecular Micro-Bypass Stents and Ab Interno Trabeculectomy Open
The increasing prevalence of glaucoma, a leading cause of blindness, makes the development of safer and more effective treatment more urgent. Recently introduced microincisional glaucoma surgeries that enhance conventional outflow offer a …
View article: Gene Transfer to the Outflow Tract
Gene Transfer to the Outflow Tract Open
Elevated intraocular pressure is the primary cause of open angle glaucoma. Outflow resistance exists within the trabecular meshwork but also at the level of Schlemm′s canal and further downstream within the outflow system. Viral vectors al…
View article: Live outflow imaging in porcine eyes
Live outflow imaging in porcine eyes Open
Purpose:
Although outflow of aqueous humor can be estimated using fluorophotometry and tonography, no method exists to assess segmental outflow directly. This has hindered investigations into outflow resistance elements that are downstre…
View article: Stratification of phaco-trabectome surgery results using a glaucoma severity index
Stratification of phaco-trabectome surgery results using a glaucoma severity index Open
The outcomes of phacoemulsification combined with trabectome surgery was analyzed using a glaucoma severity index based on preoperative intraocular pressure (IOP), number of preoperative medications, and visual field damage. Despite a less…
View article: Impact of a glaucoma severity index on results of trabectome surgery: larger pressure reduction in more severe glaucoma
Impact of a glaucoma severity index on results of trabectome surgery: larger pressure reduction in more severe glaucoma Open
Purpose
To stratify outcomes of trabectome-mediated ab interno trabeculectomy (AIT) by glaucoma severity using a simple and clinically useful glaucoma index. Based on prior data of trabectome after failed trabeculectomy, we hypothesized t…