Lin Pu
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Author Swipe
View article: BisBINOL-Based Fluorescent Probes: Effect of Alkane Linkers and Chemo- and Enantioselective Recognition of Arginine
BisBINOL-Based Fluorescent Probes: Effect of Alkane Linkers and Chemo- and Enantioselective Recognition of Arginine Open
A series of bisBINOL-based fluorescent probes, which contain two BINOL units linked by an alkane chain of varying length, were synthesized and characterized. It was found that the chain length of the alkane linker has strong effect on the …
View article: Exploring the association between systemic lupus erythematosus and osteonecrosis by Mendelian randomization analysis
Exploring the association between systemic lupus erythematosus and osteonecrosis by Mendelian randomization analysis Open
Patients with systemic lupus erythematosus (SLE) have been shown to have a high risk of osteonecrosis, but the potential causal relationship between genetic susceptibility and risk of osteonecrosis is unclear. In this study, we used Mendel…
View article: Fluorous-Phase- and Chiral-Axis-Enhanced Fluorescent Sensitivity and Chemoselectivity for Cysteine Recognition
Fluorous-Phase- and Chiral-Axis-Enhanced Fluorescent Sensitivity and Chemoselectivity for Cysteine Recognition Open
Highly fluorinated naphthyl aldehyde 1 and binaphthyl aldehyde (R)-2 were designed and synthesized for fluorous-phase-based sensing. Greatly enhanced sensitivity and chemoselectivity in going from 1 to (R…
View article: Association between anion gap/calcium ratio and 30-day all-cause mortality in sepsis patients with diabetes mellitus
Association between anion gap/calcium ratio and 30-day all-cause mortality in sepsis patients with diabetes mellitus Open
We aimed to determine the association between anion gap-to-calcium ratio (ACR) and 30-day mortality in sepsis patients with diabetes mellitus (DM). Data for sepsis patients diagnosed with DM was extracted from Medical Information Mart for …
View article: Associations between Anion Gap-to-Calcium Ratio and Mortality in Sepsis Patients with Diabetes Mellitus: A Retrospective Cohort Study
Associations between Anion Gap-to-Calcium Ratio and Mortality in Sepsis Patients with Diabetes Mellitus: A Retrospective Cohort Study Open
We aimed to determine the association between anion gap-to-calcium ratio (ACR) and 30-day mortality in sepsis patients with diabetes mellitus (DM). Data for sepsis patients diagnosed with DM was extracted from Medical Information Mart for …
View article: Regioselective Substitution of BINOL
Regioselective Substitution of BINOL Open
1,1'-Bi-2-naphthol (BINOL) has been extensively used as the chirality source in the fields of molecular recognition, asymmetric synthesis, and materials science. The direct electrophilic substitution at the aromatic rings of the optically …
View article: Outcomes of Multiple Organ Dysfunction Syndrome in Patients with Acute and Acute-on-Chronic Liver Failure in China: A Single Center Retrospective Cohort Study
Outcomes of Multiple Organ Dysfunction Syndrome in Patients with Acute and Acute-on-Chronic Liver Failure in China: A Single Center Retrospective Cohort Study Open
Acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) pose significant threats to patient prognosis, often leading to multiple organ dysfunction syndrome (MODS), which is characterized by simultaneous dysfunction of two or mo…
View article: Near‐IR Fluorescent Recognition of Arginine: High Chemoselectivity and Enantioselectivity Promoted by La<sup>3+</sup>
Near‐IR Fluorescent Recognition of Arginine: High Chemoselectivity and Enantioselectivity Promoted by La<sup>3+</sup> Open
The first near IR fluorescent probe for the chemoselective and enantioselective recognition of arginine in aqueous solution is reported in this work. This probe, made of a 1,1’‐binaphthyl‐based chiral aldehyde unit and a rhodamine‐based ne…
View article: High-Flow Nasal Cannula Oxygen Therapy versus Non-Invasive Ventilation in AIDS Patients with Acute Respiratory Failure: A Randomized Controlled Trial
High-Flow Nasal Cannula Oxygen Therapy versus Non-Invasive Ventilation in AIDS Patients with Acute Respiratory Failure: A Randomized Controlled Trial Open
Background: Acute respiratory failure (ARF) remains the most common diagnosis for intensive care unit (ICU) admission in acquired immunodeficiency syndrome (AIDS) patients. Methods: We conducted a single-center, prospective, open-labeled, …
View article: Pulmonary Infections and Outcomes in AIDS Patients with Respiratory Failure: A 10-Year Retrospective Review
Pulmonary Infections and Outcomes in AIDS Patients with Respiratory Failure: A 10-Year Retrospective Review Open
Pneumocystis jirovecii pneumonia was the primary etiology for respiratory failure in AIDS patients admitted to the ICU. Respiratory failure remains a severe illness with high mortality, and ICU mortality was negatively associated wi…
View article: CCDC 2084201: Experimental Crystal Structure Determination
CCDC 2084201: Experimental Crystal Structure Determination Open
View article: CCDC 2084202: Experimental Crystal Structure Determination
CCDC 2084202: Experimental Crystal Structure Determination Open
View article: CCDC 2084200: Experimental Crystal Structure Determination
CCDC 2084200: Experimental Crystal Structure Determination Open
View article: Genome-Wide Identification, Primary Functional Characterization of the NHX Gene Family in Canavalia rosea, and Their Possible Roles for Adaptation to Tropical Coral Reefs
Genome-Wide Identification, Primary Functional Characterization of the NHX Gene Family in Canavalia rosea, and Their Possible Roles for Adaptation to Tropical Coral Reefs Open
Canavalia rosea, distributed in the coastal areas of tropical and subtropical regions, is an extremophile halophyte with good adaptability to high salinity/alkaline and drought tolerance. Plant sodium/hydrogen (Na+/H+) exchanger (NHX) gene…
View article: Two-step fitness selection for intra-host variations in SARS-CoV-2
Two-step fitness selection for intra-host variations in SARS-CoV-2 Open
View article: Case Report: Extracorporeal Membrane Oxygenation In Curing A Young Man Post-Operative of The Modified Fontan Operation
Case Report: Extracorporeal Membrane Oxygenation In Curing A Young Man Post-Operative of The Modified Fontan Operation Open
Background: The Fontan operation is the only treatment option to change the anatomy of the heart and help improve patients’ hemodynamics. After successful operation, patients typically recover the ability to engage in general physical acti…
View article: Comparative therapeutic efficacy of interferon alfa-2b and combination lopinavir/ritonavir plus interferon alfa-2b against SARS-CoV-2
Comparative therapeutic efficacy of interferon alfa-2b and combination lopinavir/ritonavir plus interferon alfa-2b against SARS-CoV-2 Open
Background The outbreak of coronavirus disease 2019 (COVID-19) posed an enormous threat to public health. The use of antiviral drugs in patients with this disease have triggered people’s attentions. Whether interferon alfa-2b or lopinavir/…
View article: Genome-wide identification and expression analysis of aquaporin family in Canavalia rosea and their roles in the adaptation to saline-alkaline soils and drought stress
Genome-wide identification and expression analysis of aquaporin family in Canavalia rosea and their roles in the adaptation to saline-alkaline soils and drought stress Open
View article: Genome-Wide Identification, Structure Characterization, Expression Pattern Profiling, and Substrate Specificity of the Metal Tolerance Protein Family in Canavalia rosea (Sw.) DC
Genome-Wide Identification, Structure Characterization, Expression Pattern Profiling, and Substrate Specificity of the Metal Tolerance Protein Family in Canavalia rosea (Sw.) DC Open
Plant metal tolerance proteins (MTPs) play key roles in heavy metal absorption and homeostasis in plants. By using genome-wide and phylogenetic approaches, the origin and diversification of MTPs from Canavalia rosea (Sw.) DC. was explored.…
View article: Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity
Distinct durability of IgM/IgG antibody responses in COVID-19 patients with differing severity Open
View article: Intra-host dynamic variations in SARS-CoV-2
Intra-host dynamic variations in SARS-CoV-2 Open
The mutations make uncertain to SARS-CoV-2 disease control and vaccine development. At population-level, single nucleotide polymorphism (SNPs) have displayed mutations for illustrating epidemiology, transmission, and pathogenesis of COVID-…
View article: Bacterial and fungal co-infections among COVID-19 patients in intensive care unit
Bacterial and fungal co-infections among COVID-19 patients in intensive care unit Open
View article: Case Report: Identification of SARS-CoV-2 in Cerebrospinal Fluid by Ultrahigh-Depth Sequencing in a Patient With Coronavirus Disease 2019 and Neurological Dysfunction
Case Report: Identification of SARS-CoV-2 in Cerebrospinal Fluid by Ultrahigh-Depth Sequencing in a Patient With Coronavirus Disease 2019 and Neurological Dysfunction Open
We reported that the complete genome sequence of SARS-Coronavirus-2 (SARS-CoV-2) was obtained from a cerebrospinal fluid (CSF) sample by ultrahigh-depth sequencing. Fourteen days after onset, seizures, maxillofacial convulsions, intractabl…
View article: Yindan Jiedu Granules, a Traditional Chinese Medicinal Formulation, as a Potential Treatment for Coronavirus Disease 2019
Yindan Jiedu Granules, a Traditional Chinese Medicinal Formulation, as a Potential Treatment for Coronavirus Disease 2019 Open
Background: Yindan Jiedu Granules (YDJDG) have been newly prescribed as a Chinese herbal formula. This study aimed to compare the efficacy of YDJDG and lopinavir-ritonavir in the treatment of coronavirus disease 2019 (COVID-19). Methods: O…
View article: Investigation of Aquaporins Involved in the Adaptation of Canavalia Rosea to Saline-alkaline Soils and Drought Stress
Investigation of Aquaporins Involved in the Adaptation of Canavalia Rosea to Saline-alkaline Soils and Drought Stress Open
Background: Canavalia rosea (Sw.) DC. (bay bean) is an extremophile halophyte that is widely distributed in coastal areas of the tropics and subtropics. Seawater and drought tolerance in this species may be facilitated by aquaporins (AQPs)…
View article: Clinical Course and Risk Factors for Liver Injury of Severe and Critical Patients With COVID-19
Clinical Course and Risk Factors for Liver Injury of Severe and Critical Patients With COVID-19 Open
Background: Information regarding the clinical course of COVID-19 patients with liver injury is very limited, especially in severe and critical patients. The objective of this study was to describe the characteristics and clinical course o…
View article: Ectopic Expression of CrPIP2;3, a Plasma Membrane Intrinsic Protein Gene from the Halophyte Canavalia rosea, Enhances Drought and Salt-Alkali Stress Tolerance in Arabidopsis
Ectopic Expression of CrPIP2;3, a Plasma Membrane Intrinsic Protein Gene from the Halophyte Canavalia rosea, Enhances Drought and Salt-Alkali Stress Tolerance in Arabidopsis Open
Aquaporins are channel proteins that facilitate the transmembrane transport of water and other small neutral molecules, thereby playing vital roles in maintaining water and nutrition homeostasis in the life activities of all organisms. Can…
View article: CCDC 1999466: Experimental Crystal Structure Determination
CCDC 1999466: Experimental Crystal Structure Determination Open
View article: Differences and similarities of high-resolution computed tomography features between pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients
Differences and similarities of high-resolution computed tomography features between pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients Open
View article: Differences and similarities of high-resolution computed tomography features between pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients
Differences and similarities of high-resolution computed tomography features between pneumocystis pneumonia and cytomegalovirus pneumonia in AIDS patients Open
Background: Accurately differentiating pneumocystis from cytomegalovirus pneumonia is crucial for correct therapy selection in AIDS patients. Hence, the goal of this study was to compare the computerized tomography (CT ) features of pneumo…