Pura Bolaños
YOU?
Author Swipe
View article: Enteric Nervous System: Identification of a Novel Neuronal Sensory Network in the Duodenal Epithelium
Enteric Nervous System: Identification of a Novel Neuronal Sensory Network in the Duodenal Epithelium Open
The communication between the intestinal epithelium and the enteric nervous system has been considered indirect. Mechanical or chemical stimuli activate enteroendocrine cells inducing hormone secretion, which act on sub-epithelial nerve en…
View article: Excitation-contraction coupling in mammalian skeletal muscle: Blending old and last-decade research
Excitation-contraction coupling in mammalian skeletal muscle: Blending old and last-decade research Open
The excitation–contraction coupling (ECC) in skeletal muscle refers to the Ca 2+ -mediated link between the membrane excitation and the mechanical contraction. The initiation and propagation of an action potential through the membranous sy…
View article: Concomitant Antihyperalgesic and Antitumor Effects of Gabapentin in a Murine Cancer Pain Model
Concomitant Antihyperalgesic and Antitumor Effects of Gabapentin in a Murine Cancer Pain Model Open
Cancer pain may be the consequence of physical nerve compression by a growing tumor. We employed a murine model to study whether gabapentin was able to regulate tumor growth, in addition to controlling hyperalgesic symptoms. A fluorescent …
View article: The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms
The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms Open
Striated muscle contraction involves sliding of actin thin filaments along myosin thick filaments, controlled by calcium through thin filament activation. In relaxed muscle, the two heads of myosin interact with each other on the filament …
View article: Thick Filament Activation and Post-Tetanic Potentiation Mechanisms Evolved Differently in Invertebrate and Vertebrate Striated Muscle
Thick Filament Activation and Post-Tetanic Potentiation Mechanisms Evolved Differently in Invertebrate and Vertebrate Striated Muscle Open
View article: Cholesterol removal from adult skeletal muscle impairs excitation–contraction coupling and aging reduces caveolin-3 and alters the expression of other triadic proteins
Cholesterol removal from adult skeletal muscle impairs excitation–contraction coupling and aging reduces caveolin-3 and alters the expression of other triadic proteins Open
Cholesterol and caveolin are integral membrane components that modulate the function/location of many cellular proteins. Skeletal muscle fibers, which have unusually high cholesterol levels in transverse tubules, express the caveolin-3 iso…