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View article: Effect of NaCl on the structural properties, hydrolytic properties and binding of heptanal of oxidized myofibrillar proteins
Effect of NaCl on the structural properties, hydrolytic properties and binding of heptanal of oxidized myofibrillar proteins Open
This study investigated the effect of NaCl concentration on the structural properties, hydrolytic properties, and flavor binding capacity of oxidized myofibrillar proteins (MPs). The interaction mechanism of oxidized MPs hydrolyzed by tryp…
View article: Immune Checkpoint Inhibitor–Induced Ureteritis and Cystitis in Patients With Lung Cancer and Uterine Malignancies: A Case Series and Literature Review
Immune Checkpoint Inhibitor–Induced Ureteritis and Cystitis in Patients With Lung Cancer and Uterine Malignancies: A Case Series and Literature Review Open
Immune checkpoint inhibitors (ICIs) have demonstrated significant efficacy across various cancers but can cause immune-related adverse events (irAEs). While common irAEs such as dermatitis, pneumonitis, and colitis are well-documented, rar…
View article: Updated Review on Natural Polyphenols: Molecular Mechanisms, Biological Effects, and Clinical Applications for Cancer Management
Updated Review on Natural Polyphenols: Molecular Mechanisms, Biological Effects, and Clinical Applications for Cancer Management Open
Polyphenols, naturally occurring compounds found exclusively in plants, have gained significant attention for their potential in cancer prevention and treatment. These compounds are known for their antioxidant properties and are abundant i…
View article: Multimodal ultrasound: a non-invasive method for identifying dedifferentiation of papillary thyroid carcinoma during active surveillance
Multimodal ultrasound: a non-invasive method for identifying dedifferentiation of papillary thyroid carcinoma during active surveillance Open
Objectives To assess the diagnostic accuracy of multimodal ultrasound in differentiating anaplastic thyroid carcinoma (ATC) from papillary thyroid carcinoma (PTC) and to evaluate its capability in detecting thyroid carcinoma (TC) aggressiv…
View article: Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects
Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects Open
Cancer management has traditionally depended on chemotherapy as the mainstay of treatment; however, recent advancements in targeted therapies and immunotherapies have offered new options. Ubiquitin-specific proteases (USPs) have emerged as…
View article: FreqWave-TranDuD: A Multivariate Time Series Anomaly Detection Method Based on Wavelet and Fourier Transforms
FreqWave-TranDuD: A Multivariate Time Series Anomaly Detection Method Based on Wavelet and Fourier Transforms Open
Time series anomaly detection (AD) plays a crucial role in network systems. It enables the timely detection of anomalies and root cause analysis, helping to prevent unnecessary losses. Existing methods have not fully exploited the frequenc…
View article: Research progress of nursing interventions based on chronic illness trajectory framework for cancer patients
Research progress of nursing interventions based on chronic illness trajectory framework for cancer patients Open
Malignant tumors are a group of diseases that pose a serious threat to human health and life. In recent years, the morbidity and mortality rate have been on the rise, and their etiology, pathogenesis, clinical manifestations and treatment …
View article: Expression of Claudin-9 (CLDN9) in Breast Cancer, the Clinical Significance in Connection with Its Subcoat Anchorage Proteins ZO-1 and ZO-3 and Impact on Drug Resistance
Expression of Claudin-9 (CLDN9) in Breast Cancer, the Clinical Significance in Connection with Its Subcoat Anchorage Proteins ZO-1 and ZO-3 and Impact on Drug Resistance Open
(1) Introduction: Claudin-9 (CLDN9) is a member of the claudin protein family, a critical transmembrane protein family for tight junctions that are implemented in the progression of numerous cancer types. The present study investigated the…
View article: Performance Analysis and Optimal Design of HARQ-IR-Aided Terahertz Communications
Performance Analysis and Optimal Design of HARQ-IR-Aided Terahertz Communications Open
Terahertz (THz) communications are envisioned to be a promising technology for 6G thanks to its broad bandwidth. However, the large path loss, antenna misalignment, and atmospheric influence of THz communications severely deteriorate its r…
View article: Data from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells <i>In vitro</i> and <i>In vivo</i>
Data from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells <i>In vitro</i> and <i>In vivo</i> Open
Frequent genetic alterations of the components in the phosphoinositide 3-kinase (PI3K)/PTEN/AKT signaling pathway contribute greatly to breast cancer initiation and progression, which makes targeting this signaling pathway a promising ther…
View article: Data from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells <i>In vitro</i> and <i>In vivo</i>
Data from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells <i>In vitro</i> and <i>In vivo</i> Open
Frequent genetic alterations of the components in the phosphoinositide 3-kinase (PI3K)/PTEN/AKT signaling pathway contribute greatly to breast cancer initiation and progression, which makes targeting this signaling pathway a promising ther…
View article: Supplementary Figures 1-9 from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells <i>In vitro</i> and <i>In vivo</i>
Supplementary Figures 1-9 from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells <i>In vitro</i> and <i>In vivo</i> Open
Supplementary Figures 1-9 from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells In vitro and In vivo
View article: Supplementary Figures 1-9 from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells <i>In vitro</i> and <i>In vivo</i>
Supplementary Figures 1-9 from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells <i>In vitro</i> and <i>In vivo</i> Open
Supplementary Figures 1-9 from Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells In vitro and In vivo
View article: Activated Leukocyte Cell Adhesion Molecule (ALCAM), a Potential ‘Seed’ and ‘Soil’ Receptor in the Peritoneal Metastasis of Gastrointestinal Cancers
Activated Leukocyte Cell Adhesion Molecule (ALCAM), a Potential ‘Seed’ and ‘Soil’ Receptor in the Peritoneal Metastasis of Gastrointestinal Cancers Open
Activated Leukocyte Cell Adhesion Molecule (ALCAM/CD166) is a cell–cell adhesion protein conferring heterotypic and homotypic interactions between cells of the same type and different types. It is aberrantly expressed in various cancer typ…
View article: Striatins and STRIPAK complex partners in clinical outcomes of patients with breast cancer and responses to drug treatment
Striatins and STRIPAK complex partners in clinical outcomes of patients with breast cancer and responses to drug treatment Open
Our results suggest a possible role of the STRIPAK complex in breast cancer development and prognosis. Among the members, the expression profile of STRN3 presents a valuable factor for assessing patients' responses to drug treatment.
View article: Death associated protein‑3 (DAP3) and DAP3 binding cell death enhancer‑1 (DELE1) in human colorectal cancer, and their impacts on clinical outcome and chemoresistance
Death associated protein‑3 (DAP3) and DAP3 binding cell death enhancer‑1 (DELE1) in human colorectal cancer, and their impacts on clinical outcome and chemoresistance Open
Death associated protein‑3 (DAP3) was identified as a responsive protein to interferon‑gamma‑induced cell death which possibly exerts this regulation by interacting with DAP3 binding cell Death enhancer‑1 (DELE1), a newly discovered mitoch…
View article: Outage Performance Analysis of Type-I HARQ Aided V2V Communications
Outage Performance Analysis of Type-I HARQ Aided V2V Communications Open
Vehicle-to-vehicle (V2V) communications under dense urban environments usually experience severe keyhole fading effect, especially for multi-input multi-output (MIMO) channels, which degrades the capacity and outage performance due to the …
View article: Outage Probability Analysis of HARQ-Aided Terahertz Communications
Outage Probability Analysis of HARQ-Aided Terahertz Communications Open
Although terahertz (THz) communications can provide mobile broadband services, it usually has a large path loss and is vulnerable to antenna misalignment. This significantly degrades the reception reliability. To address this issue, the hy…
View article: Performance Analysis of MIMO-HARQ Assisted V2V Communications With Keyhole Effect
Performance Analysis of MIMO-HARQ Assisted V2V Communications With Keyhole Effect Open
Vehicle-to-vehicle (V2V) communications under dense urban environments usually experience severe keyhole fading effect especially for multi-input multi-output (MIMO) channels, which degrades the capacity and outage performance due to the r…
View article: Bioactive Molecules: Structures, Functions, and Potential Uses for Cancer Prevention and Targeted Therapies
Bioactive Molecules: Structures, Functions, and Potential Uses for Cancer Prevention and Targeted Therapies Open
Cancer continues to be an increasingly pervasive and destructive disease worldwide [...]
View article: Bilirubin inhibits the anticancer activity of sorafenib by blocking MCL-1 degradation in hepatocellular carcinoma cells
Bilirubin inhibits the anticancer activity of sorafenib by blocking MCL-1 degradation in hepatocellular carcinoma cells Open
Objective: Sorafenib is a first-line drug for advanced hepatocellular carcinoma (HCC). Unfortunately, most patients with HCC do not respond to sorafenib, mainly because of the frequent development of drug resistance. Bilirubin is an end me…
View article: Editorial: Unravelling Copper-Regulatory Systems and Copper-Affected Pathways in Cancer Cells to Improve Current Therapies
Editorial: Unravelling Copper-Regulatory Systems and Copper-Affected Pathways in Cancer Cells to Improve Current Therapies Open
EDITORIAL article Front. Mol. Biosci., 21 March 2022Sec. Cellular Biochemistry https://doi.org/10.3389/fmolb.2022.876902