Qingyun Liu
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View article: Strategies for Regulating Reactive Oxygen Species in Carbon Nitride-Based Photocatalysis
Strategies for Regulating Reactive Oxygen Species in Carbon Nitride-Based Photocatalysis Open
Reactive oxygen species (ROS) are increasingly recognized as decisive actors in photocatalytic redox chemistry, dictating both the selectivity and efficiency of target reactions, while most photocatalytic systems generate a mixture of ROS …
View article: Organoid models in oncology: advancing precision cancer therapy and vaccine development
Organoid models in oncology: advancing precision cancer therapy and vaccine development Open
Organoids are three-dimensional stem cell-derived models that offer a more physiologically relevant representation of tumor biology compared to traditional two-dimensional cell cultures or animal models. Organoids preserve the complex tiss…
View article: Enhancing diagnostic accuracy in rare and common fundus diseases with a knowledge-rich vision-language model
Enhancing diagnostic accuracy in rare and common fundus diseases with a knowledge-rich vision-language model Open
Previous foundation models for fundus images were pre-trained with limited disease categories and knowledge base. Here we introduce RetiZero, a vision-language model that incorporates knowledge from over 400 fundus diseases. The model is p…
View article: Cancer‐Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic Targets
Cancer‐Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic Targets Open
Cancer‐associated fibroblasts (CAFs) are functionally diverse stromal regulators that orchestrate tumor progression, metastasis, and therapy resistance through dynamic crosstalk within the tumor microenvironment (TME). Recent advances in s…
View article: Author response: Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer
Author response: Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer Open
View article: Non-Enzymatic Electrochemical Sensor for Accurately Detecting Norfloxacin Based on Porphyrin-Conjugated Microporous Polymers
Non-Enzymatic Electrochemical Sensor for Accurately Detecting Norfloxacin Based on Porphyrin-Conjugated Microporous Polymers Open
View article: Nonenzymatic Flexible Electrochemical Sensor For Levofloxacin Detecting Based on Bimetallic Sulfide Modified Porphyrin Composites
Nonenzymatic Flexible Electrochemical Sensor For Levofloxacin Detecting Based on Bimetallic Sulfide Modified Porphyrin Composites Open
View article: PEC biosensor with superior anti-interference and stability for homogeneous detection of ochratoxin A based on a separated-coupling electrolysis system
PEC biosensor with superior anti-interference and stability for homogeneous detection of ochratoxin A based on a separated-coupling electrolysis system Open
View article: A spatiotemporal comprehensive constraint interpolation method for missing values in monthly composite Suomi-NPP VIIRS Cloud Mask images
A spatiotemporal comprehensive constraint interpolation method for missing values in monthly composite Suomi-NPP VIIRS Cloud Mask images Open
The Earth’s nighttime light imaging data collected by the Visible Infrared Imaging Radiometer Suite Day/Night Band (VIIRS DNB) are severely lost in summer, hindering the further application of VIIRS DNB data. In this article, a spatiotempo…
View article: Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer
Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer Open
ZNRF3 and RNF43 are closely related transmembrane E3 ubiquitin ligases with significant roles in development and cancer. Conventionally, their biological functions have been associated with regulating WNT signaling receptor ubiquitination …
View article: Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer
Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer Open
ZNRF3 and RNF43 are closely related transmembrane E3 ubiquitin ligases with significant roles in development and cancer. Conventionally, their biological functions have been associated with regulating WNT signaling receptor ubiquitination …
View article: Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer
Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer Open
ZNRF3 and RNF43 are closely related transmembrane E3 ubiquitin ligases with significant roles in development and cancer. Conventionally, their biological functions have been associated with regulating WNT signaling receptor ubiquitination …
View article: Porphyrin Functionalized Montmorillonite Loaded Cu2o-Fe3o4 as a Sustainable Peroxidase Nanozyme for Colorimetric Determination of Hydroquinone
Porphyrin Functionalized Montmorillonite Loaded Cu2o-Fe3o4 as a Sustainable Peroxidase Nanozyme for Colorimetric Determination of Hydroquinone Open
View article: Fabricating of Pd and Ni Bimetal Modified Halloysite Nanotube Composite and its Application for Photocatalytic Degradation of Tetracycline
Fabricating of Pd and Ni Bimetal Modified Halloysite Nanotube Composite and its Application for Photocatalytic Degradation of Tetracycline Open
View article: Bias Voltage-Induced Structural Change in Pecvd-Deposited Diamond-Like Carbon Coatings for Optimizing the Tribological Performance
Bias Voltage-Induced Structural Change in Pecvd-Deposited Diamond-Like Carbon Coatings for Optimizing the Tribological Performance Open
View article: Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy
Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy Open
The treatment of diabetic wounds faces enormous challenges due to complex wound environments, such as infected biofilms, excessive inflammation, and impaired angiogenesis. The critical role of the microenvironment in the chronic diabetic w…
View article: Integrated Analysis of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Cold Tolerance in Litopenaeus vannamei
Integrated Analysis of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Cold Tolerance in Litopenaeus vannamei Open
DNA methylation is an important epigenetic modification that has been shown to be associated with responses to non-biological stressors. However, there is currently no research on DNA methylation in response to environmental signals in shr…
View article: Brincidofovir is a robust replication inhibitor against African swine fever virus <i>in vivo</i> and <i>in vitro</i>
Brincidofovir is a robust replication inhibitor against African swine fever virus <i>in vivo</i> and <i>in vitro</i> Open
African swine fever virus (ASFV) infection is a major public and socioeconomic concern that has a serious impact on the global swine industry. Unfortunately, there are currently no commercially available vaccines or antiviral agents that a…
View article: A Spatiotemporally Constrained Interpolation Method for Missing Pixel Values in the Suomi-NPP VIIRS Monthly Composite Images: Taking Shanghai as an Example
A Spatiotemporally Constrained Interpolation Method for Missing Pixel Values in the Suomi-NPP VIIRS Monthly Composite Images: Taking Shanghai as an Example Open
The Visible Infrared Imaging Radiometer Suite Day/Night Band (VIIRS/DNB) nighttime light data is a powerful remote sensing data source. However, due to stray light pollution, there is a lack of VIIRS data in mid-high latitudes during the s…
View article: Supplementary Figures S1-S7 from LGR5-Targeted Antibody–Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence
Supplementary Figures S1-S7 from LGR5-Targeted Antibody–Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence Open
Supplementary Fig. S1- Coomassie gel of anti-LGR5 mAb and anti-LGR5 ADCs. Supplementary Fig. S2- Confocal image of HEK293T cells with stable over-expression of hLGR4. Supplementary Fig. S3- Anti-LGR5 ADC binding assay and cytotoxicity of f…
View article: Data from LGR5-Targeted Antibody–Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence
Data from LGR5-Targeted Antibody–Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence Open
Gastrointestinal cancer is one of the leading causes of cancer-related mortality in men and women worldwide. The adult stem cell marker LGR5 (leucine-rich repeat-containing, G protein–coupled receptor 5) is highly expressed in a significan…
View article: Supplementary Figures S1-S7 from LGR5-Targeted Antibody–Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence
Supplementary Figures S1-S7 from LGR5-Targeted Antibody–Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence Open
Supplementary Fig. S1- Coomassie gel of anti-LGR5 mAb and anti-LGR5 ADCs. Supplementary Fig. S2- Confocal image of HEK293T cells with stable over-expression of hLGR4. Supplementary Fig. S3- Anti-LGR5 ADC binding assay and cytotoxicity of f…
View article: Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis Open
Mass spectrometry identifying EGFR-binding proteins
View article: Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis Open
Leucine-rich repeat-containing G protein–coupled receptors 4, 5, and 6 (LGR4/5/6) play critical roles in development and cancer. The widely accepted mechanism is that these proteins, together with their R-spondin ligands, stabilize Wnt rec…
View article: Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis Open
Leucine-rich repeat-containing G protein–coupled receptors 4, 5, and 6 (LGR4/5/6) play critical roles in development and cancer. The widely accepted mechanism is that these proteins, together with their R-spondin ligands, stabilize Wnt rec…
View article: Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis Open
Mass spectrometry identifying EGFR-binding proteins
View article: Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis Open
Supplementary figures 1-8
View article: Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis Open
Fullmoon antibody array and TCGA dataset analyses
View article: Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis Open
Supplementary figures 1-8
View article: Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis
Supplementary Data from A Wnt-Independent LGR4–EGFR Signaling Axis in Cancer Metastasis Open
Fullmoon antibody array and TCGA dataset analyses