Qamar Uddin Ahmed
YOU?
Author Swipe
View article: Flavonoids as Antidiabetic Agents, Challenges and Future Directions
Flavonoids as Antidiabetic Agents, Challenges and Future Directions Open
Diabetes is a global health concern, affecting hundreds of millions of people worldwide. The number of adults living with diabetes has risen dramatically, from approximately 200 million in 1990 to nearly 589 million in 2024. Type 2 diabete…
View article: THE ANTIPARASITIC POTENTIAL OF FLAVONOLS: A SYSTEMATIC REVIEW
THE ANTIPARASITIC POTENTIAL OF FLAVONOLS: A SYSTEMATIC REVIEW Open
Background: Parasites pose a significant global health hazard, especially in countries endowed with tropical climates. Despite the availability of different types of antiparasitic drugs, their harmful side effects and limited treatment opt…
View article: Red Seaweeds as Resource of Bioactive Compounds and Therapeutic Potential: a Review on Anticancer Agents
Red Seaweeds as Resource of Bioactive Compounds and Therapeutic Potential: a Review on Anticancer Agents Open
The use of natural compounds derived from macroalgae constitute an alternating strategy in the creation of anticancer medications. Seaweed refers to macroalgae. Red seaweeds are rich in bioactive compounds, including alkaloids, carotenoids…
View article: Antidiabetic potential of Phaleria macrocarpa fruit liquid CO₂ extract: Bioactivity, cytotoxicity, phytochemicals and molecular targets
Antidiabetic potential of Phaleria macrocarpa fruit liquid CO₂ extract: Bioactivity, cytotoxicity, phytochemicals and molecular targets Open
Type 2 diabetes is a chronic metabolic disorder marked by impaired insulin utilization and elevated blood glucose levels. Synthetic drugs often fall short in fully regulating glucose and can cause deleterious side effects during the treatm…
View article: A prospective study on the biodegradation of petroleum hydrocarbons mediated by selected marine bacterial isolates
A prospective study on the biodegradation of petroleum hydrocarbons mediated by selected marine bacterial isolates Open
View article: Comparative evaluation of phytochemical screening, in vitro antioxidant & α-Glucosidase inhibitory properties of <i>Ceiba pentandra</i> & <i>Basella rubra</i> leaf extracts: Identification of active principles by Q-TOFLCMS, ADMET prediction & molecular docking approach
Comparative evaluation of phytochemical screening, in vitro antioxidant & α-Glucosidase inhibitory properties of <i>Ceiba pentandra</i> & <i>Basella rubra</i> leaf extracts: Identification of active principles by Q-TOFLCMS, ADMET prediction & molecular docking approach Open
Ceiba pentandra and Basella rubra leaves are traditionally used in Indonesia to treat ailments like diabetes. This study aimed to validate their use by assessing their antioxidant and α-glucosidase inhibitory properties. Initially, macerat…
View article: Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent
Ethnopharmacology of Psychotria: Potential Use of P. malayana Jack Leaves as Antidiabetic Agent Open
This review provides a comprehensive exploration of the Psychotria species, a genus of plants known for their medicinal properties and traditional uses. The focus is on the species’ ethnomedicinal applications, their potential as an antidi…
View article: Antiseizure Medications: Advancements, Challenges, and Prospects in Drug Development
Antiseizure Medications: Advancements, Challenges, and Prospects in Drug Development Open
Epilepsy is a neurological disorder affecting millions of people worldwide. Antiseizure medications (ASM) remain a critical therapeutic intervention for treating epilepsy, notwithstanding the rapid development of other therapies. There hav…
View article: A review on multi-therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine: Experimental evidence and future perspectives
A review on multi-therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7-hydroxymitragynine: Experimental evidence and future perspectives Open
Mitragyna speciosa (kratom) is a traditional medicinal plant of Southeast Asia, known for its pharmacologically active alkaloids, mitragynine and 7-hydroxymitragynine. The chemistry, isolation, pharmacological properties, and toxicities of…
View article: Mitragyna speciosa Korth toxicity: Experimental findings and future prospects
Mitragyna speciosa Korth toxicity: Experimental findings and future prospects Open
Mitragyna speciosa (Roxb.) Korth, locally known as kratom, is a traditional medicinal plant from Southeast Asia, with mitragynine as its principal alkaloid. Similar to other medicinal plants, kratom has side effects and toxicities, …
View article: Green Guardians: the Role of Medicinal Plants in Combating Oxidative Stress
Green Guardians: the Role of Medicinal Plants in Combating Oxidative Stress Open
This chapter explores the collection of research articles that focus on the medicinal properties of various plants including Morinda citrifolia, Syzygium cumini, Ocimum sanctum, Murraya koenigii and Catharanthus roseus. This includes the d…
View article: Neurotoxicity of aluminium chloride and okadaic acid in zebrafish: Unravelling Alzheimer's disease model via learning and memory function evaluation
Neurotoxicity of aluminium chloride and okadaic acid in zebrafish: Unravelling Alzheimer's disease model via learning and memory function evaluation Open
Introduction/objectives: Alzheimer's disease (AD) is characterised by a progressive decline in cognitive abilities, especially learning and memory. To validate the zebrafish as a suitable model organism for AD, the study examined the effec…
View article: A review on <i>Mitragyna speciosa</i> (Rubiaceae) as a prominent medicinal plant based on ethnobotany, phytochemistry and pharmacological activities
A review on <i>Mitragyna speciosa</i> (Rubiaceae) as a prominent medicinal plant based on ethnobotany, phytochemistry and pharmacological activities Open
Mitragyna speciosa Korth (kratom) is a tropical indigenous tree of Southeast Asia. It is commonly consumed by the people due to its various pharmacological properties. The leaves of this plant are traditionally used for the treatmen…
View article: Identification of putative α-glucosidase inhibitors and antioxidants in <i>Zingiber officinale</i> rhizome using LCMS-based metabolomics and <i>in silico</i> molecular docking
Identification of putative α-glucosidase inhibitors and antioxidants in <i>Zingiber officinale</i> rhizome using LCMS-based metabolomics and <i>in silico</i> molecular docking Open
Metabolite profiling is required to reveal bioactive chemicals in ginger rhizome for supporting its traditional claim as anti-diabetic agent. This study aimed to evaluate α-glucosidase inhibitory (AGI) and antioxidant activities of the rhi…
View article: 5-Methylcoumarin-4β-glucoside mitigated colon tumor progression in mice with AOM/DSS-induced colon carcinogenesis
5-Methylcoumarin-4β-glucoside mitigated colon tumor progression in mice with AOM/DSS-induced colon carcinogenesis Open
Context: The in vitro cytotoxicity profile of 5-Methylcoumarin-4β-glucoside (5-MC4βG) has been demonstrated to inhibit the proliferation of HT-29 adenocarcinoma cells. Aim: The need for newer and affordable chemotherapeutic agents is criti…
View article: Mechanistic insights into the hepatoprotective properties of Mallotus phillipensis fruit: Targeting proinflammatory cytokines and free radicals using isolated compound
Mechanistic insights into the hepatoprotective properties of Mallotus phillipensis fruit: Targeting proinflammatory cytokines and free radicals using isolated compound Open
Ethnopharmacological relevance: Mallotus phillipensis (MP) belongs to the endangered plants of great medicinal value. Widely used in the Ayurvedic healthcare system, parts of the plant which are rich in secondary metabolites are used in th…
View article: Evaluation the role of Hydroalcoholic extract of Moringa Oleifera Lam Leaves in many Histological and Physiological parameters for male rats kidneys induced by Hyperlipidemia
Evaluation the role of Hydroalcoholic extract of Moringa Oleifera Lam Leaves in many Histological and Physiological parameters for male rats kidneys induced by Hyperlipidemia Open
View article: Zebrafish Housing: The Recirculating and Cost-effective Open Design Aquaria System
Zebrafish Housing: The Recirculating and Cost-effective Open Design Aquaria System Open
The zebrafish’s ease of care and high reproductive rate have made them a popular animal model. It is routinely kept and maintained in commercial aquariums. However, the expense of a particular system was prohibitive for researchers with li…
View article: High performance liquid chromatographic method optimized by Box-Behnken design model to determine caffeine in pharmaceutical preparations and urine samples
High performance liquid chromatographic method optimized by Box-Behnken design model to determine caffeine in pharmaceutical preparations and urine samples Open
View article: Morphological, teratogenic and behavioral evaluations of Gelidium spinosum methanol extract on zebrafish embryos
Morphological, teratogenic and behavioral evaluations of Gelidium spinosum methanol extract on zebrafish embryos Open
Gelidium spinosum is an edible red seaweed from the family Gelidiaceae with possibility to be developed. The potential medical benefits of G. spinosum have been established, yet adequate empirical research on its toxicity is still lacking.…
View article: A Prospective Study on the Biodegradation of Petroleum Hydrocarbons Mediated by Selected Marine Bacterial Isolates
A Prospective Study on the Biodegradation of Petroleum Hydrocarbons Mediated by Selected Marine Bacterial Isolates Open
View article: Wound Healing: Recent Advances in Etiology and Management, and the Therapeutic Potential of Natural Products
Wound Healing: Recent Advances in Etiology and Management, and the Therapeutic Potential of Natural Products Open
View article: In Vitro Anti-Diabetic, Anti-Inflammatory, Antioxidant Activities and Toxicological Study of Optimized Psychotria malayana Jack Leaves Extract
In Vitro Anti-Diabetic, Anti-Inflammatory, Antioxidant Activities and Toxicological Study of Optimized Psychotria malayana Jack Leaves Extract Open
Psychotria malayana Jack (Family: Rubiaceae, local name: Salung) is a traditional herb used to treat diabetes. A previous study by our research group demonstrated that P. malayana methanolic and water extract exhibits significant potential…
View article: The Presence of Whitefly Bemisia tabaci, and Thrips Thrips tabaci on Different Cucumber Plant Hybrid Varieties in the Field Conditions
The Presence of Whitefly Bemisia tabaci, and Thrips Thrips tabaci on Different Cucumber Plant Hybrid Varieties in the Field Conditions Open
The study was conducted to determine the susceptibility of different cucumber hybrid varieties (Jumbo Green, Ghazeer, Nefer, and Sahem) to sucking insect pests, onion thrips Thrips tabaci Lind., and tobacco whitefly Bemisia tabaci Genn., d…
View article: Antidiabetic activity evaluation of polyherbal formulation in type 2 diabetes mellitus patients
Antidiabetic activity evaluation of polyherbal formulation in type 2 diabetes mellitus patients Open
Objective: The main aim of this research was to evaluate the effect of mixed herbs on blood HbA1c, and the liver function tests in type 2 diabetes mellitus (T2DM) patients. Methods: This was a quasi-experimental design where no comparison …
View article: Phytochemical screening and in vitro evaluation of antioxidant and antimicrobial efficacies of Pteropyum scoparium (Jaub. & Spach) Sidaf crude extracts
Phytochemical screening and in vitro evaluation of antioxidant and antimicrobial efficacies of Pteropyum scoparium (Jaub. & Spach) Sidaf crude extracts Open
Objective:
\nPteropyrum scoparium Jaub. & Spach locally known as “Sidaf” is a meal known to the ancient Omani people with many health benefits. It is traditionally used in Oman to treat high cholesterol, hypertension, indigestion problems…
View article: Identification of cancer inhibitors from Hystrix brachyurabezoar extracts using LC-MS multivariate data analysis and in silico evaluation on Bcl-2, cyclin B/CDK1, VEGF and NM23-H1
Identification of cancer inhibitors from Hystrix brachyurabezoar extracts using LC-MS multivariate data analysis and in silico evaluation on Bcl-2, cyclin B/CDK1, VEGF and NM23-H1 Open
Hystrix brachyurabezoar is calcified undigested material found in the gastrointestinal tract known for various medicinal benefits including as an anticancer agent. However, the H. brachyurapopulation has been declining due to its demand an…
View article: Phytochemical analysis, antioxidant, α-glucosidase inhibitory activity, and toxicity evaluation of Orthosiphon stamineus leaf extract
Phytochemical analysis, antioxidant, α-glucosidase inhibitory activity, and toxicity evaluation of Orthosiphon stamineus leaf extract Open
Ocimum aristatum , commonly known as O. stamineus , has been widely studied for its potential as an herbal medicine candidate. This research aims to compare the efficacy of water and 100% ethanolic extracts of O. stamineus as α-glucosidase…
View article: Ethanolic Extract of Polygonum minus Protects Differentiated Human Neuroblastoma Cells (SH-SY5Y) against H2O2-Induced Oxidative Stress
Ethanolic Extract of Polygonum minus Protects Differentiated Human Neuroblastoma Cells (SH-SY5Y) against H2O2-Induced Oxidative Stress Open
Neuronal models are an important tool in neuroscientific research. Hydrogen peroxide (H2O2), a major risk factor of neuronal oxidative stress, initiates a cascade of neuronal cell death. Polygonum minus Huds, known as ‘kesum’, is widely us…
View article: Anti-obesity and antihyperlipidemic effects of Phaleria macrocarpa fruit liquid CO2 extract: In vitro, in silico and in vivo approaches
Anti-obesity and antihyperlipidemic effects of Phaleria macrocarpa fruit liquid CO2 extract: In vitro, in silico and in vivo approaches Open
Objective: Phaleria macrocarpa fruit has been reported to be effectively used in Malaysia and neighboring countries to prevent obesity. Despite its anti-obesity potential, no research has ever predicted the compound-lipase, compound-HMG-Co…