Qian Wang
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View article: Interaction between gut microbiota and immunity in health and intestinal disease
Interaction between gut microbiota and immunity in health and intestinal disease Open
The gut microbiota plays a fundamental role in establishing and maintaining host immune homeostasis through dynamic, bidirectional interactions with the innate and adaptive immune systems. This review synthesizes current knowledge on how c…
View article: Impact of Hydrosalpinx and Surgical Timing on Ovarian Reserve and Response in in vitro fertilization or intracytoplasmic sperm injection patients: A Retrospective Cohort Study with Propensity Score Analysis
Impact of Hydrosalpinx and Surgical Timing on Ovarian Reserve and Response in in vitro fertilization or intracytoplasmic sperm injection patients: A Retrospective Cohort Study with Propensity Score Analysis Open
Objective To investigate the impact of hydrosalpinx and the timing of surgical intervention on ovarian reserve and ovarian response in in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) patients. Design, setting, and p…
View article: AFB1 Promotes H3N8 Replication in Chickens by Impairing Gut Colonization of Protective Segmented Filamentous Bacteria
AFB1 Promotes H3N8 Replication in Chickens by Impairing Gut Colonization of Protective Segmented Filamentous Bacteria Open
AFB1, a common feed mycotoxin, can worsen viral infections. While H3N8 avian influenza mainly affects birds and can harm gut health, the combined impact of AFB1 and H3N8 infection on poultry intestines remains unknown. We show that environ…
View article: Research on Landscape Risks and Their Driving Mechanisms for Sustainable Development in Alpine Meadow Areas
Research on Landscape Risks and Their Driving Mechanisms for Sustainable Development in Alpine Meadow Areas Open
Landscape Ecological Risk Assessment (LERA) is the basis for stable ecological functions in alpine meadow areas and is closely related to sustainable development. The research of LERA is complex, and there are problems with its identificat…
View article: Structural and functional characterization of gut microbiota in dyslipidemic patients from high-altitude Tibetan pastoral areas
Structural and functional characterization of gut microbiota in dyslipidemic patients from high-altitude Tibetan pastoral areas Open
Introduction Approximately 49.3% of individuals living at high altitudes suffer from dyslipidemia. Emerging evidence indicates that gut microbiota can regulate lipid metabolism and cholesterol homeostasis, but the composition and function …
View article: Effect of acupuncture at force-sensitive acupoint on brain-gut peptides secretion in a model rats with functional dyspepsia
Effect of acupuncture at force-sensitive acupoint on brain-gut peptides secretion in a model rats with functional dyspepsia Open
View article: Paeoniflorin Attenuates Cognitive Dysfunction and Neuroinflammation by Autophagy in Mice with SLE Induced by Imiquimod
Paeoniflorin Attenuates Cognitive Dysfunction and Neuroinflammation by Autophagy in Mice with SLE Induced by Imiquimod Open
Paeoniflorin plays a critical neuroprotective role as demonstrated in the TLR-7 agonist imiquimod-induced murine lupus model, mediated through activation of autophagic flux via modulation of the PI3K/AKT/mTOR signaling axis.
View article: Multi-Scenario Simulation of the Impact of Landscape Patterns on Ecosystem Services in Alpine Meadow Regions
Multi-Scenario Simulation of the Impact of Landscape Patterns on Ecosystem Services in Alpine Meadow Regions Open
Aims The alpine meadow regions are mainly located in mountainous and plateau areas, exhibiting high sensitivity to climate change and human activities. Landscape pattern changes caused by human activities have a significant impact on ecosy…
View article: Enhanced tunnel construction safety: drill-and-blast construction tunnel deformation detection using LiDAR and cloth simulation filter
Enhanced tunnel construction safety: drill-and-blast construction tunnel deformation detection using LiDAR and cloth simulation filter Open
The drill-and-blast method remains the primary excavation technique for highway tunnels in mountainous regions, where the shotcrete lining plays a crucial role in the New Austrian Tunneling Method. However, due to blasting disturbances and…
View article: Correction: VNP20009-Abvec-Igκ-MIIP suppresses ovarian cancer progression by modulating Ras/MEK/ERK signaling pathway
Correction: VNP20009-Abvec-Igκ-MIIP suppresses ovarian cancer progression by modulating Ras/MEK/ERK signaling pathway Open
View article: Role of miR-101a in targeting Cox-2 to attenuate chondrocyte hypertrophic differentiation and osteoarthritis progression
Role of miR-101a in targeting Cox-2 to attenuate chondrocyte hypertrophic differentiation and osteoarthritis progression Open
View article: Role of echinacoside in alleviating depressive-like symptoms in chronic unpredictable mild stressed mice via PI3K/AKT/Nrf2/HO-1 signaling pathway
Role of echinacoside in alleviating depressive-like symptoms in chronic unpredictable mild stressed mice via PI3K/AKT/Nrf2/HO-1 signaling pathway Open
View article: Targeting the ubiquitin–proteasome system and drug therapy in colorectal cancer
Targeting the ubiquitin–proteasome system and drug therapy in colorectal cancer Open
Colorectal cancer (CRC) is the third most prevalent malignancy worldwide and the second leading cause of cancer-associated deaths, posing a significant threat to human health. Given the limited therapeutic options and poor prognosis associ…
View article: Advances in the prevention and management of postoperative bleeding complications in pancreaticoduodenectomy: Current strategies and future directions precise
Advances in the prevention and management of postoperative bleeding complications in pancreaticoduodenectomy: Current strategies and future directions precise Open
Postoperative bleeding (POB) is a major complication following pancreaticoduodenectomy (PD), leading to significant morbidity and potential mortality. This minireview focuses on the prevention and management strategies for POB, synthesizin…
View article: Inclusion of anti-vascular therapy as a promising option for later-line treatment of malignant pleural mesothelioma: a retrospective study
Inclusion of anti-vascular therapy as a promising option for later-line treatment of malignant pleural mesothelioma: a retrospective study Open
For patients with MPM requiring later-line treatment, the combination of chemotherapy and anti-vascular therapy may represent a viable therapeutic alternative, demonstrating an acceptable safety profile.
View article: Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy
Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy Open
Radiotherapy (RT) is a mainstay therapeutic strategy for cancer; however, increasing radiation damage to tumor tissues while reducing the side effects on healthy tissues remains a great challenge. To address this issue, the use of biomater…
View article: Effects of external diaphragm pacing combined with repetitive peripheral magnetic stimulation of the phrenic nerve on respiratory function in stroke patients
Effects of external diaphragm pacing combined with repetitive peripheral magnetic stimulation of the phrenic nerve on respiratory function in stroke patients Open
Objectives To investigate the effects of external diaphragmatic pacing (EDP) and repetitive peripheral magnetic stimulation (rPMS) of the phrenic nerve on respiratory function in stroke patients. Methods Fifty-four stroke patients were ran…
View article: [Efficacy and safety of venetoclax combined with tyrosine kinase inhibitors and reduced-dose chemotherapy in 13 cases of minimal residual disease-positive and relapsed/refractory Ph(+) acute lymphoblastic leukemia].
[Efficacy and safety of venetoclax combined with tyrosine kinase inhibitors and reduced-dose chemotherapy in 13 cases of minimal residual disease-positive and relapsed/refractory Ph(+) acute lymphoblastic leukemia]. Open
This study sought to evaluate the efficacy and safety of venetoclax (Ven) in combination with tyrosine kinase inhibitors (TKI) and reduced-dose chemotherapy for the treatment of patients with minimal residual disease (MRD) -positive and re…
View article: Stromal PLAU mediates tumor progression and informs a novel therapeutic target in triple-negative breast cancer
Stromal PLAU mediates tumor progression and informs a novel therapeutic target in triple-negative breast cancer Open
View article: Effects of chemical fertilization on bacterial community in rhizosphere soil of sugarcane
Effects of chemical fertilization on bacterial community in rhizosphere soil of sugarcane Open
Most sugarcane growing areas in China have undergone over 30 years of continuous monocropping, and long-term chemical fertilizer application has led to severe soil degradation. In order to provide a theoretical basis for the sustainable de…
View article: Eating behaviors among chinese older adults: A qualitative study using the capability, opportunity, motivation, and behavior model
Eating behaviors among chinese older adults: A qualitative study using the capability, opportunity, motivation, and behavior model Open
View article: Worldwide Research Trends on Lung Cancer and Microbiota: A Bibliometric and Visualized Analysis
Worldwide Research Trends on Lung Cancer and Microbiota: A Bibliometric and Visualized Analysis Open
This field has a bright research prospect, and there is a huge unmet clinical need. Future studies need to expand the sample size and further explore microbiota associated with the mechanisms, diagnosis, treatment and prognosis of lung can…
View article: Tissue Distribution and Biliary Excretion of a Classical Traditional Chinese Medicine Shengjiang Xiexin Decoction in Rats Analyzed by Ultra‐High Performance Liquid Chromatography Coupled to Mass Spectrometry
Tissue Distribution and Biliary Excretion of a Classical Traditional Chinese Medicine Shengjiang Xiexin Decoction in Rats Analyzed by Ultra‐High Performance Liquid Chromatography Coupled to Mass Spectrometry Open
The side effects caused by chemotherapeutic agent irinotecan (CPT‐11), such as diarrhea and steatosis, limit its clinical application. Shengjiang Xiexin decoction (SXD), a classical traditional Chinese medicine, is utilized to mitigate CPT…
View article: Letter to “Incidence of and Risk Factors for Neurological Deficits Associated With Percutaneous Vertebral Augmentation”
Letter to “Incidence of and Risk Factors for Neurological Deficits Associated With Percutaneous Vertebral Augmentation” Open
View article: Corrigendum to ‘Progressive Protocols for Pediatric Acute Lower Extremity Ischemia Postcatheterization Pediatric Lower Extremity Ischemia Protocol Postcatheterization’ Annals of Vascular Surgery 117 (2025) 92–102
Corrigendum to ‘Progressive Protocols for Pediatric Acute Lower Extremity Ischemia Postcatheterization Pediatric Lower Extremity Ischemia Protocol Postcatheterization’ Annals of Vascular Surgery 117 (2025) 92–102 Open
View article: Human Neural Stem Cells Reduce Hypoxia-Ischemic Neurological Impairment Through the Regulation of Inflammatory M1/M2 Microglias in Rats
Human Neural Stem Cells Reduce Hypoxia-Ischemic Neurological Impairment Through the Regulation of Inflammatory M1/M2 Microglias in Rats Open
hNSCs exerted beneficial effects on brain damage recovery and apoptosis suppression via paracrine actions of VEGF and BDNF, M1/M2 microglial balance regulation, cell differentiation promotion. The study underlined the potential of hNSC imp…
View article: Impact of Fungal Co-Infection on Teicoplanin Plasma Trough Concentration in Critically Ill Adults: A Novel Consideration for Dose Adjustment
Impact of Fungal Co-Infection on Teicoplanin Plasma Trough Concentration in Critically Ill Adults: A Novel Consideration for Dose Adjustment Open
For critically ill patients with fungal co-infections, the teicoplanin dose should be decreased, or at least not increased. This is essential for reducing the potential risk of toxicity and customizing dosing strategies to meet individual …
View article: Voxtalisib inhibits enterovirus 71 replication by downregulating host RAN and restoring IFN–STAT signaling
Voxtalisib inhibits enterovirus 71 replication by downregulating host RAN and restoring IFN–STAT signaling Open
RAN is a novel antiviral host target that indirectly mediates EV71 replication by regulating the nuclear-cytoplasmic transport of p-STAT1/2. Voxtalisib effectively restores IFN-STAT signaling by modulating RAN, offering a promising host-di…
View article: Concentration distribution and group disparity of traffic-derived NO<sub>2</sub> exposure in Baoshan District
Concentration distribution and group disparity of traffic-derived NO<sub>2</sub> exposure in Baoshan District Open
Motor vehicles are a major source of NO2 emissions, making traffic-related pollution a key target for urban air pollution control management. However, research on traffic-related NO2 exposure risks in China remains nascent, particularly re…
View article: H-BN/Cellulose insulation paper with high thermal conductivity, excellent mechanical strength, and electrical properties: Experimental and molecular dynamics study
H-BN/Cellulose insulation paper with high thermal conductivity, excellent mechanical strength, and electrical properties: Experimental and molecular dynamics study Open
With the rapid advancement of the power industry, transformers, as crucial components of power systems, require further improved insulation properties for their internal dielectric materials. This study aims to improve the thermal conducti…