Fuqiang Wen
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Author Swipe
View article: Efficacy, pharmacokinetics, and safety of nebulized HL231 inhalation solution in patients with chronic obstructive pulmonary disease: a randomized trial
Efficacy, pharmacokinetics, and safety of nebulized HL231 inhalation solution in patients with chronic obstructive pulmonary disease: a randomized trial Open
This study was registered at Chinese Clinical Trials Registration (ChiCTR2300068316) and clinicaltrials.gov (NCT06619210, retrospectively registered).
View article: Predictive value of frailty and nutritional status for hospital acquired pneumonia in elderly patients undergoing vascular surgeries
Predictive value of frailty and nutritional status for hospital acquired pneumonia in elderly patients undergoing vascular surgeries Open
Background Hospital acquired pneumonia (HAP) is one of the most common types of nosocomial infections, and closely related to poor prognosis. The present study intends to explore the predictive value of preoperative frailty and nutritional…
View article: Global, regional, and national temporal trend in burden of chronic respiratory diseases from 1990 to 2021: Findings from the Global Burden of Disease Study 2021
Global, regional, and national temporal trend in burden of chronic respiratory diseases from 1990 to 2021: Findings from the Global Burden of Disease Study 2021 Open
Background: Chronic respiratory diseases (CRDs), including chronic obstructive pulmonary disease (COPD), asthma, pneumoconiosis, interstitial lung disease (ILD), and pulmonary sarcoidosis, continue to pose a significant global health chall…
View article: Predictors of COPD exacerbations differ between grades of airflow limitation
Predictors of COPD exacerbations differ between grades of airflow limitation Open
Background History of exacerbations is a predictor of future exacerbations in COPD but there are also predictors that are independent of exacerbation history. However, it is unclear whether their relative contribution is consistent across …
View article: Clinical characteristics and economic burden of hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease in the Chinese Yi population
Clinical characteristics and economic burden of hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease in the Chinese Yi population Open
Purpose The study aimed to compare the clinical characteristics and economic burden of Yi and Han hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Patients and methods The patients hospitaliz…
View article: Development and validation of a prediction model based on a nomogram for tuberculous pleural effusion
Development and validation of a prediction model based on a nomogram for tuberculous pleural effusion Open
Background Diagnosing tuberculous pleural effusion (TPE) is challenging. There is a lack of cross-sectional lateral comparisons among TPE prediction models. Objectives We aimed to develop and validate a novel TPE prediction model and compa…
View article: Association of hs-CRP/HDL, AIP and NHHR with chronic obstructive pulmonary disease: a cross-sectional NHANES study
Association of hs-CRP/HDL, AIP and NHHR with chronic obstructive pulmonary disease: a cross-sectional NHANES study Open
The study suggests elevated hs-CRP/HDL may related to COPD, suggesting its potential as diagnostic marker for COPD.
View article: DNA methylation and bronchiectasis: a Mendelian randomization analysis to investigate causal link and therapeutic target
DNA methylation and bronchiectasis: a Mendelian randomization analysis to investigate causal link and therapeutic target Open
This study aims to discover drug targeted genes and explore the potential epigenetics mechanisms in bronchiectasis. Cis-expression quantitative trait locus (eQTL) was obtained as exposure, and bronchiectasis from the FinnGen cohort was use…
View article: Clinical Application Guideline of Combination With Traditional Chinese Medicine and Western Medicine in the Prevention and Treatment of Chronic Obstructive Pulmonary Disease (2024)
Clinical Application Guideline of Combination With Traditional Chinese Medicine and Western Medicine in the Prevention and Treatment of Chronic Obstructive Pulmonary Disease (2024) Open
Aim Chronic Obstructive Pulmonary Disease (COPD) is a common chronic airway disease that can lead to decreased lung function in patients. It places a heavy economic burden on patients and society. Traditional Chinese medicine (TCM) and Wes…
View article: The availability of drugs for stable COPD treatment in China: a cross-sectional survey
The availability of drugs for stable COPD treatment in China: a cross-sectional survey Open
View article: Impact of Housing Characteristics and Indoor Environmental Factors on Chronic Obstructive Pulmonary Disease: Findings from the China Pulmonary Health (Cph) Study
Impact of Housing Characteristics and Indoor Environmental Factors on Chronic Obstructive Pulmonary Disease: Findings from the China Pulmonary Health (Cph) Study Open
View article: Typical Case of Converter Smelting with High Cooling Ratio in Chinese Iron and Steel Enterprises: CO2 Emission Analysis
Typical Case of Converter Smelting with High Cooling Ratio in Chinese Iron and Steel Enterprises: CO2 Emission Analysis Open
In this study, the effects of using different scrap ratios in a converter on carbon emissions were analyzed based on life cycle assessment (LCA) theory, and the carbon emissions from the converter were evaluated with the use of coke and bi…
View article: Beclometasone Dipropionate/Formoterol Fumarate is Similarly Effective to Budesonide/Formoterol Fumarate in Chinese Patients with COPD: The FORSYYN Double-Blind, Randomised Study
Beclometasone Dipropionate/Formoterol Fumarate is Similarly Effective to Budesonide/Formoterol Fumarate in Chinese Patients with COPD: The FORSYYN Double-Blind, Randomised Study Open
China Centre for Drug Evaluation (CTR20180475).
View article: Diagnostic value of impulse oscillometry in chronic obstructive pulmonary disease: a multicentre, retrospective, observational study
Diagnostic value of impulse oscillometry in chronic obstructive pulmonary disease: a multicentre, retrospective, observational study Open
Objectives Diagnosis and assessment of chronic obstructive pulmonary disease (COPD) rely extensively on spirometry, which necessitates patient cooperation. The clinical value of impulse oscillometry (IOS) as a non-volitional method in pati…
View article: Application of metagenomic next-generation sequencing in the etiological diagnosis of refractory pneumonia in children
Application of metagenomic next-generation sequencing in the etiological diagnosis of refractory pneumonia in children Open
Objective Metagenomic next-generation sequencing (mNGS) was used to analyze the etiological distribution of refractory pneumonia in children. We compared its efficacy in pathogen diagnosis against traditional methods to provide a basis for…
View article: DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease
DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease Open
Chronic obstructive pulmonary disease (COPD) is characterised by persistent airway inflammation even after cigarette smoking cessation. Neutrophil extracellular traps (NETs) have been implicated in COPD severity and acute airway inflammati…
View article: Bacterial interactome disturbance in chronic obstructive pulmonary disease clinical stability and exacerbations
Bacterial interactome disturbance in chronic obstructive pulmonary disease clinical stability and exacerbations Open
View article: Hospital readmissions and mortality among fee-for-service medicare patients with minor stroke or transient ischemic attack: Findings from the COMPASS cluster-randomized pragmatic trial
Hospital readmissions and mortality among fee-for-service medicare patients with minor stroke or transient ischemic attack: Findings from the COMPASS cluster-randomized pragmatic trial Open
Background Mortality and hospital readmission rates may reflect the quality of acute and postacute stroke care. Our aim was to investigate if, compared with usual care (UC), the COMPASS-TC (Comprehensive Post-Acute Stroke Services Transiti…
View article: Associations between mixed exposure to phthalates and latent tuberculosis infection among the general U.S. population from NHANES 2011–2012
Associations between mixed exposure to phthalates and latent tuberculosis infection among the general U.S. population from NHANES 2011–2012 Open
View article: Mediating Effect of Tobacco Dependence on the Association Between Maternal Smoking During Pregnancy and Chronic Obstructive Pulmonary Disease: Case-Control Study
Mediating Effect of Tobacco Dependence on the Association Between Maternal Smoking During Pregnancy and Chronic Obstructive Pulmonary Disease: Case-Control Study Open
Background Maternal smoking during pregnancy (MSDP) is a known risk factor for offspring developing chronic obstructive pulmonary disease (COPD), but the underlying mechanism remains unclear. Objective This study aimed to explore whether t…
View article: Differential expression profiles and functional prediction of circular RNAs in lung cancer patients with chronic obstructive pulmonary disease: a pilot study
Differential expression profiles and functional prediction of circular RNAs in lung cancer patients with chronic obstructive pulmonary disease: a pilot study Open
Chronic obstructive pulmonary disease (COPD), characterized by clinical sub-phenotypes such as emphysema (E) and chronic bronchitis (CB), is associated with a greater risk of lung cancer (LC). This study aimed to assess the expression patt…
View article: A simple and efficient clinical prediction scoring system to identify malignant pleural effusion
A simple and efficient clinical prediction scoring system to identify malignant pleural effusion Open
Background: Early diagnosis of malignant pleural effusion (MPE) is of great significance. Current prediction models are not simple enough to be widely used in heavy clinical work. Objectives: We aimed to develop a simple and efficient clin…
View article: Enhanced Photocatalytic Degradation of Polycyclic Aromatic Hydrocarbons (Pahs) in Biochar Using Nano-Tio2 Under Ultraviolet Light Irradiation: Effect and Mechanisms
Enhanced Photocatalytic Degradation of Polycyclic Aromatic Hydrocarbons (Pahs) in Biochar Using Nano-Tio2 Under Ultraviolet Light Irradiation: Effect and Mechanisms Open
View article: Research progress of mitochondria in chronic obstructive pulmonary disease: a bibliometric analysis based on the Web of Science Core Collection
Research progress of mitochondria in chronic obstructive pulmonary disease: a bibliometric analysis based on the Web of Science Core Collection Open
BACKGROUND: Due to its high morbidity and mortality, chronic obstructive pulmonary disease (COPD) has become a major global healthcare issue. Although there is abundant research regarding COPD, a bibliometric analysis of the literature rel…
View article: Single‐cell <scp>RNA</scp> sequencing reveals immune microenvironment of small cell lung cancer‐associated malignant pleural effusion
Single‐cell <span>RNA</span> sequencing reveals immune microenvironment of small cell lung cancer‐associated malignant pleural effusion Open
We used 10 × genomics single‐cell transcriptome sequencing technology to reveal the tumor immune microenvironment characteristics of small cell lung cancer (SCLC) in a patient with malignant pleural effusion (MPE). A total of 8008 high‐qua…
View article: A Peripheral Blood Transcriptomic Biomarker Panel Identified by Multiple Machine Learning Algorithms Enables Early Diagnosis and Prognosis Prediction in Lung Cancer
A Peripheral Blood Transcriptomic Biomarker Panel Identified by Multiple Machine Learning Algorithms Enables Early Diagnosis and Prognosis Prediction in Lung Cancer Open
Background Lung cancer is the leading cause of malignancy-associated mortality worldwide. Early-stage lung cancer often manifests without typical symptoms, frequently leading to late-stage diagnoses and grim prognoses. Therefore, the timel…
View article: Guideline on treating community-acquired pneumonia with Chinese patent medicines
Guideline on treating community-acquired pneumonia with Chinese patent medicines Open
Community-acquired pneumonia (CAP) is one of the most common infectious diseases, and its morbidity and mortality increase with age. Resistance and mutations development make the use of anti-infective therapy challenging. Chinese patent me…
View article: Graphical Abstract: Angew. Chem. Int. Ed. 35/2023
Graphical Abstract: Angew. Chem. Int. Ed. 35/2023 Open
In their Research Article (e202302003), Daniel Huster et al. analyze the dynamics of the human growth hormone secretagogue receptor.The study reveals insights into the energy landscape of the molecule.
View article: Graphisches Inhaltsverzeichnis: Angew. Chem. 35/2023
Graphisches Inhaltsverzeichnis: Angew. Chem. 35/2023 Open
…, despite its strongly hydrophilic nature, exhibits hydrophobic behaviour when immersed in water.This effect is induced by the first water layer that is in immediate contact with the hydroxylated CeO 2 (100) surface.This ordered water lay…
View article: Incorporation of a Toll-like receptor 2/6 agonist potentiates mRNA vaccines against cancer and infectious diseases
Incorporation of a Toll-like receptor 2/6 agonist potentiates mRNA vaccines against cancer and infectious diseases Open