Qiangqiang Zheng
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View article: Robot-assisted minimally invasive esophagectomy versus video-assisted thoracoscopic esophagectomy versus open esophagectomy for locally advanced esophageal cancer after neoadjuvant therapy: a systematic review and network meta-analysis
Robot-assisted minimally invasive esophagectomy versus video-assisted thoracoscopic esophagectomy versus open esophagectomy for locally advanced esophageal cancer after neoadjuvant therapy: a systematic review and network meta-analysis Open
Background Esophageal cancer (EC) remains a lethal malignancy with poor survival outcomes despite multimodal therapy. While minimally invasive techniques like video-assisted thoracoscopic esophagectomy (VATE) and robot-assisted minimally i…
View article: Perioperative outcomes in lung cancer: transfer vs. outpatient admission routes
Perioperative outcomes in lung cancer: transfer vs. outpatient admission routes Open
View article: Which is the best surgical approach for thymectomy: robot-assisted thoracoscopic surgery (RATS), video-assisted thoracoscopic surgery (VATS), thoracotomy (TORA) or subxiphoid video-assisted thoracoscopic surgery (SPT)?—a systematic review and network meta-analysis
Which is the best surgical approach for thymectomy: robot-assisted thoracoscopic surgery (RATS), video-assisted thoracoscopic surgery (VATS), thoracotomy (TORA) or subxiphoid video-assisted thoracoscopic surgery (SPT)?—a systematic review and network meta-analysis Open
SPT has faster postoperative recovery and less postoperative pain, and other perioperative outcomes are not inferior to other surgical approaches. RATS is safer and has certain clinical advantages in CSR. We look forward to more large-samp…
View article: Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy
Relationship between gender and perioperative clinical features in lung cancer patients who underwent VATS lobectomy Open
Compared with female patients, male patients with lung cancer are more likely to have unfavorable factors such as older age, higher smoking rate, poor pulmonary function and late clinical stage of tumors when they undergoing VATS surgery t…
View article: Which is the best surgical approaches for thymectomy: RATS, VATS, TORA or SPT? A network meta-analysis
Which is the best surgical approaches for thymectomy: RATS, VATS, TORA or SPT? A network meta-analysis Open
Purpose T hymectomy is indicated in the presence of primary thymic diseases such as thymoma. However, there is no clear conclusion which is the best surgical approaches for thymectomy. We performed this network meta-analysis (NMA) to explo…
View article: A ferroptosis-related gene signature and immune infiltration for predicting the lymph node metastasis of patients with lung adenocarcinoma
A ferroptosis-related gene signature and immune infiltration for predicting the lymph node metastasis of patients with lung adenocarcinoma Open
Background The lymph node metastasis of LUAD is a pivotal factor leading to late TNM staging and poor prognosis. Ferroptosis plays a key role in promoting cancer cell death and immunotherapy. However, the roles of FRGs in lymph node metast…
View article: Acute cardiac tamponade following thoracoscopic lobectomy: a case report and literatures review
Acute cardiac tamponade following thoracoscopic lobectomy: a case report and literatures review Open
View article: Exosome-laden injectable self-healing hydrogel based on quaternized chitosan and oxidized starch attenuates disc degeneration by suppressing nucleus pulposus senescence
Exosome-laden injectable self-healing hydrogel based on quaternized chitosan and oxidized starch attenuates disc degeneration by suppressing nucleus pulposus senescence Open
Disc degeneration is the common pathology underlying various degenerative spinal disorders and currently there is no effective cure. Here, we found nucleus pulposus (NP) cell senescence was closely associated with the severity of disc dege…
View article: Feasibility and oncological outcomes of video‐assisted thoracic surgery versus thoracotomy for pathologic <scp>N2</scp> disease in non–small cell lung cancer: A comprehensive systematic review and meta‐analysis
Feasibility and oncological outcomes of video‐assisted thoracic surgery versus thoracotomy for pathologic <span>N2</span> disease in non–small cell lung cancer: A comprehensive systematic review and meta‐analysis Open
This meta‐analysis aimed to evaluate the feasibility and oncological outcomes between video‐assisted thoracic surgery (VATS) and thoracotomy for non–small cell lung cancer (NSCLC) patients with pathologic N2 (pN2) disease. Data for analysi…
View article: A network meta-analysis for efficacies and toxicities of different concurrent chemoradiotherapy regimens in the treatment of locally advanced non-small cell lung cancer
A network meta-analysis for efficacies and toxicities of different concurrent chemoradiotherapy regimens in the treatment of locally advanced non-small cell lung cancer Open
Background Concurrent chemoradiotherapy (CCRT) has become the cornerstone of treatment for patients with locally advanced non-small cell lung cancer (LA-NSCLC). The aim of this study was to compare the efficacies and toxicities of differen…
View article: Wedge Resection vs. Stereotactic Body Radiation Therapy for Clinical Stage I Non-small Cell Lung Cancer: A Systematic Review and Meta-Analysis
Wedge Resection vs. Stereotactic Body Radiation Therapy for Clinical Stage I Non-small Cell Lung Cancer: A Systematic Review and Meta-Analysis Open
Background Whether wedge resection or stereotactic body radiation therapy (SBRT) has better effectiveness in treatment of clinical stage I non-small cell lung cancer (NSCLC) patients remains unclear. Here we conducted the first meta-analys…
View article: Comprehensive Analysis of The Expression and Prognosis For KRTs in LUSC Based on Bioinformatics Analysis
Comprehensive Analysis of The Expression and Prognosis For KRTs in LUSC Based on Bioinformatics Analysis Open
Keratins (KRTs), a family of genes that encode a series of intermediate flament proteins, which expressed in epithelial cells of various tissues and had been identified as being involved in various tumors. Previous evidences indicated that…
View article: Identification of potential diagnostic and prognostic biomarkers for LUAD based on TCGA and GEO databases
Identification of potential diagnostic and prognostic biomarkers for LUAD based on TCGA and GEO databases Open
Accumulating evidence has demonstrated that gene alterations play a crucial role in LUAD development, progression, and prognosis. The present study aimed to identify the hub genes associated with LUAD. In the present study, we used TCGA da…
View article: Efficacy and Toxicity of Different Concurrent Chemoradiotherapy Regimens in Patients With Locally Advanced Non-Small Cell Lung Cancer-a Network Meta-Analysis
Efficacy and Toxicity of Different Concurrent Chemoradiotherapy Regimens in Patients With Locally Advanced Non-Small Cell Lung Cancer-a Network Meta-Analysis Open
Background: Concurrent chemoradiotherapy (CCRT) is the cornerstone treatment for patients with locally advanced non-small cell lung cancer (LA-NSCLC). The aim of this study was to compare the efficacy and toxicity of different CCRT regimen…
View article: A Deep-Learning–Based, Fully Automated Program to Segment and Quantify Major Spinal Components on Axial Lumbar Spine Magnetic Resonance Images
A Deep-Learning–Based, Fully Automated Program to Segment and Quantify Major Spinal Components on Axial Lumbar Spine Magnetic Resonance Images Open
Objective The paraspinal muscles have been extensively studied on axial lumbar magnetic resonance imaging (MRI) for better understanding of back pain; however, the acquisition of measurements mainly relies on manual segmentation, which is …
View article: Nm23‐H1 inhibits lung cancer bone‐specific metastasis by upregulating miR‐660‐5p targeted SMARCA5
Nm23‐H1 inhibits lung cancer bone‐specific metastasis by upregulating miR‐660‐5p targeted SMARCA5 Open
Background Nm23‐H1 gene has been found to be an inhibitor of tumor metastasis in lung cancer. MicroRNAs (miRNAs) play key roles in tumor metastasis through multiple signaling pathways. This study explored whether the nm23‐H1 gene could inh…
View article: [A Meta-Analysis of Efficacy and Adverse Effects of Lobaplatin and Cisplatin in the Treatment of Malignant Pleural Effusion].
[A Meta-Analysis of Efficacy and Adverse Effects of Lobaplatin and Cisplatin in the Treatment of Malignant Pleural Effusion]. Open
Compared with DDP pleural perfusion chemotherapy, the ORR, CR and PR of LBP pleural perfusion chemotherapy for MPE are significantly better than DDP, and its nephrotoxicity and gastrointestinal reactions are remarkably lower than DDP.