Qianqian Zhao
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View article: <scp>ScHAL1</scp> ‐Mediated Enhancement of Salt Tolerance in Soybean: From Stable Transgenic Inheritance to Field Trial Validation
<span>ScHAL1</span> ‐Mediated Enhancement of Salt Tolerance in Soybean: From Stable Transgenic Inheritance to Field Trial Validation Open
To develop salt‐tolerant transgenic soybeans, ScHAL1 from Saccharomyces cerevisiae (yeast), which increases salt tolerance by maintaining high intracellular K + concentrations and decreasing intracellular Na + during salt stress, was intro…
View article: 311 Inhibition of PTPN2/N1 by the small molecule inhibitor ABBV-CLS-484 enhances the efficacy of adoptive T cell therapy
311 Inhibition of PTPN2/N1 by the small molecule inhibitor ABBV-CLS-484 enhances the efficacy of adoptive T cell therapy Open
View article: Integrative genomics reveals PDE11A and SAAL are key regulators of growth in Pacific white shrimp (Penaeus vannamei)
Integrative genomics reveals PDE11A and SAAL are key regulators of growth in Pacific white shrimp (Penaeus vannamei) Open
View article: Factors Associated with Functional Outcome Following Acute Ischemic Stroke Due to M1 MCA/ICA Occlusion in the Extended Time Window
Factors Associated with Functional Outcome Following Acute Ischemic Stroke Due to M1 MCA/ICA Occlusion in the Extended Time Window Open
Introduction: A validated clinical decision tool predictive of favorable functional outcomes following endovascular thrombectomy (EVT) in acute ischemic stroke (AIS) remains elusive. We performed a retrospective case series of patients at …
View article: An easily overlooked cause of pulmonary arterial hypertension—thiamine deficiency
An easily overlooked cause of pulmonary arterial hypertension—thiamine deficiency Open
Thiamine deficiency (TD), also known as vitamin B1 deficiency, is an often overlooked potential cause of pulmonary arterial hypertension (PAH). It may contribute to the pathological process of PAH through the deficiency of related coenzyme…
View article: Medical Information Provided by Transgender and Gender-Diverse Content Creators on YouTube: Descriptive Content Analysis
Medical Information Provided by Transgender and Gender-Diverse Content Creators on YouTube: Descriptive Content Analysis Open
Background Transgender and gender-diverse (TGD) individuals frequently turn to social media to find community, express their identities, and access essential information. These platforms are easily accessible to TGD people and enable healt…
View article: High performance tungsten-doped VO<sub>2</sub> polycrystalline films for advanced dynamic radiant thermal management
High performance tungsten-doped VO<sub>2</sub> polycrystalline films for advanced dynamic radiant thermal management Open
The utilization of W-doped VO 2 (W x V 1− x O 2 ) for dynamic radiative thermal management (DRTM) is a breakthrough in refrigeration technology, gaining attention for its energy efficiency and environmental benefits. The W x V 1− x O 2 -ba…
View article: Pairing a Validated Alcohol Intervention With Social Media Alcohol Risk Identification: Impact on Alcohol Behaviors and Social Media Posts
Pairing a Validated Alcohol Intervention With Social Media Alcohol Risk Identification: Impact on Alcohol Behaviors and Social Media Posts Open
View article: Medical Information Provided by Transgender and Gender Diverse Content Creators on YouTube: Qualitative Analysis (Preprint)
Medical Information Provided by Transgender and Gender Diverse Content Creators on YouTube: Qualitative Analysis (Preprint) Open
BACKGROUND Transgender and gender diverse (TGD) individuals often turn to online platforms for information about gender-affirming healthcare. YouTube, a widely used video-sharing platform, hosts content from popular TGD creators that may …
View article: Comparison of two active warming techniques on body temperature in healthy, anesthetized dogs premedicated with acepromazine or dexmedetomidine: A pilot study
Comparison of two active warming techniques on body temperature in healthy, anesthetized dogs premedicated with acepromazine or dexmedetomidine: A pilot study Open
Temperature regulation in dogs is significantly impaired during general anesthesia. Glabrous skin on paws may facilitate thermoregulation from this area and is a potential target for interventions attenuating hypothermia. This pilot study …
View article: Accuracy of a flash glucose monitoring system in healthy dogs during isoflurane anesthesia
Accuracy of a flash glucose monitoring system in healthy dogs during isoflurane anesthesia Open
OBJECTIVE To assess the accuracy of a flash glucose monitoring system (FGMS; FreeStyle Libre 2) in healthy dogs during isoflurane general anesthesia. METHODS 6 purpose-bred Beagle dogs underwent 3 anesthetic events, 1 week apart, in a rand…
View article: Oral trazodone results in quantifiable sedation but does not result in a xylazine-sparing effect in healthy adult horses
Oral trazodone results in quantifiable sedation but does not result in a xylazine-sparing effect in healthy adult horses Open
OBJECTIVE To evaluate sedation and IV xylazine requirements to achieve 45% of baseline head height above ground measurements following oral (PO) administration of 2 trazodone dosages. METHODS 8 healthy, adult mares of various weights and b…
View article: Physiologic and behavioral effects of long-acting subcutaneous and transdermal buprenorphine in rats
Physiologic and behavioral effects of long-acting subcutaneous and transdermal buprenorphine in rats Open
OBJECTIVE To investigate thermoregulation, thermal antinociception, food/kaolin intake, fecal output, and behavior following long-acting buprenorphine preparations in rats. ANIMALS 8 adult male rats ( Rattus norvegicus ) were administered …
View article: Disparities in COVID-19 vaccine intentions, testing and trusted sources by household language for children with medical complexity
Disparities in COVID-19 vaccine intentions, testing and trusted sources by household language for children with medical complexity Open
Objectives Children with medical complexity experienced health disparities during the coronavirus disease 2019 (COVID-19) pandemic. Language may compound these disparities since people speaking languages other than English (LOE) also exper…
View article: Corrigendum to: TMEM106A transcriptionally regulated by promoter methylation is involved in invasion and metastasis of hepatocellular carcinoma
Corrigendum to: TMEM106A transcriptionally regulated by promoter methylation is involved in invasion and metastasis of hepatocellular carcinoma Open
In the version of this article initially published, an error was found in Figure 5D.The correct figure is as follows, and the interpretation of the results should be amended as follows: Matrigel invasion assay demonstrated that HepG2-shTME…
View article: Research on the revenue prospect for energy storage participation in electricity spot and FM auxiliary service markets —Considering capacity market mechanisms
Research on the revenue prospect for energy storage participation in electricity spot and FM auxiliary service markets —Considering capacity market mechanisms Open
The vigorous development of energy storage is significant in supporting new energy consumption and enhancing the power system regulation capability. The spot and auxiliary service markets are the core ways for energy storage to realize com…
View article: Use of gender‐inclusive language in genetic counseling to optimize patient care
Use of gender‐inclusive language in genetic counseling to optimize patient care Open
Providing welcoming, inclusive, and culturally competent care is essential for genetic counselors (GCs) to serve the needs of all patients, including transgender and nonbinary (TGNB) individuals. Inclusive language creates welcoming health…
View article: 经口机器人手术治疗喉下咽食管入口孤立性纤维性肿瘤1例并文献复习
经口机器人手术治疗喉下咽食管入口孤立性纤维性肿瘤1例并文献复习 Open
To explore the clinical diagnosis and treatment experience of isolated fibrotic tumor (SFT) occurring in the larynx, hypopharynx and esophageal inlet with a wide range.The patient, admitted to the Department of Otolaryngology-Head and Neck…
View article: Author Correction: Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial
Author Correction: Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial Open
View article: Regenerable and Stable Olefin-Linked Covalent Organic Frameworks with Coordination Template for Selective and Efficient Trapping of Scandium Ion
Regenerable and Stable Olefin-Linked Covalent Organic Frameworks with Coordination Template for Selective and Efficient Trapping of Scandium Ion Open
View article: Individualized Pricing of User-Side Shared Energy Storage
Individualized Pricing of User-Side Shared Energy Storage Open
View article: Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial
Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial Open
Cystectomy is a standard treatment for muscle-invasive bladder cancer (MIBC), but it is life-altering. We initiated a phase 2 study in which patients with MIBC received four cycles of gemcitabine, cisplatin, plus nivolumab followed by clin…
View article: Coordinated Priming of NKG2D Pathway by IL-15 Enhanced Functional Properties of Cytotoxic CD4+CD28− T Cells Expanded in Systemic Lupus Erythematosus
Coordinated Priming of NKG2D Pathway by IL-15 Enhanced Functional Properties of Cytotoxic CD4+CD28− T Cells Expanded in Systemic Lupus Erythematosus Open
Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder, and numerous aberrations of T cell responses have been reported and were implicated in its pathophysiology. Recently, CD4-positive T cells with cytotoxic potential were …
View article: Molecular Characterization and Treatment Approaches for Pediatric H3 K27-Altered Diffuse Midline Glioma: Integrated Systematic Review of Individual Clinical Trial Participant Data
Molecular Characterization and Treatment Approaches for Pediatric H3 K27-Altered Diffuse Midline Glioma: Integrated Systematic Review of Individual Clinical Trial Participant Data Open
Diffuse midline glioma (DMG), H3 K27-altered are highly aggressive, incurable central nervous system (CNS) tumors. The current standard palliative treatment is radiotherapy, with most children succumbing to the disease in less than one yea…
View article: School Attendance Decisions for Children With Medical Complexity During COVID-19
School Attendance Decisions for Children With Medical Complexity During COVID-19 Open
OBJECTIVE School attendance by children with medical complexity (CMC) may be influenced by parent perceptions of their child’s risk for coronavirus disease 2019 (COVID-19). The authors of this study aimed to quantify in-person school atten…
View article: “Non-criteria” antiphospholipid antibodies aid risk stratification in autoimmune recurrent pregnancy loss
“Non-criteria” antiphospholipid antibodies aid risk stratification in autoimmune recurrent pregnancy loss Open
Recurrent pregnancy loss (RPL) is a serious pregnancy disease caused by a variety of factors. Obstetric antiphospholipid syndrome (OAPS) is the most prevalent treatable cause of RPL. Although some RPL patients do not meet the diagnosis of …
View article: Empagliflozin ameliorates diabetic cardiomyopathy via regulated branched-chain amino acid metabolism and mTOR/p-ULK1 signaling pathway-mediated autophagy
Empagliflozin ameliorates diabetic cardiomyopathy via regulated branched-chain amino acid metabolism and mTOR/p-ULK1 signaling pathway-mediated autophagy Open
Background Empagliflozin, a sodium–glucose co-transporter 2 inhibitor (SGLT2i), has been reported to significantly reduce the risk of heart failure in multiple clinical studies. However, the underlying mechanisms remain elusive. This study…
View article: Study on the pharmacological mechanisms of sodium-glucose co-transporter 2 inhibitors in obesity-related atrial fibrillation based on network pharmacology and experimental verification
Study on the pharmacological mechanisms of sodium-glucose co-transporter 2 inhibitors in obesity-related atrial fibrillation based on network pharmacology and experimental verification Open
In this study, pharmacological network analysis and in vivo experiments demonstrated that SGLT2i acts on obesity-related AF by inhibiting the AGE-RAGE signaling pathway. These results offer fresh perspectives on the pharmacological …
View article: IL-15 enhances functional properties and responses of cytotoxic CD4<sup>+</sup>CD28<sup>−</sup>T cells expanded in Systemic lupus erythematosus
IL-15 enhances functional properties and responses of cytotoxic CD4<sup>+</sup>CD28<sup>−</sup>T cells expanded in Systemic lupus erythematosus Open
Systemic lupus erythematosus (SLE) is an autoimmune disorder that results in an attack by body’s immune system of its own tissues, causing chronic inflammation and tissue damage. T cells play a key role in the pathogenesis of SLE, as they …
View article: In Situ Self-Heterogenization of Cu2s/Cus Nanostructures with Modulated D Band Centers for Promoting Photocatalytic Degradation and Hydrogen Evolution Performances
In Situ Self-Heterogenization of Cu2s/Cus Nanostructures with Modulated D Band Centers for Promoting Photocatalytic Degradation and Hydrogen Evolution Performances Open