Rongqiao He
YOU?
Author Swipe
View article: Niacin enhances hematoma clearance and neurological recovery via the HCAR2/SIRT1/Nrf2 pathway after germinal matrix hemorrhage
Niacin enhances hematoma clearance and neurological recovery via the HCAR2/SIRT1/Nrf2 pathway after germinal matrix hemorrhage Open
View article: Case Series and Literature Review on Tofacitinib for Treating Severe Alopecia Areata
Case Series and Literature Review on Tofacitinib for Treating Severe Alopecia Areata Open
This study supports the efficacy and safety of tofacitinib in AA treatment, providing further clinical evidence for its application.
View article: Dynamic Modeling and Coning Motion Characteristic Analysis of Object-Parachute System
Dynamic Modeling and Coning Motion Characteristic Analysis of Object-Parachute System Open
In response to the challenges of high model dimensionality, pronounced rigid-flexible characteristics, and experimental difficulties encountered in the stable descent phase of object-parachute systems, this study investigates numerical sim…
View article: Targeting the glymphatic system: Aβ accumulation and phototherapy strategies across different stages of Alzheimer’s disease
Targeting the glymphatic system: Aβ accumulation and phototherapy strategies across different stages of Alzheimer’s disease Open
The glymphatic system serves as the brain’s clearance system. It deteriorates with age and is a significant contributor to the onset and progression of Alzheimer’s disease (AD). Modulating cerebrospinal fluid (CSF)-based clearance and targ…
View article: Analysis of risk factors for poor prognosis after endovascular treatment of tandem lesions in acute ischemic stroke
Analysis of risk factors for poor prognosis after endovascular treatment of tandem lesions in acute ischemic stroke Open
Aims/background In China, the incidence of acute ischemic stroke (AIS) has been rising annually, accounting for 60–70% of all stroke cases. To explore the risk factors leading to poor prognosis after endovascular treatment in patients with…
View article: 6G ISAC Enables Environment Object Reconstruction
6G ISAC Enables Environment Object Reconstruction Open
View article: Alterations of the skin microbiome in multiple system atrophy: a pilot study
Alterations of the skin microbiome in multiple system atrophy: a pilot study Open
Multiple system atrophy (MSA) alters skin physiology, potentially impacting skin microbiota. This pilot study investigated whether skin microbiota differs in MSA and whether these differences relate to disease severity. Using 16S rRNA sequ…
View article: Considerations for the Treatment Strategy of Relapse After Tofacitinib Therapy in Alopecia Areata
Considerations for the Treatment Strategy of Relapse After Tofacitinib Therapy in Alopecia Areata Open
Background Alopecia areata (AA) is an autoimmune disorder mediated by T cells, resulting in hair loss on the scalp, eyebrows, and body. Conventional treatments for AA often exhibit high recurrence rates and various side effects. Recently, …
View article: Age-related stress gene expression in neonatal sepsis involves regulatory networks and immune cell infiltration
Age-related stress gene expression in neonatal sepsis involves regulatory networks and immune cell infiltration Open
View article: Age-related stress gene expression in neonatal sepsis involves regulatory networks and immune cell infiltration
Age-related stress gene expression in neonatal sepsis involves regulatory networks and immune cell infiltration Open
Septicemia triggers a profound systemic inflammatory response, ultimately leading to cellular senescence. Understanding the mechanisms underlying intercellular interactions associated with sepsis is crucial for developing therapeutic strat…
View article: Dynamic topological charge switching in vortex beam generation using phase-change materials
Dynamic topological charge switching in vortex beam generation using phase-change materials Open
This study employs the phase-change material Sb 2 S 3 to design a tunable vortex beam (VB) generator based on bound states in the continuum (BICs). Sb 2 S 3 exhibits a significant contrast in refractive indices between its amorphous and cr…
View article: Regional tissue oxygen saturation during minimal enteral feeding is associated with the subsequent feeding intolerance in very preterm infants
Regional tissue oxygen saturation during minimal enteral feeding is associated with the subsequent feeding intolerance in very preterm infants Open
Feeding intolerance (FI) is a common clinical problem in very preterm infants (VPIs) and it increases the risk for adverse outcomes. The value of regional tissue oxygen saturation in predicting FI remains unclear. A total of 57 VPIs were i…
View article: Multiple time points of transcriptome analysis revealed altered genes involved in maintaining hibernation in the hypothalamus of Tamias sibiricus
Multiple time points of transcriptome analysis revealed altered genes involved in maintaining hibernation in the hypothalamus of Tamias sibiricus Open
Hibernation, an adaptive mechanism to extreme environmental conditions, is prevalent among mammals. Its main characteristics include reduced body temperature and metabolic rate. However, the mechanisms by which hibernating animals re-enter…
View article: Correction: Chen et al. The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment. Pharmaceutics 2023, 15, 1568
Correction: Chen et al. The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment. Pharmaceutics 2023, 15, 1568 Open
In the original publication [...]
View article: Oxysterol binding protein (OSBP) contributes to hepatitis E virus replication
Oxysterol binding protein (OSBP) contributes to hepatitis E virus replication Open
View article: Initial COVID-19 severity influenced by SARS-CoV-2-specific T cells imprints T-cell memory and inversely affects reinfection
Initial COVID-19 severity influenced by SARS-CoV-2-specific T cells imprints T-cell memory and inversely affects reinfection Open
The immunoprotective components control COVID-19 disease severity, as well as long-term adaptive immunity maintenance and subsequent reinfection risk discrepancies across initial COVID-19 severity, remain unclarified. Here, we longitudinal…
View article: Glycolytic Pathways: The Hidden Regulators in Parkinson's Disease
Glycolytic Pathways: The Hidden Regulators in Parkinson's Disease Open
View article: Immune escape of BA.2.86 is comparable to XBB subvariants from the plasma of BA.5‐ and BA.5‐XBB‐convalescent subpopulations
Immune escape of BA.2.86 is comparable to XBB subvariants from the plasma of BA.5‐ and BA.5‐XBB‐convalescent subpopulations Open
The EG.5.1 variant of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) has been prevalent since mid‐July 2023 in the United States and China. The variant BA.2.86 has become a major concern because it is 34 mutations away from t…
View article: Single-cell and bulk RNA sequencing reveal heterogeneity and diagnostic markers in papillary thyroid carcinoma lymph-node metastasis
Single-cell and bulk RNA sequencing reveal heterogeneity and diagnostic markers in papillary thyroid carcinoma lymph-node metastasis Open
View article: KCNN1 promotes proliferation and metastasis of breast cancer via ERLIN2-mediated stabilization and K63-dependent ubiquitination of Cyclin B1
KCNN1 promotes proliferation and metastasis of breast cancer via ERLIN2-mediated stabilization and K63-dependent ubiquitination of Cyclin B1 Open
Potassium Calcium-Activated Channel Subfamily N1 (KCNN1), an integral membrane protein, is thought to regulate neuronal excitability by contributing to the slow component of synaptic after hyperpolarization. However, the role of KCNN1 in t…
View article: FGL1-LAG3 axis impairs IL-10-Producing regulatory T cells associated with Systemic lupus erythematosus disease activity
FGL1-LAG3 axis impairs IL-10-Producing regulatory T cells associated with Systemic lupus erythematosus disease activity Open
The FGL1-LAG3 signal axis is a key mechanism that subverts the suppressive function of Treg cells. This may provide a new therapeutic target for SLE and SLE-induced liver damage.
View article: A functional MMP-9-1562C>T polymorphism, MMP-9 serum levels and nephrolithiasis risk in a southern Chinese population
A functional MMP-9-1562C>T polymorphism, MMP-9 serum levels and nephrolithiasis risk in a southern Chinese population Open
Background The role of matrix metalloproteinase 9 (MMP-9) in the pathophysiology of chronic kidney disease (CKD), which is associated with a nearly two-fold greater risk for urinary calculi compared to people without CKD, has been demonstr…
View article: The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment
The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment Open
Formaldehyde (FA) has been found to induce major Alzheimer’s disease (AD)-like features including cognitive impairment, Aβ deposition, and Tau hyperphosphorylation, suggesting that it may play a significant role in the initiation and progr…
View article: The altered composition of gut microbiota and biochemical features as well as dietary patterns in southern Chinese population with recurrent renal calcium oxalate stone
The altered composition of gut microbiota and biochemical features as well as dietary patterns in southern Chinese population with recurrent renal calcium oxalate stone Open
The correlation between gut microbiota, biochemical features and dietary patterns in recurrent stone formers have been limited investigated in Chinese population.42 patients with calcium oxalate stone (CaOxS group), including 34 recurrent …
View article: Reduced levels of N6-methyladenosine in RNA of peripheral blood mononuclear cells from patients with Alzheimer's disease
Reduced levels of N6-methyladenosine in RNA of peripheral blood mononuclear cells from patients with Alzheimer's disease Open
Background Alzheimer's disease (AD) is the leading cause of dementia, yet its underlying causes remain unknown. Increasing evidence supports a role for epigenetic modifications in AD pathogenesis. N6-methyladenosine (m6A), the most common …
View article: SARS-CoV-2 epitope-specific T cells: Immunity response feature, TCR repertoire characteristics and cross-reactivity
SARS-CoV-2 epitope-specific T cells: Immunity response feature, TCR repertoire characteristics and cross-reactivity Open
The devastating COVID-19 pandemic caused by SARS-CoV-2 and multiple variants or subvariants remains an ongoing global challenge. SARS-CoV-2-specific T cell responses play a critical role in early virus clearance, disease severity control, …
View article: LncRNA T376626 is a promising serum biomarker and promotes proliferation, migration, and invasion via binding to LAMC2 in triple-negative breast cancer
LncRNA T376626 is a promising serum biomarker and promotes proliferation, migration, and invasion via binding to LAMC2 in triple-negative breast cancer Open
LncRNA T376626 may serve as a TNBC serum-based diagnostic and prognostic biomarker and play an oncogenic role in TNBC progression through binding to LAMC2.
View article: CYP2C19-rs4986893 confers risk to major depressive disorder and bipolar disorder in the Han Chinese population whereas ABCB1-rs1045642 acts as a protective factor
CYP2C19-rs4986893 confers risk to major depressive disorder and bipolar disorder in the Han Chinese population whereas ABCB1-rs1045642 acts as a protective factor Open
Background Genetic risks may predispose individuals to major mood disorders differently. This study investigated the gene polymorphisms of previously reported candidate genes for major depressive disorder (MDD) and bipolar disorder (BPD) i…
View article: Babao Dan Alleviates Cancer Cachexia in Mice Via Inhibiting IL-6/STAT3 Signaling Pathway
Babao Dan Alleviates Cancer Cachexia in Mice Via Inhibiting IL-6/STAT3 Signaling Pathway Open
Background: Cancer cachexia is a common but severe condition that causes muscle wasting, body weight loss, and progressive functional impairment, affecting over 50% of cancer patients. Currently, there are no effective treatments that can …
View article: The potential diagnostic accuracy of urine formaldehyde levels in Alzheimer’s disease: A systematic review and meta-analysis
The potential diagnostic accuracy of urine formaldehyde levels in Alzheimer’s disease: A systematic review and meta-analysis Open
Background Formaldehyde (FA), a toxic aldehyde, has been shown to be associated with a variety of cognitive disorders, including Alzheimer’s disease (AD). There is increasing evidence that FA levels are significantly increased in AD patien…