Qiang Pu
YOU?
Author Swipe
View article: Integrative analysis of non-small cell lung cancer identifies Jumonji domain-containing 6/ETS homologous factor axis as a target to overcome radioresistance
Integrative analysis of non-small cell lung cancer identifies Jumonji domain-containing 6/ETS homologous factor axis as a target to overcome radioresistance Open
Radiation therapy (RT) is a key treatment strategy for lung cancer, yet its efficacy is frequently compromised by radioresistance. The combination of RT with targeted therapies enhances treatment outcomes for non-small cell lung cancer (NS…
View article: A novel approach to extract thoracic cavity specimens using surgical gloves in video-assisted thoracic surgery
A novel approach to extract thoracic cavity specimens using surgical gloves in video-assisted thoracic surgery Open
View article: Strain-Softening-Based Elliptical Wellbore Model for Horizontal In-Situ Stress Prediction and Wellbore Stability Analysis in the Wujiaping Formation of Kaijiang-Liangping Block, Eastern Sichuan Basin, Sichuan Province
Strain-Softening-Based Elliptical Wellbore Model for Horizontal In-Situ Stress Prediction and Wellbore Stability Analysis in the Wujiaping Formation of Kaijiang-Liangping Block, Eastern Sichuan Basin, Sichuan Province Open
Marine shale is highly prone to wellbore collapse due to its high pore pressure, propensity for hydration and swelling, distinct bedding planes, and low tensile strength. Horizontal in situ stress serves as a critical parameter for wellbor…
View article: Methane Cycling Microbes are Important Predictors of Methylmercury Accumulation in Rice Paddies
Methane Cycling Microbes are Important Predictors of Methylmercury Accumulation in Rice Paddies Open
Microbial production of methylmercury from inorganic mercury in rice paddies poses health risks to consumers of this essential dietary staple. Although mercury-methylating communities are well characterized, the microbial guilds contributi…
View article: The Prognostic Value of Nutritional and Immune Indices for Stage <scp>IB</scp> Non‐Small Cell Lung Cancer Patients: Insights From a Retrospective Cohort Study
The Prognostic Value of Nutritional and Immune Indices for Stage <span>IB</span> Non‐Small Cell Lung Cancer Patients: Insights From a Retrospective Cohort Study Open
Background Postoperative recurrence is a critical factor affecting the prognosis of stage IB non‐small cell lung cancer (NSCLC). We aimed to evaluate the prognostic value of Nutritional and Immune Indices (NII) for postoperative recurrence…
View article: SLC34A2 inhibits tumorigenesis and progression via upregulating LRRK2/TTF-1/SELENBP1 axis in lung adenocarcinoma
SLC34A2 inhibits tumorigenesis and progression via upregulating LRRK2/TTF-1/SELENBP1 axis in lung adenocarcinoma Open
Alveolar type II epithelial (AT2) cells have the properties of stem cells, abnormal AT2 cells serve as one of the original cells in lung adenocarcinoma (LUAD). However, the abnormal genes expression of AT2 cells during their malignant tran…
View article: Expert Consensus on Subxiphoid and Subcostal Arch Thoracoscopic Resection for the Treatment of Thymoma
Expert Consensus on Subxiphoid and Subcostal Arch Thoracoscopic Resection for the Treatment of Thymoma Open
Surgery is the primary treatment for thymoma. Although subxiphoid and subcostal arch thoracoscopic thymoma surgery is widely used, there is currently a lack of consensus regarding its use, nor have standards been established. Based on the …
View article: Surgical treatment of small-cell lung cancer: long-term prognosis and patterns of adjuvant therapy
Surgical treatment of small-cell lung cancer: long-term prognosis and patterns of adjuvant therapy Open
Surgical intervention combined with perioperative adjuvant therapy provides significant survival benefits for patients with SCLC. Notably, preoperative neoadjuvant chemotherapy and postoperative adjuvant chemotherapy were associated with p…
View article: Multi-Omics Analysis of Chronic Heat Stress-Induced Biological Effects, Liver Injury, and Heat Tolerance Mechanisms via Oxidative and Anti-Inflammatory Pathways in Early-Pregnancy Sows
Multi-Omics Analysis of Chronic Heat Stress-Induced Biological Effects, Liver Injury, and Heat Tolerance Mechanisms via Oxidative and Anti-Inflammatory Pathways in Early-Pregnancy Sows Open
The prenatal environment critically influences sow and offspring health, with the liver being highly susceptible to heat stress (HS) and vital for antioxidant defense. However, mechanisms underlying HS impacts on early pregnancy and hepati…
View article: Past, present, and future of exosomes research in cancer: A bibliometric and visualization analysis
Past, present, and future of exosomes research in cancer: A bibliometric and visualization analysis Open
Cancer seriously threatens the lives and health of people worldwide, and exosomes seem to play an important role in managing cancer effectively, which has attracted extensive attention from researchers in recent years. This study aimed to …
View article: Expert Consensus on Perioperative Physician–Pharmacist Airway Co‐Management
Expert Consensus on Perioperative Physician–Pharmacist Airway Co‐Management Open
Background Airway management during the perioperative period is a vital component of perioperative care. However, there is a lack of consensus on the selection of medications, timing of administration, and the management of airway complica…
View article: Joint association of depressive symptoms and dietary patterns with mortality among US cancer survivors: a population-based study
Joint association of depressive symptoms and dietary patterns with mortality among US cancer survivors: a population-based study Open
The joints of depressive symptoms and certain dietary patterns were associated with risks of all-cause, cancer-specific, and noncancer mortality among cancer survivors. Early psychological counseling and individualized dietary strategies a…
View article: Dissolved organic matter fosters core mercury-methylating microbiomes for methylmercury production in paddy soils
Dissolved organic matter fosters core mercury-methylating microbiomes for methylmercury production in paddy soils Open
Methylmercury (MeHg), accumulated in rice grains, is highly toxic for humans. Its production is largely driven by microbial methylation in paddy soils; however, dissolved organic matter (DOM) is a critical component of the soil biogeochemi…
View article: Accuracy of Large Language Models for Literature Screening in Thoracic Surgery: Diagnostic Study
Accuracy of Large Language Models for Literature Screening in Thoracic Surgery: Diagnostic Study Open
Background Systematic reviews and meta-analyses rely on labor-intensive literature screening. While machine learning offers potential automation, its accuracy remains suboptimal. This raises the question of whether emerging large language …
View article: Global Trends of Early, Middle, and Late‐Onset Lung Cancer From 1990 to 2021: Results From the Global Burden of Disease Study 2021
Global Trends of Early, Middle, and Late‐Onset Lung Cancer From 1990 to 2021: Results From the Global Burden of Disease Study 2021 Open
Background Although the global burden of lung cancer has generally declined in recent decades, the variation in onset age‐related trends remains insufficiently explored. In the current study, we aimed to systematically evaluate the most up…
View article: Propensity matching analysis of left upper tri-segmentectomy versus lobectomy for stage I non-small cell lung cancer
Propensity matching analysis of left upper tri-segmentectomy versus lobectomy for stage I non-small cell lung cancer Open
For stage I left upper NSCLC, LUTS, while preserving adequate surgical margins, achieves superior perioperative and comparable oncological outcomes to LUL.
View article: Prophylactic fiberoptic bronchoscopy after sleeve lobectomy can reduce the incidence of postoperative pneumonia: a propensity score matching study
Prophylactic fiberoptic bronchoscopy after sleeve lobectomy can reduce the incidence of postoperative pneumonia: a propensity score matching study Open
Prophylactic FOB after sleeve lobectomy was associated with improved postoperative outcomes and might be recommended for patients undergoing sleeve lobectomy.
View article: Validation of T stage classification strategy for >2 cm ground-glass opacity non-small cell lung cancer: a retrospective cohort study
Validation of T stage classification strategy for >2 cm ground-glass opacity non-small cell lung cancer: a retrospective cohort study Open
The T stage classification strategy proposed by ISALC remains applicable in patients with GGOs larger than 2 cm.
View article: CAdam: Confidence-Based Optimization for Online Learning
CAdam: Confidence-Based Optimization for Online Learning Open
Modern recommendation systems frequently employ online learning to dynamically update their models with freshly collected data. The most commonly used optimizer for updating neural networks in these contexts is the Adam optimizer, which in…
View article: Association of inflammatory cytokines with type 2 diabetes mellitus and diabetic nephropathy: a bidirectional Mendelian randomization study
Association of inflammatory cytokines with type 2 diabetes mellitus and diabetic nephropathy: a bidirectional Mendelian randomization study Open
Objective Previous observational studies have suggested associations between various inflammatory cytokines with type 2 diabetes mellitus and diabetic nephropathy. However, the causal association remains uncertain. Method Summary statistic…
View article: Recent Advances of Exosomes Derived from Skeletal Muscle and Crosstalk with Other Tissues
Recent Advances of Exosomes Derived from Skeletal Muscle and Crosstalk with Other Tissues Open
Skeletal muscle plays a crucial role in movement, metabolism, and energy homeostasis. As the most metabolically active endocrine organ in the body, it has recently attracted widespread attention. Skeletal muscle possesses the ability to re…
View article: Insights into sex differences in perioperative outcomes of non-small cell lung cancer patients
Insights into sex differences in perioperative outcomes of non-small cell lung cancer patients Open
Female NSCLC patients demonstrated lower incidence of complications, shorter postoperative length of stays, and less hospitalization cost after surgery. Those differences between men and women could be explained by their inherent biologica…
View article: Alveolar type 2 cells marker gene SFTPC inhibits epithelial-to-mesenchymal transition by upregulating SOX7 and suppressing WNT/β-catenin pathway in non-small cell lung cancer
Alveolar type 2 cells marker gene SFTPC inhibits epithelial-to-mesenchymal transition by upregulating SOX7 and suppressing WNT/β-catenin pathway in non-small cell lung cancer Open
Introduction Surfactant Protein C gene ( SFTPC ) is a marker gene of alveolar type 2 cells (AT2), which are the key structures of alveoli. Mutations or deletions in SFTPC cause idiopathic pulmonary fibrosis (IPF). Importantly, IPF is an in…
View article: Ten-year survival outcomes of video-assisted thoracic surgery vs. open major lung resection for stage I–III non-small cell lung cancer: a large cohort study in China
Ten-year survival outcomes of video-assisted thoracic surgery vs. open major lung resection for stage I–III non-small cell lung cancer: a large cohort study in China Open
Major lung resection via the VATS should be the preferred surgical option for stage I-III NSCLC patients due to its superior long-term survival outcome and advantages of less blood loss and shorter postoperative hospital stays.
View article: A case of bilateral lobar transplantation using a donor split right lung: A new idea of split lung transplantation
A case of bilateral lobar transplantation using a donor split right lung: A new idea of split lung transplantation Open
View article: Clinical characteristics and outcomes of lung transplantation in patients with severe COVID-19 infection: A systematic review and meta-analysis
Clinical characteristics and outcomes of lung transplantation in patients with severe COVID-19 infection: A systematic review and meta-analysis Open
For patients with COVID-19-associated ARDS or PF, LTx offers acceptable short-term outcomes and is suggested as a viable lifesaving treatment.
View article: Lymph node dissection of station 8 improves the survival of T≤3 cmN0M0 lung adenocarcinoma patients
Lymph node dissection of station 8 improves the survival of T≤3 cmN0M0 lung adenocarcinoma patients Open
8LND could improve the survival of T≤3 cmN0M0 lung adenocarcinoma patients. Routine 8LND is recommended, especially in male, smokers, patients with a pT2 tumor (≤3 cm), and patients with a poorly differentiated tumor.
View article: The prognostic value of visceral pleural infiltration in ≤3 cm nonsmall cell lung cancer presenting with ground glass opacity: an inverse probability of treatment weighting study
The prognostic value of visceral pleural infiltration in ≤3 cm nonsmall cell lung cancer presenting with ground glass opacity: an inverse probability of treatment weighting study Open
Background: Visceral pleural infiltration (VPI) has been identified as an important risk factor in nonsmall cell lung cancer (NSCLC) for many decades. However, for patients who present with ground glass opacity (GGO), the prognostic value …
View article: Dissolved organic matter fosters core mercury-methylating microbiome for methylmercury production in paddy soils
Dissolved organic matter fosters core mercury-methylating microbiome for methylmercury production in paddy soils Open
Methylmercury (MeHg), accumulated in rice grain, is highly toxic for human. Its production is largely driven by microbial methylation in paddy soils; however, dissolved organic matter (DOM) represents a hotspot for soil biogeochemistry, re…
View article: Supplementary material to "Dissolved organic matter fosters core mercury-methylating microbiome for methylmercury production in paddy soils"
Supplementary material to "Dissolved organic matter fosters core mercury-methylating microbiome for methylmercury production in paddy soils" Open
Correspondence to: Bo Meng (