Quan Zhou
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View article: A comparative study of the efficacy of whether or not to preserve the joint capsule during PLIF surgery in patients with isthmic spondylolisthesis
A comparative study of the efficacy of whether or not to preserve the joint capsule during PLIF surgery in patients with isthmic spondylolisthesis Open
Purpose The purpose of this study is to investigate the effect of joint capsule preservation during posterior lumbar interbody fusion (PLIF) on postoperative low back pain and long-term adjacent segment stability in isthmic spondylolisthes…
View article: Do orthopedic surgeons pay sufficient attention to osteoporosis in elderly patients with hip fragility fractures? A retrospective cohort study of a tertiary general hospital in China
Do orthopedic surgeons pay sufficient attention to osteoporosis in elderly patients with hip fragility fractures? A retrospective cohort study of a tertiary general hospital in China Open
Summary: Timely management of osteoporosis is vitally important for elderly patients with hip fragility fractures. Our study revealed age-related enhancements in diagnostic and therapeutic rates in this population, with notable improvement…
View article: Impact of Sagittal Spinal Balance on Functional Recovery After <scp>PLIF</scp> of <scp>L5</scp>‐<scp>S1</scp> Isthmic Spondylolisthesis With Lumbar Spinal Stenosis
Impact of Sagittal Spinal Balance on Functional Recovery After <span>PLIF</span> of <span>L5</span>‐<span>S1</span> Isthmic Spondylolisthesis With Lumbar Spinal Stenosis Open
Objective Despite the widespread use of posterior lumbar interbody fusion ( PLIF ) for L5 ‐ S1 isthmic spondylolisthesis ( IS ) with lumbar spinal stenosis ( LSS ), residual sagittal imbalance critically impairs long‐term pain relief and f…
View article: Impact of Paraspinal Sarcopenia on Clinical Outcomes in Intervertebral Disc Degeneration Patients Following Percutaneous Transforaminal Endoscopic Lumbar Discectomy
Impact of Paraspinal Sarcopenia on Clinical Outcomes in Intervertebral Disc Degeneration Patients Following Percutaneous Transforaminal Endoscopic Lumbar Discectomy Open
Objective The paraspinal muscles are a crucial component of the spine's extrinsic stabilization system. While the impact of paraspinal muscle sarcopenia on patient‐reported outcome measures (PROMs) after lumbar surgery is well known, its e…
View article: Prompt Update Algorithm Based on the Boolean Vector Inner Product and Ant Colony Algorithm for Fast Target Type Recognition
Prompt Update Algorithm Based on the Boolean Vector Inner Product and Ant Colony Algorithm for Fast Target Type Recognition Open
In recent years, data mining technology has become increasingly popular, evolving into an independent discipline as research deepens. This study constructs and optimizes an association rule algorithm based on the Boolean vector (BV) inner …
View article: Selenium nanoparticles ameliorate lumbar disc degeneration by restoring GPX1-mediated redox homeostasis and mitochondrial function of nucleus pulposus cells
Selenium nanoparticles ameliorate lumbar disc degeneration by restoring GPX1-mediated redox homeostasis and mitochondrial function of nucleus pulposus cells Open
Intervertebral disc degeneration (IVDD) is a prevalent musculoskeletal disorder that involves the excessive accumulation of reactive oxygen species (ROS), resulting in mitochondrial dysfunction and matrix metabolism imbalance in nucleus pu…
View article: Selenium nanoparticles ameliorate lumbar disc degeneration by restoring GPX1-mediated redox homeostasis and mitochondrial function of nucleus pulposus cells
Selenium nanoparticles ameliorate lumbar disc degeneration by restoring GPX1-mediated redox homeostasis and mitochondrial function of nucleus pulposus cells Open
Intervertebral disc degeneration (IVDD) is a prevalent musculoskeletal disorder that involves the excessive accumulation of reactive oxygen species (ROS), resulting in mitochondrial dysfunction and matrix metabolism imbalance in nucleus pu…
View article: Melatonin-encapsuled silk fibroin electrospun nanofibers promote vascularized bone regeneration through regulation of osteogenesis-angiogenesis coupling
Melatonin-encapsuled silk fibroin electrospun nanofibers promote vascularized bone regeneration through regulation of osteogenesis-angiogenesis coupling Open
The repair of critical-sized bone defects poses a significant challenge due to the absence of periosteum, which plays a crucial role in coordinating the processes of osteogenesis and vascularization during bone healing. Herein, we hypothes…
View article: Effects of Percutaneous Kyphoplasty for the Treatment of Thoracic Osteoporotic Vertebral Compression Fractures with or without Intravertebral Cleft in Elderly Patients
Effects of Percutaneous Kyphoplasty for the Treatment of Thoracic Osteoporotic Vertebral Compression Fractures with or without Intravertebral Cleft in Elderly Patients Open
PKP is an adoptable measure to treat thoracic OVCFs with or without IVC. Our study revealed that the NIVC group was superior to the IVC group in terms of improved vertebral height and pain recovery at long-term follow-up (3 years).
View article: Melatonin rescues the mitochondrial function of bone marrow‐derived mesenchymal stem cells and improves the repair of osteoporotic bone defect in ovariectomized rats
Melatonin rescues the mitochondrial function of bone marrow‐derived mesenchymal stem cells and improves the repair of osteoporotic bone defect in ovariectomized rats Open
Osteoporotic bone defects, a severe complication of osteoporosis, are distinguished by a delayed bone healing process and poor repair quality. While bone marrow‐derived mesenchymal stem cells (BMMSCs) are the primary origin of bone‐forming…
View article: Benefits of Early Surgical Treatment for Patients with Multilevel Cervical Canal Stenosis of Acute Traumatic Central Cord Syndrome
Benefits of Early Surgical Treatment for Patients with Multilevel Cervical Canal Stenosis of Acute Traumatic Central Cord Syndrome Open
Introduction Currently, there exists considerable debate surrounding the optimal treatment approaches for different subtypes of patients with spinal cord injury (SCI). The purpose of this study was to conduct a comparative analysis of the …
View article: Effects of distribution of bone cement on clinical efficacy and secondary fracture after percutaneous kyphoplasty for osteoporotic vertebral compression fractures
Effects of distribution of bone cement on clinical efficacy and secondary fracture after percutaneous kyphoplasty for osteoporotic vertebral compression fractures Open
Objective To investigate the effect of bilateral bone cement distribution on the clinical efficacy of percutaneous kyphoplasty (PKP) in the treatment of osteoporotic vertebral compression fracture (OVCF). Methods According to strict inclus…
View article: Selenium-modified bone cement promotes osteoporotic bone defect repair in ovariectomized rats by restoring GPx1-mediated mitochondrial antioxidant functions
Selenium-modified bone cement promotes osteoporotic bone defect repair in ovariectomized rats by restoring GPx1-mediated mitochondrial antioxidant functions Open
Over-accumulation of reactive oxygen species (ROS) causes mitochondrial dysfunction and impairs the osteogenic potential of bone marrow-derived mesenchymal stem cells (BMMSCs). Selenium (Se) protects BMMSCs from oxidative stress-induced da…
View article: Changes in the gut microbiota of osteoporosis patients based on 16S rRNA gene sequencing: a systematic review and meta-analysis
Changes in the gut microbiota of osteoporosis patients based on 16S rRNA gene sequencing: a systematic review and meta-analysis Open
BACKGROUND: Osteoporosis (OP) has become a major public health issue, threatening the bone health of middle-aged and elderly people from all around the world. Changes in the gut microbiota (GM) are correlated with the maintenance of bone m…
View article: Effect of the intermediate pedicle screws and their insertion depth on sagittal balance and functional outcomes of lumbar fracture
Effect of the intermediate pedicle screws and their insertion depth on sagittal balance and functional outcomes of lumbar fracture Open
Objective This study aimed to examine the effect of the intermediate pedicle screws and their insertion depth on sagittal balance and functional outcomes of lumbar fracture. Methods This study reviewed 1,123 patients with lumbar fractures …
View article: A continuum structural topology optimization method considering frequency constraints and the effect of self-weight
A continuum structural topology optimization method considering frequency constraints and the effect of self-weight Open
This work proposes a method for optimizing the continuum structural topology under multiple load cases considering frequency constraints and the effect of self-weight. An improved Solid Isotropic Material with Penalization (SIMP) model is …
View article: Poly(ε-caprolactone)-based nanofibrous scaffold incorporated with decellularized bone extracellular matrix as a potential strategy for bone regeneration
Poly(ε-caprolactone)-based nanofibrous scaffold incorporated with decellularized bone extracellular matrix as a potential strategy for bone regeneration Open
Background: Critical size bone defect is still a great challenge in orthopedics. Scaffolds with nanofibrous microstructure seems a promising candidate for critical size bone defect repair. Here we fabricated poly(ε-caprolactone)-based nano…
View article: Comparison of Efficacy of Percutaneous Vertebroplasty versus Percutaneous Kyphoplasty in the Treatment of Osteoporotic Vertebral Asymmetric Compression Fracture
Comparison of Efficacy of Percutaneous Vertebroplasty versus Percutaneous Kyphoplasty in the Treatment of Osteoporotic Vertebral Asymmetric Compression Fracture Open
In our study, PVP and PKP are both effective in the treatment of OVACF, but PKP surgery had better long-term clinical efficacy.
View article: Kyphoplasty for thoracic and lumbar fractures with an intravertebral vacuum phenomenon in ankylosing spondylitis patients
Kyphoplasty for thoracic and lumbar fractures with an intravertebral vacuum phenomenon in ankylosing spondylitis patients Open
Background Intravertebral vacuum phenomenon (IVP) is a special sign after vertebral fractures, which is common in patients with ankylosing spondylitis (AS) and may indicate pseudarthrosis and bone nonunion that lead to spinal instability. …
View article: Percutaneous Kyphoplasty in Patients with Severe Osteoporotic Vertebral Compression Fracture with and without Intravertebral Cleft: A Retrospective Comparative Study
Percutaneous Kyphoplasty in Patients with Severe Osteoporotic Vertebral Compression Fracture with and without Intravertebral Cleft: A Retrospective Comparative Study Open
PKP can give satisfactory outcomes for the treatment of sOVCF with or without IVC. However, the NIVC group showed better clinical outcomes and could maintain spinal sagittal balance better than the IVC group during long-term follow-up.
View article: Clinical analysis of osteoporotic vertebral oblique compression fracture treated with bone cement combined with balloon
Clinical analysis of osteoporotic vertebral oblique compression fracture treated with bone cement combined with balloon Open
Objective： To explore the clinical effect of bone cement combined with balloon expansion in the treatment of osteoporotic vertebral oblique compression fracture. Methods： This study retrospectively reviewed the patients who were diagnosed …
View article: Clinical analysis of osteoporotic vertebral oblique compression fracture treated with bone cement combined with balloon
Clinical analysis of osteoporotic vertebral oblique compression fracture treated with bone cement combined with balloon Open
ObjectiveTo explore the clinical effect of bone cement combined with balloon expansion in the treatment of osteoporotic vertebral oblique compression fracture. MethodsThis study retrospectively reviewed the patients who were diagnosed with…
View article: Application of 3-dimensional printing guide template and pointed lotus-style regulator in percutaneous pedicle screw fixation for thoracolumbar fractures
Application of 3-dimensional printing guide template and pointed lotus-style regulator in percutaneous pedicle screw fixation for thoracolumbar fractures Open
This study aims to analysis the efficacy of the 3D printing percutaneous guide template in combination with the pointed lotus-style regulator in percutaneous pedicle screw fixation. 60 thoracolumbar fractures patients receiving percutaneou…
View article: Comparison of Percutaneous Kyphoplasty With or Without Posterior Pedicle Screw Fixation on Spinal Sagittal Balance in Elderly Patients With Severe Osteoporotic Vertebral Compression Fracture: A Retrospective Study
Comparison of Percutaneous Kyphoplasty With or Without Posterior Pedicle Screw Fixation on Spinal Sagittal Balance in Elderly Patients With Severe Osteoporotic Vertebral Compression Fracture: A Retrospective Study Open
Objective To compare the effects of percutaneous kyphoplasty (PKP) with or without posterior pedicle screw fixation (PPSF) on spinal sagittal balance in elderly patients with severe osteoporotic vertebral compression fracture (sOVCF). Meth…
View article: Comparison of Anterior and Posterior Approaches for Acute Traumatic Central Spinal Cord Syndrome with Multilevel Cervical Canal Stenosis without Cervical Fracture or Dislocation
Comparison of Anterior and Posterior Approaches for Acute Traumatic Central Spinal Cord Syndrome with Multilevel Cervical Canal Stenosis without Cervical Fracture or Dislocation Open
Introduction . This is a retrospective comparative study that aims to compare the benefits of different surgical approaches for patients with multilevel cervical canal stenosis (CCS) without cervical fracture or dislocation of acute trauma…
View article: Effect of Different Anesthesia and Puncture Methods of Percutaneous Kyphoplasty on More Than 90‐Year‐Old Osteoporotic Vertebral Fracture: Advantages of the ERAS Concept
Effect of Different Anesthesia and Puncture Methods of Percutaneous Kyphoplasty on More Than 90‐Year‐Old Osteoporotic Vertebral Fracture: Advantages of the ERAS Concept Open
Background . Percutaneous kyphoplasty (PKP) is an effective minimally invasive technique for the treatment of osteoporotic vertebral fracture (OVF) in recent years. This study focuses on the analysis of PKP surgery and anesthesia in osteop…