Ying Liu
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View article: Opening the black box: defining true-negative outcomes in esophageal cancer screening — a population-based study
Opening the black box: defining true-negative outcomes in esophageal cancer screening — a population-based study Open
Individuals with normal Lugol staining should be considered the genuinely screening-negative population for esophageal cancer. A 10-year screening interval is recommended for normal-stained individuals, while 2-3 years are necessary for ND…
View article: From dry eye to depression: a machine learning-based framework for predicting adolescent mental health
From dry eye to depression: a machine learning-based framework for predicting adolescent mental health Open
Integrating ocular health with psychosocial factors enhances machine-learning prediction of adolescent depression and may support earlier, school-based identification and referral. Given the low-cost, questionnaire-based inputs and favorab…
View article: Case report: First report of metastatic esophageal squamous cell carcinoma with EGFR p.S768I mutation: remarkable response to third-generation EGFR-TKI
Case report: First report of metastatic esophageal squamous cell carcinoma with EGFR p.S768I mutation: remarkable response to third-generation EGFR-TKI Open
View article: Correction: Eco-friendly synthesis of reduced graphene oxide/palladium composite and its catalytic, antibacterial and antifungal activities for bone regeneration and fracture treatment
Correction: Eco-friendly synthesis of reduced graphene oxide/palladium composite and its catalytic, antibacterial and antifungal activities for bone regeneration and fracture treatment Open
View article: A correlation study on triglyceride-glucose index and extensive neovascularization within carotid artery plaques
A correlation study on triglyceride-glucose index and extensive neovascularization within carotid artery plaques Open
This study demonstrates that the TyG index is significantly and independently associated with extensive IPN in carotid plaques. This finding suggests the TyG index has potential as a supplementary serological marker in the assessment of pl…
View article: Glycerol‐Mediated Freeze‐Thaw Stabilization of Probiotic‐Loaded High Internal Phase Emulsions
Glycerol‐Mediated Freeze‐Thaw Stabilization of Probiotic‐Loaded High Internal Phase Emulsions Open
This study developed high internal phase emulsions (HIPEs) using glycerol to partially replace water, aiming to enhance freeze‐thaw stability for Lactiplantibacillus plantarum P9 (P9). Soy protein isolate was employed as the emulsifier to …
View article: Intracranial infection caused by Mycoplasma hominis after neurosurgical operation: an easily overlooked but serious condition
Intracranial infection caused by Mycoplasma hominis after neurosurgical operation: an easily overlooked but serious condition Open
Introduction: Mycoplasma hominis (M. hominis) is a commensal that mainly colonizes in the microflora of the genitourinary tracts and is associated with urogenital tract infections. There are reports of central nervous system (CNS) infectio…
View article: Low-dose rituximab in lupus enteritis: a comparative study on its efficacy in modulating mucosal immunity and reducing inflammation
Low-dose rituximab in lupus enteritis: a comparative study on its efficacy in modulating mucosal immunity and reducing inflammation Open
Both RTX plus glucocorticoids and conventional immunosuppressants plus glucocorticoids are effective in inducing clinical and radiologic remission in LE. RTX may lead to faster improvement in certain serologic and inflammatory biomarkers. …
View article: Corrigendum to “Quantification of tumor heterogeneity based on fractal dimension for predicting the response to neoadjuvant chemotherapy in triple-negative breast cancer”. [Eur. J. Radiol. 192 (2025) 112413]
Corrigendum to “Quantification of tumor heterogeneity based on fractal dimension for predicting the response to neoadjuvant chemotherapy in triple-negative breast cancer”. [Eur. J. Radiol. 192 (2025) 112413] Open
View article: Utilizing atomic-scale grain boundary segregation: a new way for constructing the lamellar heterogeneous magnesium alloy
Utilizing atomic-scale grain boundary segregation: a new way for constructing the lamellar heterogeneous magnesium alloy Open
Heterogeneous structure significantly impacts the applications of wrought magnesium (Mg) alloys. Herein, we put forward a novel idea for constructing the heterogeneous structure by utilizing solute grain boundary (GB) segregation on recrys…
View article: Neutrophil extracellular traps in ischemic stroke: mechanisms, clinical implications, and therapeutic potential
Neutrophil extracellular traps in ischemic stroke: mechanisms, clinical implications, and therapeutic potential Open
Ischemic stroke remains a leading cause of mortality and disability, with many patients failing to benefit from reperfusion therapies due to lysis-resistant thrombus formation and severe neuroinflammation. This highlights an urgent need to…
View article: Revealing the Influence of Zn Content on the Microstructure and Mechanical Properties of Bimodal Mg-Zn-Gd-Sm Alloy
Revealing the Influence of Zn Content on the Microstructure and Mechanical Properties of Bimodal Mg-Zn-Gd-Sm Alloy Open
The development of low-cost and high-performance Mg alloys is an important way to achieve further application of magnesium alloys. In this work, the as-extruded Mg98.3−xZnxGd1Sm0.7 alloy with excellent mechanical properties is successfully…
View article: Distribution for platelet antibody in patients with immune-mediated platelet transfusion refractoriness
Distribution for platelet antibody in patients with immune-mediated platelet transfusion refractoriness Open
This study clarified platelet antibody distribution in Chinese iPTR patients. Besides HLA Class I antibodies, autoantibodies against platelet glycoproteins play a key role. Among HPA antibodies, HPA-5b may predominate in the Chinese popula…
View article: Quantitative study of vestibular endolymphatic hydrops in Meniere’s disease based on Three-Dimensional real Inversion Recovery (3D-real IR) sequence
Quantitative study of vestibular endolymphatic hydrops in Meniere’s disease based on Three-Dimensional real Inversion Recovery (3D-real IR) sequence Open
3D-real IR MRI enables quantitative EH assessment, with ELR thresholds providing objective grading criteria. EH severity reflects pathophysiological progression through its associations with auditory/vestibular dysfunction and disease stag…
View article: STAT5B REGULATES SEXUAL DIMORPHISM IN HEPATIC GLUCOSE METABOLISM IN ZEBRAFISH
STAT5B REGULATES SEXUAL DIMORPHISM IN HEPATIC GLUCOSE METABOLISM IN ZEBRAFISH Open
View article: FGFR1-amplified colorectal cancer: a distinct prognostic subtype identified through integrated genomic and immunohistochemical profiling
FGFR1-amplified colorectal cancer: a distinct prognostic subtype identified through integrated genomic and immunohistochemical profiling Open
View article: Glycosylated extracellular matrix drives immune suppression by controlling T cell movement, macrophage phenotype, and macrophage-T cell crosstalk in triple negative breast cancer
Glycosylated extracellular matrix drives immune suppression by controlling T cell movement, macrophage phenotype, and macrophage-T cell crosstalk in triple negative breast cancer Open
The tumor extracellular matrix (ECM) is increasingly recognized as a key driver of immune suppression and therapy resistance in cancer. However, the specific ECM components and mechanisms that create this immunosuppressive environment rema…
View article: End-to-end deep learning for the diagnosis of pelvic and sacral tumors using non-enhanced MRI: a multi-center study
End-to-end deep learning for the diagnosis of pelvic and sacral tumors using non-enhanced MRI: a multi-center study Open
View article: The “Clover” solution – 4-lumen double-loop stoma in managing multifocal intestinal obstruction due to peritoneal metastases
The “Clover” solution – 4-lumen double-loop stoma in managing multifocal intestinal obstruction due to peritoneal metastases Open
Multifocal intestinal obstruction (IO) due to peritoneal metastases (PM) presents significant surgical challenges, with traditional approaches often falling short. The Clover stoma, a four-lumen technique, combines a loop ileostomy and tra…
View article: Isoquercitrin mitigates intestinal ischemia-reperfusion injury by regulating intestinal flora and inhibiting NLRP3 inflammasome activation
Isoquercitrin mitigates intestinal ischemia-reperfusion injury by regulating intestinal flora and inhibiting NLRP3 inflammasome activation Open
View article: Induction of Autophagy as a Therapeutic Breakthrough for NAFLD: Current Evidence and Perspectives
Induction of Autophagy as a Therapeutic Breakthrough for NAFLD: Current Evidence and Perspectives Open
Nonalcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome characterised by hepatic steatosis in the absence of significant alcohol consumption or other specific causes of liver injury. It has become one of the leading caus…
View article: Therapeutic potential of mesenchymal stem cell exosomes for tumors in the digestive system: From bench to bedside
Therapeutic potential of mesenchymal stem cell exosomes for tumors in the digestive system: From bench to bedside Open
Exosomes are small, bilayer lipid vesicles with diameters ranging from approximately 40–160 nm. These vesicles carry a diverse array of molecular cargo, including DNA, RNA, lipids, and proteins, which play a critical role in intercel…
View article: Imaging features and prognostic significance of immune checkpoint inhibitor–related pneumonitis in NSCLC
Imaging features and prognostic significance of immune checkpoint inhibitor–related pneumonitis in NSCLC Open
CIP without improvement or resolution, a high percentage of neutrophils and elevated albumin level of peripheral blood examination were independent predictors for the prognosis of NSCLC patients, which may have an implication for treatment.
View article: Study on the Adsorption Behavior of a Cellulose Nanofibril/Tannic Acid/Polyvinyl Alcohol Aerogel for Cu(II), Cd(II), and Pb(II) Heavy Metal Ions
Study on the Adsorption Behavior of a Cellulose Nanofibril/Tannic Acid/Polyvinyl Alcohol Aerogel for Cu(II), Cd(II), and Pb(II) Heavy Metal Ions Open
Nanocellulose-based composite aerogels have the advantages of high porosity, biodegradability, and biocompatibility, with wide applications in many fields, such as adsorption, separation, energy storage, and heat insulation. In this study,…
View article: Exogenous adenosine counteracts tigecycline resistance in <i>tet</i> (X3)-harboring <i>Escherichia coli</i>
Exogenous adenosine counteracts tigecycline resistance in <i>tet</i> (X3)-harboring <i>Escherichia coli</i> Open
The rapid spread of antibiotic resistance poses a global health crisis. Tigecycline is a last-resort antibiotic, but the recent emergence of the plasmid-borne tet (X3) gene conferring high-level tigecycline resistance is deeply concerning.…
View article: 8-Epidiosbulbin E acetate triggers apoptosis via metabolic activation-mediated crosstalk between mitochondria and endoplasmic reticulum
8-Epidiosbulbin E acetate triggers apoptosis via metabolic activation-mediated crosstalk between mitochondria and endoplasmic reticulum Open
8-Epidiosbulbin E acetate (EEA), a furan-containing diterpenoid lactone and key component of Dioscorea bulbifera L., has been found to induce notable liver injury in mice through CYP3A-mediated metabolic activation to a cis-enedial reactiv…
View article: Nitrate protects against methotrexate-induced liver injury by activating Wnt/β-catenin Signaling in mice
Nitrate protects against methotrexate-induced liver injury by activating Wnt/β-catenin Signaling in mice Open
Methotrexate (MTX) is a drug used to treat autoimmune diseases and certain cancers. However, its untreatable hepatotoxic effect severely limits its clinical use. Therefore, further studies are required to combat MTX-induced liver injury. N…
View article: Moderate soil drying mitigates high temperature-induced spikelet opening impairment by enhancing jasmonates accumulation in lodicules of photo-thermosensitive male-sterile rice
Moderate soil drying mitigates high temperature-induced spikelet opening impairment by enhancing jasmonates accumulation in lodicules of photo-thermosensitive male-sterile rice Open
View article: Predictive nomogram for occult metastasis in central lymph nodes of papillary thyroid microcarcinoma based on clinical and ultrasound features
Predictive nomogram for occult metastasis in central lymph nodes of papillary thyroid microcarcinoma based on clinical and ultrasound features Open
The nomogram established in our study has a certain predictive ability for CLNM, which can be applied to the clinical management of cN0 PTMC patients, so as to provide more accurate preoperative evaluation and develop better treatment stra…
View article: Cellular imbalance in proximal and distal lung of CFTR−/− sheep in utero and at birth
Cellular imbalance in proximal and distal lung of CFTR−/− sheep in utero and at birth Open
Background The Lung is the major focus of therapeutic approaches for the inherited disorder cystic fibrosis (CF) as without treatment lung disease is life-limiting. However, the initiating events that predispose the CF lung to cycles of in…