Qingbo Zheng
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View article: The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track
The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track Open
The yak, an ideal model for studying high‐altitude hypoxia adaptation, possesses unique gastrointestinal tract (GIT) adaptability. However, understanding of cellular‐level mechanisms underlying host‐metabolite‐microbe within GIT that are c…
View article: Microbiota–Metabolite–Host Crosstalk Mediates the Impact of Dietary Energy Levels on Colonic Homeostasis in High-Altitude Ruminants
Microbiota–Metabolite–Host Crosstalk Mediates the Impact of Dietary Energy Levels on Colonic Homeostasis in High-Altitude Ruminants Open
The colon plays a crucial role in energy metabolism and intestinal health of ruminants during various physiological stages. Plateau ruminants have long been subjected to extreme environments characterized by hypoxia, cold, and nutritional …
View article: Whole-genome resequencing revealed the genetic diversity and body weight-related genes of Gannan yak
Whole-genome resequencing revealed the genetic diversity and body weight-related genes of Gannan yak Open
Body weight (BW) is a crucial indicator of animal growth and development, significantly influencing animal husbandry practices. Previous research has identified several genes associated with BW in certain yak breeds. However, the genetic b…
View article: Comparative analysis of growth patterns of Gannan Yak based on nonlinear models
Comparative analysis of growth patterns of Gannan Yak based on nonlinear models Open
Body weight and withers height are critical indicators of growth in animals, influencing husbandry practices. In this study, we measured the body weight and withers height of Gannan yaks at different ages (0, 6, 18, 30, 42, 54, 66, and 78 …
View article: Polarization-Analyzed Small-Angle Neutron Scattering with an $\textit{in-situ}$ $^{3}$He neutron spin filter at the China Spallation Neutron Source
Polarization-Analyzed Small-Angle Neutron Scattering with an $\textit{in-situ}$ $^{3}$He neutron spin filter at the China Spallation Neutron Source Open
Polarization-analyzed small-angle neutron scattering (PASANS) is an advanced technique that enables the selective investigation of magnetic scattering phenomena in magnetic materials and distinguishes coherent scattering obscured by incohe…
View article: Study on Single Nucleotide Polymorphism of LAP3 Gene and Its Correlation with Dairy Quality Traits of Gannan Yak
Study on Single Nucleotide Polymorphism of LAP3 Gene and Its Correlation with Dairy Quality Traits of Gannan Yak Open
This study explored the polymorphism of the leucine aminopeptidase (LAP3) gene and its relationship with milk quality characteristics in Gannan yak. A cohort of 162 Gannan yak was genotyped utilizing the Illumina Yak cGPS 7K BeadChip, and …
View article: Genetic structure analysis of yak breeds and their response to adaptive evolution
Genetic structure analysis of yak breeds and their response to adaptive evolution Open
Yaks are crucial genetic resources in the Tibetan Plateau and surrounding regions. Throughout the long process of domestication, natural and artificial selection pressures have enabled yaks to demonstrate adaptive characteristics to the en…
View article: The Idesia polycarpa genome provides insights into its evolution and oil biosynthesis
The Idesia polycarpa genome provides insights into its evolution and oil biosynthesis Open
View article: A comprehensive study on the longissius dorsi muscle of Ashdan yaks under different feeding regimes based on transcriptomic and metabolomic analyses
A comprehensive study on the longissius dorsi muscle of Ashdan yaks under different feeding regimes based on transcriptomic and metabolomic analyses Open
Yak is an important dominant livestock species at high altitude, and the growth performance of yak has obvious differences under different feeding methods. This experiment was conducted to compare the effects of different feeding practices…
View article: A comprehensive study on the longissius dorsi muscle of Ashdan yaks under different feeding regimes based on transcriptomic and metabolomic analyses
A comprehensive study on the longissius dorsi muscle of Ashdan yaks under different feeding regimes based on transcriptomic and metabolomic analyses Open
Yak is an important dominant livestock species at high altitude, and the growth performance of yak has obvious differences under different feeding methods. This experiment was conducted to compare the effects of different feeding practices…
View article: Interpretation of the Yak Skin Single-Cell Transcriptome Landscape
Interpretation of the Yak Skin Single-Cell Transcriptome Landscape Open
The morphogenesis of hair follicle structure is accompanied by the differentiation of skin tissue. Mammalian coats are produced by hair follicles. The formation of hair follicles requires signal transmission between the epidermis and dermi…
View article: The Novel Structural Variation in the GHR Gene Is Associated with Growth Traits in Yaks (Bos grunniens)
The Novel Structural Variation in the GHR Gene Is Associated with Growth Traits in Yaks (Bos grunniens) Open
The growth hormone receptor (GHR) is a member of the cytokine/hematopoietic factor receptor superfamily, which plays an important role in the growth and development, immunity, and metabolism of animals. This study identified a 246 bp delet…
View article: Correction: Construction of transcriptome atlas of white yak hair follicle during anagen and catagen using single-cell RNA sequencing
Correction: Construction of transcriptome atlas of white yak hair follicle during anagen and catagen using single-cell RNA sequencing Open
View article: Comparative Analysis of mRNA and miRNA Expression between Dermal Papilla Cells and Hair Matrix Cells of Hair Follicles in Yak
Comparative Analysis of mRNA and miRNA Expression between Dermal Papilla Cells and Hair Matrix Cells of Hair Follicles in Yak Open
The interaction between the dermal papilla cells (DPCs) and epidermal hair matrix cells (HMCs) of hair follicles (HFs) is crucial for the growth and development of HFs, but the molecular mechanism is complex and remains unclear. MicroRNAs …
View article: Construction of transcriptome atlas of white yak hair follicle during anagen and catagen using single-cell RNA sequencing
Construction of transcriptome atlas of white yak hair follicle during anagen and catagen using single-cell RNA sequencing Open
View article: Understanding Mammalian Hair Follicle Ecosystems by Single-Cell RNA Sequencing
Understanding Mammalian Hair Follicle Ecosystems by Single-Cell RNA Sequencing Open
Single-cell sequencing technology can fully reflect the heterogeneity of cell populations at the single cell level, making it possible for us to re-recognize various tissues and organs. At present, the sequencing study of hair follicles is…
View article: Bioinformatics analysis of KLK gene family in yak
Bioinformatics analysis of KLK gene family in yak Open
Kallikrein-related peptidases (KLK) have 15 members, which are the largest family of human serine proteases known so far, but there is no report about KLK in yak. In this study, Six members of yak KLK gene family were selected as the resea…
View article: Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple (Malus domestica)
Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple (Malus domestica) Open
γ-Aminobutyric Acid (GABA), a four-carbon non-protein amino acid, is a significant component of the free amino acid pool in most prokaryotic and eukaryotic organisms. GABA is involved in pH regulation, maintaining C/N balance, plant develo…
View article: An HD‐ZIP transcription factor, <i>MxHB13</i>, integrates auxin‐regulated and juvenility‐determined control of adventitious rooting in <i>Malus xiaojinensis</i>
An HD‐ZIP transcription factor, <i>MxHB13</i>, integrates auxin‐regulated and juvenility‐determined control of adventitious rooting in <i>Malus xiaojinensis</i> Open
Summary Adventitious root (AR) formation is a critical factor in the vegetative propagation of forestry and horticultural plants. Competence for AR formation declines in many species during the miR156/SPL‐mediated vegetative phase change. …
View article: MicroRNA156 (miR156) Negatively Impacts Mg-Protoporphyrin IX (Mg-Proto IX) Biosynthesis and Its Plastid-Nucleus Retrograde Signaling in Apple
MicroRNA156 (miR156) Negatively Impacts Mg-Protoporphyrin IX (Mg-Proto IX) Biosynthesis and Its Plastid-Nucleus Retrograde Signaling in Apple Open
Plastid-nucleus retrograde signaling (PNRS) play essential roles in regulating nuclear gene expression during plant growth and development. Excessive reactive oxygen species can trigger PNRS. We previously reported that in apple (Malus dom…
View article: MdGGT1 Impacts Apple miR156 Precursor Levels via Ontogenetic Changes in Subcellular Glutathione Homeostasis
MdGGT1 Impacts Apple miR156 Precursor Levels via Ontogenetic Changes in Subcellular Glutathione Homeostasis Open
- MdGGT1 affects thiol redox status and indirectly participates in the regulation of miR156 expression during vegetative phase change.