Qingfeng Lei
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View article: Certification of stroke centers at primary hospitals and the improvement of thrombolysis n South China during 2020–2022
Certification of stroke centers at primary hospitals and the improvement of thrombolysis n South China during 2020–2022 Open
Introduction: IVT use declined globally in 2020 due to the Corona Virus Disease 2019 (COVID-19) pandemic, but it increased in South China. This study was conducted to evaluate the association of establishing Stroke Prevention Centers (SPCs…
View article: Acoustic stimulation during sleep improves cognition and ameliorates Alzheimer's disease pathology in APP/PS1 mice
Acoustic stimulation during sleep improves cognition and ameliorates Alzheimer's disease pathology in APP/PS1 mice Open
Nonpharmacological therapies for Alzheimer's disease (AD) have become a popular research topic, and acoustic stimulation during sleep is one such promising strategy for the clinical treatment of AD. Some animal experiments have illustrated…
View article: Association between preoperative C-reactive protein to albumin ratio and late arteriovenous fistula dysfunction in hemodialysis patients: a cohort study
Association between preoperative C-reactive protein to albumin ratio and late arteriovenous fistula dysfunction in hemodialysis patients: a cohort study Open
Arteriovenous fistula (AVF) dysfunction is a critical complication in hemodialysis (HD) patients, with inflammation potentially contributing to its development. This retrospective cohort study aimed to investigate the association between p…
View article: Disease Detection and Identification of Rice Leaf Based on Improved Detection Transformer
Disease Detection and Identification of Rice Leaf Based on Improved Detection Transformer Open
In recent years, the domain of diagnosing plant afflictions has predominantly relied upon the utilization of deep learning techniques for classifying images of diseased specimens; however, these classification algorithms remain insufficien…
View article: Association between preoperative C-reactive protein to albumin ratio and late arteriovenous fistula dysfunction in hemodialysis patients: A cohort study
Association between preoperative C-reactive protein to albumin ratio and late arteriovenous fistula dysfunction in hemodialysis patients: A cohort study Open
Arteriovenous fistula (AVF) dysfunction in hemodialysis (HD) patients is linked to high mortality and inflammation may play a role. We investigated the association between CAR and AVF dysfunction in a group of HD patients from China. We co…
View article: Research on online test question recommendation technology based on multi-dimensional user dynamic portrait
Research on online test question recommendation technology based on multi-dimensional user dynamic portrait Open
This paper proposes a research method of personalized recommendation of test questions for users by fully collecting and studying the user’s characteristic data in multiple dimensions, establishing a dynamic user portrait, and mining and a…
View article: Acoustic Stimulation Improves Memory and Reverses the Contribution of Chronic Sleep Deprivation to Pathology in 3xTgAD Mice
Acoustic Stimulation Improves Memory and Reverses the Contribution of Chronic Sleep Deprivation to Pathology in 3xTgAD Mice Open
Objective: Acoustic stimulation during sleep is believed to enhance slow waves, which are critical to memory consolidation. However, clinical trials of acoustic stimulation have yielded mixed results concerning its effectiveness in improvi…
View article: Plasma Neurofilament Light Chain May Be a Biomarker for the Inverse Association Between Cancers and Neurodegenerative Diseases
Plasma Neurofilament Light Chain May Be a Biomarker for the Inverse Association Between Cancers and Neurodegenerative Diseases Open
An inverse association may exist between cancers and neurodegenerative diseases, although convenient biomarkers for verifying this inverse association are lacking. Plasma neurofilament light chain (NfL) is a novel biomarker for neurodegene…
View article: Ursolic Acid Attenuates Renal Injury Induced by Adriamycin in Mice
Ursolic Acid Attenuates Renal Injury Induced by Adriamycin in Mice Open
Objective: To explore the protective effects of ursolic acid (UA) on adriamycin nephropathy in mice. Methods: Totally 40 male Balb/c mice were randomly divided into normal group, model group, low dose of UA group and high dose of UA group.…
View article: Generation of an integration-free iPSC line(SYSUi001-A) from a sporadic Alzheimer's disease patient
Generation of an integration-free iPSC line(SYSUi001-A) from a sporadic Alzheimer's disease patient Open
Human iPSC line, iPSC-ADM01(SYSUi001-A), was generated from a 70-year-old male patient with sporadic Alzheimer's disease, using non-integrative reprogramming method. This cell line shows pluripotency both in vitro and in vivo, and has a no…
View article: Increased Risk of Post-Thrombolysis Intracranial Hemorrhage in Acute Ischemic Stroke Patients with Leukoaraiosis: A Meta-Analysis
Increased Risk of Post-Thrombolysis Intracranial Hemorrhage in Acute Ischemic Stroke Patients with Leukoaraiosis: A Meta-Analysis Open
The results of this meta-analysis show that leukoaraiosis approximately doubles the incidence of intracranial hemorrhage after thrombolytic therapy. However, it does not critically affect decision making regarding thrombolysis for patients…