Qingfeng Shang
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View article: FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma
FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma Open
Background Melanoma is a type of malignant tumor with high aggressiveness and poor prognosis. At present, metastasis of melanoma is still an important cause of death in melanoma patients. However, the potential functions and molecular mech…
View article: Additional file 1 of FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma
Additional file 1 of FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma Open
Additional file 1: Fig. S1. Verification of highly invasive HMY-1 cell sublines. a The growth pattern of HMY-1 and highly invasive HMY-1 cell sublines. b and c In vitro Transwell assay to verify the different metastatic potential between H…
View article: Additional file 2 of FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma
Additional file 2 of FMRP ligand circZNF609 destabilizes RAC1 mRNA to reduce metastasis in acral melanoma and cutaneous melanoma Open
Additional file 2: Table S1. The detailed information of human melanoma cell lines used in this study. Table S2. The sequences of primers and oligonucleotides used in this study. Table S3. circRNAs abundant in 3 cutaneous melanoma cell lin…
View article: The novel roles of circRNAs in human cancer
The novel roles of circRNAs in human cancer Open
Covalently closed single-stranded circular RNAs (circRNAs) consist of introns or exons and are widely present in eukaryotic cells. CircRNAs generally have low expression levels and relatively stable structures compared with messenger RNAs …