Qinghuan Yang
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View article: The impact of PANoptosis-related genes on immune profiles and subtype classification in ischemic stroke
The impact of PANoptosis-related genes on immune profiles and subtype classification in ischemic stroke Open
View article: Shh–S100A10 axis curbs neuronal PANoptosis after ischemic stroke
Shh–S100A10 axis curbs neuronal PANoptosis after ischemic stroke Open
Acute ischemic stroke is a highly prevalent and disabling disease with poor prognosis. Neuronal death is a major feature after a stroke. PANoptosis is a newly reported pattern of cell death, characterized by pyroptosis, apoptosis, and necr…
View article: The plasma lipopolysaccharide level is associated with contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction
The plasma lipopolysaccharide level is associated with contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction Open
View article: Vagus nerve stimulation inhibits pyroptosis and improves outcome of cerebral ischemic stroke by upregulating osteopontin (SPP1) to disturb ASC oligomerization
Vagus nerve stimulation inhibits pyroptosis and improves outcome of cerebral ischemic stroke by upregulating osteopontin (SPP1) to disturb ASC oligomerization Open
View article: Prognostic value of glycemic gap in ST-segment elevation myocardial infarction-associated acute kidney injury
Prognostic value of glycemic gap in ST-segment elevation myocardial infarction-associated acute kidney injury Open
Not applicable.
View article: Fibrotic scar formation after cerebral ischemic stroke: Targeting the Sonic hedgehog signaling pathway for scar reduction
Fibrotic scar formation after cerebral ischemic stroke: Targeting the Sonic hedgehog signaling pathway for scar reduction Open
JOURNAL/nrgr/04.03/01300535-202602000-00044/figure1/v/2025-05-17T081902Z/r/image-tiff Recent studies have shown that fibrotic scar formation following cerebral ischemic injury has varying effects depending on the microenvironment. However,…
View article: Inhibition of CK2 Diminishes Fibrotic Scar Formation and Improves Outcomes After Ischemic Stroke via Reducing BRD4 Phosphorylation
Inhibition of CK2 Diminishes Fibrotic Scar Formation and Improves Outcomes After Ischemic Stroke via Reducing BRD4 Phosphorylation Open
Fibrotic scars play important roles in tissue reconstruction and functional recovery in the late stage of nervous system injury. However, the mechanisms underlying fibrotic scar formation and regulation remain unclear. Casein kinase II (CK…
View article: New insights into Sirt1: potential therapeutic targets for the treatment of cerebral ischemic stroke
New insights into Sirt1: potential therapeutic targets for the treatment of cerebral ischemic stroke Open
Ischemic stroke is one of the main causes of mortality and disability worldwide. However, the majority of patients are currently unable to benefit from intravenous thrombolysis or intravascular mechanical thrombectomy due to the limited tr…
View article: M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats Open
In the central nervous system, the formation of fibrotic scar after injury inhibits axon regeneration and promotes repair. However, the mechanism underlying fibrotic scar formation and regulation remains poorly understood. M2 macrophages r…
View article: IL4-dependent M2 macrophage mediates fibrotic scar formation and functional restoration via Sonic Hedgehog/TGFβ1 axis in the early stage of cerebral ischemia in rats
IL4-dependent M2 macrophage mediates fibrotic scar formation and functional restoration via Sonic Hedgehog/TGFβ1 axis in the early stage of cerebral ischemia in rats Open
Background: Fibrotic scar of the central nervous system (CNS) has dual roles for inhibiting axon regeneration and promoting repair. However, it is poorly understood for formed and regulated mechanisms. M2 macrophages regulate fibrotic scar…