Explanipedia

Application of Comb-Type Fluorocarbon Polymer Surfactants as Dispersants in Insecticidal and Fungicidal Suspension Concentrates Open

Jingjing Zhang, Lingyun Song, Ruirui Ma, Junjie Kou, Yuxiu Liu , et al. · 2025

To investigate the application of novel comb-type fluorinated polymeric surfactants in suspension concentrates (SCs), we used the optimized surfactants (Comb-S 1, Comb-S 2, and Comb-S 3) as dispersants, with commercial dispersants as contr…

Progress in Gliotoxin Research Open

Li Li, Yuxiu Liu, Qingmin Wang, Hongjian Song · 2025

Gliotoxin, an important fungal secondary metabolite, belongs to the class of epidithiodiketopiperazines (ETPs) and exhibits various biological activities, including immunosuppression, induction of apoptosis, and antimicrobial, antiviral, a…

Design, Synthesis, and Biological Activity Studies of Aldisine Derivatives Containing Acylhydrazone Moiety Open

Wentao Xu, Kangkang Yang, Ming‐Xing Li, Li Li, Feng Xing , et al. · 2025

Marine natural products have gained increasing interest in drug research and development because of their unique structures, diverse biological activities, and novel mechanisms of action. Using the antiviral alkaloid aldisine as the lead c…

Responses of polar energy budget to regional sea surface temperature changes in extra-polar regions Open

Qingmin Wang, Yincheng Liu, Lujun Zhang, Chen Zhou · 2025

Surface temperature at polar regions not only is affected by local forcings and feedbacks but also depends on teleconnections between polar regions and low-latitude regions. In this study, the responses of the energy budget in polar region…

A strategy for the free‐formulation application of hydrophobic pesticides: achieving efficient and multifunctional utilization to promote green and sustainable agriculture Open

Xinxin Xu, Xiaodi Shi, Peng-Xuan Ding, Beibei Wang, Mengdie Zeng , et al. · 2025

BACKGROUND Pesticides are crucial agricultural production materials that ensure global food security. However, the hydrophobic nature of most pesticides makes direct field application impossible. Existing formulations for hydrophobic pesti…

Design, synthesis, and biological evaluation of novel derivatives of marine natural product ammosamide B Open

Mingjun Zhang, M. Li, Aidang Lu, Hongying Tang, Zhenghong Zhou , et al. · 2025

BACKGROUND Plant diseases caused by plant viruses and pathogens seriously affect crop yield and quality, making prevention and control extremely difficult and posing a serious threat to human health. Marine alkaloids have novel structures …

Truce-smiles rearrangement mediated by ligand-to-iron charge transfer Open

Fuyang Yue, Ming‐Xing Li, Kangkang Yang, Hongjian Song, Yuxiu Liu , et al. · 2025

Relationships Between Glymphatic System Activity and Tau Burden, Dopaminergic Impairment, Abnormal Glucose Metabolism in Progressive Supranuclear Palsy Open

Fangyang Jiao, Qingmin Wang, Jiayi Zhong, Huamei Lin, Jiaying Lu , et al. · 2025

Background Progressive supranuclear palsy (PSP) is a primary tauopathy characterized by dopaminergic impairment and abnormal glucose metabolism. The glymphatic system can promote the elimination of tau protein. The association between glym…

Discovery of Crinasiadine, Trisphaeridine, Bicolorine, and Their Derivatives as Anti-Tobacco Mosaic Virus (TMV) Agents Open

Zhan Hu, Jincheng Guo, Dejun Ma, Ziwen Wang, Yuxiu Liu , et al. · 2025

Plant viral diseases cause great harm to crops in terms of yield and quality. Natural products have been providing an excellent source of novel chemistry, inspiring the development of novel synthetic pesticides. The Amaryllidaceae alkaloid…

Notch Insensitivity of Strain-Hardening Fiber-Reinforced Cementitious Composites Incorporating Recycled Fine Aggregates Open

Han Zhang, Bo-Tao Huang, Qinghua Li, Qingmin Wang, Chaokun Hong , et al. · 2025

Biomimetic Dehydrogenative Intermolecular Formal Allylic Amidation of Branched α‐Olefins Open

Xiaoyang Fu, Jiarui Tian, Mingjun Zhang, Yue Jing, Yuxiu Liu , et al. · 2024

Allylic amide moieties are commonly encountered in natural products and are privileged structures in pharmaceuticals and agrochemicals. Moreover, because allylic amide can be to converted into an array of high‐value motifs, they have been …

Electrocatalytic regio- and stereoselective carboxylation of terminal alkynes with CO2 Open

Pan Zhou, Haoran Jiao, Yue Jing, Kaikai Niu, Hongjian Song , et al. · 2024

Design, Synthesis, and Acaricidal Activity of 2,5-Diphenyl-1,3-oxazoline Compounds Open

Yuming Chen, Jiarui Tian, Yuhao Tan, Yuxiu Liu, Qingmin Wang · 2024

By using a scaffold hopping/ring equivalent and intermediate derivatization strategies, a series of compounds of 2,5-diphenyl-1,3-oxazoline with substituent changes at the 5-phenyl position were prepared, and their acaricidal activity was …

Responses of polar energy budget to regional SST changes in extra-polar regions Open

Qingmin Wang, Yincheng Liu, Lujun Zhang, Chen Zhou · 2024

Surface temperature at polar regions is not only affected by local forcings and feedbacks, but also depends on teleconnections between polar regions and low latitude regions. In this study, the responses of energy budget in polar regions t…

Nipocalimab, an anti-FcRn monoclonal antibody, in participants with moderate to severe active rheumatoid arthritis and inadequate response or intolerance to anti-TNF therapy: results from the phase 2a IRIS-RA study Open

Peter C. Taylor, Georg Schett, T. Huizinga, Qingmin Wang, Fowzia Ibrahim , et al. · 2024

Objectives To investigate the efficacy, safety, pharmacokinetics and pharmacodynamics of nipocalimab in participants with moderate to severe active rheumatoid arthritis (RA) and inadequate response or intolerance to ≥1 antitumour necrosis …

Deboronative functionalization of alkylboron species <i>via</i> a radical-transfer strategy Open

Fuyang Yue, Mingxing Li, Kangkang Yang, Hongjian Song, Yuxiu Liu , et al. · 2024

We describe a method for activating C–B bonds by nitrogen- or oxygen-radical transfer that is applicable to alkylboronic acids and esters.

CCDC 2120350: Experimental Crystal Structure Determination Open

Pan Zhou, Senhui Wu, Kaikai Niu, Hongjian Song, Yuxiu Liu , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Deep learning algorithm using bispectrum analysis energy feature maps based on ultrasound radiofrequency signals to detect breast cancer Open

Qingmin Wang, Xiaohong Jia, Ting Luo, Jinhua Yu, Shujun Xia · 2023

Background Ultrasonography is an important imaging method for clinical breast cancer screening. As the original echo signals of ultrasonography, ultrasound radiofrequency (RF) signals provide abundant tissue macroscopic and microscopic inf…

Formation of C–B, C–C, and C–X Bonds from Nonstabilized Aryl Radicals Generated from Diaryl Boryl Radicals Open

Fuyang Yue, Henan Ma, Peng-Xuan Ding, Hongjian Song, Yuxiu Liu , et al. · 2023

With the development of organoboron chemistry, boron-centered radicals have become increasingly attractive. However, their synthetic applications remain limited in that they have been used only as substrates for addition reactions or as in…

How Does Internet Use Promote Returned Migrant Workers’ Entrepreneurship: Evidence from Rural China Open

Yashuo Xue, Mei Kong, Ruiying Chen, Qingmin Wang, Yangyang Shen , et al. · 2023

Entrepreneurship is the driving force behind the creation of rural employment opportunities and the promotion of the sustainable development of the rural economy. Based on the data of five rounds of national surveys covering the period fro…

Direct allylic acylation via cross-coupling involving cooperative N‑heterocyclic carbene, hydrogen atom transfer, and photoredox catalysis Open

Xiaochen Wang, Rongxin Yang, Binbing Zhu, Yuxiu Liu, Hongjian Song , et al. · 2023

Design, Synthesis and Various Bioactivity of Acylhydrazone-Containing Matrine Analogues Open

Wanjun Ni, Hongjian Song, Lizhong Wang, Yuxiu Liu, Qingmin Wang · 2023

Compounds with acylhydrazone fragments contain amide and imine groups that can act as electron donors and acceptors, so they are easier to bind to biological targets and thus generally exhibit significant biological activity. In this work,…

The causal role of intestinal microbiome in development of pre-eclampsia Open

Zhihui Xiong, Qingmin Wang, Shuping Pei, Zheng Zhu · 2023

The correlation of pre-eclampsia (PE) and intestinal microbiome has been widely demonstrated in existing research, whereas their causal relationship has been rarely explored. The causal relationship between intestinal microbiome and PE ris…

Natural Products for Pesticides Discovery: Structural Diversity Derivation and Biological Activities of Naphthoquinones Plumbagin and Juglone Open

Kaihua Wang, Beibei Wang, Henan Ma, Ziwen Wang, Yuxiu Liu , et al. · 2023

Plant diseases and insect pests seriously affect the yield and quality of crops and are difficult to control. Natural products are an important source for the discovery of new pesticides. In this work, naphthoquinones plumbagin and juglone…

Discovery of Barakacin and Its Derivatives as Novel Antiviral and Fungicidal Agents Open

Yongyue Gao, Xingxing He, Lili Yan, Hongyu Zhang, Sijia Liu , et al. · 2023

Pesticides are essential for the development of agriculture. It is urgent to develop green, safe and efficient pesticides. Bisindole alkaloids have unique and concise structures and broad biological activities, which make them an important…

The efficacy of Kangaroo-Mother care to the clinical outcomes of LBW and premature infants in the first 28 days: A meta-analysis of randomized clinical trials Open

Zhen Zhu, Xinchen Wang, Wenzeng Chen, Shuping Pei, Qingmin Wang , et al. · 2023

Objective The objective of this study was to systematically determine the benefits of Kangaroo-Mother Care (KMC) on the clinical outcomes of low birthweight (LBW) and preterm infants. Methods For this study, the following databases were re…

Structural Size Effect in the Mode I and Mixed Mode I/Ii Fracture of Strain-Hardening Cementitious Composites (Shcc) Open

Qingmin Wang, Qinghua Li, Xing Yin, Shilang Xu · 2023

Direct Allylic Acylation via Cross-Coupling Involving Cooperative N‑Heterocyclic Carbene, Hydrogen Atom Transfer, and Photoredox Catalysis Open

Qingmin Wang · 2023

Direct Allylic Acylation via Cross-Coupling Involving Cooperative N‑Heterocyclic Carbene, Hydrogen Atom Transfer, and Photoredox Catalysis

Recent advances in combining photo- and N-heterocyclic carbene catalysis Open

Xiaochen Wang, Senhui Wu, Rongxin Yang, Hongjian Song, Yuxiu Liu , et al. · 2023

This review summarizes recent advances in combining photo- and N-heterocyclic carbene catalysis, as well as provides an outlook on future opportunities and challenges.

Research progress of anti-plant virus agents based on marine natural products Open

Hongjian Song, Yuxiu Liu, Qingmin Wang · 2022

Plant virus diseases are a serious threat to food crops, vegetables, and cash crops, their prevention and control are extremely difficult, known as ‘plant cancer’, and effective prevention and control agents are extremely short. Environmen…

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