Qingming Wu
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View article: Development, validation, and web deployment of a rebleeding risk prediction model for acute non-variceal upper gastrointestinal bleeding in a Chinese population
Development, validation, and web deployment of a rebleeding risk prediction model for acute non-variceal upper gastrointestinal bleeding in a Chinese population Open
Background Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) is a common life-threatening emergency. Despite advances in endoscopic hemostasis, the 7-day rebleeding rate remains as high as 15–30%. Existing risk assessment tools …
View article: Three Decades of Habitat Loss and Northward Shift in the Red-Crowned Crane on the Songnen Plain: Conservation Gaps and the Need for Network Expansion
Three Decades of Habitat Loss and Northward Shift in the Red-Crowned Crane on the Songnen Plain: Conservation Gaps and the Need for Network Expansion Open
The red-crowned crane (Grus japonensis) is a flagship species for wetland biodiversity in East Asia. The Songnen Plain is a vital wetland and habitat for rare and endangered birds in Northeast China. However, rapid land use changes have ra…
View article: Investigation into the Relationship between Gut Microbiota of Cranes and Their Feeding Environment in the Yellow River Delta
Investigation into the Relationship between Gut Microbiota of Cranes and Their Feeding Environment in the Yellow River Delta Open
The gut microbiota plays essential roles in host health and environmental adaptation, particularly for migratory birds within wetland ecosystems. This study examined the gut microbial communities of common cranes ( Grus grus ) and White Cr…
View article: Avian Biodiversity Response Toward Ecological Restoration of Wetlands Through Farmland Abandonment Measures in the Sanjiang Plain, China
Avian Biodiversity Response Toward Ecological Restoration of Wetlands Through Farmland Abandonment Measures in the Sanjiang Plain, China Open
Large-scale agricultural development has led to a significant reduction in wetland areas, resulting in habitat fragmentation for birds and biodiversity loss. Recently, the implementation of farmland abandonment policies has helped in the r…
View article: Comparative Analysis of Perceived Threat Threshold from Various Drivers to Cranes Along Indus Flyway, Punjab, Pakistan
Comparative Analysis of Perceived Threat Threshold from Various Drivers to Cranes Along Indus Flyway, Punjab, Pakistan Open
Migratory birds globally face escalating anthropogenic threats, with crane species being particularly vulnerable. This study assessed human-perceived threats to cranes (Grus virgo & Grus grus) along Pakistan’s vital Indus Flyway using 400 …
View article: Chinese expert consensus on the application of intravenous immunoglobulin in hematological diseases
Chinese expert consensus on the application of intravenous immunoglobulin in hematological diseases Open
Intravenous immunoglobulin (IVIG), first developed for the treatment of patients with antibody deficiencies, is now widely used in clinical practice, especially in hematological and immune system diseases, and its application in hematologi…
View article: The predictive value of FAH model for the occurrence of colorectal cancer
The predictive value of FAH model for the occurrence of colorectal cancer Open
Background Fatty liver is characterized by hepatic steatosis and is associated with dyslipidemia and insulin resistance. Carotid atherosclerosis, characterized by plaque formation, may be related to increased lipid deposition. High-density…
View article: Urbanization Influences on the Song Diversity of the Eurasian Nuthatch (Sitta europaea) in Northeast China
Urbanization Influences on the Song Diversity of the Eurasian Nuthatch (Sitta europaea) in Northeast China Open
The continuous advancement of urbanization and the expansion of cities inevitably have certain impacts on urban wildlife. Birds are a highly visible group of urban wildlife, widely distributed and sensitive to environmental changes. Birds’…
View article: Research progress on fecal microbiota transplantation in tumor prevention and treatment
Research progress on fecal microbiota transplantation in tumor prevention and treatment Open
The application of fecal microbiota transplantation (FMT) as a therapeutic strategy to directly modify the makeup of the gut microbiota has made significant progress in the last few decades. The gut microbiota, a sizable microbial communit…
View article: miR-1247-3p regulation of CCND1 affects chemoresistance in colorectal cancer
miR-1247-3p regulation of CCND1 affects chemoresistance in colorectal cancer Open
The effectiveness of chemotherapy involving 5-fluorouracil and cisplatin (DDP) for the treatment of colorectal cancer (CRC) is often limited due to the emergence of drug resistance. An increasing body of research highlights the crucial rol…
View article: Causal associations of metabolic dysfunction-associated steatotic liver disease with gestational hypertension and preeclampsia: a two-sample Mendelian randomization study
Causal associations of metabolic dysfunction-associated steatotic liver disease with gestational hypertension and preeclampsia: a two-sample Mendelian randomization study Open
This MR study provided evidence supporting the causal effect of MASLD on GH. Our findings underscore the significance of providing more intensive prenatal care and early intervention for pregnant women with MASLD to prevent potential adver…
View article: Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis
Causal relationship between Women’s reproductive traits and postpartum depression: a multivariate mendelian randomization analysis Open
Purpose The relationship between women’s reproductive traits and postpartum depression (PPD) has not been clarified. We reveal the association between genetically predicted modifiable women’s reproductive traits and PPD using two-sample Me…
View article: Breaking the barrier: Epigenetic strategies to combat platinum resistance in colorectal cancer
Breaking the barrier: Epigenetic strategies to combat platinum resistance in colorectal cancer Open
Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. Platinum-based drugs, such as cisplatin and oxaliplatin, are frontline chemotherapy for CRC, effective in both monotherapy and combination regimens. However,…
View article: Chinese guidelines for integrated diagnosis and treatment of intestinal microecology technologies in tumor application (2024 Edition)
Chinese guidelines for integrated diagnosis and treatment of intestinal microecology technologies in tumor application (2024 Edition) Open
Intestinal microecology (IM) is the largest and most important microecological system of the human body. Furthermore, it is the key factor for activating and maintaining the physiological functions of the intestine. Numerous studies have i…
View article: Population Dynamics and Habitat Preferences of Waterbirds across Six Wetlands at Different Geographical Scales
Population Dynamics and Habitat Preferences of Waterbirds across Six Wetlands at Different Geographical Scales Open
Wetlands are vital ecosystems for waterbirds, are experiencing global decline due to human activities. Our study investigated the population dynamics and habitat preferences of waterbirds in six geographically distinct wetlands (Chashma, D…
View article: Evaluation of Lake Fragmentation and Its Effect on Wintering Waterbirds in Poyang Lake, China
Evaluation of Lake Fragmentation and Its Effect on Wintering Waterbirds in Poyang Lake, China Open
This study was designed to determine the fragmentation of sub-lakes in winter and its effects on wintering waterbirds in Poyang Lake. Poyang Lake becomes fragmented in winter, which forms many seasonal sub-lakes every year, and have differ…
View article: Chinese expert consensus on the management of patients with hematologic malignancies infected with SARS-CoV-2
Chinese expert consensus on the management of patients with hematologic malignancies infected with SARS-CoV-2 Open
In December 2022, the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became dominant in China due to its high infectivity and lower mortality rate. The risk of critical illness and mortality among patients …
View article: Oral Pathogenic Bacteria and the Oral–Gut–Liver Axis: A New Understanding of Chronic Liver Diseases
Oral Pathogenic Bacteria and the Oral–Gut–Liver Axis: A New Understanding of Chronic Liver Diseases Open
Liver diseases have long been a prevalent cause of morbidity and mortality, and their development and progression involve multiple vital organs throughout the body. Recent studies on the oral–gut–liver axis have revealed that the oral micr…
View article: Causal relationship between Women's reproductive traits and postpartum depression: a multivariate Mendelian randomization analysis
Causal relationship between Women's reproductive traits and postpartum depression: a multivariate Mendelian randomization analysis Open
Background: The relationship between women's reproductive traits and postpartum depression (PPD) has not been clarified. We reveal the association between genetically predicted modifiable women’s reproductive traits and PPD using two-sampl…
View article: Ophiopogonin D ameliorates non‑alcoholic fatty liver disease in high‑fat diet‑induced obese mice by improving lipid metabolism, oxidative stress and inflammatory response
Ophiopogonin D ameliorates non‑alcoholic fatty liver disease in high‑fat diet‑induced obese mice by improving lipid metabolism, oxidative stress and inflammatory response Open
Lipid metabolic disorders, oxidative stress and inflammation in the liver are key steps in the progression of non-alcoholic fatty liver disease (NAFLD). Ophiopogonin D (OP-D), the main active ingredient of Ophiopogon japonicus, exhibits se…
View article: Metabolomic analysis of gut metabolites in patients with colorectal cancer: Association with disease development and outcome
Metabolomic analysis of gut metabolites in patients with colorectal cancer: Association with disease development and outcome Open
Colorectal cancer (CRC) is one of the leading global malignancies with low 5-year survival and high mortality rates. Despite extensive research, the precise role of gut metabolites in CRC development and clinical outcomes remains unclear, …
View article: Chinese expert consensus on intestinal microecology and management of digestive tract complications related to tumor treatment (version 2022)
Chinese expert consensus on intestinal microecology and management of digestive tract complications related to tumor treatment (version 2022) Open
The human gut microbiota represents a complex ecosystem that is composed of bacteria, fungi, viruses, and archaea. It affects many physiological functions including metabolism, inflammation, and the immune response. The gut microbiota also…
View article: Oral Microbiota and Tumor—A New Perspective of Tumor Pathogenesis
Oral Microbiota and Tumor—A New Perspective of Tumor Pathogenesis Open
Microorganisms have long been known to play key roles in the initiation and development of tumors. The oral microbiota and tumorigenesis have been linked in epidemiological research relating to molecular pathology. Notably, some bacteria c…
View article: LINC02418 upregulates EPHA2 by competitively sponging miR-372-3p to promote 5-Fu/DDP chemoresistance in colorectal cancer
LINC02418 upregulates EPHA2 by competitively sponging miR-372-3p to promote 5-Fu/DDP chemoresistance in colorectal cancer Open
Chemoresistance is a huge clinical challenge in the treatment of advanced colorectal cancer (CRC). Non-coding RNAs (ncRNAs) and messenger RNA (mRNA) are involved in CRC chemoresistance. However, the profiles of long ncRNAs (lncRNAs), micro…
View article: Virtual Simulation in Undergraduate Medical Education: A Scoping Review of Recent Practice
Virtual Simulation in Undergraduate Medical Education: A Scoping Review of Recent Practice Open
Virtual simulation (VS) as an emerging interactive pedagogical strategy has been paid more and more attentions in the undergraduate medical education. Because of the fast development of modern computer simulation technologies, more and mor…