Qian Su
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View article: The role of chest X-ray in tuberculosis detection for high school students in China: a cross-sectional study
The role of chest X-ray in tuberculosis detection for high school students in China: a cross-sectional study Open
In China, pulmonary tuberculosis (PTB) screening for children and adolescents is not only focused on family contacts, but also students in high schools. The research objective is to investigate chest X-ray (CXR) abnormalities and its risk …
View article: The genetic architecture of brainstem structures
The genetic architecture of brainstem structures Open
The brainstem houses numerous nuclei and tracts that serve vital functions. Genome-wide associations with brainstem substructure volumes have been explored in European individuals, yet other ancestries remain under-represented. Here, we co…
View article: EXPRESS: Exploring circRNA_19601 as a therapeutic target in diabetic neuropathic pain: insights from rat and cell models
EXPRESS: Exploring circRNA_19601 as a therapeutic target in diabetic neuropathic pain: insights from rat and cell models Open
Background: Diabetic neuropathic pain (DNP) is a common complication of diabetes with significant impact on patients' quality of life. Current treatments have limitations, and exploring new mechanisms and targets is crucial. Objective: Our…
View article: The study of dual-phase 18F-FDG PET/CT-based models in predicting malignant solitary pulmonary lesions
The study of dual-phase 18F-FDG PET/CT-based models in predicting malignant solitary pulmonary lesions Open
The morphology of benign and malignant solitary pulmonary lesions sometimes overlaps, making the differentiation difficult. This research aimed to create a radiomics-based prediction model using dual-phase 18F-fluorodeoxyglucose…
View article: Relapsing polychondritis with isolated tracheal involvement: Imaging findings on CT, MRI, and PET-CT: A case report and literature review
Relapsing polychondritis with isolated tracheal involvement: Imaging findings on CT, MRI, and PET-CT: A case report and literature review Open
Relapsing polychondritis (RP) is a rare autoimmune disorder characterized by recurrent inflammation and progressive destruction of cartilage-rich tissues. While auricular and nasal cartilage are commonly affected, isolated involvement of t…
View article: Engineering Schottky Junction Nanocatalysts for Enhanced Charge Carrier Separation and Synergistic PDT/PTT/CDT in Bladder Cancer Therapy
Engineering Schottky Junction Nanocatalysts for Enhanced Charge Carrier Separation and Synergistic PDT/PTT/CDT in Bladder Cancer Therapy Open
Bladder cancer is one of the most prevalent malignancies of the urinary system and poses significant therapeutic challenges, including high recurrence rates, drug resistance, and treatment-related side effects. In recent years, Schottky ju…
View article: Efficacy and safety of anlotinib in combination with ¹³¹I therapy in the treatment of distant metastatic differentiated thyroid cancer: a single-arm, phase II study
Efficacy and safety of anlotinib in combination with ¹³¹I therapy in the treatment of distant metastatic differentiated thyroid cancer: a single-arm, phase II study Open
Background Radioactive iodine (RAI) is the standard treatment for distant metastatic differentiated thyroid cancer (dmDTC). However, many patients fail to achieve satisfactory effects and prognosis. Anlotinib is a highly effective antiangi…
View article: Selective disruption of gray matter volume covariance in orbitofrontal cortex subregions among patients with functional constipation
Selective disruption of gray matter volume covariance in orbitofrontal cortex subregions among patients with functional constipation Open
Functional constipation (FCon) is a prevalent common functional gastrointestinal disorders (FGIDs) frequently linked to mental and psychological disorders. Although previous studies have demonstrated alterations in brain structure and func…
View article: Prediction of pathological complete response to neoadjuvant chemoimmunotherapy in non–small cell lung cancer using 18F-FDG PET radiomics features of primary tumour and lymph nodes
Prediction of pathological complete response to neoadjuvant chemoimmunotherapy in non–small cell lung cancer using 18F-FDG PET radiomics features of primary tumour and lymph nodes Open
View article: Function‐Specific Localization in the Supplementary Motor Area: A Potential Effective Target for Tourette Syndrome
Function‐Specific Localization in the Supplementary Motor Area: A Potential Effective Target for Tourette Syndrome Open
Aims Repetitive transcranial magnetic stimulation (rTMS) targeting the supplementary motor area (SMA) may treat Tourette's syndrome (TS) by modulating the function of the globus pallidus internus (GPi) via the cortico‐striato‐thalamo‐corti…
View article: Underestimated latent tuberculosis infection burden among school contacts in China: a cross-sectional study
Underestimated latent tuberculosis infection burden among school contacts in China: a cross-sectional study Open
View article: 18F-FDG PET/CT-based habitat radiomics combining stacking ensemble learning for predicting prognosis in hepatocellular carcinoma: a multi-center study
18F-FDG PET/CT-based habitat radiomics combining stacking ensemble learning for predicting prognosis in hepatocellular carcinoma: a multi-center study Open
This study was a retrospective study, so it was free from registration.
View article: Pain‐Discriminating Information Decoded From Spatiotemporal Patterns of Hemodynamic Responses Measured by <scp>fMRI</scp> in the Human Brain
Pain‐Discriminating Information Decoded From Spatiotemporal Patterns of Hemodynamic Responses Measured by <span>fMRI</span> in the Human Brain Open
Functional magnetic resonance imaging (fMRI) has been widely used in studying the neural mechanisms of pain in the human brain, primarily focusing on where in the brain pain‐elicited neural activities occur (i.e., the spatial distribution …
View article: Causal relationships between cortical brain structural alterations and migraine subtypes: a bidirectional Mendelian randomization study of 2,347 neuroimaging phenotypes
Causal relationships between cortical brain structural alterations and migraine subtypes: a bidirectional Mendelian randomization study of 2,347 neuroimaging phenotypes Open
View article: The Role of Chest X-ray in Tuberculosis Detection for High School Students in China: A Cross-sectional Study
The Role of Chest X-ray in Tuberculosis Detection for High School Students in China: A Cross-sectional Study Open
Background In China, pulmonary tuberculosis (PTB) screening for children and adolescents is not only focused on family contacts, but also students in high schools. The research objective is to investigate chest X-ray (CXR) abnormalities an…
View article: Unraveling multi‐scale neuroimaging biomarkers and molecular foundations for schizophrenia: A combined multivariate pattern analysis and transcriptome‐neuroimaging association study
Unraveling multi‐scale neuroimaging biomarkers and molecular foundations for schizophrenia: A combined multivariate pattern analysis and transcriptome‐neuroimaging association study Open
Aims Schizophrenia is characterized by alterations in resting‐state spontaneous brain activity; however, it remains uncertain whether variations at diverse spatial scales are capable of effectively distinguishing patients from healthy cont…
View article: Addressing The Burden and Detection Gap of Latent Tuberculosis Infection In Schoolchildren and Adolescents In China: A Cross-Sectional Study
Addressing The Burden and Detection Gap of Latent Tuberculosis Infection In Schoolchildren and Adolescents In China: A Cross-Sectional Study Open
View article: Transcriptional correlates of frequency-dependent brain functional activity associated with symptom severity in degenerative cervical myelopathy
Transcriptional correlates of frequency-dependent brain functional activity associated with symptom severity in degenerative cervical myelopathy Open
In conclusion, our study bridges gaps between genes, cell classes, biological processes, and brain functional correlates of DCM. While our findings are correlational in nature, they suggest that the neural activities of sensorimotor cortic…
View article: Functional Connectome Hierarchy Distortions in Female Nurses With Occupational Burnout and Its Gene Expression Signatures
Functional Connectome Hierarchy Distortions in Female Nurses With Occupational Burnout and Its Gene Expression Signatures Open
Background Burnout has become a serious public health issue worldwide, particularly during the COVID‐19 pandemic. Functional connectome impairments associated with occupational burnout were widely distributed, involving both low‐level sens…
View article: Birth cohort changes in anxiety levels among primary school students in China during 1995–2019: A cross-temporal meta-analysis
Birth cohort changes in anxiety levels among primary school students in China during 1995–2019: A cross-temporal meta-analysis Open
To investigate birth cohort changes in anxiety levels among primary school students in China, we conducted a cross-temporal meta-analysis of 126 studies (N = 109,957) reporting the anxiety levels among primary school students in China duri…
View article: Both fine-grained and coarse-grained spatial patterns of neural activity measured by functional MRI show preferential encoding of pain in the human brain
Both fine-grained and coarse-grained spatial patterns of neural activity measured by functional MRI show preferential encoding of pain in the human brain Open
How pain emerges from human brain remains an unresolved question in pain neuroscience. Neuroimaging studies have suggested that all brain areas activated by painful stimuli were also activated by tactile stimuli, and vice versa. Nonetheles…
View article: Preoperative pain hypersensitivity is associated with axial pain after posterior cervical spinal surgeries in degenerative cervical myelopathy patients: a preliminary resting-state fMRI study
Preoperative pain hypersensitivity is associated with axial pain after posterior cervical spinal surgeries in degenerative cervical myelopathy patients: a preliminary resting-state fMRI study Open
Objective To test whether preoperative pain sensitivity is associated with the postoperative axial pain (PAP) in degenerative cervical myelopathy (DCM) and to explore its underlying brain mechanism. Methods Clinical data and resting-state …
View article: Transcriptional Correlates of Frequency-Dependent Brain Functional Plasticity Associated with Symptom Severity in Degenerative Cervical Myelopathy
Transcriptional Correlates of Frequency-Dependent Brain Functional Plasticity Associated with Symptom Severity in Degenerative Cervical Myelopathy Open
View article: Curcumin suppresses cell proliferation and reduces cholesterol absorption in Caco-2 cells by activating the TRPA1 channel
Curcumin suppresses cell proliferation and reduces cholesterol absorption in Caco-2 cells by activating the TRPA1 channel Open
Background: Curcumin (Cur) is a bioactive dietary polyphenol of turmeric with various biological activities against several cancers. Colorectal cancer (CRC) is one of the leading causes of cancer mortality worldwide. Intestinal cholesterol…
View article: Brain-activation-based individual identification reveals individually unique activation patterns elicited by pain and touch
Brain-activation-based individual identification reveals individually unique activation patterns elicited by pain and touch Open
Pain is subjective and perceived differently in different people. However, individual differences in pain-elicited brain activations are largely overlooked and often discarded as noises. Here, we used a brain-activation-based individual id…
View article: Circular RNA expression alteration and bioinformatics analysis in patients with acute cerebral infarction injury
Circular RNA expression alteration and bioinformatics analysis in patients with acute cerebral infarction injury Open
In recent years, a steady increase has been detected in the incidence of acute cerebral infarction (ACI). ACI is caused by blood flow disruption, leading to high disability and mortality rates. Understanding the underlying molecular mechan…
View article: MiR-149-5p: An Important miRNA Regulated by Competing Endogenous RNAs in Diverse Human Cancers
MiR-149-5p: An Important miRNA Regulated by Competing Endogenous RNAs in Diverse Human Cancers Open
MicroRNAs (miRNAs) consist of a large family of small, non-coding RNAs with the ability to result in gene silencing post-transcriptionally. With recent advances in research technology over the past several years, the physiological and path…
View article: Identification and Therapeutic Outcome Prediction of Cervical Spondylotic Myelopathy Based on the Functional Connectivity From Resting-State Functional MRI Data: A Preliminary Machine Learning Study
Identification and Therapeutic Outcome Prediction of Cervical Spondylotic Myelopathy Based on the Functional Connectivity From Resting-State Functional MRI Data: A Preliminary Machine Learning Study Open
Currently, strategies to diagnose patients and predict neurological recovery in cervical spondylotic myelopathy (CSM) using MR images of the cervical spine are urgently required. In light of this, this study aimed at exploring potential pr…
View article: Corrigendum: Prediction of EGFR Mutation Status Based on 18F-FDG PET/CT Imaging Using Deep Learning-Based Model in Lung Adenocarcinoma
Corrigendum: Prediction of EGFR Mutation Status Based on 18F-FDG PET/CT Imaging Using Deep Learning-Based Model in Lung Adenocarcinoma Open
[This corrects the article DOI: 10.3389/fonc.2021.709137.].
View article: Prediction of EGFR Mutation Status Based on 18F-FDG PET/CT Imaging Using Deep Learning-Based Model in Lung Adenocarcinoma
Prediction of EGFR Mutation Status Based on 18F-FDG PET/CT Imaging Using Deep Learning-Based Model in Lung Adenocarcinoma Open
Objective The purpose of this study was to develop a deep learning-based system to automatically predict epidermal growth factor receptor (EGFR) mutant lung adenocarcinoma in 18 F-fluorodeoxyglucose (FDG) positron emission tomography/compu…