Qiuling He
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View article: Reducing Mineral Fertilizer Can Improve the Soil Quality and Increase the Wheat Yield and Nutrient Utilization Efficiency: The Fertilizing Effect of Organic–Inorganic Compound Fertilizers
Reducing Mineral Fertilizer Can Improve the Soil Quality and Increase the Wheat Yield and Nutrient Utilization Efficiency: The Fertilizing Effect of Organic–Inorganic Compound Fertilizers Open
Replacing chemical fertilizers with organic alternatives represents a viable strategy for enhancing agricultural productivity. The optimized integration of both fertilizer types can reduce the chemical input while improving soil conditions…
View article: Physiological, Cytological and Transcriptome Analysis of a Yellow–Green Leaf Mutant in Magnolia sinostellata
Physiological, Cytological and Transcriptome Analysis of a Yellow–Green Leaf Mutant in Magnolia sinostellata Open
Leaf color mutants serve as excellent models for investigating the metabolic pathways involved in chlorophyll biosynthesis, chloroplast development, and photosynthesis in plants. This study aimed to elucidate the mechanisms underlying colo…
View article: Programmable “triple attack” cancer therapy through <i>in situ</i> activation of disulfiram toxification combined with phototherapeutics
Programmable “triple attack” cancer therapy through <i>in situ</i> activation of disulfiram toxification combined with phototherapeutics Open
A programmable “triple attack” cancer treatment strategy is proposed via in situ disulfiram toxification activation combined with NIR-II phototherapeutics.
View article: mRNA-Seq and miRNA-Seq Analyses Provide Insights into the Mechanism of Pinellia ternata Bulbil Initiation Induced by Phytohormones
mRNA-Seq and miRNA-Seq Analyses Provide Insights into the Mechanism of Pinellia ternata Bulbil Initiation Induced by Phytohormones Open
Pinellia ternata (Thunb.) Breit (abbreviated as P. ternata) is a plant with an important medicinal value whose yield is restricted by many factors, such as low reproductive efficiency and continuous cropping obstacles. As an essential bree…
View article: Assessment of Genetic Diversity in Bupleurum spp. Basing Agronomic Traits, Medicinal Components and ISSR Markers
Assessment of Genetic Diversity in Bupleurum spp. Basing Agronomic Traits, Medicinal Components and ISSR Markers Open
Radix bupleuri is one of the bulk medicinal materials in China and it is widely adopted in clinical applications and drug discovery. The investigation of agronomic traits, active component content and genetic diversity in diverse Radix bup…
View article: Screening out Biomarkers of Tetrastigma hemsleyanum for Anti-Cancer and Anti-Inflammatory Based on Spectrum-Effect Relationship Coupled with UPLC-Q-TOF-MS
Screening out Biomarkers of Tetrastigma hemsleyanum for Anti-Cancer and Anti-Inflammatory Based on Spectrum-Effect Relationship Coupled with UPLC-Q-TOF-MS Open
Tetrastigma hemsleyanum Diels et Gilg. (T. hemsleyanum) is an economically and medicinally valuable species within the genus Tetrastigma. However, the material basis of its pharmacological action and the biomarkers associated with its anti…
View article: Systematic Identification and Validation of Suitable Reference Genes for the Normalization of Gene Expression in Prunella vulgaris under Different Organs and Spike Development Stages
Systematic Identification and Validation of Suitable Reference Genes for the Normalization of Gene Expression in Prunella vulgaris under Different Organs and Spike Development Stages Open
The quantitative real-time PCR (qRT-PCR) is an efficient and sensitive method for determining gene expression levels, but the accuracy of the results substantially depends on the stability of the reference gene (RG). Therefore, choosing an…
View article: Characterization and Comparative Analysis of Chloroplast Genomes in Five Uncaria Species Endemic to China
Characterization and Comparative Analysis of Chloroplast Genomes in Five Uncaria Species Endemic to China Open
Uncaria, a perennial vine from the Rubiaceae family, is a typical Chinese traditional medicine. Currently, uncertainty exists over the Uncaria genus’ evolutionary relationships and germplasm identification. The complete chloroplast genomes…
View article: SSR Loci Analysis in Transcriptome and Molecular Marker Development in <i>Polygonatum sibiricum</i>
SSR Loci Analysis in Transcriptome and Molecular Marker Development in <i>Polygonatum sibiricum</i> Open
To study the SSR loci information and develop molecular markers, a total of 435,858 unigenes in transcriptome of Polygonatum sibiricum were used to explore SSR. The distribution frequency of SSR and the basic characteristics of repeat moti…
View article: Genome-Wide Characterization and Expression Analysis of bZIP Gene Family Under Abiotic Stress in Glycyrrhiza uralensis
Genome-Wide Characterization and Expression Analysis of bZIP Gene Family Under Abiotic Stress in Glycyrrhiza uralensis Open
bZIP gene family is one of the largest transcription factor families. It plays an important role in plant growth, metabolic, and environmental response. However, complete genome-wide investigation of bZIP gene family in Glycyrrhiza uralens…
View article: Melatonin enhances cotton immunity to <i>Verticillium</i> wilt via manipulating lignin and gossypol biosynthesis
Melatonin enhances cotton immunity to <i>Verticillium</i> wilt via manipulating lignin and gossypol biosynthesis Open
Summary Plants endure challenging environments in which they are constantly threatened by diverse pathogens. The soil‐borne fungus Verticillium dahliae is a devastating pathogen affecting many plant species including cotton, in which it si…
View article: Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria
Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria Open
Once-monthly injections of givosiran in patients who had recurrent porphyria attacks resulted in mainly low-grade adverse events, reductions in induced ALAS1 mRNA levels, nearly normalized levels of the neurotoxic intermediates delta amino…
View article: Additional file 3: of Identification and profiling of upland cotton microRNAs at fiber initiation stage under exogenous IAA application
Additional file 3: of Identification and profiling of upland cotton microRNAs at fiber initiation stage under exogenous IAA application Open
Table S3. Names and sequences of the identified novel miRNAs in six libraries. (XLSX 11 kb)
View article: Additional file 4: of Identification and profiling of upland cotton microRNAs at fiber initiation stage under exogenous IAA application
Additional file 4: of Identification and profiling of upland cotton microRNAs at fiber initiation stage under exogenous IAA application Open
Structures of all the identified novel miRNAs. (ZIP 1005 kb)
View article: Additional file 5: of Identification and profiling of upland cotton microRNAs at fiber initiation stage under exogenous IAA application
Additional file 5: of Identification and profiling of upland cotton microRNAs at fiber initiation stage under exogenous IAA application Open
Table S4. MiRNAs and the corresponding target genes. (XLSX 30 kb)
View article: Additional file 2: of Identification and profiling of upland cotton microRNAs at fiber initiation stage under exogenous IAA application
Additional file 2: of Identification and profiling of upland cotton microRNAs at fiber initiation stage under exogenous IAA application Open
Table S2. Names and sequences of the identified known miRNAs in six libraries. (XLSX 10 kb)
View article: Genome-wide identification of membrane-bound fatty acid desaturase genes in Gossypium hirsutum and their expressions during abiotic stress
Genome-wide identification of membrane-bound fatty acid desaturase genes in Gossypium hirsutum and their expressions during abiotic stress Open
Membrane-bound fatty acid desaturases (FADs) are of great importance and play multiple roles in plant growth and development. In the present study, 39 full-length FAD genes, based on database searches, were identified in tetraploid upland …
View article: Genome-Wide Identification of R2R3-MYB Genes and Expression Analyses During Abiotic Stress in Gossypium raimondii
Genome-Wide Identification of R2R3-MYB Genes and Expression Analyses During Abiotic Stress in Gossypium raimondii Open
The R2R3-MYB is one of the largest families of transcription factors, which have been implicated in multiple biological processes. There is great diversity in the number of R2R3-MYB genes in different plants. However, there is no report on…
View article: Glutathione S-Transferase Gene Family in Gossypium raimondii and G. arboreum: Comparative Genomic Study and their Expression under Salt Stress
Glutathione S-Transferase Gene Family in Gossypium raimondii and G. arboreum: Comparative Genomic Study and their Expression under Salt Stress Open
Glutathione S-transferases (GSTs) play versatile functions in multiple aspects of plant growth and development. A comprehensive genome-wide survey of this gene family in the genomes of G. raimondii and G. arboreum was carried out in this s…
View article: Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling
Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling Open
Significance Cervical cancer (CxCa) is the second most frequent cancer in women and the third leading cause of cancer death in women worldwide. Our global analysis of gene expression in normal, precancerous, and cancerous cervical tissue s…
View article: Characterization of 19 Genes Encoding Membrane-Bound Fatty Acid Desaturases and their Expression Profiles in Gossypium raimondii Under Low Temperature
Characterization of 19 Genes Encoding Membrane-Bound Fatty Acid Desaturases and their Expression Profiles in Gossypium raimondii Under Low Temperature Open
To produce unsaturated fatty acids, membrane-bound fatty acid desaturases (FADs) can be exploited to introduce double bonds into the acyl chains of fatty acids. In this study, 19 membrane-bound FAD genes were identified in Gossypium raimon…