Qingyuan Deng
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View article: Hyperbaric Oxygen Regulates Tumor pH to Boost Copper‐Doped Hydroxyethyl Starch Conjugate Nanoparticles Against Cancer Stem Cells
Hyperbaric Oxygen Regulates Tumor pH to Boost Copper‐Doped Hydroxyethyl Starch Conjugate Nanoparticles Against Cancer Stem Cells Open
An extracellular acidic environment and an intracellular mildly alkaline environment induced by carbonic anhydrase 9 (CA9) play a critical role in self‐renewal, invasion, migration, and drug resistance of cancer stem cells (CSCs) within hy…
View article: Anomaly Detection in Ground Moving Target Trajectories via Chan-Taylor Collaborative Localization
Anomaly Detection in Ground Moving Target Trajectories via Chan-Taylor Collaborative Localization Open
To address the limitations in positioning accuracy and environmental adaptability of vibration-aware target monitoring systems, an enhanced TDOA acoustic source localization method based on Chan-Taylor collaborative algorithm is proposed i…
View article: Hydroxyethyl starch conjugates co-assembled nanoparticles promote photodynamic therapy and antitumor immunity by inhibiting antioxidant systems
Hydroxyethyl starch conjugates co-assembled nanoparticles promote photodynamic therapy and antitumor immunity by inhibiting antioxidant systems Open
View article: Protective Effects of Isoliquiritigenin and Licochalcone B on the Immunotoxicity of BDE-47: Antioxidant Effects Based on the Activation of the Nrf2 Pathway and Inhibition of the NF-κB Pathway
Protective Effects of Isoliquiritigenin and Licochalcone B on the Immunotoxicity of BDE-47: Antioxidant Effects Based on the Activation of the Nrf2 Pathway and Inhibition of the NF-κB Pathway Open
2,2′,4,4′-Tetrabrominated biphenyl ether (BDE-47) is a polybrominated diphenyl ether (PBDE) homologue that is ubiquitous in biological samples and highly toxic to humans and other organisms. Prior research has confirmed that BDE-47 can ind…
View article: Hyperbaric oxygen: a multifaceted approach in cancer therapy
Hyperbaric oxygen: a multifaceted approach in cancer therapy Open
As one of the fundamental characteristics of solid tumors, hypoxia promotes tumor initiation and progression, induces tumor sternness, and leads to an abundant extracellular matrix (ECM), immunosuppression, and abnormal oxidative stress le…
View article: Hyperbaric Oxygen Activates Enzyme‐Driven Cascade Reactions for Cooperative Cancer Therapy and Cancer Stem Cells Elimination
Hyperbaric Oxygen Activates Enzyme‐Driven Cascade Reactions for Cooperative Cancer Therapy and Cancer Stem Cells Elimination Open
Tumor starvation induced by intratumor glucose depletion emerges as a promising strategy for anticancer therapy. However, its antitumor potencies are severely compromised by intrinsic tumor hypoxia, low delivery efficiencies, and undesired…
View article: A novel lonidamine derivative targeting mitochondria to eliminate cancer stem cells by blocking glutamine metabolism
A novel lonidamine derivative targeting mitochondria to eliminate cancer stem cells by blocking glutamine metabolism Open
Cancer stem cells (CSCs) have been blamed as the main culprit of tumor initiation, progression, metastasis, chemoresistance, and recurrence. However, few anti-CSCs agents have achieved clinical success so far. Here we report a novel deriva…
View article: Optimization of Evaporation and Condensation Architectures for Solar-Driven Interfacial Evaporation Desalination
Optimization of Evaporation and Condensation Architectures for Solar-Driven Interfacial Evaporation Desalination Open
Solar-driven interfacial evaporation is an ideal technology for seawater desalination, and the corresponding system is mainly composed of a solar evaporator and a condensing collector. The traditional scheme focuses on the evaporation effi…
View article: Precise Depleting Fibrin and Modulating Tumor Mechanics with Hydroxyethyl Starch-Based Smart Nanomedicine for Enhanced Antitumor Efficacy
Precise Depleting Fibrin and Modulating Tumor Mechanics with Hydroxyethyl Starch-Based Smart Nanomedicine for Enhanced Antitumor Efficacy Open
View article: Tumor-specific activatable biopolymer nanoparticles stabilized by hydroxyethyl starch prodrug for self-amplified cooperative cancer therapy
Tumor-specific activatable biopolymer nanoparticles stabilized by hydroxyethyl starch prodrug for self-amplified cooperative cancer therapy Open
Rationale: Chemodynamic therapy (CDT) is an emerging tumor-specific therapeutic strategy. However, the anticancer activity of CDT is impeded by the insufficient Fenton catalytic efficiency and the high concentration of glutathione (…
View article: Hyperbaric Oxygen Boosts PD‐1 Antibody Delivery and T Cell Infiltration for Augmented Immune Responses Against Solid Tumors
Hyperbaric Oxygen Boosts PD‐1 Antibody Delivery and T Cell Infiltration for Augmented Immune Responses Against Solid Tumors Open
Aberrant mechanical properties and immunosuppression are the two key factors that limit the antitumor efficacy of T cell immune checkpoint blockade inhibitors, e.g., programmed cell death‐1 antibody (PD‐1 Ab), against solid tumors in the c…
View article: Intensity modulation based optical proximity optimization for the maskless lithography
Intensity modulation based optical proximity optimization for the maskless lithography Open
The undesirable optical proximity effect (OPE) that appeared in the digital micro-mirrors device (DMD) based maskless lithography directly influences the final exposure pattern and decreases the lithography quality. In this manuscript, a c…
View article: Dose-Modulated Maskless Lithography for the Efficient Fabrication of Compound Eyes With Enlarged Field-of-View
Dose-Modulated Maskless Lithography for the Efficient Fabrication of Compound Eyes With Enlarged Field-of-View Open
In this paper, a method of dose-modulated maskless lithography (DMML) with high efficiency for the fabrication of a special compound-eyes array with enlarged field-of-view is proposed. Before the fabrication process, practical measurements…