Qing Chen
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View article: Macrophages are the target cells of genotype VII Newcastle disease virus and promote the infection and apoptosis of chicken splenic T cells
Macrophages are the target cells of genotype VII Newcastle disease virus and promote the infection and apoptosis of chicken splenic T cells Open
View article: Construction and validation of a prediction model for developing type 2 diabetes mellitus in patients with chronic obstructive pulmonary disease
Construction and validation of a prediction model for developing type 2 diabetes mellitus in patients with chronic obstructive pulmonary disease Open
Background Type 2 diabetes mellitus (T2DM) is a common comorbidity of chronic obstructive pulmonary disease (COPD), which significantly increases the risk of rehospitalization and mortality in patients with COPD. Therefore, the purpose of …
View article: Astragalin promotes HSCs ferroptosis through NCOA4 mediated ferritinophagy to alleviate liver fibrosis in zebrafish and mice
Astragalin promotes HSCs ferroptosis through NCOA4 mediated ferritinophagy to alleviate liver fibrosis in zebrafish and mice Open
Liver fibrosis is pathological progression of chronic liver disease. Recent research has focused on the activation of hepatic stellate cells (HSCs), highlighting their potential as targets for mitigating fibrosis. While herbal medicines an…
View article: Development and characterization of a pseudovirus system for human Aichi virus: in vitro and in vivo analysis
Development and characterization of a pseudovirus system for human Aichi virus: in vitro and in vivo analysis Open
View article: Temporal Trends of Polycystic Ovary Syndrome Burden in the East and Southeast Asia from 1990 to 2021: An Analysis from the Global Burden of Disease Study 2021
Temporal Trends of Polycystic Ovary Syndrome Burden in the East and Southeast Asia from 1990 to 2021: An Analysis from the Global Burden of Disease Study 2021 Open
The increasing burden of PCOS has become a public health problem in the East and Southeast Asia region. The development of appropriate health measures and strategies to prevent and manage PCOS has become extremely urgent.
View article: Macrophages are the target cells for genotype VII Newcastle disease virus and promote the infection and apoptosis of chicken splenic T cells
Macrophages are the target cells for genotype VII Newcastle disease virus and promote the infection and apoptosis of chicken splenic T cells Open
Infection with genotype VII Newcastle disease virus (NDV) poses a significant threat to poultry health, characterized by severe damage to immune organs such as lymphocyte depletion. However, the precise mechanisms underlying this phenomeno…
View article: SAMD4A inhibits abdominal aortic aneurysm development and VSMC phenotypic transformation through targeting KDM2B
SAMD4A inhibits abdominal aortic aneurysm development and VSMC phenotypic transformation through targeting KDM2B Open
SAMD4A inhibits AAA development and VSMC phenotypic transformation by targeting KDM2B. This work highlights the potential of SAMD4A as a new therapeutic option to prevent AAA formation.
View article: A TaqMan probe-based multiplex real-time quantitative pcr for simultaneous detection of kobuvirus, parechovirus B, rosavirus B, and hunnivirus carried by murine rodents and shrews
A TaqMan probe-based multiplex real-time quantitative pcr for simultaneous detection of kobuvirus, parechovirus B, rosavirus B, and hunnivirus carried by murine rodents and shrews Open
View article: Exploring public attitudes of continuing care retirement communities in China: a sentiment analysis of China’s social media Weibo
Exploring public attitudes of continuing care retirement communities in China: a sentiment analysis of China’s social media Weibo Open
Introduction The traditional family responsibility system faces challenges as China undergoes rapid demographic shifts with an increasingly older population. Recognizing the potential of market-driven senior care, Continuing Care Retiremen…
View article: FEASIBILITY OF EFFICIENT COD REMOVAL OF SIMULATED DOMESTIC SEWAGE FROM INLAND SHIPS IN SINGLE-STAGE CSTR UNDER MICROAEROBIC CONDITION
FEASIBILITY OF EFFICIENT COD REMOVAL OF SIMULATED DOMESTIC SEWAGE FROM INLAND SHIPS IN SINGLE-STAGE CSTR UNDER MICROAEROBIC CONDITION Open
View article: Examining the influence of port ship activities on pollutant emissions in port environments
Examining the influence of port ship activities on pollutant emissions in port environments Open
There is a direct and close relationship between ship emissions in port waters and the operational status of the ships. Precisely identifying the operational status of ships in port waters and thoroughly exploring the specific relationship…
View article: Trimethylamine Induced Chronic Kidney Injury by Activating the ZBP1-NLRP3 Inflammasome Pathway
Trimethylamine Induced Chronic Kidney Injury by Activating the ZBP1-NLRP3 Inflammasome Pathway Open
Trimethylamine N-oxide (TMAO), a bioactive metabolite of gut microbes, plays a pivotal role in the pathogenesis of kidney diseases by activating programmed cell death (PCD) pathways. However, whether trimethylamine (TMA) contributes to chr…
View article: A panoramic view of the molecular epidemiology, evolution, and cross-species transmission of rosaviruses
A panoramic view of the molecular epidemiology, evolution, and cross-species transmission of rosaviruses Open
Rosavirus is a newly discovered member of the family Picornaviridae that was initially detected in wild rodents and subsequently in children with diarrhoea. Nevertheless, there is a significant gap in our understanding of the geographical …
View article: The trend analysis of HIV and other sexually transmitted infections among the elderly aged 50 to 69 years from 1990 to 2030
The trend analysis of HIV and other sexually transmitted infections among the elderly aged 50 to 69 years from 1990 to 2030 Open
Overall, despite the evident decline in incidence, mortality rates, and DALYs, the prevalence of HIV and other STI among the elderly is rising, and both demonstrated significant trend variations across different ages, genders, SDI regions,…
View article: Chondroitin Sulfate‐Modified Hydroxyapatite for Caspase‐1 Activated Induced Pyroptosis through Ca Overload/ER Stress/STING/IRF3 Pathway in Colorectal Cancer
Chondroitin Sulfate‐Modified Hydroxyapatite for Caspase‐1 Activated Induced Pyroptosis through Ca Overload/ER Stress/STING/IRF3 Pathway in Colorectal Cancer Open
Immune checkpoint inhibitors, are the fourth most common therapeutic tool after surgery, chemotherapy, and radiotherapy for colorectal cancer (CRC). However, only a small proportion (≈5%) of CRC patients, those with “hot” (immuno‐activated…
View article: Surface engineering of highly ordered <scp>Bi<sub>2</sub>S<sub>3</sub></scp> film with open channels toward high‐performance broadband photodetection
Surface engineering of highly ordered <span>Bi<sub>2</sub>S<sub>3</sub></span> film with open channels toward high‐performance broadband photodetection Open
The highly ordered film assembled by regularly 1D nanostructures has potential prospects in electronic, photoelectronic and other fields because of its excellent light‐trapping effect and electronic transport property. However, the control…
View article: Changes in decision‐making function in patients with subacute mild traumatic brain injury
Changes in decision‐making function in patients with subacute mild traumatic brain injury Open
Although awareness regarding patients with mild traumatic brain injury has increased, they have not received sufficient attention in clinics; hence, many patients still experience only partial recovery. Deficits in decision‐making function…
View article: Patterns and Influencing Factors of Air Pollution at a Southeast Chinese City
Patterns and Influencing Factors of Air Pollution at a Southeast Chinese City Open
Ambient air pollution is a pressing global environmental problem. To identify the source of air pollution and manage air quality in urban areas, the patterns of air pollutants under different traffic conditions and the impact of weather on…
View article: Role of Macrophages in the Pathogenesis of Genotype VII Newcastle Disease Virus in Chickens
Role of Macrophages in the Pathogenesis of Genotype VII Newcastle Disease Virus in Chickens Open
Long-term evolution of Newcastle disease virus (NDV) results in substantial alteration in viral pathogenesis. NDVs of genotype VII, a late genotype, show marked tropism to lymphoid tissues, especially to macrophages in chickens. However, t…
View article: Comparison of syndrome differentiation and treatment system between Huangdi Neijing and Treatise on Cold Damage
Comparison of syndrome differentiation and treatment system between Huangdi Neijing and Treatise on Cold Damage Open
View article: The trends in death of primary liver cancer caused by specific etiologies worldwide: results from the Global Burden of Disease Study 2019 and implications for liver cancer management
The trends in death of primary liver cancer caused by specific etiologies worldwide: results from the Global Burden of Disease Study 2019 and implications for liver cancer management Open
Background: Over past decades, epidemiological patterns of liver cancer (LC) have changed dramatically. The Global Burden Of Disease (GBD) study provides an opportunity to tracking the progress in cancer control with its annual updated rep…
View article: Factors associated with influenza vaccination coverage and willingness in the elderly with chronic diseases in Shenzhen, China
Factors associated with influenza vaccination coverage and willingness in the elderly with chronic diseases in Shenzhen, China Open
Elderly individuals with chronic illnesses are more prone to get influenza. We aimed to investigate the factors associated with influenza coverage and willingness in chronic disease patients aged ≥60 years in Longhua district, Shenzhen Cit…
View article: Adverse Events of Vaccination against Hepatitis B Virus in Post-Marketing Surveillance from 2005 to 2017 in Guangdong Province, China
Adverse Events of Vaccination against Hepatitis B Virus in Post-Marketing Surveillance from 2005 to 2017 in Guangdong Province, China Open
The present study focused on the adverse events following the vaccination against hepatitis B virus (HBV) in the Guangdong Province of China between 2005 and 2017. In total, more than 88 million doses of HBV vaccine were administered in th…
View article: Foreign gene expression attenuates a virulent Newcastle disease virus in chickens
Foreign gene expression attenuates a virulent Newcastle disease virus in chickens Open
View article: Association between intimate partner violence and prenatal anxiety and depression in pregnant women: a cross-sectional survey during the COVID-19 epidemic in Shenzhen, China
Association between intimate partner violence and prenatal anxiety and depression in pregnant women: a cross-sectional survey during the COVID-19 epidemic in Shenzhen, China Open
Objectives Intimate partner violence (IPV) against women remains a major global public health problem with harmful consequences for individuals and society. People’s lifestyles have been greatly affected by the COVID-19 pandemic. This stud…
View article: COVID-19 vaccine acceptance among cold-chain workers in Shenzhen, China: A cross-sectional survey
COVID-19 vaccine acceptance among cold-chain workers in Shenzhen, China: A cross-sectional survey Open
Given the high level of exposure to SARS-CoV-2, cold-chain workers are considered priority vaccination groups. To date, many studies have reported on the willingness within distinct populations to be vaccinated against COVID-19, whereas it…
View article: Epidemiology and genetic characteristics of murine kobuvirus from fecal samples of Rattus losea, Rattus tanezumi and Rattus norvegicus in Southern China
Epidemiology and genetic characteristics of murine kobuvirus from fecal samples of Rattus losea, Rattus tanezumi and Rattus norvegicus in Southern China Open
Background: Most recently, murine kobuvirus (MuKV), a novel recognized member of the family Picornaviridae, has been initially identified from fecal samples of Rattus norvegicus in China. The circulation of MuKV from other murine rodent sp…
View article: Ungulate bocaparvovirus 4 and rodent bocavirus are different genotypes of the same species of virus
Ungulate bocaparvovirus 4 and rodent bocavirus are different genotypes of the same species of virus Open
Bocaviruses are associated with many human infectious diseases, such as respiratory tract infections, gastroenteritis, and hepatitis. Rats are known to be reservoirs of bocaviruses, including rodent bocavirus and rat bocavirus. Recently, u…
View article: Supplementary Material for: Association of Intravenous Tirofiban with Functional Outcomes in Acute Ischemic Stroke Patients with Acute Basilar Artery Occlusion Receiving Endovascular Thrombectomy
Supplementary Material for: Association of Intravenous Tirofiban with Functional Outcomes in Acute Ischemic Stroke Patients with Acute Basilar Artery Occlusion Receiving Endovascular Thrombectomy Open
Introduction: The aim of this study was to test the hypothesis that intravenous tirofiban improves functional outcomes without promoting the risk of intracranial hemorrhage (ICH) in stroke secondary to basilar artery occlusio…
View article: Spatiotemporal Evolution and Genesis of the Late Ordovician—Early Silurian Marine Euxinia in Northeastern Upper Yangtze Basin, South China
Spatiotemporal Evolution and Genesis of the Late Ordovician—Early Silurian Marine Euxinia in Northeastern Upper Yangtze Basin, South China Open
Marine redox conditions and their dynamic changes were a major factor that controlled the formation of black shale and caused the late Ordovician marine extinction in the Upper Yangtze Basin (South China). However, the spatiotemporal varia…