Qirui Wang
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View article: Stimuli‐Responsive CuFeTe <sub>2</sub> Nanosheets for Amplified Cuproptosis/Ferroptosis in Triple‐Negative Breast Cancer Therapy
Stimuli‐Responsive CuFeTe <sub>2</sub> Nanosheets for Amplified Cuproptosis/Ferroptosis in Triple‐Negative Breast Cancer Therapy Open
Triple‐negative breast cancer (TNBC) exhibits high copper and iron uptake, making cuproptosis and ferroptosis promising therapeutic strategies. However, their efficacy is limited by TNBC's intrinsic antioxidant defences. Herein, CuFeTe 2 n…
View article: Assessment of the Impact of the Introduction of BIM on the Core Competitiveness of Large Building Construction Companies
Assessment of the Impact of the Introduction of BIM on the Core Competitiveness of Large Building Construction Companies Open
In the context of the digital transformation of the construction industry, this study examines the impact of Building Information Modelling (BIM) technology on the core competitiveness of large building construction enterprises. Through li…
View article: METTL3-mediated m&lt;sup&gt;6&lt;/sup&gt;A modification of pri-miRNA-31 promotes hypertrophic scar progression
METTL3-mediated m<sup>6</sup>A modification of pri-miRNA-31 promotes hypertrophic scar progression Open
Hypertrophic scar (HS) is a pathological scar characterized by excessive dermal fibrosis. Aberrant m 6A modification patterns have been identified in HS; however, the expression of the methyltransferase, along with its function and molecul…
View article: Surface-Modification Strategy to Produce Highly Anticorrosive Ti3C2Tx MXene-Based Polymer Composite Coatings: A Mini-Review
Surface-Modification Strategy to Produce Highly Anticorrosive Ti3C2Tx MXene-Based Polymer Composite Coatings: A Mini-Review Open
MXenes are a group of novel two-dimensional (2D) materials with merits such as large specific surface area, abundant surface-functional groups, high chemical activity, excellent mechanical properties, high hydrophilicity, and good compatib…
View article: ECOSTRESS-Based Analysis of Diurnal Urban Heat Island Intensity and Thermal Dynamics Across LCZ in Six Chinese Cities With Diverse Terrain and Elevation
ECOSTRESS-Based Analysis of Diurnal Urban Heat Island Intensity and Thermal Dynamics Across LCZ in Six Chinese Cities With Diverse Terrain and Elevation Open
Urban surface heterogeneity leads to significant variability in temperature distribution, complicating the measurement of surface urban heat island intensity (SUHII) and the development of thermal stress mitigation strategies. This study u…
View article: Study on the Effects of CeO2 on the Micro-Structure and Wear Resistance of CuCrZr Plasma Cladding Coatings
Study on the Effects of CeO2 on the Micro-Structure and Wear Resistance of CuCrZr Plasma Cladding Coatings Open
The electromagnetic railgun, a novel kinetic energy weapon, has found utility in military operations due to its enhanced safety features and superior precision. This study investigates the enhancement of wear resistance in CuCrZr rails thr…
View article: Research on damping defects of composite insulator core rods
Research on damping defects of composite insulator core rods Open
Infrared thermal imaging detection is an effective method to detect faults in composite insulators, but various reasons can cause abnormal heating of composite insulators. Therefore, distinguishing abnormal heating caused by different reas…
View article: Bacteria/Nanozyme Composites: New Therapeutics for Disease Treatment
Bacteria/Nanozyme Composites: New Therapeutics for Disease Treatment Open
Bacterial therapy is recognized as a cost‐effective treatment for several diseases. However, its development is hindered by limited functionality, weak inherent therapeutic effects, and vulnerability to harsh microenvironmental conditions,…
View article: Improved estimation of lake greenhouse gas emissions in China based on nutrients and potential benefits from eutrophication controls
Improved estimation of lake greenhouse gas emissions in China based on nutrients and potential benefits from eutrophication controls Open
Lakes are important natural sources of greenhouse gases (GHGs) to the atmosphere, and their nutrient status is a significant driver affecting GHGs production and emission. Nevertheless, when estimating GHGs emissions at regional or nationa…
View article: Stimuli-Responsive Delivery Systems for Intervertebral Disc Degeneration
Stimuli-Responsive Delivery Systems for Intervertebral Disc Degeneration Open
As a major cause of low back pain, intervertebral disc degeneration is an increasingly prevalent chronic disease worldwide that leads to huge annual financial losses. The intervertebral disc consists of the inner nucleus pulposus, outer an…
View article: Discovery of Novel Potent and Fast BTK PROTACs for the Treatment of Osteoclasts-Related Inflammatory Diseases
Discovery of Novel Potent and Fast BTK PROTACs for the Treatment of Osteoclasts-Related Inflammatory Diseases Open
Bruton's tyrosine kinase (BTK) is an attractive target in inflammatory and autoimmune diseases. However, the effectiveness of BTK inhibitors is limited by side effects and drug resistance. In this study, we report the development of novel …
View article: An investigative study of persistent symptoms and menstrual abnormalities in female students infected with COVID-19 at a university in Chongqing, China
An investigative study of persistent symptoms and menstrual abnormalities in female students infected with COVID-19 at a university in Chongqing, China Open
In order to investigate the general conditions of female students infected with COVID-19 (2019 Novel Coronavirus) in a college in Chongqing, China, and the impacts of persistent symptoms on female menstruation, we conducted a questionnaire…
View article: Ampelopsis japonica aqueous extract improves ovulatory dysfunction in PCOS by modulating lipid metabolism
Ampelopsis japonica aqueous extract improves ovulatory dysfunction in PCOS by modulating lipid metabolism Open
Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine and metabolic disorder that is closely associated with the proliferation and apoptosis of ovarian granulosa cells (GCs). Ampelopsis japonica (AJ) is the dried tuberous root o…
View article: Clinical values of circulating tumor cells count in localized renal cell carcinoma
Clinical values of circulating tumor cells count in localized renal cell carcinoma Open
Surgical treatment can remarkably reduce the number of CTCs in patients, and CTC counts can also play a role in monitoring tumor load and predicting prognosis in renal cancer.
View article: Mirror training device improves dental students’ performance on virtual simulation dental training system
Mirror training device improves dental students’ performance on virtual simulation dental training system Open
Introduction Clinical practice of dentistry entails the use of indirect vision using a dental mirror. The Mirrosistant is a device that helps dental students become proficient with use of indirect vision mirror operation. This study aimed …
View article: Main Problems Faced by Biomass Coupling Power Generation Metering
Main Problems Faced by Biomass Coupling Power Generation Metering Open
Carry out in-depth research on the electricity metering project of the biomass gasification coupled power generation project of Hubei Huadian Xiangyang Power Generation Co., Ltd., and upgrade the existing metering capacity based on the req…
View article: Identification and validation of a TTN-associated immune prognostic model for skin cutaneous melanoma
Identification and validation of a TTN-associated immune prognostic model for skin cutaneous melanoma Open
TTN is the most commonly mutated gene in skin cutaneous melanoma (SKCM). Tumor mutational burden (TMB) can generate new antigens that regulate the recognition of T cells, which will significantly affect the prognosis of patients. The TTN g…
View article: A “signal-off” photoelectrochemical aptasensing for ATP based on Zinc Oxide/graphene nanocomposite prepared by graphene oxide’s catalytic decomposition performance towards zinc sulfateat low-temperature
A “signal-off” photoelectrochemical aptasensing for ATP based on Zinc Oxide/graphene nanocomposite prepared by graphene oxide’s catalytic decomposition performance towards zinc sulfateat low-temperature Open
Optimization synthesis of semiconductor nanostructures with controlled crystallinity, size and morphology for improving inherent property of photoactive materials is crucial for achieving excellent PEC biosensor. Here, we tried to synthesi…
View article: Two-dimensional nanovermiculite and polycaprolactone electrospun fibers composite scaffolds promoting diabetic wound healing
Two-dimensional nanovermiculite and polycaprolactone electrospun fibers composite scaffolds promoting diabetic wound healing Open
Background Promoting diabetic wound healing is still a challenge, and angiogenesis is believed to be essential for diabetic wound healing. Vermiculite is a natural clay material that is very easy to obtain and exhibits excellent properties…
View article: The Complete Cloroplast Genomes of Tetrastigma Hemsleyanum (Vitaceae) from Different Regions of China: Molecular Structure, Comparative Analysis and Development of DNA Barcodes for its Geographical Origin Discrimination
The Complete Cloroplast Genomes of Tetrastigma Hemsleyanum (Vitaceae) from Different Regions of China: Molecular Structure, Comparative Analysis and Development of DNA Barcodes for its Geographical Origin Discrimination Open
Background Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-i…
View article: The complete chloroplast genomes of Tetrastigma hemsleyanum (Vitaceae) from different regions of China: Molecular structure, comparative analysis and development of DNA barcodes for its geographical origin discrimination
The complete chloroplast genomes of Tetrastigma hemsleyanum (Vitaceae) from different regions of China: Molecular structure, comparative analysis and development of DNA barcodes for its geographical origin discrimination Open
Background Tetrastigma hemsleyanum is a valuable traditional Chinese medicinal plant widely distributed in the subtropical areas of China. It belongs to the Cayratieae tribe, family Vitaceae, and exhibited significant anti-tumor and anti-i…
View article: Complete chloroplast genome of Stephania tetrandra (Menispermaceae) from Zhejiang Province: insights into molecular structures, comparative genome analysis, mutational hotspots and phylogenetic relationships
Complete chloroplast genome of Stephania tetrandra (Menispermaceae) from Zhejiang Province: insights into molecular structures, comparative genome analysis, mutational hotspots and phylogenetic relationships Open
Background The Stephania tetrandra S. Moore ( S. tetrandra ) is a medicinal plant belonging to the family Menispermaceae that has high medicinal value and is well worth doing further exploration. The wild resources of S. tetrandra were wid…
View article: Hyoscyamus labiatus sp. nov. (Solanaceae: Hyoscyameae) from Henan, China: implications for the delimitation of Hyoscyamus
Hyoscyamus labiatus sp. nov. (Solanaceae: Hyoscyameae) from Henan, China: implications for the delimitation of Hyoscyamus Open
Background Hyoscyamus , the largest genus in the tribe Hyoscyameae, harbors more than 20 species. Although the monophyly of Hyoscyamus is supported by both morphological and molecular phylogenetic studies, the delimitation of Hyoscyamus ha…
View article: In vitro and in vivo analysis of monotherapy and dual therapy with ethyl caffeate and fluconazole on virulence factors of Candida albicans and systemic candidiasis
In vitro and in vivo analysis of monotherapy and dual therapy with ethyl caffeate and fluconazole on virulence factors of Candida albicans and systemic candidiasis Open
EC exhibits a moderate antifungal potential but can be a strong synergist with FLU against C. albicans, highlighting the potential of EC in clinical antifungal therapy as a sensitiser.
View article: Tumor Associated Macrophages, as the Dominant Immune Cells, Are an Indispensable Target for Immunologically Cold Tumor—Glioma Therapy?
Tumor Associated Macrophages, as the Dominant Immune Cells, Are an Indispensable Target for Immunologically Cold Tumor—Glioma Therapy? Open
Tumor microenvironment (TME) is the cornerstone of the occurrence, development, invasion and diffusion of the malignant central nerve system (CNS) tumor, glioma. As the largest number of inflammatory cells in glioma TME, tumor associated m…
View article: Effect of Heat Treatment on Microstructure and Tensile Property of Ti-6Al-6V-2Sn Alloy
Effect of Heat Treatment on Microstructure and Tensile Property of Ti-6Al-6V-2Sn Alloy Open
The microstructure and tensile properties of Ti-6Al-6V-2Sn alloy heat-treated at different solution and aging temperatures has been systematically investigated. Specimens were solution-treated at 970 °C (above the β transus) and 920 °C (be…