Qiting Zeng
YOU?
Author Swipe
View article: DCC-2036 induces repolarization of TAMs to M1 type and enhances CD8+ T cell immunity in TNBC
DCC-2036 induces repolarization of TAMs to M1 type and enhances CD8+ T cell immunity in TNBC Open
Therapies for triple-negative breast cancer (TNBC) still need innovative approaches, while repolarizing tumor-associated macrophages (TAMs) may offer a breakthrough in the targeted therapy and immunotherapy of TNBC. In this study, our grou…
View article: Enhancing immunotherapy efficacy in colorectal cancer: targeting the FGR-AKT-SP1-DKK1 axis with DCC-2036 (Rebastinib)
Enhancing immunotherapy efficacy in colorectal cancer: targeting the FGR-AKT-SP1-DKK1 axis with DCC-2036 (Rebastinib) Open
This research demonstrates that DCC-2036 (Rebastinib), a potent third-generation tyrosine kinase inhibitor (TKI), effectively suppresses tumor growth in colorectal cancer (CRC) models with functional immune systems. The findings underscore…
View article: Recent advances in hematopoietic cell kinase in cancer progression: Mechanisms and inhibitors
Recent advances in hematopoietic cell kinase in cancer progression: Mechanisms and inhibitors Open
Hematopoietic cell kinase (Hck), a non-receptor tyrosine kinase belonging to the Src kinase family, is intricately linked to the pathogenesis of numerous human diseases, with a particularly pronounced association with cancer. Hck not only …
View article: Metabolism of asparagine in the physiological state and cancer
Metabolism of asparagine in the physiological state and cancer Open
View article: The emerging roles of metabolism in the crosstalk between breast cancer cells and tumor-associated macrophages
The emerging roles of metabolism in the crosstalk between breast cancer cells and tumor-associated macrophages Open
Breast cancer is the most common cancer affecting women worldwide. Investigating metabolism in breast cancer may accelerate the exploitation of new therapeutic options for immunotherapies. Metabolic reprogramming can confer breast cancer c…