Qiuping Wu
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View article: Inside Front Cover: Functional Nanosensor‐Integrated System Based on Molecularly Imprinted Quartz Crystal Microbalance for Rapid In Situ Detection of 3‐Chloro‐1,2‐Propanediol in Paper‐Based Food Contact Materials
Inside Front Cover: Functional Nanosensor‐Integrated System Based on Molecularly Imprinted Quartz Crystal Microbalance for Rapid In Situ Detection of 3‐Chloro‐1,2‐Propanediol in Paper‐Based Food Contact Materials Open
View article: IL4I1 overexpression protects against nonalcoholic fatty liver disease in part by inhibiting the AKT/FOXO1 pathway-mediated Th17 cell differentiation
IL4I1 overexpression protects against nonalcoholic fatty liver disease in part by inhibiting the AKT/FOXO1 pathway-mediated Th17 cell differentiation Open
Nonalcoholic fatty liver disease (NAFLD) has posed a huge threat to public health globally, but there are currently no approved drugs available. Growing evidence has proved the close association between increased Th17 cells and NAFLD progr…
View article: A trade-off mechanism underpins the evolution of a young two-gene sex-determining system in plants
A trade-off mechanism underpins the evolution of a young two-gene sex-determining system in plants Open
Sexual systems in animals and plants are remarkably diverse, with dioecy having evolved independently in numerous lineages. In plants, dioecy often evolved more recently than in the best-studied animal systems, making plants especially imp…
View article: Functional Nanosensor‐Integrated System Based on Molecularly Imprinted Quartz Crystal Microbalance for Rapid In Situ Detection of 3‐Chloro‐1,2‐Propanediol in Paper‐Based Food Contact Materials
Functional Nanosensor‐Integrated System Based on Molecularly Imprinted Quartz Crystal Microbalance for Rapid In Situ Detection of 3‐Chloro‐1,2‐Propanediol in Paper‐Based Food Contact Materials Open
To address the limitations of traditional methods in detecting 3‐chloro‐1,2‐propanediol (3‐MCPD) in food contact materials (FCMs)—notably complex operations, prolonged detection cycles, and low sensitivity—this study introduces a novel Mol…
View article: Dietary kelp meal (Thallus laminariae) improves the immunity of hybrid snakeheads under ammonia stress
Dietary kelp meal (Thallus laminariae) improves the immunity of hybrid snakeheads under ammonia stress Open
This study determined the effect of dietary kelp meal (KM) on metabolism of the hybrid snakeheads (Channa maculatus ♀ × Channa argus ♂), and the spatiotemporal changes in their resistance to ammonia stress, including survival rate, histopa…
View article: A195V mutation identified in sudden cardiac death decreases membrane localization and activation current density and abolishes cAMP sensitivity of HCN4 channels
A195V mutation identified in sudden cardiac death decreases membrane localization and activation current density and abolishes cAMP sensitivity of HCN4 channels Open
Mutation A195V in hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) channel was identified to be genetically associated with sudden unexplained nocturnal death syndrome (SUNDS) and sudden infant death syndrome (SIDS) by …
View article: The characteristics of thoracic aortic dissection in autopsy-diagnosed individuals: An autopsy study
The characteristics of thoracic aortic dissection in autopsy-diagnosed individuals: An autopsy study Open
Thoracic aortic dissection (TAD) is the most common cause of sudden cardiac death associated with aortic diseases. The age of TAD victims in forensic studies is significantly younger than hospitalized patients with TAD, while only a few st…
View article: Sudden Cardiac Death and Cardiac Sodium Channel Diseases
Sudden Cardiac Death and Cardiac Sodium Channel Diseases Open
Sudden cardiac death (SCD), accounting for a substantial part of the forensic autopsy, is a leading cause of mortality worldwide. Lethal arrhythmia due to sodium channel diseases is recognized as one of the most prevalent etiologies of SCD…
View article: Comparative Chloroplast Genomics and Phylogenetic Analysis of Thuniopsis and Closely Related Genera within Coelogyninae (Orchidaceae)
Comparative Chloroplast Genomics and Phylogenetic Analysis of Thuniopsis and Closely Related Genera within Coelogyninae (Orchidaceae) Open
The genus Thuniopsis was recently proposed for a rare orchid species T. cleistogama formerly classified in the genus Thunia . The relationships between Thuniopsis and its related genera have not yet been conclusively resolved. Recognition …
View article: Tau N-Terminal Inserts Regulate Tau Liquid-Liquid Phase Separation and Condensates Maturation in a Neuronal Cell Model
Tau N-Terminal Inserts Regulate Tau Liquid-Liquid Phase Separation and Condensates Maturation in a Neuronal Cell Model Open
The microtubule-associated protein tau can undergo liquid–liquid phase separation (LLPS) to form membraneless condensates in neurons, yet the underlying molecular mechanisms and functions of tau LLPS and tau droplets remain to be elucidate…
View article: PF-06409577 Activates AMPK Signaling and Inhibits Osteosarcoma Cell Growth
PF-06409577 Activates AMPK Signaling and Inhibits Osteosarcoma Cell Growth Open
Osteosarcoma (OS) is a common primary bone malignancy. We here investigated the potential activity of PF-06409577, a novel, potent, and direct activator of AMP-activated protein kinase (AMPK), against human OS cells. In established (U2OS, …
View article: <strong>Reconsideration of the taxonomic status of <em>Bulbophyllum obtusangulum</em> (Orchidaceae) from southern China</strong>
<strong>Reconsideration of the taxonomic status of <em>Bulbophyllum obtusangulum</em> (Orchidaceae) from southern China</strong> Open
Bulbophyllum obtusangulum Z.H. Tsi has long been treated as a synonymy of B. lepidum (Blume) J.J. Sm., which is broadly distributed in Southeast Asia. In this paper, based on a re-evaluation of morphological characters and critical study o…
View article: Fisetin inhibits tau aggregation by interacting with the protein and preventing the formation of β-strands
Fisetin inhibits tau aggregation by interacting with the protein and preventing the formation of β-strands Open
View article: Study of the association of interferon-γ gene polymorphisms and Th1/Th2 balance in tuberculosis susceptibility.
Study of the association of interferon-γ gene polymorphisms and Th1/Th2 balance in tuberculosis susceptibility. Open
An AA genotype with IFN-γ (+874 T/A) is a susceptible genotype for tuberculosis. The mechanism may be related to the imbalance of Th1/Th2 which is more likely to occur in patients with AA genotype. This can lead to a decline in immune func…
View article: Expression of a plastid-localized sugar transporter in the suspensor is critical to embryogenesis
Expression of a plastid-localized sugar transporter in the suspensor is critical to embryogenesis Open
Plant growth and development rely on sugar transport between source and sink cells and between different organelles. The plastid-localized sugar transporter GLUCOSE-6-PHOSPHATE TRANSLOCATER1 (GPT1) is an essential gene in Arabidopsis (Arab…
View article: Characterization of the complete chloroplast genome of <i>Coelogyne fimbriata</i> (Orchidaceae)
Characterization of the complete chloroplast genome of <i>Coelogyne fimbriata</i> (Orchidaceae) Open
Coelogyne fimbriata has been classified as a national second-class protected orchid species in China. In this study, we report and characterize the complete chloroplast (cp) genome sequence of C. fimbriata in an effort…
View article: The complete chloroplast genome of <i>Pholidota yunnanensis</i> Rolfe (Orchidaceae: Coelogyninae)
The complete chloroplast genome of <i>Pholidota yunnanensis</i> Rolfe (Orchidaceae: Coelogyninae) Open
In this study, the complete chloroplast genome of Pholidota yunnanensis is presented, which represents first complete plastid genome of the genus Pholidota in the subtribe Coelogyninae. The chloroplast genome size is 159,729 …
View article: Identification and antimicrobial resistance of pathogens in neonatal septicemia in China—A meta-analysis
Identification and antimicrobial resistance of pathogens in neonatal septicemia in China—A meta-analysis Open
It is concluded that Staphylococcus, especially coagulase-negative Staphylococcus, continues to be the principal organism responsible for neonatal septicemia in China; Enterobacteriaceae are common among the Gram-negative isolates. Signifi…
View article: Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population
Critical Roles of Xirp Proteins in Cardiac Conduction and Their Rare Variants Identified in Sudden Unexplained Nocturnal Death Syndrome and Brugada Syndrome in Chinese Han Population Open
Background Sudden unexplained nocturnal death syndrome ( SUNDS ) remains an autopsy negative entity with unclear etiology. Arrhythmia has been implicated in SUNDS . Mutations/deficiencies in intercalated disc components have been shown to …
View article: Brugada syndrome: a fatal disease with complex genetic etiologies – still a long way to go
Brugada syndrome: a fatal disease with complex genetic etiologies – still a long way to go Open
Brugada syndrome (BrS) is an arrhythmogenic disorder which was first described in 1992. This disease is a channelopathy characterized by ST-segment elevations in the right precordial leads and is susceptible to sudden death. BrS is a fatal…
View article: The forensic pathological analysis of sport-related sudden cardiac death in Southern China
The forensic pathological analysis of sport-related sudden cardiac death in Southern China Open
Studies regarding sport-related sudden cardiac death (SCD) mainly focus on competitive athletes; similar data are rare in the general population, especially in China. We conducted a retrospective study (from September 1998 to August 2013) …
View article: Molecular pathological study on LRRC10 in sudden unexplained nocturnal death syndrome in the Chinese Han population
Molecular pathological study on LRRC10 in sudden unexplained nocturnal death syndrome in the Chinese Han population Open
View article: Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats
Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats Open
LMCS can improve gastric mucosa tissue repair, exert significant influences on oxidative and antioxidant enzyme activities and neutrophil infiltration.
View article: The biophysical characterization of the first SCN5A mutation R1512W identified in Chinese sudden unexplained nocturnal death syndrome
The biophysical characterization of the first SCN5A mutation R1512W identified in Chinese sudden unexplained nocturnal death syndrome Open
Increasing evidence observed in clinical phenotypes show that abrupt breathing disorders during sleep may play an important role in the pathogenesis of sudden unexplained nocturnal death syndrome (SUNDS). The reported Brugada syndrome caus…
View article: Forensic Pathological Study of 1656 Cases of Sudden Cardiac Death in Southern China
Forensic Pathological Study of 1656 Cases of Sudden Cardiac Death in Southern China Open
Sudden cardiac death (SCD) is progressively threatening the lives of young people throughout the world. We conducted a retrospective study of SCD cases identified among sudden death cases based on comprehensive autopsies and pathological e…
View article: Common Variants in Promoter of ADTRP Associate with Early-Onset Coronary Artery Disease in a Southern Han Chinese Population
Common Variants in Promoter of ADTRP Associate with Early-Onset Coronary Artery Disease in a Southern Han Chinese Population Open
The first genome-wide association study for coronary artery disease (CAD) in the Han Chinese population, we reported recently, had identified rs6903956 in gene ADTRP on chromosome 6p24.1 as a novel susceptibility locus for CAD. The risk al…