Qiushuo Zong
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View article: Climatic and Topographic Drivers of Flavonoid and Scutellarin Accumulation in Yunnan’s High-quality Erigeron breviscapus
Climatic and Topographic Drivers of Flavonoid and Scutellarin Accumulation in Yunnan’s High-quality Erigeron breviscapus Open
Erigeron breviscapus (EB), a renowned Chinese medicinal plant in Yunnan's Luxi and Shizong Counties, is rich in total flavonoids and scutellarin, but systematic studies in Luxi are limited. This study analyzed 260 cultivated EB samples, ex…
View article: Mangiferin attenuates Ang II-induced abdominal aortic aneurysm by blocking Lys591-mediated nuclear translocation of STAT3
Mangiferin attenuates Ang II-induced abdominal aortic aneurysm by blocking Lys591-mediated nuclear translocation of STAT3 Open
This study is the first to demonstrate that mangiferin inhibits AAA by targeting the STAT3-KLF5 axis to stabilize VSMC contractility and survival, placing mangiferin as a novel natural therapeutic candidate for AAA.
View article: Targeted Delivery of Nanoparticles to Blood Vessels for the Treatment of Atherosclerosis
Targeted Delivery of Nanoparticles to Blood Vessels for the Treatment of Atherosclerosis Open
Atherosclerosis is a common form of cardiovascular disease, which is one of the most prevalent causes of death worldwide, particularly among older individuals. Surgery is the mainstay of treatment for severe stenotic lesions, though the ra…
View article: Corilagin alleviates atherosclerosis by inhibiting NLRP3 inflammasome activation via the Olfr2 signaling pathway in vitro and in vivo
Corilagin alleviates atherosclerosis by inhibiting NLRP3 inflammasome activation via the Olfr2 signaling pathway in vitro and in vivo Open
Introduction Atherosclerosis, a leading cause of global cardiovascular mortality, is characterized by chronic inflammation. Central to this process is the NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome, which significantl…
View article: 241P Development and characterization of a novel DLL3-targeting antibody drug conjugate (ADC) for the treatment of solid tumors
241P Development and characterization of a novel DLL3-targeting antibody drug conjugate (ADC) for the treatment of solid tumors Open
DLL3, a type I transmembrane protein that serves as an inhibitor in the Notch pathway, is a validated target for direct therapy. It exhibits significant upregulation and abnormal expression on the cell surface in small cell lung cancer (SC…
View article: Prosthetic venous valves for chronic venous insufficiency: Advancements and future design directions
Prosthetic venous valves for chronic venous insufficiency: Advancements and future design directions Open
With the serious aging population and lifestyle changes, chronic venous insufficiency accounts for approximately 25.95% of the population, which may lead to lower limb edema and leg heaviness, as well as severe infections of skin ulcers th…
View article: Model Predictive Control of Pneumatic Artificial Muscle Antagonist Joint Angle Tracking Based on T-S Fuzzy Modelling
Model Predictive Control of Pneumatic Artificial Muscle Antagonist Joint Angle Tracking Based on T-S Fuzzy Modelling Open