Quanchang Gu
YOU?
Author Swipe
View article: Structural insights into ligand recognition and activation of human purinergic receptor P2Y14
Structural insights into ligand recognition and activation of human purinergic receptor P2Y14 Open
View article: Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1
Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1 Open
View article: Fenofibrate Recognition and G<sub>q</sub> Protein Coupling Mechanisms of the Human Cannabinoid Receptor CB1
Fenofibrate Recognition and G<sub>q</sub> Protein Coupling Mechanisms of the Human Cannabinoid Receptor CB1 Open
The G‐protein‐coupled human cannabinoid receptor 1 (CB1) is a promising therapeutic target for pain management, inflammation, obesity, and substance abuse disorders. The structures of CB1‐G i complexes in synthetic agonist‐bound forms have…
View article: Discovery of Natural Ah Receptor Antagonists from <i>Salvia miltiorrhiza</i> Bunge and Synthesis of Analogs for Tumor Immunotherapy
Discovery of Natural Ah Receptor Antagonists from <i>Salvia miltiorrhiza</i> Bunge and Synthesis of Analogs for Tumor Immunotherapy Open
IDO/TDO/Kyn/AhR signaling plays a crucial role in regulating innate and adaptive immunity, and targeting Ah receptor (AhR) inhibition can potentially redirect immune cells toward an antitumoral phenotype. Therefore, AhR is an attractive dr…