Quan Liu
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View article: Identification of embryonic yield-related serum biomarkers using proteomic analysis in ovine superovulation
Identification of embryonic yield-related serum biomarkers using proteomic analysis in ovine superovulation Open
Superovulation is an efficient technology for the propagation of excellent livestock. Blood proteins other than reproductive hormones might be related to the outcome of superovulation. In this study, to identify potential protein biomarker…
View article: Association of systemic immune-inflammatory index with all-cause and cardiovascular mortality among individuals with diabetes: Evidence from the NHANES 2001 to 2018
Association of systemic immune-inflammatory index with all-cause and cardiovascular mortality among individuals with diabetes: Evidence from the NHANES 2001 to 2018 Open
Evidence regarding the systemic immune-inflammatory index (SII) and mortality in patients with diabetes is limited. This study aimed to investigate the relationship of the SII with all-cause and cardiovascular mortality in patients with di…
View article: Identification and evolution of the plant sulfotransferase family
Identification and evolution of the plant sulfotransferase family Open
Sulfotransferases (SOTs, EC 2.8.2.-), which catalyze sulfate conjugation reactions, are widespread across prokaryotes and eukaryotes. However, the origin, classification and evolution history of SOTs in plants are not as well understood as…
View article: ST2 <sup>+</sup> Erythroid Progenitors Suppress Allergic Asthma by Scavenging IL‐33 in Young Mice
ST2 <sup>+</sup> Erythroid Progenitors Suppress Allergic Asthma by Scavenging IL‐33 in Young Mice Open
Background Although IL‐33/ST2 signaling has been implicated in adult asthma, its contribution to early‐onset allergic asthma remains poorly understood. Here, we examined the postnatal dynamics of IL‐33 and its regulation by splenic ST2 + e…
View article: Spatiotemporal Dynamics of Central Nervous System Diseases: Advancing Translational Neuropathology via Single‐Cell and Spatial Multiomics
Spatiotemporal Dynamics of Central Nervous System Diseases: Advancing Translational Neuropathology via Single‐Cell and Spatial Multiomics Open
Central nervous system (CNS) diseases, a leading cause of global disability and mortality, encompass a wide range of brain disorders such as stroke, Alzheimer's disease, Parkinson's disease, and so on. These diseases are characterized by d…
View article: Perioperative and mid-term prognosis in coronary artery bypass grafting patients with mild renal dysfunction
Perioperative and mid-term prognosis in coronary artery bypass grafting patients with mild renal dysfunction Open
For patients undergoing CABG, preoperative renal dysfunction is associated with an increased risk of postoperative AKI. However, no significant difference was observed in perioperative mortality and mid-term outcomes.
View article: Single-cell transcriptome sequencing reveals new epithelial-stromal associated mesenchymal-like subsets in recurrent gliomas
Single-cell transcriptome sequencing reveals new epithelial-stromal associated mesenchymal-like subsets in recurrent gliomas Open
View article: Chromosome Ordinal Number-Related Genomic Stability Revealed Among Oryza and Other Poaceae Plants
Chromosome Ordinal Number-Related Genomic Stability Revealed Among Oryza and Other Poaceae Plants Open
Rice (Oryza sativa) is one of the key staple crops, providing food for nearly half of the world’s population. The past twenty years have seen significant advances in understanding Oryza species through genome sequencing efforts. However, t…
View article: Exosomal circRNAs: key modulators in breast cancer progression
Exosomal circRNAs: key modulators in breast cancer progression Open
Breast cancer (BC) poses significant challenges globally, necessitating a deeper understanding of its complexities. Exosomes are cell-specific secreted extracellular vesicles of interest, characterized by a lipid bilayer structure. Exosome…
View article: Baohuoside I targets SaeR as an antivirulence strategy to disrupt MRSA biofilm formation and pathogenicity
Baohuoside I targets SaeR as an antivirulence strategy to disrupt MRSA biofilm formation and pathogenicity Open
View article: Progress in Early Nutritional Support in Acute Pancreatitis
Progress in Early Nutritional Support in Acute Pancreatitis Open
Acute pancreatitis (acute pancreatitis, AP) is an inflammatory reaction caused by cholelithiasis, alcohol, tumor and other factors of pancreatic enzymes, which causes digestion, edema, bleeding and even necrosis. Usually characterized by a…
View article: A study on the variation of cytokine and electrolyte levels in rhesus macaques, cynomolgus monkeys, and Assamese macaques
A study on the variation of cytokine and electrolyte levels in rhesus macaques, cynomolgus monkeys, and Assamese macaques Open
Background Non‐human primates (NPHs), such as rhesus macaques, cynomolgus monkeys, and Assamese macaques, play a crucial role in biomedical research. However, baseline cytokine and electrolyte data for these three species, particularly dat…
View article: The Dual Role of Macrophages in MIRI and MI by Immunity and Inflammation: Damage, Repair, Crosstalk, and Therapy
The Dual Role of Macrophages in MIRI and MI by Immunity and Inflammation: Damage, Repair, Crosstalk, and Therapy Open
The global prevalence of coronary artery disease (CAD) continues to escalate globally. A substantial proportion of CAD patients develop myocardial ischemic injury or myocardial infarction (MI), while reperfusion therapy paradoxically induc…
View article: Genome-wide identification, evolution and expression analysis of the <i>PP2C</i> gene family in ice plant
Genome-wide identification, evolution and expression analysis of the <i>PP2C</i> gene family in ice plant Open
View article: Risk factors for mortality in patients with sepsis on extracorporeal membrane oxygenation and/or continuous renal replacement therapy: a retrospective cohort study based on MIMIC-IV database
Risk factors for mortality in patients with sepsis on extracorporeal membrane oxygenation and/or continuous renal replacement therapy: a retrospective cohort study based on MIMIC-IV database Open
For septic patients requiring ECMO, prothrombin time was the key independent risk factor. For those needing CRRT, SOFA score was the most significant independent risk factor. Prior history of hypertension was the primary independent risk f…
View article: Molecular mechanisms and diagnostic model of glioma-related epilepsy
Molecular mechanisms and diagnostic model of glioma-related epilepsy Open
Epilepsy is one of the most common symptoms in patients with gliomas; however, the mechanisms underlying its interaction are not yet clear. Moreover, epidemiological studies have not accurately identified patients with glioma-related epile…
View article: Corrigendum: Alterations in cellular metabolism under different grades of glioma staging identified based on a multi-omics analysis strategy
Corrigendum: Alterations in cellular metabolism under different grades of glioma staging identified based on a multi-omics analysis strategy Open
[This corrects the article DOI: 10.3389/fendo.2023.1292944.].
View article: Calcium enrichment activity initiates extracellular calcium influx-dependent inflammatory response of biologically-derived hydroxyapatite
Calcium enrichment activity initiates extracellular calcium influx-dependent inflammatory response of biologically-derived hydroxyapatite Open
View article: Risk factors for mortality in patients receiving extracorporeal membrane oxygenation
Risk factors for mortality in patients receiving extracorporeal membrane oxygenation Open
CRRT implantation and age were independent risk factors for patients with ECMO implantation in a predominantly surgical cohort. In patients receiving a combination of CRRT and ECMO, lack of congenital heart disease and previous surgical hi…
View article: Association between triglyceride glucose-waist height ratio index and cardiovascular disease in middle-aged and older Chinese individuals: a nationwide cohort study
Association between triglyceride glucose-waist height ratio index and cardiovascular disease in middle-aged and older Chinese individuals: a nationwide cohort study Open
View article: Off-pump Versus On-pump Coronary Artery Bypass Grafting in Diabetic patients: A Meta-analysis of Observational Studies with a Propensity-Score Analysis
Off-pump Versus On-pump Coronary Artery Bypass Grafting in Diabetic patients: A Meta-analysis of Observational Studies with a Propensity-Score Analysis Open
Purpose The debate between off-pump coronary artery bypass grafting (OPCAB) and on-pump coronary artery bypass grafting (ONCAB) in diabetic patients remains. This meta-analysis aimed to investigate outcomes after OPCAB versus ONCAB for pat…
View article: sVEGFR-3 alleviates myocardial ischemia/reperfusion injury through regulating mitochondrial homeostasis and immune cell infiltration
sVEGFR-3 alleviates myocardial ischemia/reperfusion injury through regulating mitochondrial homeostasis and immune cell infiltration Open
Recent studies have suggested that sVEGFR-3 is involved with cardiac disease by regulating lymphangiogenesis; however, results are inconsistent. The purpose of this study was to investigate the role and mechanism of sVEGFR-3 in myocardial …
View article: A 3‐month‐old neonatal rhesus macaque HFMD model caused by coxsackievirus B1 infection and viral tissue tropism
A 3‐month‐old neonatal rhesus macaque HFMD model caused by coxsackievirus B1 infection and viral tissue tropism Open
Coxsackievirus B1 (CVB1), an enterovirus with multiple clinical presentations, has been associated with potential long‐term consequences, including hand, foot, and mouth disease (HFMD), in some patients. However, the related animal models,…
View article: Hydroxycitric Acid Tripotassium Hydrate Attenuates Monocrotaline and Hypoxia-Induced Pulmonary Hypertension in Rats
Hydroxycitric Acid Tripotassium Hydrate Attenuates Monocrotaline and Hypoxia-Induced Pulmonary Hypertension in Rats Open
This study shows that hydroxycitric acid tripotassium hydrate can alleviate pulmonary hypertension caused by hypoxia and monocycloline in rats, improve remodeling of the right ventricle and pulmonary artery, and inhibit pulmonary artery sm…
View article: Phosphoglycerate Kinase 1: An Effective Therapeutic Target in Cancer
Phosphoglycerate Kinase 1: An Effective Therapeutic Target in Cancer Open
Phosphoglycerate kinase 1 (PGK1) serves as a pivotal enzyme in the cellular glycolysis pathway, facilitating adenosine-triphosphate (ATP) production in tumor cells and driving the Warburg effect. PGK1 generates ATP through the reversible p…
View article: Coxsackievirus B3 HFMD animal models in Syrian hamster and rhesus monkey
Coxsackievirus B3 HFMD animal models in Syrian hamster and rhesus monkey Open
Coxsackievirus B3 (CVB3) is the pathogen causing hand, foot and mouth disease (HFMD), which manifests across a spectrum of clinical severity from mild to severe. However, CVB3-infected mouse models mainly demonstrate viral myocarditis and …
View article: Single-cell analysis reveals alterations in cellular composition and cell-cell communication associated with airway inflammation and remodeling in asthma
Single-cell analysis reveals alterations in cellular composition and cell-cell communication associated with airway inflammation and remodeling in asthma Open
Background Asthma is a heterogeneous disease characterized by airway inflammation and remodeling, whose pathogenetic complexity was associated with abnormal responses of various cell types in the lung. The specific interactions between imm…
View article: Novel Ring for Tricuspid Annuloplasty: A Feasibility Study in Animal Model
Novel Ring for Tricuspid Annuloplasty: A Feasibility Study in Animal Model Open
Background Tricuspid regurgitation (TR) is the most common disease of the tricuspid valve, and tricuspid valvuloplasty is the main treatment method. Currently, most tricuspid annuloplasty rings are incomplete and rigid and can easily cause…
View article: Glycogen metabolism-mediated intercellular communication in the tumor microenvironment influences liver cancer prognosis
Glycogen metabolism-mediated intercellular communication in the tumor microenvironment influences liver cancer prognosis Open
Glycogen metabolism plays a key role in the development of hepatocellular carcinoma (HCC), but the function of glycogen metabolism genes in the tumor microenvironment (TME) is still to be elucidated. Single-cell RNA-seq data were obtained …
View article: Alterations in cellular metabolism under different grades of glioma staging identified based on a multi-omics analysis strategy
Alterations in cellular metabolism under different grades of glioma staging identified based on a multi-omics analysis strategy Open
Glioma is a type of brain tumor closely related to abnormal cell metabolism. Firstly, multiple combinatorial sequencing studies have revealed this relationship. Genomic studies have identified gene mutations and gene expression disorders r…