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View article: Clinical features and recurrence risk prediction model in patients with idiopathic inflammatory myopathies-associated interstitial lung disease: a retrospective study from Ningbo
Clinical features and recurrence risk prediction model in patients with idiopathic inflammatory myopathies-associated interstitial lung disease: a retrospective study from Ningbo Open
Background Idiopathic inflammatory myopathies (IIMs) are characterized by chronic muscle inflammation and often involve multiple organ systems. Despite treatment, a large number of patients still experience relapse or disease progression. …
View article: [Perioperative management of a patient with hemophilia a and high-titer inhibitors and literature review].
[Perioperative management of a patient with hemophilia a and high-titer inhibitors and literature review]. Open
A 64-year-old male patient with hemophilia A was scheduled for the surgical removal of a pulmonary mass. Preoperative evaluation revealed that the coagulation factor Ⅷ (FⅧ) activity was 0.5%, with an F Ⅷ inhibitor level of 32 BU/ml; the R …
View article: The Role and Clinical Significance of Vitamin D in Chronic Obstructive Pulmonary Disease
The Role and Clinical Significance of Vitamin D in Chronic Obstructive Pulmonary Disease Open
Vitamin D is well known for its role in bones, but it also has a variety of extra-skeletal effects. Vitamin D deficiency is becoming a global health problem. Chronic obstructive pulmonary disease (COPD) is the third leading cause of death …
View article: Interleukin −39 Expression in Pleural Effusion and Its Diagnostic Value for Tuberculous Pleurisy
Interleukin −39 Expression in Pleural Effusion and Its Diagnostic Value for Tuberculous Pleurisy Open
IL-39 demonstrated good diagnostic and differential diagnostic value for TPE. Furthermore, the multivariate diagnostic model, as well as the joint detection of IL-39 with other tuberculosis biomarkers, can further increased the sensitivity…
View article: Clinical characteristics and prognosis of amyopathic dermatomyositis patients with interstitial lung disease: insights from a retrospective cohort
Clinical characteristics and prognosis of amyopathic dermatomyositis patients with interstitial lung disease: insights from a retrospective cohort Open
Introduction The diagnosis of amyopathic dermatomyositis with interstitial lung disease (ADM-ILD) is challenging due to the lack of typical skin features and overlapping syndromes. We aimed to determine the characteristics and prognosis of…
View article: Outcomes and predictors of progression in progressive pulmonary fibrosis
Outcomes and predictors of progression in progressive pulmonary fibrosis Open
Patients who were older, had high CA-153 and LDH levels, had poor pulmonary function test results, or had a UIP-like pattern on chest HRCT were more likely to have indications for the progression of f-ILD to PPF. Increased SPAP and AE are …
View article: Increased serum IL‑41 associated with acute exacerbation of chronic obstructive pulmonary disease
Increased serum IL‑41 associated with acute exacerbation of chronic obstructive pulmonary disease Open
Interleukin (IL)-41 is a novel immunomodulatory cytokine involved in the pathogenesis of several inflammatory and metabolic illnesses. However, it remains unclear how IL-41 contributes to the pathogenesis of chronic obstructive pulmonary d…
View article: Clinical significance of microscopic polyangiitis with interstitial lung disease and bronchiectasis: probability of preexisting comorbidities
Clinical significance of microscopic polyangiitis with interstitial lung disease and bronchiectasis: probability of preexisting comorbidities Open
Patients with MPA have a high prevalence of pulmonary involvement, and ILD is the most common subtype of MPA. ILD and BE can be considered preexisting comorbidities of MPA. Elevated serum creatinine was associated with shorter survival. Ho…
View article: Using the serum LDH level as a biomarker for amyopathic dermatomyositis with interstitial lung disease: A retrospective study of 158 patients with nonspecific interstitial pneumonia or organizing pneumonia
Using the serum LDH level as a biomarker for amyopathic dermatomyositis with interstitial lung disease: A retrospective study of 158 patients with nonspecific interstitial pneumonia or organizing pneumonia Open
Background Lactate dehydrogenase (LDH) is an easily obtained biological marker and a promising index for determining the severity of amyopathic dermatomyositis with interstitial lung disease (ADM-ILD). In this study, we retrospectively ana…
View article: Clinical significance of microscopic polyangiitis with interstitial lung disease and bronchiectasis: probability of preexisting comorbidities
Clinical significance of microscopic polyangiitis with interstitial lung disease and bronchiectasis: probability of preexisting comorbidities Open
The association between pulmonary involvement and microscopic polyangiitis (MPA) has been increasingly recognized in recent years. Whether interstitial lung disease (ILD) and bronchiectasis (BE) are disease manifestations of MPA, preexisti…
View article: A novel biomarker for pleural effusion diagnosis: Interleukin‐36γ in pleural fluid
A novel biomarker for pleural effusion diagnosis: Interleukin‐36γ in pleural fluid Open
Background Numerous studies have described the critical importance of interleukin (IL) ‐36γ in host defense against lung infections, but it is unknown whether it plays a role in infectious pleural effusion (IPE). This study aimed to examin…
View article: Clinical significance of acute exacerbation in interstitial lung disease with antineutrophil cytoplasmic antibody: an indicator of poor prognosis
Clinical significance of acute exacerbation in interstitial lung disease with antineutrophil cytoplasmic antibody: an indicator of poor prognosis Open
Background: The association between interstitial lung disease (ILD) and antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) has been increasingly recognized in recent years. The clinical features and prognostic differenc…
View article: <p>Serum IL-8 and VEGFA are Two Promising Diagnostic Biomarkers of Asthma-COPD Overlap Syndrome</p>
Serum IL-8 and VEGFA are Two Promising Diagnostic Biomarkers of Asthma-COPD Overlap Syndrome Open
The results suggested that IL-8 was highly sensitive and VEGFA was highly specificity, both of which could be used as biomarkers for the diagnosis of ACOS.
View article: Dieulafoy disease of the bronchus involving bilateral arteries
Dieulafoy disease of the bronchus involving bilateral arteries Open
Rationale: Dieulafoy disease of the bronchus is a rare vascular deformity. To the best of our knowledge, reports of these involving both lung vascular are hitherto absent. Patient concerns: A 67-year-old male was admitted to our department…
View article: Exhaled nitric oxide in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
Exhaled nitric oxide in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis Open
Our studies demonstrated a mild elevation of FENO in COPD, and the association between exacerbated COPD and FENO levels needs to be further explored. The potential mechanism is still unknown and conflicting.
View article: Olanzapine-induced peripheral eosinophilia and eosinophilic pleural effusion
Olanzapine-induced peripheral eosinophilia and eosinophilic pleural effusion Open
This case is a reminder that olanzapine may be a potential agent for EPE, and that this should be considered in clinical practice.
View article: Correction to: Dabigatran-Induced Massive Spontaneous Hemothorax
Correction to: Dabigatran-Induced Massive Spontaneous Hemothorax Open
Page 3, Table 2, 'Renal function indexes at different dates after admission': The cell entry in column 2, detailing the patient's urea concentration (μmol/L) on Day 1.
View article: Dabigatran-Induced Massive Spontaneous Hemothorax
Dabigatran-Induced Massive Spontaneous Hemothorax Open
Spontaneous hemothorax due to anticoagulant use is extremely rare in clinical practice. Dabigatran is a novel anticoagulant to prevent stroke or thromboembolic episodes in patients with nonvalvular atrial fibrillation. We report on an 83-y…