Robin L. Bailey
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View article: Schistosomiasis amongst adolescent boys in non-lakeshore southern Malawi: Investigating local risk-factors within a nested community-based cross-sectional survey
Schistosomiasis amongst adolescent boys in non-lakeshore southern Malawi: Investigating local risk-factors within a nested community-based cross-sectional survey Open
Background Schistosomiasis is endemic to Malawi, where preventive chemotherapy by mass drug administration (MDA) has been the foundational public health strategy for over a decade. Despite ongoing control, our understanding of the contempo…
View article: Embedding rewilding in policy: Perspectives on overcoming barriers and unlocking opportunities
Embedding rewilding in policy: Perspectives on overcoming barriers and unlocking opportunities Open
Rewilding initiatives are increasing in number across Europe and the UK in response to a growing awareness of substantial nature depletion, despite a lack of policy, guidance and legislation. Ongoing transformations of UK environmental pol…
View article: Tropical Data: Approach and Methodology as Applied to Trachoma Prevalence Surveys.
Tropical Data: Approach and Methodology as Applied to Trachoma Prevalence Surveys. Open
Population-based prevalence surveys are essential for decision-making on interventions to achieve trachoma elimination as a public health problem. This paper outlines the methodologies of Tropical Data, which supports work to undertake tho…
View article: Design considerations for incorporating serological monitoring into trachoma prevalence surveys
Design considerations for incorporating serological monitoring into trachoma prevalence surveys Open
Serology is increasingly used to monitor disease transmission and elimination. Embedding dried blood spot collection in trachoma surveys allows transmission intensity inference through population-level seroconversion rates (SCR) estimation…
View article: Biannual Mass Azithromycin Distributions for Preschool Children and Malaria Parasitemia
Biannual Mass Azithromycin Distributions for Preschool Children and Malaria Parasitemia Open
Importance Mass azithromycin distributions may reduce malaria parasitemia in the short term, but longer-term effectiveness is unclear. Objective To examine whether biannual mass azithromycin distributions are associated with lower rates of…
View article: Chlamydia and gonorrhoea infections in young Kenyan HIV-negative cisgender men who have sex with men and transgender women: a multicentre cohort study
Chlamydia and gonorrhoea infections in young Kenyan HIV-negative cisgender men who have sex with men and transgender women: a multicentre cohort study Open
Objectives To assess the prevalence, incidence and factors associated with Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection among HIV-negative men who have sex with men (MSM) and transgender women (TGW) in Kenya. Design …
View article: Evolutionary dynamics in the genome of ocular Chlamydia trachomatis strains from Northern Tanzania following mass drug administration
Evolutionary dynamics in the genome of ocular Chlamydia trachomatis strains from Northern Tanzania following mass drug administration Open
Trachoma, caused by Chlamydia trachomatis (Ct), remains a leading cause of preventable infection-induced blindness worldwide. We conducted a 4-year longitudinal study in three trachoma-endemic villages in Northern Tanzania, tracking infect…
View article: Characterizing trachoma elimination using serology
Characterizing trachoma elimination using serology Open
Trachoma is targeted for global elimination as a public health problem by 2030. Measurement of IgG antibodies in children is being considered for surveillance and programmatic decision-making. There are currently no programmatic guidelines…
View article: Long-term effects of azithromycin mass administration to reduce childhood mortality on Streptococcus pneumoniae antimicrobial resistance: a population-based, cross-sectional, follow-up carriage survey
Long-term effects of azithromycin mass administration to reduce childhood mortality on Streptococcus pneumoniae antimicrobial resistance: a population-based, cross-sectional, follow-up carriage survey Open
The Gates Foundation, the National Institute for Health and Care Research, and the Wellcome Trust.
View article: Core Outcome Set development for LEPtospirosis trials (COS-LEP): a study protocol to develop a core outcome set for the evaluation of clinical therapeutic interventions for human leptospirosis
Core Outcome Set development for LEPtospirosis trials (COS-LEP): a study protocol to develop a core outcome set for the evaluation of clinical therapeutic interventions for human leptospirosis Open
Background Leptospirosis is a zoonotic bacterial infection occurring worldwide. It is of particular public health concern due to its global distribution, epidemic potential and high mortality without appropriate treatment. The method for t…
View article: Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets
Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets Open
Soil-transmitted helminths (STHs) are intestinal pathogens affecting over a billion people worldwide. STH control relies on microsopy-based diagnostics to monitor parasite prevalence and enable post-treatment surveillance, however, molecul…
View article: Characterizing trachoma elimination using serology
Characterizing trachoma elimination using serology Open
Trachoma is targeted for global elimination as a public health problem by 2030. Measurement of IgG antibodies in children is being considered for surveillance and programmatic decision-making. There are currently no guidelines for applicat…
View article: Core Outcome Set development for LEPtospirosis trials (COS-LEP): a study protocol to develop a core outcome set for the evaluation of clinical therapeutic interventions for human Leptospirosis
Core Outcome Set development for LEPtospirosis trials (COS-LEP): a study protocol to develop a core outcome set for the evaluation of clinical therapeutic interventions for human Leptospirosis Open
Background Leptospirosis is a zoonotic bacterial infection occurring worldwide. It is of particular public health concern due to its global distribution, epidemic potential and high mortality without appropriate treatment. The method for t…
View article: Disability in childhood and the equity of health services: a cross-sectional comparison of mass drug administration strategies for soil-transmitted helminths in southern Malawi
Disability in childhood and the equity of health services: a cross-sectional comparison of mass drug administration strategies for soil-transmitted helminths in southern Malawi Open
Background School-based approaches are an efficient mechanism for the delivery of basic health services, but may result in the exclusion of children with disabilities if they are less likely to participate in schooling. Community-based ‘do…
View article: Evolutionary Dynamics in the Genome of Ocular Chlamydia trachomatis Strains from Northern Tanzania, pre- and post- Mass Drug Administration
Evolutionary Dynamics in the Genome of Ocular Chlamydia trachomatis Strains from Northern Tanzania, pre- and post- Mass Drug Administration Open
Trachoma, caused by Chlamydia trachomatis (Ct), remains a leading cause of preventable infection induced blindness worldwide. We conducted a four-year longitudinal study in three trachoma-endemic villages in Northern Tanzania, tracking inf…
View article: Evolutionary Dynamics in the Genome of Ocular Chlamydia trachomatis Strains from Northern Tanzania, pre- and post- Mass Drug Administration
Evolutionary Dynamics in the Genome of Ocular Chlamydia trachomatis Strains from Northern Tanzania, pre- and post- Mass Drug Administration Open
Trachoma, caused by Chlamydia trachomatis (Ct), remains a leading cause of preventable infection induced blindness worldwide. We conducted a four-year longitudinal study in three trachoma-endemic villages in Northern Tanzania, tracking inf…
View article: Genomic insights into local-scale evolution of ocular Chlamydia trachomatis strains within and between individuals in Gambian trachoma-endemic villages
Genomic insights into local-scale evolution of ocular Chlamydia trachomatis strains within and between individuals in Gambian trachoma-endemic villages Open
Trachoma, a neglected tropical disease caused by Chlamydia trachomatis (Ct) serovars A–C, is the leading infectious cause of blindness worldwide. Africa bears the highest burden, accounting for over 86 % of global trachoma cases. We invest…
View article: Genomic insights into local scale evolution of ocular<i>Chlamydia trachomatis</i>strains within and between individuals in Gambian trachoma-endemic villages
Genomic insights into local scale evolution of ocular<i>Chlamydia trachomatis</i>strains within and between individuals in Gambian trachoma-endemic villages Open
Trachoma, a neglected tropical disease caused by Chlamydia trachomatis (Ct) serovar A-C, is the leading infectious cause of blindness worldwide. Its impact is substantial, with approximately 1.9 million individuals suffering from visual im…
View article: Tropical Data: Approach and Methodology as Applied to Trachoma Prevalence Surveys
Tropical Data: Approach and Methodology as Applied to Trachoma Prevalence Surveys Open
This health ministry-led, standardised approach, with support from the start to the end of the survey process, has helped all trachoma elimination stakeholders to know where interventions are needed, where interventions can be stopped, and…
View article: Longitudinal changes in tear cytokines and antimicrobial proteins in trachomatous disease
Longitudinal changes in tear cytokines and antimicrobial proteins in trachomatous disease Open
Background Trachoma is a neglected tropical disease caused by ocular infection with Chlamydia trachomatis , where repeated infections and chronic inflammation can ultimately result in scarring, trichiasis and blindness. While scarring is t…
View article: Synonymous Myocilin mutations break their silence in a Zambian population attending selected referral eye health facilities
Synonymous Myocilin mutations break their silence in a Zambian population attending selected referral eye health facilities Open
Objective: Primary open-angle glaucoma in Zambia has an earlier age of onset and appears to be more clinically severe. Myocilin mutations are associated with primary open angle glaucoma in multiple populations. Therefore, we investigated t…
View article: Risk factors for postsurgical trichiasis recurrence in a trachoma-endemic area
Risk factors for postsurgical trichiasis recurrence in a trachoma-endemic area Open
PURPOSE. The World Health Organization recommends trichiasis surgery to prevent blindness caused by trachoma; however, recurrence is common. Risk factors for recurrence have not been widely studied, particularly in trachoma hyperendemic ar…
View article: Chlamydial positivity of nasal discharge at baseline is associated with ocular chlamydial positivity 2 months following azithromycin treatment
Chlamydial positivity of nasal discharge at baseline is associated with ocular chlamydial positivity 2 months following azithromycin treatment Open
BACKGROUND. Trachoma is the leading infectious cause of blindness. Routes of transmission remain unclear. In this study, the relationship between Chlamydia trachomatis Amplicor-positive nasal discharge and Amplicor-positive ocular swabs wa…