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View article: The Influence of Diabetes Mellitus and Kidney Dysfunction on Oxidative Stress, a Reflection of the Multisystem Interactions in Aortic Stenosis
The Influence of Diabetes Mellitus and Kidney Dysfunction on Oxidative Stress, a Reflection of the Multisystem Interactions in Aortic Stenosis Open
Progression of aortic stenosis (AS) is aggravated by type 2 Diabetes Mellitus (T2DM) and kidney dysfunction (KD). Oxidative stress is one of the main mechanisms that triggers AS and is also disturbed among subjects with T2DM and KD. Conseq…
View article: Impact of the Addition of Daratumumab to the Frontline Treatment of Patients with Immunoglobulin Light-Chain Amyloidosis: A Single-Centre Experience
Impact of the Addition of Daratumumab to the Frontline Treatment of Patients with Immunoglobulin Light-Chain Amyloidosis: A Single-Centre Experience Open
Background: Daratumumab-based regimens represent the gold-standard therapy for newly diagnosed AL amyloidosis patients. However, there are few studies about the efficacy of this treatment in real life. Methods: This study included 99 patie…
View article: Author response: Novel risk loci for COVID-19 hospitalization among admixed American populations
Author response: Novel risk loci for COVID-19 hospitalization among admixed American populations Open
View article: Novel risk loci for COVID-19 hospitalization among admixed American populations
Novel risk loci for COVID-19 hospitalization among admixed American populations Open
The genetic basis of severe COVID-19 has been thoroughly studied, and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of populatio…
View article: Novel risk loci for COVID-19 hospitalization among admixed American populations
Novel risk loci for COVID-19 hospitalization among admixed American populations Open
The genetic basis of severe COVID-19 has been thoroughly studied, and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of populatio…
View article: Author response: Novel risk loci for COVID-19 hospitalization among admixed American populations
Author response: Novel risk loci for COVID-19 hospitalization among admixed American populations Open
View article: Reviewer #2 (Public Review): Novel risk loci for COVID-19 hospitalization among admixed American populations
Reviewer #2 (Public Review): Novel risk loci for COVID-19 hospitalization among admixed American populations Open
The genetic basis of severe COVID-19 has been thoroughly studied and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of population…
View article: Novel risk loci for COVID-19 hospitalization among admixed American populations
Novel risk loci for COVID-19 hospitalization among admixed American populations Open
The genetic basis of severe COVID-19 has been thoroughly studied and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of population…
View article: Reviewer #1 (Public Review): Novel risk loci for COVID-19 hospitalization among admixed American populations
Reviewer #1 (Public Review): Novel risk loci for COVID-19 hospitalization among admixed American populations Open
The genetic basis of severe COVID-19 has been thoroughly studied and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of population…
View article: Reviewer #3 (Public Review): Novel risk loci for COVID-19 hospitalization among admixed American populations
Reviewer #3 (Public Review): Novel risk loci for COVID-19 hospitalization among admixed American populations Open
The genetic basis of severe COVID-19 has been thoroughly studied and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of population…
View article: Novel risk loci for COVID-19 hospitalization among admixed American populations
Novel risk loci for COVID-19 hospitalization among admixed American populations Open
The genetic basis of severe COVID-19 has been thoroughly studied, and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of populatio…
View article: Cardiotoxicity Secondary to Immune Checkpoint Inhibitors in the Elderly: Safety in Real-World Data
Cardiotoxicity Secondary to Immune Checkpoint Inhibitors in the Elderly: Safety in Real-World Data Open
Introduction: Immunotherapy represents a key pillar of cancer treatments, with high response rates and long survival. Its use is increasing, mainly at the expense of the geriatric population due to the ageing of this population. However, d…
View article: Novel risk loci for COVID-19 hospitalization among admixed American populations
Novel risk loci for COVID-19 hospitalization among admixed American populations Open
The genetic basis of severe COVID-19 has been thoroughly studied, and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of populatio…
View article: PB2102: IMPACT OF AUTOLOGOUS STEM CELL TRASPLANTATION IN AL AMYLOIDOSIS. EXPERIENCE IN A SINGLE TERTIARY HOSPITAL
PB2102: IMPACT OF AUTOLOGOUS STEM CELL TRASPLANTATION IN AL AMYLOIDOSIS. EXPERIENCE IN A SINGLE TERTIARY HOSPITAL Open
Topic: 14. Myeloma and other monoclonal gammopathies - Clinical Background: AL amyloidosis is a clonal plasma cell (PC) disorder characterized by deposition of amyloid fibrils leading to organ disfunction. Treatment must be risk-adapted. T…
View article: The heart and SARS-CoV-2
The heart and SARS-CoV-2 Open
View article: Case Report: Renal relapse after heart transplantation, induction, and autologous stem cell transplantation in a patient with AL amyloidosis with exclusive cardiac involvement
Case Report: Renal relapse after heart transplantation, induction, and autologous stem cell transplantation in a patient with AL amyloidosis with exclusive cardiac involvement Open
There is no recommendation on what salvage therapy is optimal in the solid organ recipient with AL amyloidosis, such as a heart transplant. With this case, we illustrate how treatment with daratumumab may be effective and safe in a patient…
View article: Corazón y SARS-CoV-2
Corazón y SARS-CoV-2 Open
View article: Novel genes and sex differences in COVID-19 severity
Novel genes and sex differences in COVID-19 severity Open
Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE consortium). In …
View article: Mean Velocity of the Pulmonary Artery as a Clinically Relevant Prognostic Indicator in Patients with Heart Failure with Preserved Ejection Fraction
Mean Velocity of the Pulmonary Artery as a Clinically Relevant Prognostic Indicator in Patients with Heart Failure with Preserved Ejection Fraction Open
Background: Right ventricular (RV) to pulmonary circulation (PC) coupling can stratify prognosis in heart failure (HF). In this study, we assessed the prognostic role of the mean velocity of the pulmonary artery (mvPA) determined by cardia…
View article: Afección pericárdica y miocárdica tras infección por SARS-CoV-2: estudio descriptivo transversal en trabajadores sanitarios
Afección pericárdica y miocárdica tras infección por SARS-CoV-2: estudio descriptivo transversal en trabajadores sanitarios Open
View article: Pericardial and myocardial involvement after SARS-CoV-2 infection: a cross-sectional descriptive study in healthcare workers
Pericardial and myocardial involvement after SARS-CoV-2 infection: a cross-sectional descriptive study in healthcare workers Open
View article: Pericarditis and myocarditis long after SARS-CoV-2 infection: a cross-sectional descriptive study in health-care workers
Pericarditis and myocarditis long after SARS-CoV-2 infection: a cross-sectional descriptive study in health-care workers Open
Background Cardiac sequelae of past SARS-CoV-2 infection are still poorly documented. We conducted a cross-sectional study in health-care workers to report evidence of pericarditis and myocarditis after SARS-CoV-2 infection. Methods We stu…
View article: C-Reactive protein and SOFA score as early predictors of critical care requirement in patients with COVID-19 pneumonia in Spain
C-Reactive protein and SOFA score as early predictors of critical care requirement in patients with COVID-19 pneumonia in Spain Open
Background Some patients infected by SARS-CoV-2 in the recent pandemic have required critical care, becoming one of the main limitations of the health systems. Our objective has been to identify potential markers at admission predicting th…
View article: Does Chronic Kidney Disease Facilitate Malignant Myocardial Fibrosis in Heart Failure with Preserved Ejection Fraction of Hypertensive Origin?
Does Chronic Kidney Disease Facilitate Malignant Myocardial Fibrosis in Heart Failure with Preserved Ejection Fraction of Hypertensive Origin? Open
In hypertensive patients with heart failure (HF) a serum biomarker combination of high carboxy-terminal propeptide of procollagen type-I (PICP) and low carboxy-terminal telopeptide of collagen type-I to matrix metalloproteinase-1 (CITP:MMP…
View article: P649 Before and after: sinus venosus atrial septal defect
P649 Before and after: sinus venosus atrial septal defect Open
Introduction The diagnosis of sinus venosus atrial septal defect (SVASD) is complex and requires special imaging. Surgery is the conventional treatment; however, transcatheter repair may become an attractive option. Case report A 60 year-o…
View article: P130The role of cardiac magnetic resonance in malignant cardiac tumours, a weapon of mass utility
P130The role of cardiac magnetic resonance in malignant cardiac tumours, a weapon of mass utility Open
Clinical background: A 74-year-old male without previous heart disease presented to the emergency room referring one month of dyspnoea and weight loss.His chest X-ray revealed cardiomegaly and mild bilateral pleural effusion.The echocardio…
View article: P127Cardiac involvement in Erdheim-Chester disorder, a rare case of right atrial pseudo-tumour.
P127Cardiac involvement in Erdheim-Chester disorder, a rare case of right atrial pseudo-tumour. Open
Clinical background: A 69-year-old male was referred to our hospital in 2015 with a long history of hypertension, chronic kidney disease and systemic inflammation.During follow-up, the patient developed several systemic manifestations that…
View article: P6490Myocardial T2 in aortic stenosis: compensatory vasodilatation or subacute inflammation?
P6490Myocardial T2 in aortic stenosis: compensatory vasodilatation or subacute inflammation? Open
View article: P3431A comparison of phenotypes of left-dominant arrhythmogenic cardiomyopathy and dilated cardiomyopathy
P3431A comparison of phenotypes of left-dominant arrhythmogenic cardiomyopathy and dilated cardiomyopathy Open