Ramon Diaz‐Arrastia
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View article: Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults
Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults Open
Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals wi…
View article: From acute injury to chronic comorbidity: Interrupted time series modeling of traumatic brain injury impact among post-9/11 veterans
From acute injury to chronic comorbidity: Interrupted time series modeling of traumatic brain injury impact among post-9/11 veterans Open
Traumatic brain injury (TBI) is associated with a variety of adverse health outcomes that display complex behavior over time. The objective of this study was to investigate both the early and late health impacts of TBI within a single fram…
View article: Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators
Beyond mild, moderate, and severe traumatic brain injury: modelling severity from clinical, neuroimaging, and blood-based indicators Open
View article: Factors Associated With Persistent Symptoms Following Mild Traumatic Brain Injury
Factors Associated With Persistent Symptoms Following Mild Traumatic Brain Injury Open
IMPORTANCE Traumatic brain injury (TBI) is a common presentation in which it is clinically difficult at presentation to identify patients at risk for persistent symptoms, defined as lasting longer than 30 days. Few studies report the time …
View article: Acute Surgery vs Conservative Treatment for Traumatic Acute Subdural Hematoma
Acute Surgery vs Conservative Treatment for Traumatic Acute Subdural Hematoma Open
Importance It is unclear whether performing surgery for most patients with an acute subdural hematoma (ASDH) and traumatic brain injury (TBI) is superior to conservative treatment. Objective To compare the effectiveness of a strategy prefe…
View article: Traumatic brain injury, changes in plasma amyloid, tau, and neurodegenerative biomarkers, and dementia risk
Traumatic brain injury, changes in plasma amyloid, tau, and neurodegenerative biomarkers, and dementia risk Open
INTRODUCTION Long‐term trajectories of plasma biomarkers in relation to incident traumatic brain injury (TBI) and whether TBI modifies associations of biomarkers with dementia risk are unknown. METHODS One thousand fifty Atherosclerosis Ri…
View article: Vascular Risk Factors and 1-Year Cognitive Change Among Individuals With Traumatic Brain Injury
Vascular Risk Factors and 1-Year Cognitive Change Among Individuals With Traumatic Brain Injury Open
Importance Traumatic brain injury (TBI) and vascular risk factors are associated with cognitive impairment, but it is unknown if individuals with vascular risk factors experience worse cognitive outcomes after TBI. Objective To evaluate co…
View article: Association of Traumatic Meningeal Enhancement on MRI With Clinical Recovery in Patients With Traumatic Brain Injury
Association of Traumatic Meningeal Enhancement on MRI With Clinical Recovery in Patients With Traumatic Brain Injury Open
View article: From acute injury to chronic comorbidity: Interrupted time series modeling of traumatic brain injury impact among post-9/11 veterans
From acute injury to chronic comorbidity: Interrupted time series modeling of traumatic brain injury impact among post-9/11 veterans Open
Traumatic brain injury (TBI) is associated with a variety of adverse health outcomes that display complex behavior over time. The objective of this study was to investigate both the early and late health impacts of TBI within a single fram…
View article: MicroRNAs Detected in Whole Blood Following Traumatic Brain Injury Are Associated with Recovery 6 Months after Injury
MicroRNAs Detected in Whole Blood Following Traumatic Brain Injury Are Associated with Recovery 6 Months after Injury Open
Traumatic brain injury (TBI) is a heterogeneous disease from which incomplete recovery is unfortunately common. Biomarkers prognostic of future recovery are currently lacking. MicroRNAs (miRNAs), small noncoding RNAs, are attractive potent…
View article: Mediators of epilepsy risk after traumatic brain injury: A 20‐year <scp>U.S.</scp> veteran cohort study
Mediators of epilepsy risk after traumatic brain injury: A 20‐year <span>U.S.</span> veteran cohort study Open
Objective Traumatic brain injury (TBI) is a significant risk factor for epilepsy, but little work has explored whether risk of epilepsy after TBI may operate through intermediary mechanisms. The objective of this study was to statistically…
View article: Clinical profile of patients with acute traumatic brain injury undergoing cranial surgery in the United States: report from the 18-centre TRACK-TBI cohort study
Clinical profile of patients with acute traumatic brain injury undergoing cranial surgery in the United States: report from the 18-centre TRACK-TBI cohort study Open
View article: Biomarkers of long-term consequences of traumatic brain injuries sustained during military service
Biomarkers of long-term consequences of traumatic brain injuries sustained during military service Open
View article: Performance of Diagnostic Biomarkers for Traumatic Brain Injury Within the First Hour—Expanding Their Clinical Utility
Performance of Diagnostic Biomarkers for Traumatic Brain Injury Within the First Hour—Expanding Their Clinical Utility Open
View article: Automated Measurement of Cerebral Hemorrhagic Contusions and Outcomes After Traumatic Brain Injury in the TRACK-TBI Study
Automated Measurement of Cerebral Hemorrhagic Contusions and Outcomes After Traumatic Brain Injury in the TRACK-TBI Study Open
Importance Because withdrawal of life-sustaining therapy based on perceived poor prognosis is the most common cause of death after moderate or severe traumatic brain injury (TBI), the accuracy of clinical prognoses is directly associated w…
View article: Return of intracranial beta oscillations and traveling waves with recovery from traumatic brain injury
Return of intracranial beta oscillations and traveling waves with recovery from traumatic brain injury Open
Traumatic brain injury (TBI) remains a pervasive clinical problem associated with significant morbidity and mortality. However, TBI remains clinically and biophysically ill-defined, and prognosis remains difficult even with the standardiza…
View article: Traumatic brain injury and cognitive change over 30 years among community‐dwelling older adults
Traumatic brain injury and cognitive change over 30 years among community‐dwelling older adults Open
INTRODUCTION There is limited evidence regarding the rate of long‐term cognitive decline after traumatic brain injury (TBI) among older adults. METHODS In this prospective cohort study, time‐varying TBI was defined by self‐report and Inter…
View article: Serum NfL and GFAP as biomarkers of progressive neurodegeneration in TBI
Serum NfL and GFAP as biomarkers of progressive neurodegeneration in TBI Open
BACKGROUND We examined spatial patterns of brain atrophy after mild, moderate, and severe traumatic brain injury (TBI), the relationship between progression of brain atrophy with initial traumatic axonal injury (TAI), cognitive outcome, an…
View article: Head Injury and Risk of Incident Ischemic Stroke in Community-Dwelling Adults
Head Injury and Risk of Incident Ischemic Stroke in Community-Dwelling Adults Open
BACKGROUND: While stroke is a recognized short-term sequela of traumatic brain injury, evidence about long-term ischemic stroke risk after traumatic brain injury remains limited. METHODS: The Atherosclerosis Risk in Communities Study is an…
View article: Change in Enlarged Perivascular Spaces over Time and Associations with Outcomes After Traumatic Brain Injury
Change in Enlarged Perivascular Spaces over Time and Associations with Outcomes After Traumatic Brain Injury Open
Enlarged perivascular spaces (EPVs) can be seen on magnetic resonance imaging (MRI) scans in various neurological diseases, including traumatic brain injury (TBI). EPVs have been associated with cognitive dysfunction and sleep disturbances…
View article: Effects of Low-Level Light Therapy on Resting-State Connectivity Following Moderate Traumatic Brain Injury: Secondary Analyses of a Double-blinded Placebo-controlled Study
Effects of Low-Level Light Therapy on Resting-State Connectivity Following Moderate Traumatic Brain Injury: Secondary Analyses of a Double-blinded Placebo-controlled Study Open
Patients with moderate traumatic brain injury who were administered low-level light therapy within 72 hours after injury showed increased resting-state brain connectivity as measured with functional MRI during the acute to subacute recover…
View article: Association of Biomarkers of Neuronal Injury and Inflammation With Insomnia Trajectories After Traumatic Brain Injury
Association of Biomarkers of Neuronal Injury and Inflammation With Insomnia Trajectories After Traumatic Brain Injury Open
Elevated plasma hsCRP and, surprisingly, lower GFAP were associated with adverse insomnia trajectories after TBI. Results support future prospective studies to examine their utility in guiding insomnia care after TBI. Further work is neede…
View article: Association of Head Injury with Late-Onset Epilepsy: Results from the Atherosclerosis Risk in Communities Cohort
Association of Head Injury with Late-Onset Epilepsy: Results from the Atherosclerosis Risk in Communities Cohort Open
Background and Objectives Late-onset epilepsy (LOE; i.e., epilepsy starting in later adulthood) affects a significant number of individuals. Head injury is also a risk factor for acquired epilepsy, but the degree to which prior head injury…
View article: Performance of the IMPACT and CRASH prognostic models for traumatic brain injury in a contemporary multicenter cohort: a TRACK-TBI study
Performance of the IMPACT and CRASH prognostic models for traumatic brain injury in a contemporary multicenter cohort: a TRACK-TBI study Open
OBJECTIVE The International Mission on Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) and Corticosteroid Randomization After Significant Head Injury (CRASH) prognostic models for mortality and outcome after tr…
View article: Transcranial Photobiomodulation and Chronic Traumatic Brain Injury
Transcranial Photobiomodulation and Chronic Traumatic Brain Injury Open
Traumatic brain injury (TBI) is a common cause of neurologic morbidity for which few effective therapies exist, especially during the chronic stage. A potential therapy for chronic TBI is transcranial photobiomodulation (tPBM). tPBM is a n…
View article: Isolated Traumatic Subarachnoid Hemorrhage on Head Computed Tomography Scan May Not Be Isolated: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study (TRACK-TBI) Study
Isolated Traumatic Subarachnoid Hemorrhage on Head Computed Tomography Scan May Not Be Isolated: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study (TRACK-TBI) Study Open
Isolated traumatic subarachnoid hemorrhage (tSAH) after traumatic brain injury (TBI) on head computed tomography (CT) scan is often regarded as a "mild" injury, with reduced need for additional workup. However, tSAH is also a predictor of …
View article: Posttraumatic Epilepsy and Dementia Risk
Posttraumatic Epilepsy and Dementia Risk Open
Importance Although both head injury and epilepsy are associated with long-term dementia risk, posttraumatic epilepsy (PTE) has only been evaluated in association with short-term cognitive outcomes. Objective To investigate associations of…
View article: Data-driven characterization of traumatic brain injury severity from clinical, neuroimaging, and blood-based indicators
Data-driven characterization of traumatic brain injury severity from clinical, neuroimaging, and blood-based indicators Open
The conventional clinical approach to characterizing traumatic brain injuries (TBIs) as mild, moderate, or severe using the Glasgow Coma Scale (GCS) total score has well-known limitations, prompting calls for more sophisticated strategies …
View article: Monitoring patients with severe traumatic brain injury
Monitoring patients with severe traumatic brain injury Open
View article: Issue Information
Issue Information Open