Ryo Fukuda
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View article: Perioperative Strategies to Reduce Occupational HIV Exposure in Head and Neck Microsurgical Reconstruction: A Case Report
Perioperative Strategies to Reduce Occupational HIV Exposure in Head and Neck Microsurgical Reconstruction: A Case Report Open
Complex head and neck reconstructive surgeries in patients living with human immunodeficiency virus (HIV) present unique risks of occupational bloodborne pathogen exposure. We report the case of a 63-year-old man with well-controlled, long…
View article: Retraction: Induction of Hypoxia-inducible Factor 1 Activity by Muscarinic Acetylcholine Receptor Signaling
Retraction: Induction of Hypoxia-inducible Factor 1 Activity by Muscarinic Acetylcholine Receptor Signaling Open
View article: Management of Circumferential Cervical Benign Symmetric Lipomatosis: A Case Report of Staged Surgical Resection
Management of Circumferential Cervical Benign Symmetric Lipomatosis: A Case Report of Staged Surgical Resection Open
Benign symmetric lipomatosis (BSL), or Madelung disease, is a rare condition characterized by non-encapsulated, symmetrical adipose tissue accumulation. Although uncommon, circumferential cervical involvement can pose a life-threatening ri…
View article: Lymph node macrophage-targeted interferon alpha boosts anticancer immune responses by regulating CD169-positive phenotype of macrophages
Lymph node macrophage-targeted interferon alpha boosts anticancer immune responses by regulating CD169-positive phenotype of macrophages Open
View article: End-to-end Simultaneous Speech Translation with Style Tags using Human Simultaneous Interpretation Data
End-to-end Simultaneous Speech Translation with Style Tags using Human Simultaneous Interpretation Data Open
View article: Skull base chordoma diagnosed by hypoglossal nerve palsy associated with fasciculations of the tongue
Skull base chordoma diagnosed by hypoglossal nerve palsy associated with fasciculations of the tongue Open
View article: Lymph node macrophage-targeted interferon alpha boosts anticancer immune responses by regulating CD169-positive phenotype of macrophages
Lymph node macrophage-targeted interferon alpha boosts anticancer immune responses by regulating CD169-positive phenotype of macrophages Open
Background CD169+ macrophages in lymph nodes (LNs) activate cytotoxic T lymphocytes (CTLs), which play a crucial role in anticancer immunity, through antigen presentation and co-stimulation by CD169. Interferon alpha (IFNα) is c…
View article: Analysis of hot carrier instability in a floating body cell
Analysis of hot carrier instability in a floating body cell Open
Hot carrier instability (HCI) in a floating body cell (FBC) has been investigated. The FBC is a dynamic random-access memory (DRAM) made entirely of a silicon-on-insulator (SOI)-MOS without a capacitor. For FBC realization, there is an inf…
View article: NAIST Simultaneous Speech Translation System for IWSLT 2024
NAIST Simultaneous Speech Translation System for IWSLT 2024 Open
This paper describes NAIST's submission to the simultaneous track of the IWSLT 2024 Evaluation Campaign: English-to-{German, Japanese, Chinese} speech-to-text translation and English-to-Japanese speech-to-speech translation. We develop a m…
View article: Mouse Type-I Interferon-Mannosylated Albumin Fusion Protein for the Treatment of Chronic Hepatitis
Mouse Type-I Interferon-Mannosylated Albumin Fusion Protein for the Treatment of Chronic Hepatitis Open
Although a lot of effort has been put into creating drugs and combination therapies against chronic hepatitis, no effective treatment has been established. Type-I interferon is a promising therapeutic for chronic hepatitis due to its excel…
View article: Complete response induced by hepatic arterial infusion chemotherapy in large advanced hepatocellular carcinoma invading the right atrium
Complete response induced by hepatic arterial infusion chemotherapy in large advanced hepatocellular carcinoma invading the right atrium Open
症例は80歳代男性．食思不振，右季肋部痛を主訴に受診．造影CTで肝右葉に長径140 mm大の右房内浸潤を伴う腫瘤を認め，肝細胞癌cStage III（T3N0M0，Vv3，右房内浸潤あり，門脈浸潤なし）と診断した．初期治療として肝動注化学療法（New FP療法）を選択し，4コース施行後右房内浸潤は消失し腫瘍は著明に縮小した．残存したviable lesionに対しTACE＋RFAを3回施行し完全奏効となった．RFA終了後1年半以上経過しても再発なく経過している．肝動注化学療…
View article: Tagged End-to-End Simultaneous Speech Translation Training using Simultaneous Interpretation Data
Tagged End-to-End Simultaneous Speech Translation Training using Simultaneous Interpretation Data Open
Simultaneous speech translation (SimulST) translates partial speech inputs incrementally. Although the monotonic correspondence between input and output is preferable for smaller latency, it is not the case for distant language pairs such …
View article: Improving Speech Translation Accuracy and Time Efficiency with Fine-tuned wav2vec 2.0-based Speech Segmentation
Improving Speech Translation Accuracy and Time Efficiency with Fine-tuned wav2vec 2.0-based Speech Segmentation Open
Speech translation (ST) automatically converts utterances in a source language into text in another language. Splitting continuous speech into shorter segments, known as speech segmentation, plays an important role in ST. Recent segmentati…
View article: NAIST-SIC-Aligned: an Aligned English-Japanese Simultaneous Interpretation Corpus
NAIST-SIC-Aligned: an Aligned English-Japanese Simultaneous Interpretation Corpus Open
It remains a question that how simultaneous interpretation (SI) data affects simultaneous machine translation (SiMT). Research has been limited due to the lack of a large-scale training corpus. In this work, we aim to fill in the gap by in…
View article: Supplementary Tables 1 - 2, Figures 1 - 7 from Energy Management by Enhanced Glycolysis in G<sub>1</sub>-phase in Human Colon Cancer Cells <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Tables 1 - 2, Figures 1 - 7 from Energy Management by Enhanced Glycolysis in G<sub>1</sub>-phase in Human Colon Cancer Cells <i>In Vitro</i> and <i>In Vivo</i> Open
PDF - 1735K, Table S1: Percentages of Fucci-HTC116 in S + G2 and G1 phases in mouse liver metastatic foci. Table S2: Numbers of MALDO-IMS measurement points in mouse liver metastatic foci. Figure S1: Frequency distribution of relative inte…
View article: Data from Energy Management by Enhanced Glycolysis in G<sub>1</sub>-phase in Human Colon Cancer Cells <i>In Vitro</i> and <i>In Vivo</i>
Data from Energy Management by Enhanced Glycolysis in G<sub>1</sub>-phase in Human Colon Cancer Cells <i>In Vitro</i> and <i>In Vivo</i> Open
Activation of aerobic glycolysis in cancer cells is well known as the Warburg effect, although its relation to cell- cycle progression remains unknown. In this study, human colon cancer cells were labeled with a cell-cycle phase-dependent …
View article: Supplementary Tables 1 - 2, Figures 1 - 7 from Energy Management by Enhanced Glycolysis in G<sub>1</sub>-phase in Human Colon Cancer Cells <i>In Vitro</i> and <i>In Vivo</i>
Supplementary Tables 1 - 2, Figures 1 - 7 from Energy Management by Enhanced Glycolysis in G<sub>1</sub>-phase in Human Colon Cancer Cells <i>In Vitro</i> and <i>In Vivo</i> Open
PDF - 1735K, Table S1: Percentages of Fucci-HTC116 in S + G2 and G1 phases in mouse liver metastatic foci. Table S2: Numbers of MALDO-IMS measurement points in mouse liver metastatic foci. Figure S1: Frequency distribution of relative inte…
View article: Data from Energy Management by Enhanced Glycolysis in G<sub>1</sub>-phase in Human Colon Cancer Cells <i>In Vitro</i> and <i>In Vivo</i>
Data from Energy Management by Enhanced Glycolysis in G<sub>1</sub>-phase in Human Colon Cancer Cells <i>In Vitro</i> and <i>In Vivo</i> Open
Activation of aerobic glycolysis in cancer cells is well known as the Warburg effect, although its relation to cell- cycle progression remains unknown. In this study, human colon cancer cells were labeled with a cell-cycle phase-dependent …
View article: Supplementary Figure S5 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S5 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Effects of GROα and CXCL8 on STAT3 activation in tumor cells, and the effect of AGP on tumor proliferation in tumor cells. Several tumor cells were incubated with GROα (1 ng/mL) or CXCL8 (1 ng/mL) for 24 h, followed by the determination of…
View article: Supplementary Figure S1 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S1 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Effects of AGP on PD-L1 expression and STAT signaling cascade in macrophages. HMDMs were incubated with the indicated concentrations of AGP for 24 h (A) or with AGP (1 mg/mL) for the indicated times (B), followed by the determination of PD…
View article: Supplementary Figure S2 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S2 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
RNA-seq transcriptome analysis of macrophages vs macrophages with AGP samples. The heat map represents the normalized gene level RNA-Seq expression data in TPM (Transcripts per Million) for 1204 significant genes (q-value < 0.05) between m…
View article: Supplementary Figure S4 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S4 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Effects of AGP-treated macrophage-conditioned medium on STAT3 activation in tumor cells. Several tumor cells were incubated with AGP-MCM for the indicated times, followed by the determination of p-STAT3, STAT3, and β-actin expression by we…
View article: Supplementary Figure S4 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S4 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Effects of AGP-treated macrophage-conditioned medium on STAT3 activation in tumor cells. Several tumor cells were incubated with AGP-MCM for the indicated times, followed by the determination of p-STAT3, STAT3, and β-actin expression by we…
View article: Supplementary Figure S5 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S5 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Effects of GROα and CXCL8 on STAT3 activation in tumor cells, and the effect of AGP on tumor proliferation in tumor cells. Several tumor cells were incubated with GROα (1 ng/mL) or CXCL8 (1 ng/mL) for 24 h, followed by the determination of…
View article: Supplementary Figure S6 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S6 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Effect of AGP on PD-L1 expression and STAT3 activation in both mouse macrophages and mouse tumor cells. Mouse peritoneal macrophages were incubated with AGP (1 mg/mL) for 24 h, followed by the determination of PD-L1 expression by western b…
View article: Data from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Data from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Blood levels of acute-phase protein α1-acid glycoprotein (AGP, orosmucoid) increase in patients with cancer. Although AGP is produced from hepatocytes following stimulation by immune cell–derived cytokines under conditions of in…
View article: Supplementary Figure S2 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S2 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
RNA-seq transcriptome analysis of macrophages vs macrophages with AGP samples. The heat map represents the normalized gene level RNA-Seq expression data in TPM (Transcripts per Million) for 1204 significant genes (q-value < 0.05) between m…
View article: Supplementary Figure S3 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S3 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Involvement of IL-6R in AGP-MCM-induced STAT3 activation in tumor cells. IL-6R expression in macrophages and several tumor cells were determined by western blot analysis (A). HMDMs were incubated with IL-6 (10 ng/mL) and soluble IL-6R (20 …
View article: Supplementary Figure S7 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S7 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Effect of macrophage depletion on tumor development in AGP-treated tumor-bearing mouse model. AGP (2 mg/mouse) was administered to LM8 bearing C3H HeN mice treated with clodronate liposome to deplete macrophages, followed by the determinat…
View article: Supplementary Figure S7 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages
Supplementary Figure S7 from α<sub>1</sub>-Acid Glycoprotein Enhances the Immunosuppressive and Protumor Functions of Tumor-Associated Macrophages Open
Effect of macrophage depletion on tumor development in AGP-treated tumor-bearing mouse model. AGP (2 mg/mouse) was administered to LM8 bearing C3H HeN mice treated with clodronate liposome to deplete macrophages, followed by the determinat…