Gurusamy Raman
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View article: Isolation of Natural Veratrylidenehydrazide Compound from <i>Wedelia Biflora</i> and Synthesis of Veratrylidenehydrazide Analogue: Investigation of Larvicidal Activity Against <i>Culex Quinquefasciatus</i> and Toxicity Analysis in Nontarget Aquatic Species
Isolation of Natural Veratrylidenehydrazide Compound from <i>Wedelia Biflora</i> and Synthesis of Veratrylidenehydrazide Analogue: Investigation of Larvicidal Activity Against <i>Culex Quinquefasciatus</i> and Toxicity Analysis in Nontarget Aquatic Species Open
In this study, veratrylidenehydrazide was isolated from Wedelia biflora , and compounds ( 1a , 2a , and 3a–j ) were synthesised to evaluate their larvicidal and antifeedant activities. Veratrylidenehydrazide 1a was verified using GC‐MS. Th…
View article: Biofilm formation and antibiogram profile of bacteria from infected wounds in a general hospital in southern Ethiopia
Biofilm formation and antibiogram profile of bacteria from infected wounds in a general hospital in southern Ethiopia Open
Biofilm-producing bacteria associated with wound infections exhibit exceptional drug resistance, leading to an escalation in morbidity, worse clinical outcomes (including delay in the healing process), and an increase in health care cost, …
View article: Cu(II)-tyrosinase enzyme catalyst mediated synthesis of mosquito larvicidal active pyrazolidine-3,5-dione derivatives with molecular docking studies and their ichthyotoxicity analysis
Cu(II)-tyrosinase enzyme catalyst mediated synthesis of mosquito larvicidal active pyrazolidine-3,5-dione derivatives with molecular docking studies and their ichthyotoxicity analysis Open
The objective of this study was to develop pyrazolidine-3,5-dione derivatives with potential as environmentally friendly pesticides for pest control, specifically focusing on their efficacy as larvicidal agents. A novel one-pot synthesis o…
View article: Typical pneumonia among human immunodeficiency virus-infected patients in public hospitals in southern Ethiopia
Typical pneumonia among human immunodeficiency virus-infected patients in public hospitals in southern Ethiopia Open
Background Typical pneumonia is a pressing issue in the treatment of human immunodeficiency virus (HIV) patients, especially in Sub-Saharan Africa, where it remains a significant menace. Addressing this problem is crucial in improving heal…
View article: Aerobic vaginitis, bacterial vaginosis, and vaginal candidiasis among women of reproductive age in Arba Minch, southern Ethiopia
Aerobic vaginitis, bacterial vaginosis, and vaginal candidiasis among women of reproductive age in Arba Minch, southern Ethiopia Open
View article: Aerobic oxidation of aliphatic alcohol in cotton surface using epigallocatechin-3-gallate-iron (II, III) oxide (EGCG-Fe <sub>3</sub> O <sub>4</sub> ) nanocatalyst from green tea extract
Aerobic oxidation of aliphatic alcohol in cotton surface using epigallocatechin-3-gallate-iron (II, III) oxide (EGCG-Fe <sub>3</sub> O <sub>4</sub> ) nanocatalyst from green tea extract Open
This study involved the synthesis of epigallocatechin-3-gallate-Iron (II, III) oxide (EGCG- Fe3O4) nanocatalysts by reacting Fe2O3 with EGCG extracted from green tea (Camellia sinensis) aqueous e…
View article: Understanding a point mutation signature D54K in the caspase activation recruitment domain of NOD1 capitulating concerted immunity via atomistic simulation
Understanding a point mutation signature D54K in the caspase activation recruitment domain of NOD1 capitulating concerted immunity via atomistic simulation Open
Point mutation D54K in the human N-terminal caspase recruitment domain (CARD) of nucleotide-binding oligomerization domain −1 (NOD1) abrogates an imperative downstream interaction with receptor-interacting protein kinase (RIPK2) that entai…
View article: Synthesis of a New Series of Anthraquinone-Linked Cyclopentanone Derivatives: Investigating the Antioxidant, Antibacterial, Cytotoxic and Tyrosinase Inhibitory Activities of the Mushroom Tyrosinase Enzyme Using Molecular Docking
Synthesis of a New Series of Anthraquinone-Linked Cyclopentanone Derivatives: Investigating the Antioxidant, Antibacterial, Cytotoxic and Tyrosinase Inhibitory Activities of the Mushroom Tyrosinase Enzyme Using Molecular Docking Open
All synthesized compounds displayed remarkable antibacterial, tyrosinase inhibitory, antioxidant, and cytotoxic activities, with compound 2 showing exceptional potency as a multitarget agent. Anthraquinone substituent groups may off…
View article: Synthesis of anthraquinone-connected coumarin derivatives via grindstone method and their evaluation of antibacterial, antioxidant, tyrosinase inhibitory activities with molecular docking, and DFT calculation studies
Synthesis of anthraquinone-connected coumarin derivatives via grindstone method and their evaluation of antibacterial, antioxidant, tyrosinase inhibitory activities with molecular docking, and DFT calculation studies Open
View article: Mushroom tyrosinase enzyme catalysis: synthesis of larvicidal active geranylacetone derivatives against Culex quinquesfasciatus and molecular docking studies
Mushroom tyrosinase enzyme catalysis: synthesis of larvicidal active geranylacetone derivatives against Culex quinquesfasciatus and molecular docking studies Open
The grindstone process, which uses tyrosinase as a catalyst, was used to create analogues of geranylacetone. Tyrosinase was used to prepare the Mannich base under favourable reaction conditions, resulting in a high yield. All synthesized c…
View article: Population Structure and Genetic Diversity Analyses Provide New Insight into the Endemic Species Aster spathulifolius Maxim. and Its Evolutionary History
Population Structure and Genetic Diversity Analyses Provide New Insight into the Endemic Species Aster spathulifolius Maxim. and Its Evolutionary History Open
Aster spathulifolius, an ecologically significant plant species native to the coastal regions of Korea and Japan, remains understudied in terms of its genetic structure and evolutionary history. In this study, we employed four chloroplast …
View article: Cu (II)-catalyzed: synthesis of imidazole derivatives and evaluating their larvicidal, antimicrobial activities with DFT and molecular docking studies
Cu (II)-catalyzed: synthesis of imidazole derivatives and evaluating their larvicidal, antimicrobial activities with DFT and molecular docking studies Open
This paper deals with the evaluation of novel imidazole molecules for their antimicrobial and larvicidal activities. A series of imidazole derivatives 1(a – f) and 2(a – e) were prepared by the Mannich base technique using a Cu(II) catalys…
View article: Antioxidant, antibacterial, and cytotoxic activities of cimemoxin derivatives and their molecular docking studies
Antioxidant, antibacterial, and cytotoxic activities of cimemoxin derivatives and their molecular docking studies Open
Purpose: The cimemoxin derivatives and their biological importance in antioxidant, antibacterial, and cytotoxic activities were the main focus of this study. By using a one-step reaction and green chemistry method, this study was able to s…
View article: Spectroscopic studies on the antioxidant and anti-tyrosinase activities of anthraquinone derivatives
Spectroscopic studies on the antioxidant and anti-tyrosinase activities of anthraquinone derivatives Open
Objectives: Anthraquinones (9,10-dioxoantracenes) with a wide range of applications constitute an important class of natural and synthetic compounds. Moreover, there is an increasing interest in developing new anthraquinone derivatives wit…
View article: Synthesis and antibacterial activity of pyrano[3,2-g]chromene-4,6-dione derivatives and their molecular docking and DFT calculation studies
Synthesis and antibacterial activity of pyrano[3,2-g]chromene-4,6-dione derivatives and their molecular docking and DFT calculation studies Open
Pyran-4-one and chromenone are well known bioactive compounds, particularly antimicrobial activity. Present study investigation antibacterial activity of pyranone connected chromenone derivatives. New synthesis of pyrano[3,2-g]chromene-4,6…
View article: Factors Associated with Otitis Media Among Pediatrics in Two Government Hospitals in Arba Minch, Southern Ethiopia
Factors Associated with Otitis Media Among Pediatrics in Two Government Hospitals in Arba Minch, Southern Ethiopia Open
Overall, the prevalence of otitis media is showing an upward trend, and MDR among bacterial isolates is increasing alarmingly.
View article: Comparative Analysis and Identification of Terpene Synthase Genes in Convallaria keiskei Leaf, Flower and Root Using RNA-Sequencing Profiling
Comparative Analysis and Identification of Terpene Synthase Genes in Convallaria keiskei Leaf, Flower and Root Using RNA-Sequencing Profiling Open
The ‘Lilly of the Valley’ species, Convallaria, is renowned for its fragrant white flowers and distinctive fresh and green floral scent, attributed to a rich composition of volatile organic compounds (VOCs). However, the molecular mechanis…
View article: Extensive characterization of 28 complete chloroplast genomes of Hydrangea species: A perspective view of their organization and phylogenetic and evolutionary relationships
Extensive characterization of 28 complete chloroplast genomes of Hydrangea species: A perspective view of their organization and phylogenetic and evolutionary relationships Open
View article: The complete chloroplast genome sequence of <em>Acalypha</em> <em>australis</em>
The complete chloroplast genome sequence of <em>Acalypha</em> <em>australis</em> Open
The characterization of Acalypha australis chloroplast genome isolated from Busan, Republic of Korea.
View article: Extensive reorganization of the chloroplast genome of Corydalis platycarpa: A comparative analysis of their organization and evolution with other Corydalis plastomes
Extensive reorganization of the chloroplast genome of Corydalis platycarpa: A comparative analysis of their organization and evolution with other Corydalis plastomes Open
Introduction The chloroplast (cp) is an autonomous plant organelle with an individual genome that encodes essential cellular functions. The genome architecture and gene content of the cp is highly conserved in angiosperms. The plastome of …
View article: Vermiremediation: Analysis of contaminated diesel in soil using Eisenia fetida and ZnO nanoparticles with cow dung
Vermiremediation: Analysis of contaminated diesel in soil using Eisenia fetida and ZnO nanoparticles with cow dung Open
Cow dung is a valuable source of manure to improve soil quality. This study aims to enhance the soil quality by decreasing diesel contamination in the soil through the vermicomposting of cow dung and nanoparticles of ZnO. Using a powder ma…
View article: Structural Characterization and Comparative Analyses of the Chloroplast Genome of Eastern Asian Species Cardamine occulta (Asian C. flexuosa With.) and Other Cardamine Species
Structural Characterization and Comparative Analyses of the Chloroplast Genome of Eastern Asian Species Cardamine occulta (Asian C. flexuosa With.) and Other Cardamine Species Open
Background: Cardamine flexuosa is considered to be two separate species in the Cardamine genus based on their geographical distribution: European C. flexuosa and Eastern Asian C. flexuosa. These two species have not shown any morphological…
View article: Bis-(N-aminoethylethanolamine)-Copper(II) nanocatalysis (AEEA-Cu(II)-NPs) meditated to synthesis a series of 2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide derivatives: Characterization of theoretical, computational and evaluation of molecular docking, and cytotoxicity activities
Bis-(N-aminoethylethanolamine)-Copper(II) nanocatalysis (AEEA-Cu(II)-NPs) meditated to synthesis a series of 2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide derivatives: Characterization of theoretical, computational and evaluation of molecular docking, and cytotoxicity activities Open
In this work, bis-(N-aminoethylethanolamine)-Copper (II) nano (AEEA-Cu(II)-NPs) catalysis was synthesized and used as a catalyst in Biginelli reactions. Synthesized nanocatalysis was characterized by UV, FT-IR, XRD, SEM, and particle size …
View article: New Chitosan Polymer Scaffold Schiff Bases as Potential Cytotoxic Activity: Synthesis, Molecular Docking, and Physiochemical Characterization
New Chitosan Polymer Scaffold Schiff Bases as Potential Cytotoxic Activity: Synthesis, Molecular Docking, and Physiochemical Characterization Open
In this work, we synthesize the sulfonated Schiff bases of the chitosan derivatives 2a-2j without the use of a catalyst in two moderately straightforward steps with good yield within a short reaction time. The morphology and chemical struc…
View article: Euphorbia fauriei_jeju.gb
Euphorbia fauriei_jeju.gb Open
The complete chloroplast genome sequence of Euphorbia fauriei, isolated from Jeju Island, Republic of Korea.
View article: [Retracted] Nanobased Antibacterial Drug Discovery to Treat Skin Infections of Staphylococcus aureus Using Moringa oleifera‐Assisted Zinc Oxide Nanoparticle and Molecular Simulation Study
[Retracted] Nanobased Antibacterial Drug Discovery to Treat Skin Infections of Staphylococcus aureus Using Moringa oleifera‐Assisted Zinc Oxide Nanoparticle and Molecular Simulation Study Open
In addition to the physical barrier, the epidermis acts as a natural barrier against microbial proliferation. It is prone to bacterial infections on the skin and in the nose, such as Staphylococcus aureus, as well as a variety of other ski…
View article: The complete chloroplast genome of Euphorbia fauriei, isolated from Busan, Republic of Korea
The complete chloroplast genome of Euphorbia fauriei, isolated from Busan, Republic of Korea Open
The characterization of Euphorbia fauriei chloroplast genome, isolated from Busan, Republic of Korea.
View article: Potato Peels Mediated Synthesis of Cu(II)-nanoparticles from Tyrosinase Reacted with bis-(N-aminoethylethanolamine) (Tyr-Cu(II)-AEEA NPs) and Their Cytotoxicity against Michigan Cancer Foundation-7 Breast Cancer Cell Line
Potato Peels Mediated Synthesis of Cu(II)-nanoparticles from Tyrosinase Reacted with bis-(N-aminoethylethanolamine) (Tyr-Cu(II)-AEEA NPs) and Their Cytotoxicity against Michigan Cancer Foundation-7 Breast Cancer Cell Line Open
The synthesis of nanoparticles is most important in the context of cancer therapy, particularly copper nanoparticles, which are widely used. In this work, copper(II)-tyrosinase was isolated from potato peel powder. Copper nanoparticles (Ty…
View article: Tyrosinase-mediated synthesis of larvicidal active 1,5-diphenyl pent-4-en-1-one derivatives against Culex quinquefasciatus and investigation of their ichthyotoxicity
Tyrosinase-mediated synthesis of larvicidal active 1,5-diphenyl pent-4-en-1-one derivatives against Culex quinquefasciatus and investigation of their ichthyotoxicity Open
View article: The complete chloroplast genome of an endemic plant to Korea, <i>Cardamine amaraeformis</i> Nakai.: genome structure and phylogenetic analysis
The complete chloroplast genome of an endemic plant to Korea, <i>Cardamine amaraeformis</i> Nakai.: genome structure and phylogenetic analysis Open
The plant Cardamine amaraeformis Nakai. is considered an endemic plant to Korea. However, due to the similar morphological characteristics of C. amaraeformis with C. scutata, it is not easy to distinguish…