Explanipedia

Can machine learning models predict oocyte yield during assisted conception: a systematic review Open

Julie J. Wilkinson, Kanishka Gogna, Mary E. Gallagher, A. Richardson, Adam Devall , et al. · 2025

Preconception and first-trimester metformin on pregnancy outcomes in women with polycystic ovary syndrome: a systematic review and meta-analysis Open

James Cheshire, Akanksha Garg, Paul Smith, Adam Devall, Arri Coomarasamy , et al. · 2025

Continuing metformin treatment throughout the first trimester of pregnancy may reduce the risk of miscarriage and increase live birth rates in women with polycystic ovary syndrome. Continuation of metformin seems to have greater clinical b…

P-348 Artificial intelligence-based machine learning to diagnose and classify adenomyosis from ultrasound scans: a model development study Open

Isha Mishra, Nalini Mishra, Meng Qi, Madhurima Rajkhowa, Victoria Sephton , et al. · 2025

Study question Can an image recognition model, utilising automated deep learning, be trained to diagnose and classify the severity of adenomyosis on ultrasound? Summary answer The automated deep learning model developed in this study can a…

O-113 Tailoring treatment to ploidy: personalized approaches in (recurrent) pregnancy loss care Open

Rima Dhillon‐Smith · 2025

Recurrent pregnancy loss (RPL), also known as recurrent miscarriage (RM), is a devastating condition affecting approximately 2.5% of women trying to conceive. This condition is generally defined as the occurrence of two or more spontaneous…

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women Open

Yasir Elhassan, James Hawley, Leanne Cussen, Ali Abbara, Sophie Clarke , et al. · 2025

Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However se…

Management of Thyroid Disorders in Pregnancy Open

Shiao‐Yng Chan, M. S. Marsh, Jackie Gilbert, Kristien Boelaert, Carol Evans , et al. · 2025

Levothyroxine supplementation trials in preconception and pregnant women Open

Rebecca Man, Rima Dhillon‐Smith, Tim I.M. Korevaar · 2025

Thyroid disorders are common in women of childbearing age, representing the second most prevalent endocrine disorder in this population. Low thyroid function preconception and during pregnancy has been associated with a range of adverse ou…

The Association Between Periconceptual Maternal Dietary Patterns and Miscarriage Risk in Women With Recurrent Miscarriages: A Multicentre Cohort Study Open

Yealin Chung, Pedro Melo, Christina Easter, Malcolm J Price, Rima Dhillon‐Smith , et al. · 2024

Objective To examine the association between periconceptual maternal diet and miscarriage risk among women with recurrent miscarriages. Design Prospective multicentre cohort study (Tommy's Net). Setting Three university hospital research c…

Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis Open

J. Osinga, Yindi Liu, Tuija Männistö, Marina Vafeiadi, Fangbiao Tao , et al. · 2024

Background: International guidelines recommend targeted screening to identify gestational thyroid dysfunction. However, currently used risk factors have questionable discriminative ability. We quantified the risk for thyroid …

The association between periconceptual maternal dietary patterns and miscarriage risk in women with recurrent miscarriages: a multicentre cohort study Open

Yealin Chung, Pedro Melo, Christina Easter, Malcolm J Price, Rima Dhillon‐Smith , et al. · 2024

In a prospective multicentre cohort study across three UK university hospital research centres, we evaluated the association between periconceptual maternal dietary patterns and miscarriage risk among 1,035 women with recurrent miscarriage…

Table of Contents Open

Kirstin Barnhart, M Van, Wely Amsterdam, Haley N. Glatthorn, David McQueen , et al. · 2023

Genetic causes of sporadic and recurrent miscarriage Open

Pedro Melo, Rima Dhillon‐Smith, Md Asiful Islam, Adam Devall, Arri Coomarasamy · 2023

Approximately 80% of miscarriages happen within the first 12 weeks of gestation. More than half of early losses result from genetic defects, usually presenting as abnormal chromosome numbers or gene rearrangements in the embryo. However, t…

P-665 Timing of metformin treatment in women with polycystic ovarian syndrome and associated pregnancy outcomes: a systematic review and meta-analysis Open

James Cheshire, Akanksha Garg, Paul Smith, Arri Coomarasamy, Rima Dhillon‐Smith · 2023

Study question Does giving women with polycystic ovarian syndrome (PCOS) preconception metformin and continuing it through at least the first trimester improve pregnancy outcomes? Summary answer Giving women with PCOS preconception metform…

The association between dietary patterns and risk of miscarriage: a systematic review and meta-analysis Open

Yealin Chung, Pedro Melo, Oonagh Pickering, Rima Dhillon‐Smith, Arri Coomarasamy , et al. · 2023

CRD42020218133.

A core outcome set for trials in miscarriage management and prevention: An international consensus development study Open

Rima Dhillon‐Smith, Pedro Melo, Adam Devall, Paul Smith, M. Al‐Memar , et al. · 2023

Objective To develop core outcome sets (COS) for miscarriage management and prevention. Design Modified Delphi survey combined with a consensus development meeting. Setting International. Population Stakeholder groups included healthcare p…

Prevalence of adenomyosis in women with subfertility: systematic review and meta‐analysis Open

Ishita Mishra, Pedro Melo, Christina Easter, V. Sephton, Rima Dhillon‐Smith , et al. · 2023

Objective To determine the prevalence of adenomyosis in women with subfertility. Methods A systematic search was conducted in MEDLINE, EMBASE, CINAHL Plus, Google Scholar, PsycINFO and Web of Science Core Collection from database inception…

Morphological and morphokinetic associations with aneuploidy: a systematic review and meta-analysis Open

Thomas Bamford, Amy Barrie, Sue Montgomery, Rima Dhillon‐Smith, Alison Campbell , et al. · 2022

BACKGROUND A time lapse system (TLS) is utilized in some fertility clinics with the aim of predicting embryo viability and chance of live birth during IVF. It has been hypothesized that aneuploid embryos display altered morphokinetics as a…

The West Midland Familial Hypercholesterolaemia (FH) screening programme: Evaluating the utility of the 12 SNP polygenic risk score (PRS) across ethnic groupings Open

Elizabeth George, J. Bellaby, Shelley Day, Rima Dhillon‐Smith, Sean Horton , et al. · 2021

Sporadic miscarriage: evidence to provide effective care Open

Arri Coomarasamy, Ioannis Gallos, Argyro Papadopoulou, Rima Dhillon‐Smith, M. Al‐Memar , et al. · 2021

Recurrent miscarriage: evidence to accelerate action Open

Arri Coomarasamy, Rima Dhillon‐Smith, Argyro Papadopoulou, M. Al‐Memar, Jane Brewin , et al. · 2021

Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss Open

Siobhan Quenby, Ioannis Gallos, Rima Dhillon‐Smith, Marcelina Podesek, Mary D. Stephenson , et al. · 2021

Table of Contents Open

Rebecca Flyckt, Tommaso Falcone, Cristiano Quintini, Uma Perni, Bijan Eghtesad , et al. · 2020

The Prevalence of Thyroid Dysfunction and Autoimmunity in Women With History of Miscarriage or Subfertility Open

Rima Dhillon‐Smith, Aurelio Tobı́as, Paul Smith, Lee Middleton, Kirandeep K Sunner , et al. · 2020

Objective To describe the prevalence of and factors associated with different thyroid dysfunction phenotypes in women who are asymptomatic preconception. Design Observational cohort study. Setting A total of 49 hospitals across the United …

Micronized vaginal progesterone to prevent miscarriage: a critical evaluation of randomized evidence Open

Arri Coomarasamy, Adam Devall, Jan J. Brosens, Siobhan Quenby, Mary D. Stephenson , et al. · 2020

Progesterone is essential for the maintenance of pregnancy. Several small trials have suggested that progesterone supplementation may reduce the risk of miscarriage in women with recurrent or threatened miscarriage. Cochrane Reviews summar…

Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT Open

Rima Dhillon‐Smith, Lee Middleton, Kirandeep K Sunner, Versha Cheed, Krys Baker , et al. · 2019

Background Thyroid autoantibodies, specifically thyroid peroxidase antibodies, have been associated with miscarriage and pre-term birth in women with a normal thyroid function. Small randomised controlled trials have found that treatment w…

Vitamin D and assisted reproductive treatment outcome: a prospective cohort study Open

Justin Chu, Ioannis Gallos, Aurelio Tobı́as, Lauren Robinson, Jackson Kirkman‐Brown , et al. · 2019

OR11-1 A Randomized Trial of Preconception Levothyroxine in Euthyroid Women with Thyroid Peroxidase Antibodies Open

Rima Dhillon‐Smith, Lee Middleton, Kirandeep K Sunner, Versha Cheed, Krys Baker , et al. · 2019

BACKGROUND Thyroid peroxidase antibodies are associated with increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate levothyroxine could reduce such adverse outcomes. METHODS We conducte…

Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception Open

Rima Dhillon‐Smith, Lee Middleton, Kirandeep K Sunner, Versha Cheed, Krys Baker , et al. · 2019

The use of levothyroxine in euthyroid women with thyroid peroxidase antibodies did not result in a higher rate of live births than placebo. (Funded by the United Kingdom National Institute for Health Research; TABLET Current Controlled Tri…

An Invitation to Collaborate in the Consortium on Thyroid and Pregnancy Open

Tim I.M. Korevaar, Rima Dhillon‐Smith, Arri Coomarasamy, Robin P. Peeters · 2019

Core Outcome Sets in Miscarriage Trials (COSMisT) study: a study protocol Open

Paul Smith, N Cooper, Rima Dhillon‐Smith, Emily O’Toole, T. Justin Clark , et al. · 2017

Introduction ‘Core outcome sets’ are an agreed, standardised set of outcomes based on what key stakeholders (clinicians, patients, their partners, researchers, service developers, funding organisations and so on) consider the important out…

Rima Dhillon‐Smith YOU? Author Swipe