R. Gupta
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View article: Predictors of Response to Imatinib Therapy and Long‐Term Outcomes in Paediatric and Adolescent Patients With Chronic Myeloid Leukaemia
Predictors of Response to Imatinib Therapy and Long‐Term Outcomes in Paediatric and Adolescent Patients With Chronic Myeloid Leukaemia Open
Background Chronic myeloid leukaemia (CML) is an infrequent myeloproliferative neoplasm in the paediatric population as compared to adults. Despite vast progress in understanding the disease biology and therapy of CML‐chronic phase (CML CP…
View article: Development of ex vivo patient-derived models to uncover the role of the tumor immune microenvironment in renal cell carcinoma 4463
Development of ex vivo patient-derived models to uncover the role of the tumor immune microenvironment in renal cell carcinoma 4463 Open
Description With the rise of immune checkpoint inhibitors (ICIs) for the treatment of metastatic renal cell carcinoma (RCC), understanding the role of T cells in the tumor microenvironment (TME) is critical. Single-cell transcriptomics hav…
View article: Clinical Profile and Treatment Outcomes in Paediatric and Adult Acute Promyelocytic Leukemia: Experience from a Tertiary Care Centre in Northern India
Clinical Profile and Treatment Outcomes in Paediatric and Adult Acute Promyelocytic Leukemia: Experience from a Tertiary Care Centre in Northern India Open
Introduction: Acute promyelocytic leukemia (APL) is a distinct and highly curable subtype of acute myeloid leukemia. However, early mortality due to hemorrhage, differentiation syndrome (DS), and infections remains a significant challenge,…
View article: Lipid Dysregulation in Sepsis: A Prognostic Marker for Mortality and Organ Dysfunction
Lipid Dysregulation in Sepsis: A Prognostic Marker for Mortality and Organ Dysfunction Open
BACKGROUND: Sepsis is a life-threatening condition characterized by systemic inflammation and organ dysfunction, with significant morbidity and mortality rates. Alterations in lipid metabolism, particularly reductions in cholesterol, HDL, …
View article: HAPUSHADIYAPANA BASTI: AN AYURVEDIC APPROACH TO HOLISTIC HEALTH
HAPUSHADIYAPANA BASTI: AN AYURVEDIC APPROACH TO HOLISTIC HEALTH Open
Basti is a medical practice in Ayurveda when the medicine is administered anally. In ancient times, doctors would administer medicinal emesis using the urine bladders of sheep, cows, and buffalo. Acharya Charka consideredBasti as Ardha chi…
View article: G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds
G-protein-coupled receptor 84 regulates acute inflammation in normal and diabetic skin wounds Open
Lipids have emerged as potent regulators of immune cell function. In the skin, adipocyte lipolysis increases the local pool of free fatty acids and is essential for coordinating early macrophage inflammation following injury. Here, we inve…
View article: The mental health burden of food allergies: Insights from patients and their caregivers from the Food Allergy Research & Education (FARE) Patient Registry
The mental health burden of food allergies: Insights from patients and their caregivers from the Food Allergy Research & Education (FARE) Patient Registry Open
Our study highlights a continuing unmet need for mental health screening and support as part of the management of patients with food allergies.
View article: To Analyse and Compare Changes in Corrected Carotid Flow Time in Response to Fluid Challenge in Undifferentiated Shock
To Analyse and Compare Changes in Corrected Carotid Flow Time in Response to Fluid Challenge in Undifferentiated Shock Open
INTRODUCTION: Uncorrected hypovolemia and fluid overload may result in detrimental consequences. Measurement of corrected carotid flow time (ccFT) using point-of-care ultrasound (POCUS) has been proposed as a feasible, non-invasive means o…
View article: The clinical burden of food allergies: Insights from the Food Allergy Research & Education (FARE) Patient Registry
The clinical burden of food allergies: Insights from the Food Allergy Research & Education (FARE) Patient Registry Open
This is the first study to assess patient experience and disease burden information from patients contributing to the FARE Patient Registry, thus providing a unique insight into the lives of patients in the United States with food allergie…
View article: Reported food-related symptoms and food allergen sensitization in a selected adult population in Hyderabad, India: A hospital-based survey
Reported food-related symptoms and food allergen sensitization in a selected adult population in Hyderabad, India: A hospital-based survey Open
In this sample of South Indian adults diagnosed with allergic disease, reported food triggers were most commonly local dietary staples, while reported reactions to priority allergens like peanut and sesame were conspicuously absent. Observ…
View article: A STUDY ON SENTIMENT ANALYSIS TECHNIQUES OF TWITTER DATA
A STUDY ON SENTIMENT ANALYSIS TECHNIQUES OF TWITTER DATA Open
Nowadays a huge amount of data is being produced on web platforms .The Internet has become a podium for E-Learning, exchanging ideas and spreading opinions.Social networking platforms like Twitter, Facebook, Google are swiftly gaining mark…
View article: Total Serum Immunoglobulin E is Higher in African than European American Children with Food Allergy
Total Serum Immunoglobulin E is Higher in African than European American Children with Food Allergy Open
Background: The effect of race, age, sex, atopy, environmental exposures, and social determinants of health on total serum immunoglobulin E (IgE) has not been examined in children with food allergy. Method: We conducted a cross-sectional a…