Rashmi Sinha
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View article: Faecal sample collection for gut microbiome research in a prospective cohort: a pilot study within the Australian Breakthrough Cancer Study
Faecal sample collection for gut microbiome research in a prospective cohort: a pilot study within the Australian Breakthrough Cancer Study Open
Large prospective analyses of human gut microbiome profiles are needed to elucidate the role of microbiome variation in the development of disease. We conducted a pilot study to assess the feasibility of home faecal sample collection withi…
View article: Supplemental Table 1 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence
Supplemental Table 1 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence Open
Supplemental Table 1 shows the stability of microbiome metrics across three study timepoints in the four-year Polyp Prevention Trial, 1991-1998
View article: Supplemental Figure 1 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence
Supplemental Figure 1 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence Open
Supplementary Figure 1 alpha diversity according to whether the sample was collected before or after colonoscopy
View article: Supplemental Table 5 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence
Supplemental Table 5 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence Open
Supplemental Table 5 shows the cross-sectional and prospective multivariablea associations of a priori selected bacteria at three timepoints with adenoma recurrence in the four-year Polyp Prevention Trial, 1991-1998
View article: Supplementary Table 7 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods
Supplementary Table 7 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods Open
ICCs based on the relative abundance of the top 20 genus for microbiome stability comparing oral samples extracted upon receipt (baseline), after a year stored at -80°C (year 1), and after two years stored at -80°C (year 2) for two oral sa…
View article: Supplementary Table 6 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods
Supplementary Table 6 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods Open
ICCs based on random effects models for microbiome stability comparing oral samples extracted upon receipt (baseline), after a year stored at -80°C (year 1), and after two years stored at -80°C (year 2) for two oral sample collection metho…
View article: Supplemental Table 4 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence
Supplemental Table 4 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence Open
Supplemental Table 4 shows the cross-sectional multivariablea associations of baseline and year-1 alpha diversity with adenoma/polyp characteristics in the four-year Polyp Prevention Trial, 1991-1998
View article: Supplementary Table 5 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods
Supplementary Table 5 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods Open
ICCs based on the relative abundance of the top 20 genus for microbiome stability comparing fecal samples extracted upon receipt (baseline), after a year stored at -80°C (year 1), and after two years stored at -80°C (year 2) for five fecal…
View article: Supplemental Table 6 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence
Supplemental Table 6 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence Open
Supplemental Table 6 shows the exploratory analysis of cross-sectional and prospective multivariablea associations of select bacteria at three timepoints with adenoma recurrence in the four-year Polyp Prevention Trial, 1991-1998
View article: Supplementary Table 4 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods
Supplementary Table 4 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods Open
ICCs based on the relative abundances of the three most dominant phyla, three alpha diversity metrics (observed OTUs, Shannon Diversity, and Faith’s Phylogenetic Diversity) and three beta diversity metrics (Bray-Curtis, unweighted UniFrac,…
View article: Supplementary Methods from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence
Supplementary Methods from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence Open
Includes additional methodological information.
View article: Supplementary Table 8 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods
Supplementary Table 8 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods Open
Differential abundance analysis using the Wilcoxon signed-rank test to identify bacterial taxa at the phylum, family, and genus level which were differentially abundant (FDR < 0.05) among baseline, year 1, and year 2 for each collection me…
View article: Supplementary Table 2 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods
Supplementary Table 2 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods Open
ICCs based on the relative abundances of the three most dominant phyla, three alpha diversity metrics (observed OTUs, Shannon Diversity, and Faith’s Phylogenetic Diversity) and three beta diversity metrics (Bray-Curtis, unweighted UniFrac,…
View article: Supplementary Table 1 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods
Supplementary Table 1 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods Open
ICCs based on the relative abundances of the three most dominant phyla, three alpha diversity metrics (observed OTUs, Shannon Diversity, and Faith’s Phylogenetic Diversity) and three beta diversity metrics (Bray-Curtis, unweighted UniFrac,…
View article: Supplemental Figure 2 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence
Supplemental Figure 2 from Prospective and Cross-sectional Associations of the Rectal Tissue Microbiome with Colorectal Adenoma Recurrence Open
Supplementary Figure 2 shows associations of relative abundance of a priori-selected bacteria with adenomas
View article: Supplementary Table 3 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods
Supplementary Table 3 from Stability of the Fecal and Oral Microbiome over 2 Years at −80°C for Multiple Collection Methods Open
ICCs based on the relative abundances of the three most dominant phyla, three alpha diversity metrics (observed OTUs, Shannon Diversity, and Faith’s Phylogenetic Diversity) and three beta diversity metrics (Bray-Curtis, unweighted UniFrac,…
View article: 8278855 Occupational pesticide use and colon cancer in the agricultural health study, 1993–2021
8278855 Occupational pesticide use and colon cancer in the agricultural health study, 1993–2021 Open
View article: Meat Consumption in Relation to Colorectal Cancer Incidence in Anatomical Subsites in the National Institutes of Health-AARP Diet and Health Study
Meat Consumption in Relation to Colorectal Cancer Incidence in Anatomical Subsites in the National Institutes of Health-AARP Diet and Health Study Open
We found that replacing white meat with red meat was associated with higher CRC incidence. The lack of independent inverse associations for white meat intake indicates that lower CRC incidence is derived from lower red meat intake.
View article: Alcohol consumption and upper aerodigestive tract squamous cell carcinoma: evidence from 28 prospective cohorts
Alcohol consumption and upper aerodigestive tract squamous cell carcinoma: evidence from 28 prospective cohorts Open
Background This study aimed to investigate the association between alcohol consumption and squamous cell cancers of the upper aerodigestive tract (UADT), using data from 28 cohorts within the Pooling Project of Prospective Studies of Diet …
View article: Data from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies
Data from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies Open
Background:Stool cards have been used for microbiome assessment in epidemiologic studies.Methods:We compared shotgun metagenomic sequencing from 32 participants who self-collected stool samples from the same bowel movement using a custom s…
View article: Supplementary Table 2 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies
Supplementary Table 2 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies Open
Supplementary Table 2
View article: Supplementary Table 3 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies
Supplementary Table 3 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies Open
Supplementary Table 3
View article: Supplementary Methods from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies
Supplementary Methods from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies Open
Supplementary Methods
View article: Supplementary Figure 1 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies
Supplementary Figure 1 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies Open
Supplemental Figure 1. The picture of the custom stool card used for the study.
View article: Supplementary Table 1 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies
Supplementary Table 1 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies Open
Supplementary Table 1
View article: Supplementary Figure 2 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies
Supplementary Figure 2 from Comparing the Metagenomic Performance of Stools Collected from Custom Cards and 95% Ethanol in Epidemiologic Studies Open
Supplemental Figure 2. Correlation of the mean relative abundance of functional profiles assessed in the paired stool card and 95% ethanol samples from the same participants.
View article: Supplementary Figures 1-7 from Trends in Cancer Incidence and Mortality Rates in Early-Onset and Older-Onset Age Groups in the United States, 2010–2019
Supplementary Figures 1-7 from Trends in Cancer Incidence and Mortality Rates in Early-Onset and Older-Onset Age Groups in the United States, 2010–2019 Open
Supplemental Figure 1. Age-standardized cancer incidence (2010-2019) rates by age group and sex in the United States for a) melanoma, b) stomach cancer, c) colon and rectum cancer, d) kidney cancer, e) pancreas cancer, f) bones and joints …
View article: Supplementary Tables from Trends in Cancer Incidence and Mortality Rates in Early-Onset and Older-Onset Age Groups in the United States, 2010–2019
Supplementary Tables from Trends in Cancer Incidence and Mortality Rates in Early-Onset and Older-Onset Age Groups in the United States, 2010–2019 Open
Supplemental Table 1. Number of incident cancers by sex, cancer type and age group in U.S. Cancer Statistics, 2010-2019. Supplemental Table 2. Age-standardized incidence rates and annual percent changes in incidence rates in the United Sta…
View article: Data from Trends in Cancer Incidence and Mortality Rates in Early-Onset and Older-Onset Age Groups in the United States, 2010–2019
Data from Trends in Cancer Incidence and Mortality Rates in Early-Onset and Older-Onset Age Groups in the United States, 2010–2019 Open
We estimated age-standardized cancer incidence (2010–2019) and mortality rates (2010–2022) in the United States to investigate whether cancer rates have increased at younger ages. Fourteen cancers had incidence rates that increased in at l…
View article: Identification and validation of poly-metabolite scores for diets high in ultra-processed food: An observational study and post-hoc randomized controlled crossover-feeding trial
Identification and validation of poly-metabolite scores for diets high in ultra-processed food: An observational study and post-hoc randomized controlled crossover-feeding trial Open
Background Ultra-processed food (UPF) accounts for a majority of calories consumed in the United States, but the impact on human health remains unclear. We aimed to identify poly-metabolite scores in blood and urine that are predictive of …