Explanipedia

Cost-Effective and High-Throughput LPS Detection via Microdroplet Technology in Biopharmaceuticals Open

Adriano Colombelli, Daniela Lospinoso, Valentina Arima, Vita Guarino, Alessandra Zizzari , et al. · 2025

Lipopolysaccharides (LPS) from Gram-negative bacteria represent a significant challenge across various industries due to their prevalence and pathogenicity and the limitations of existing detection methods. Traditional approaches, such as …

Controlling endotoxin contamination in PDMS-based microfluidic systems for organ-on-chip technologies Open

Vita Guarino, Elisabetta Perrone, Alessandra Zizzari, Monica Bianco, Gabriele Giancane , et al. · 2025

Sustainable and Flexible Surface-Enhanced Raman Scattering Transducer: Gold Nanoparticle-Bacterial Cellulose Composite for Pesticide Monitoring in Agrifood Systems Open

Daniela Lospinoso, Adriano Colombelli, Sudipto Pal, P. Cretı̀, Maria Concetta Martucci , et al. · 2025

Functionalized plasmonic nanostructure platforms are widely used for developing optical biosensors and SERS assays. In this work, we present a low-cost and scalable surface-enhanced Raman scattering (SERS) system based on an innovative opt…

Controlling Endotoxin Contamination in Pdms-Based Microfluidic Systems for Organ-on-Chip Technologies Open

Vita Guarino, Elisabetta Perrone, Alessandra Zizzari, Monica Bianco, Gabriele Giancane , et al. · 2025

Controlling Endotoxin Contamination in Pdms-Based Microfluidic Systems for Organ-on-Chip Technologies Open

Vita Guarino, Elisabetta Perrone, Alessandra Zizzari, Monica Bianco, Gabriele Giancane , et al. · 2025

Rational Design and Optimization of Plasmonic Nanohole Arrays for Sensing Applications Open

Daniela Lospinoso, Adriano Colombelli, R. Rella, Maria Grazia Manera · 2024

The design and optimization of plasmonic nanohole arrays (NHAs) as transducers for efficient bioanalytical sensing is a rapidly growing field of research. In this work, we present a rational method for tailoring the optical and functional …

Exploring Metal Nanostructures Magneto-Optical Properties as Innovative Local Refractive Index Transducers Open

Adriano Colombelli, Daniela Lospinoso, R. Rella, Maria Grazia Manera · 2024

Maximizing Fluorescence Enhancement in Metal Nanoantenna Arrays for efficient bioanalytical devices Open

Daniela Lospinoso, Adriano Colombelli, Arianna Cretı̀, Maura Cesaria, M. Lomascolo , et al. · 2024

Our investigation focused on fluorescence enhancement mechanisms using metal nanoantennas with Alexa Fluor-647. By exploiting numerical modelling tools, we fabricated non-interacting Au nanodisc arrays on glass substrates, achieving a maxi…

Tunable Nanoplasmonic Transducers: Performance Analysis and Potential Application Open

Adriano Colombelli, Daniela Lospinoso, R. Rella, Maria Grazia Manera · 2023

Plasmonic nanostructures with tunable optical properties can have many different applications, including high-sensitivity optical sensing for biological and chemical analyses in different field such as medical, environmental and food safet…

Shape Modulation of Plasmonic Nanostructures by Unconventional Lithographic Technique Open

Adriano Colombelli, Daniela Lospinoso, R. Rella, Maria Grazia Manera · 2022

Conventional nano-sphere lithography techniques have been extended to the fabrication of highly periodic arrays of sub-wavelength nanoholes in a thin metal film. By combining the dry etching processes of self-assembled monolayers of polyst…

Self-Assembled Metal Nanohole Arrays with Tunable Plasmonic Properties for SERS Single-Molecule Detection Open

Daniela Lospinoso, Adriano Colombelli, M. Lomascolo, R. Rella, Maria Grazia Manera · 2022

Arrays of metal nano-holes have proved to be among of the most promising structures for applications in the field of nano-photonics and optoelectronics. Supporting both localized and propagating surface plasmons resonances, they are charac…

Magnetophotonics for sensing and magnetometry toward industrial applications Open

Conrad Rizal, Maria Grazia Manera, Daria O. Ignatyeva, J. R. Mejía-Salazar, R. Rella , et al. · 2021

Magnetic nanostructures sustaining different types of optical modes have been used for magnetometry and label-free ultrasensitive refractive index probing, where the main challenge is the realization of compact devices that are able to tra…

Magnetophotonics for sensing and magnetometry towards industrial applications Open

Conrad Rizal, Maria Grazia Manera, Daria O. Ignatyeva, J. R. Mejía-Salazar, R. Rella , et al. · 2021

Magnetic nanostructures sustaining different kinds of optical modes have been used for magnetometry and label-free ultrasensitive refractive index probing, where the main challenge is the realization of compact devices able to transfer thi…

MagnetoPlasmonic Waves/HOMO-LUMO Free π-Electron Transitions Coupling in Organic Macrocycles and Their Effect in Sensing Applications Open

Maria Grazia Manera, Gabriele Giancane, Simona Bettini, Ludovico Valli, Victor Borovkov , et al. · 2021

Optical and magneto-optical surface plasmon resonance (MOSPR) characterization and preliminary sensing test onto single- and multi-layers of two organic macrocycles have been performed; TbPc2(OC11H21)8 phthalocyanine and CoCoPo2 porphyrin …

Monolayer colloidal lithography protocol: theoretical assessment and applicative potentialities for metal nanohole fabrication Open

Maura Cesaria, A. Taurino, Maria Grazia Manera, Simona Scarano, Maria Minunni , et al. · 2021

Polystyrene colloids adsorbed onto a poly(diallyldimethylammonium chloride) (PDDA) monolayer is the model-system exploited to present and discuss both theoretical assessment and extended practical roadmap of the monolayer colloidal lithogr…

Nanoplasmonic Biosensing Approach for Endotoxin Detection in Pharmaceutical Field Open

Adriano Colombelli, Elisabetta Primiceri, Silvia Rizzato, Anna Grazia Monteduro, Giuseppe Maruccio , et al. · 2021

The outer membrane of Gram-negative bacteria contains bacterial endotoxins known as Lipopolysaccharides (LPS). Owing to the strong immune responses induced in humans and animals, these large molecules have a strong toxic effect that can ca…

Peroxides and Bisphenols Detection in Extra Virgin Olive Oil (EVOO) by Plasmonic Nanodomes Transducers Open

Adriano Colombelli, Daniela Lospinoso, Maria Grazia Manera, R. Rella · 2020

Large-area nanostructured transducer for absorption opto-plasmonic measurements in the ultraviolet visible UV-VIS spectral range have been realized by colloidal lithography. The design and simulation performed guarantee the optical behavio…

Short-range ordered 2D nanoholes: lattice-model and novel insight into the impact of coordination geometry and packing on their propagating-mode transmittance features Open

Maura Cesaria, A. Taurino, Maria Grazia Manera, R. Rella · 2020

The lattice-model, periodicity length-scale and impact of the transition from quasi-hexagonal to quasi-cubic packing coordination geometry on the propagating-mode transmittance feature of short-range ordered metal nanoholes.

Mixing enhancement induced by viscoelastic micromotors in microfluidic platforms Open

Alessandra Zizzari, Maura Cesaria, Monica Bianco, Loretta L. del Mercato, Mauro Carraro , et al. · 2019

Long- and Short-Range Ordered Gold Nanoholes as Large-Area Optical Transducers in Sensing Applications Open

Maura Cesaria, Adriano Colombelli, Daniela Lospinoso, A. Taurino, Enrico Melissano , et al. · 2019

Unconventional lithography (such as nanosphere lithography (NSL) and colloidal lithography (CL)) is an attractive alternative to sequential and very expensive conventional lithography for the low-cost fabrication of large-area nano-optical…

Lab-on-a-brane for spheroid formation Open

Monica Bianco, Alessandra Zizzari, P Priore, Lorenzo Moroni, Pierangelo Metrangolo , et al. · 2019

Lab-On-a-Brane (LOB) represents a class of Lab-On-a-Chip (LOC) integrating flexible, highly gas permeable and biocompatible thin membranes (TMs). Here we demonstrate the potentiality of LOBs as cell biochips promoting 3D cell growth. The h…

Gold nanoholes fabricated by colloidal lithography: novel insights into nanofabrication, short-range correlation and optical properties Open

Maura Cesaria, A. Taurino, Maria Grazia Manera, Maria Minunni, Simona Scarano , et al. · 2019

A simplified colloidal lithography protocol (polyelectrolyte monolayer) for Au nanohole fabrication and autocorrelation/FFT analysis of SEM images to disclose hidden short-range periodicities.

Magneto-Optical properties of noble-metal nanostructures: functional nanomaterials for bio sensing Open

Maria Grazia Manera, Adriano Colombelli, A. Taurino, Antonio García‐Martín, R. Rella · 2018

Interaction-tailored organization of large-area colloidal assemblies Open

Silvia Rizzato, Elisabetta Primiceri, Anna Grazia Monteduro, Adriano Colombelli, Angelo Leo , et al. · 2018

Colloidal lithography is an innovative fabrication technique employing spherical, nanoscale crystals as a lithographic mask for the low cost realization of nanoscale patterning. The features of the resulting nanostructures are related to t…

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