Savina Nodari
YOU?
Author Swipe
Clinical and echocardiographic changes after intermittent levosimendan infusion in patients with advanced heart failure Open
Aims To evaluate the short-term clinical, structural, and functional cardiac changes following intermittent levosimendan infusion and their prognostic implications in patients with advanced heart failure (AdHF). Methods In this prospective…
View article: Breastfeeding and maternal exercise: A synergistic approach to improve cardiometabolic health
Breastfeeding and maternal exercise: A synergistic approach to improve cardiometabolic health Open
Healthcare providers should reassure postpartum women that moderate exercise is safe during lactation and encourage its integration into postpartum care. Future studies should explore high-intensity exercise, resistance training, and inter…
Heart failure and chronic obstructive pulmonary disease. A combination not to be underestimated Open
Chronic obstructive pulmonary disease (COPD) and heart failure (HF) frequently coexist and interact through complex and bidirectional hemodynamic mechanisms that amplify symptoms’ burden and complicate clinical management. The present revi…
View article: Lung ultrasound in cardiac rehabilitation: expert consensus on protocols, clinical use, and integration into patient management from the working group on cardiac rehabilitation and cardiovascular prevention of the Italian society of cardiology
Lung ultrasound in cardiac rehabilitation: expert consensus on protocols, clinical use, and integration into patient management from the working group on cardiac rehabilitation and cardiovascular prevention of the Italian society of cardiology Open
Lung ultrasonography (LUS) is a reliable and reproducible tool across various clinical settings. Its high diagnostic accuracy, portability, and real-time imaging capabilities make it especially suitable for use in Emergency Departments, In…
View article: Role of HFA-ICOS score in breast cancer and its relationship with left and right ventricular strain
Role of HFA-ICOS score in breast cancer and its relationship with left and right ventricular strain Open
Background Anthracycline cardiotoxicity is a significant complication of oncological therapy. Cardiovascular risk stratification is crucial to identify vulnerable patients. The HFA-ICOS score offers a standardized tool for categorizing bas…
View article: Cardiovascular toxicity in CML patients treated with BCR-ABL inhibitors: relevance of early detection and management of cardiovascular follow-up
Cardiovascular toxicity in CML patients treated with BCR-ABL inhibitors: relevance of early detection and management of cardiovascular follow-up Open
Background Chronic myeloid leukemia (CML) is a hematological malignancy driven by the BCR-ABL fusion gene, which has become the target of tyrosine kinase inhibitors (TKIs). These therapies have transformed CML outcomes, significantly impro…
View article: Snapshot of cardio-oncology practice in Italy
Snapshot of cardio-oncology practice in Italy Open
Background Several types of patients should be referred to cardio-oncology services, but some may prevail in clinical practice. Moreover, with the global aging of the population of industrialized countries, the patterns of cardio-oncology …
View article: Gender and Sex-related differences in Type 2 Myocardial Infarction: the undervalued side of a neglected disease
Gender and Sex-related differences in Type 2 Myocardial Infarction: the undervalued side of a neglected disease Open
Type 2 myocardial infarction (T2MI) occurs due to an imbalance between coronary blood supply and myocardial oxygen demand, leading to ischemia without the rupture of an atherosclerotic plaque, distinguishing it from Type 1 myocardial infar…
SGLT2 inhibitors promote electrical remodeling in heart failure patients undergoing cardiac resynchronization therapy: a clinical and metabolomic analysis Open
Background Recent randomized controlled trials have highlighted the significant prognostic benefits of sodium/glucose cotransporter 2 (SGLT2) inhibitors (SGLT2i) in heart failure (HF) patients. The DAPA-HF study demonstrated that dapaglifl…
View article: Implementation of guideline‐directed medical therapy in patients with heart failure with reduced ejection fraction (OpTIMa‐HF Registry)
Implementation of guideline‐directed medical therapy in patients with heart failure with reduced ejection fraction (OpTIMa‐HF Registry) Open
Aims The last released European guidelines on the management of heart failure (HF) recommend in patients with chronic HF with reduced ejection fraction (HFrEF) a pharmacological approach based on four fundamental drugs to be rapidly implem…
Heart failure outpatient clinics resources in Italy: a viewpoint of Italian Society of Cardiology organization Open
The current paper reports the model organization, level of health care, and type of medical and research activities related to the existing heart failure centers of the Italian Society of Cardiology. Of note, we conduced an internal survey…
View article: Prognostic role of TAPSE to PASP ratio in outpatients with left ventricular systolic dysfunction
Prognostic role of TAPSE to PASP ratio in outpatients with left ventricular systolic dysfunction Open
Aims Few data are available regarding the role of tricuspid annulus plane systolic excursion to pulmonary artery systolic pressure (TAPSE/PASP), a measurement of right ventricular to pulmonary artery coupling, in patients with chronic hear…
View article: AIHEMAF–P: An Innovative Healthcare Model for Atrial Fibrillation Patients
AIHEMAF–P: An Innovative Healthcare Model for Atrial Fibrillation Patients Open
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias of clinical relevance and a major cause of cardiovascular morbidity and mortality. Following a diagnosis of AF, patients are directed towards therapy with anticoagulant…
View article: Finerenone in Women and Men With Heart Failure With Mildly Reduced or Preserved Ejection Fraction
Finerenone in Women and Men With Heart Failure With Mildly Reduced or Preserved Ejection Fraction Open
Importance Sex is associated with the clinical presentation, outcomes, and response to treatment in patients with heart failure (HF). However, little is known about the safety and efficacy of treatment with finerenone according to sex. Obj…
View article: The chronic heart failure evolutions: Different fates and routes
The chronic heart failure evolutions: Different fates and routes Open
Aims Individual prognostic assessment and disease evolution pathways are undefined in chronic heart failure (HF). The application of unsupervised learning methodologies could help to identify patient phenotypes and the progression in each …
View article: Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction
Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction Open
In patients with heart failure and mildly reduced or preserved ejection fraction, finerenone resulted in a significantly lower rate of a composite of total worsening heart failure events and death from cardiovascular causes than placebo. (…
View article: Distinct Profiles and New Pharmacological Targets for Heart Failure with Preserved Ejection Fraction
Distinct Profiles and New Pharmacological Targets for Heart Failure with Preserved Ejection Fraction Open
Background: Heart failure with preserved ejection fraction (HFpEF) is a multifactorial condition with a variety of pathophysiological causes and morphological manifestations. The inclusion criteria and patient classification have become ov…
View article: Deceived by the Fick principle: blood flow distribution in heart failure
Deceived by the Fick principle: blood flow distribution in heart failure Open
Aims The Fick principle states that oxygen uptake (V̇O2) is cardiac output (Qc) * arterial-venous O2 content difference [ΔC(a-v)O2]. Blood flow distribution is hidden in Fick principle, and its relevance during exercise in heart failure (HF…
View article: Baseline Characteristics of Patients with Heart Failure with Mildly Reduced or Preserved Ejection Fraction: The FINEARTS-HF Trial
Baseline Characteristics of Patients with Heart Failure with Mildly Reduced or Preserved Ejection Fraction: The FINEARTS-HF Trial Open
Aims To describe the baseline characteristics of participants in the FINEARTS-HF trial, contextualized with prior trials including patients with heart failure (HF) with mildly reduced and preserved ejection fraction (HFmrEF/HFpEF). The FIN…
The Impact of Stress and Social Determinants on Diet in Cardiovascular Prevention in Young Women Open
The prevention of cardiovascular diseases is a fundamental pillar for reducing morbidity and mortality caused by non-communicable diseases. Social determinants, such as socioeconomic status, education, neighborhood, physical environment, e…
View article: Cardiovascular Biomarkers in Cardio-Oncology: Antineoplastic Drug Cardiotoxicity and Beyond
Cardiovascular Biomarkers in Cardio-Oncology: Antineoplastic Drug Cardiotoxicity and Beyond Open
Serum biomarkers represent a reproducible, sensitive, minimally invasive and inexpensive method to explore possible adverse cardiovascular effects of antineoplastic treatments. They are useful tools in risk stratification, the early detect…
View article: Effects of sacubitril/valsartan on renal function and outcome in patients with heart failure and reduced ejection fraction: an Italian cohort study
Effects of sacubitril/valsartan on renal function and outcome in patients with heart failure and reduced ejection fraction: an Italian cohort study Open
Background: Sacubitril/valsartan (S/V) is a cornerstone treatment for heart failure (HF). Beneficial effects on hospitalization rates, mortality, and left ventricular remodeling have been observed in patients with heart failure and reduced…
View article: Multimodality Imaging in Advanced Heart Failure for Diagnosis, Management and Follow-Up: A Comprehensive Review
Multimodality Imaging in Advanced Heart Failure for Diagnosis, Management and Follow-Up: A Comprehensive Review Open
Advanced heart failure (AHF) presents a complex landscape with challenges spanning diagnosis, management, and patient outcomes. In response, the integration of multimodality imaging techniques has emerged as a pivotal approach. This compre…
Role of telemedicine network provided by pharmacies to detect electrocardiographic changes deserving cardiological evaluation in young patients Open
Background cardiac arrhythmias affecting adolescents and young subjects are a wide-ranging problem. Often-such conditions, in addition to being highly varied and sometimes hard to diagnose, are largely silent and onset variably and suddenl…