R. Saikant
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View article: Evaluation of molecular effects associated with apoptosis, tumour progression, angiogenesis and metastasis by a novel combination of drugs with ormeloxifene in triple negative breast cancer cells
Evaluation of molecular effects associated with apoptosis, tumour progression, angiogenesis and metastasis by a novel combination of drugs with ormeloxifene in triple negative breast cancer cells Open
Aim: To investigate the molecular effects of a novel combination [sertraline and plumbagin (comb) with ormeloxifene (Orm)] for anticancer activity in triple negative breast cancer cell line “MDA-MB-231”. Methods: The cytotoxic effect of th…
View article: COVID-19: global pandemic with divergent waves: an exigent public health concern worldwide with special context to Indian scenario
COVID-19: global pandemic with divergent waves: an exigent public health concern worldwide with special context to Indian scenario Open
The review discusses, how the COVID-19 virus evolved to the present form, genome organization and genetic variation of SARS- CoV-2 prevalent globally with special emphasis on Indian strains, a comparison of the first vs. second wave in ter…
View article: Comparative differential cytotoxicity of clinically used SERMs in human cancer lines of different origin and its predictive molecular docking studies of key target genes involved in cancer progression and treatment responses
Comparative differential cytotoxicity of clinically used SERMs in human cancer lines of different origin and its predictive molecular docking studies of key target genes involved in cancer progression and treatment responses Open
View article: The prevalence of enteroviral RNA and protein in mitral valves of chronic rheumatic heart disease
The prevalence of enteroviral RNA and protein in mitral valves of chronic rheumatic heart disease Open
Introduction: Acute Rheumatic Fever/ Rheumatic Heart Disease (ARF/RHD), a sequel of group A streptococcal (GAS) infection, even today constitutes a public health issue in developing countries including India. Differences in the prevalence …
View article: Effect of lyophilization on HRP–antibody conjugation: an enhanced antibody labeling technology
Effect of lyophilization on HRP–antibody conjugation: an enhanced antibody labeling technology Open
After confirming chemical modification of conjugates via UV-Spec and SDS-PAGE independent molecules were used for conjugation and HRP-antibody conjugate. Finally, enzymatic activity of HRP-antibody conjugate was confirmed by performing dir…
View article: Response of letter to the editor on Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy
Response of letter to the editor on Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy Open
In a letter to the editor, Raineri SM et al. have given an insight of another dimension of procalcitonin (PCT) use as a diagnostic tool in invasive candidiasis. But based on our preliminary information, PCT is reported as unconventional mo…
View article: Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy
Procalcitonin: a promising diagnostic marker for sepsis and antibiotic therapy Open