Kenneth J. Sher
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View article: Synthetic lethality of mRNA quality control complexes in cancer
Synthetic lethality of mRNA quality control complexes in cancer Open
View article: “General Addiction Liability” Revisited
“General Addiction Liability” Revisited Open
Although substance use disorders are widely known to be influenced by myriad etiologic factors, recent research promotes the notion that liability toward addiction broadly construed can be described by a single, unitary dimension that we t…
View article: Correction: Age Specificity of Effects of Health Problems on Drinking Reduction: A Lifespan Developmental Analysis
Correction: Age Specificity of Effects of Health Problems on Drinking Reduction: A Lifespan Developmental Analysis Open
View article: Psychopathology as dynamic markers of alcohol initiation across development: A three-year longitudinal examination
Psychopathology as dynamic markers of alcohol initiation across development: A three-year longitudinal examination Open
Sipping, an early form of alcohol initiation, is associated with aspects of psychopathology and personality that reflect long-term risk for harmful alcohol use. In the Adolescent Brain and Cognitive Development cohort ( N = 11,872), sippin…
View article: Alcohol use disorder criteria exhibit different comorbidity patterns
Alcohol use disorder criteria exhibit different comorbidity patterns Open
Background and aims Alcohol use disorder is comorbid with numerous other forms of psychopathology, including externalizing disorders (e.g. conduct disorder) and, to a lesser extent, internalizing conditions (e.g. depression, anxiety). Much…
View article: Self-report assessment of alcohol sensitivity: An examination of the effects of different probes.
Self-report assessment of alcohol sensitivity: An examination of the effects of different probes. Open
Assessments of sensitivity should probe for minimum and maximum number of drinks across each of the effects. If impractical to probe for both, consistently probing for maximum number of drinks is desirable. (PsycInfo Database Record (c) 20…
View article: A life span developmental investigation of marriage and problem-drinking reduction
A life span developmental investigation of marriage and problem-drinking reduction Open
While prior literature has largely focused on marriage effects during young adulthood, it is less clear whether these effects are as strong in middle adulthood. Thus, we investigated age differences in marriage effects on problem-drinking …
View article: Contextual decision-making and alcohol use disorder criteria: Delayed reward, delayed loss, and probabilistic reward discounting.
Contextual decision-making and alcohol use disorder criteria: Delayed reward, delayed loss, and probabilistic reward discounting. Open
These results support the idea that AUD criteria are etiologically distinct, resulting in varying AUD profiles between persons that are differentially associated with behavioral economic discounting. (PsycInfo Database Record (c) 2023 APA,…
View article: Cross-sectional and longitudinal AUD symptom networks: They tell different stories
Cross-sectional and longitudinal AUD symptom networks: They tell different stories Open
View article: Individual-, peer-, and parent-level substance use-related factors among 9- and 10-year-olds from the ABCD Study: Prevalence rates and sociodemographic differences
Individual-, peer-, and parent-level substance use-related factors among 9- and 10-year-olds from the ABCD Study: Prevalence rates and sociodemographic differences Open
This study identified substance use-related individual-, peer-, and parent-level factors among a diverse, national sample. Findings highlight the importance of considering sociodemographic and substance-specific variability and may help id…
View article: How Robust Is the p Factor? Using Multitrait-Multimethod Modeling to Inform the Meaning of General Factors of Youth Psychopathology
How Robust Is the p Factor? Using Multitrait-Multimethod Modeling to Inform the Meaning of General Factors of Youth Psychopathology Open
We used multitrait-multimethod (MTMM) modeling to examine general factors of psychopathology in three samples of youths ( Ns = 2,119, 303, and 592) for whom three informants reported on the youth’s psychopathology (e.g., child, parent, tea…
View article: Older Adult Health and Remission of Risky Drinking and Alcohol Use Disorder: A Lifespan-Developmental Study
Older Adult Health and Remission of Risky Drinking and Alcohol Use Disorder: A Lifespan-Developmental Study Open
Older-adult drinking is a growing public-health concern. As part of a larger project investigating older adulthood by contrasting this with other adult developmental periods, this study used longitudinal U.S.-representative data to test bi…
View article: A mixed-method evaluation of the adoption and implementation of the College Alcohol Intervention Matrix among prevention experts: a study protocol
A mixed-method evaluation of the adoption and implementation of the College Alcohol Intervention Matrix among prevention experts: a study protocol Open
Background Risky drinking among college campuses has been a long-standing concern and there have been dedicated efforts to develop evidence-based prevention and treatment strategies (EBSs) to decrease alcohol use and increase healthy behav…
View article: Age Effect on the Bidirectional Relations Between Alcohol Consumption and Pain
Age Effect on the Bidirectional Relations Between Alcohol Consumption and Pain Open
Alcohol consumption reduces but pain rises over the life course. Thus, we hypothesized that developmental variability in the bidirectional association between alcohol consumption and pain would vary as a function of age. This hypothesis wa…
View article: Alcohol use in emerging adults associated with lower rich-club connectivity and greater connectome network disorganization
Alcohol use in emerging adults associated with lower rich-club connectivity and greater connectome network disorganization Open
View article: Persistent and distressing psychotic-like experiences using adolescent brain cognitive development℠ study data
Persistent and distressing psychotic-like experiences using adolescent brain cognitive development℠ study data Open
View article: Demographic and mental health assessments in the adolescent brain and cognitive development study: Updates and age-related trajectories
Demographic and mental health assessments in the adolescent brain and cognitive development study: Updates and age-related trajectories Open
View article: Special Issue: Demographic and Mental Health Assessments in the Adolescent Brain and Cognitive Development Study: Updates and Longitudinal Trajectories
Special Issue: Demographic and Mental Health Assessments in the Adolescent Brain and Cognitive Development Study: Updates and Longitudinal Trajectories Open
The Adolescent Brain Cognitive Development (ABCD) Study of 11,880 youth incorporates a comprehensive range of measures assessing predictors and outcomes related to mental health across childhood and adolescence in participating youth, as w…
View article: Meaningful associations in the adolescent brain cognitive development study
Meaningful associations in the adolescent brain cognitive development study Open
View article: Acute effect of alcohol on working memory updating
Acute effect of alcohol on working memory updating Open
Aims To examine the acute effects of alcohol on working memory (WM) updating, including potential variation across the ascending limb (AL) and descending limb (DL) of the blood alcohol concentration (BAC) time‐course. Design A two‐session …
View article: College students’ receptiveness to intervention approaches for alcohol and cannabis use.
College students’ receptiveness to intervention approaches for alcohol and cannabis use. Open
OBJECTIVE: Addressing high-risk alcohol and cannabis use represent major challenges to institutions of higher education. A range of evidence-based treatment approaches are available, but little is known concerning students’ receptiveness t…
View article: Rates of Incidental Findings in Brain Magnetic Resonance Imaging in Children
Rates of Incidental Findings in Brain Magnetic Resonance Imaging in Children Open
Incidental findings in brain MRI and findings with potential clinical significance are both common in the general pediatric population. By assessing IFs and concurrent developmental and health measures and following these findings over the…
View article: Correspondence Between Perceived Pubertal Development and Hormone Levels in 9-10 Year-Olds From the Adolescent Brain Cognitive Development Study
Correspondence Between Perceived Pubertal Development and Hormone Levels in 9-10 Year-Olds From the Adolescent Brain Cognitive Development Study Open
Aim To examine individual variability between perceived physical features and hormones of pubertal maturation in 9–10-year-old children as a function of sociodemographic characteristics. Methods Cross-sectional metrics of puberty were util…
View article: Coping motives and negative affect: An ecological study of the antecedents of alcohol craving and alcohol use.
Coping motives and negative affect: An ecological study of the antecedents of alcohol craving and alcohol use. Open
Coping motives and within-person fluctuations in NA interactively predict alcohol craving. NA promotes drinking indirectly via increased craving, particularly among coping-motivated drinkers. Alcohol craving may be a proximal and sensitive…
View article: How robust is the p-factor? Using multitrait-multimethod modeling to inform the meaning of general factors of psychopathology in youth.
How robust is the p-factor? Using multitrait-multimethod modeling to inform the meaning of general factors of psychopathology in youth. Open
View article: An Examination of Sustained Versus Transient Distressing Psychotic-Like Experiences Using Adolescent Brain Cognitive Development℠ Study Data
An Examination of Sustained Versus Transient Distressing Psychotic-Like Experiences Using Adolescent Brain Cognitive Development℠ Study Data Open
Objective A potential distinguishing factor between more benign and transient psychotic-like experiences (PLEs) versus PLEs that predict risk for psychiatric disorders is whether the PLEs are sustained and distressing (sustained dPLEs). Th…
View article: Incipient Alcohol Use in Childhood: Early Alcohol Sipping and its Relations with Psychopathology and Personality – Corrigendum
Incipient Alcohol Use in Childhood: Early Alcohol Sipping and its Relations with Psychopathology and Personality – Corrigendum Open
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View article: Individual symptoms or categorical diagnoses? An epidemiological examination of the association between alcohol use, personality disorders, and psychological symptoms.
Individual symptoms or categorical diagnoses? An epidemiological examination of the association between alcohol use, personality disorders, and psychological symptoms. Open
Given the high comorbidity among psychological disorders, and in particular, personality disorders (PDs) and alcohol use disorder, screening and intervention efforts may benefit from the inclusion of transdiagnostic symptoms. Extant sympto…
View article: The “Big Everything”: Integrating and investigating dimensional models of psychopathology, personality, personality pathology, and cognitive functioning.
The “Big Everything”: Integrating and investigating dimensional models of psychopathology, personality, personality pathology, and cognitive functioning. Open
Common factors are increasingly used to model the structure of psychopathology ("p"), personality (General Factor of Personality [GFP]), pathological personality (General Factor of Pathological Personality [GFPP]), and intelligence …