R. Sureshkumar
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View article: Acylcarnitine enrichment as a characteristic of rheumatoid arthritis fibroblast-like synoviocyte metabolic fingerprint
Acylcarnitine enrichment as a characteristic of rheumatoid arthritis fibroblast-like synoviocyte metabolic fingerprint Open
Acylcarnitine accumulation is a characteristic of RA FLS metabolic fingerprint and could be linked to mitochondrial dysfunction. In patients with early RA, acylcarnitine content in serum decreases after successful anti-rheumatic treatment.…
View article: SUCCESSFUL MANAGEMENT OF FALSE ANESTRUS IN A PUNGANUR COW BY DOUBLE PGF2α PROTOCOL
SUCCESSFUL MANAGEMENT OF FALSE ANESTRUS IN A PUNGANUR COW BY DOUBLE PGF2α PROTOCOL Open
A pluriparous Punganur cow calved 9 months back was presented to Large Animal Gynaecology Unit with the history of anestrus. On rectal examination, uterus was flaccid and uterine horns were similar. Transrectal ultrasonography revealed pre…
View article: POS0066 METABOLIC ALTERATIONS IN RHEUMATOID ARTHRITIS: INSIGHTS FROM METABOLOMICS ANALYSIS IN JOINT FIBROBLASTS AND SERUM
POS0066 METABOLIC ALTERATIONS IN RHEUMATOID ARTHRITIS: INSIGHTS FROM METABOLOMICS ANALYSIS IN JOINT FIBROBLASTS AND SERUM Open
View article: The combined impact of thymosin beta 4 and selenium on diabetic ulcers: a comprehensive review
The combined impact of thymosin beta 4 and selenium on diabetic ulcers: a comprehensive review Open
Thymosin β4 (Tβ4) is a peptide with significant therapeutic potential for enhancing wound healing and tissue regeneration, particularly in the context of diabetic ulcers. This review explores the combined effects of Tβ4 and selenium, empha…
View article: Management of post-queening unilateral uterine horn prolapse with involvement of the uterine body in a Persian queen cat
Management of post-queening unilateral uterine horn prolapse with involvement of the uterine body in a Persian queen cat Open
View article: Screening and diagnosis of diabetes meletus in pregnant, diestrus and pseudopregnant bitches
Screening and diagnosis of diabetes meletus in pregnant, diestrus and pseudopregnant bitches Open
View article: Acylcarnitine Enrichment as a Characteristic of Rheumatoid Arthritis Fibroblast-Like Synoviocyte Metabolic Fingerprint
Acylcarnitine Enrichment as a Characteristic of Rheumatoid Arthritis Fibroblast-Like Synoviocyte Metabolic Fingerprint Open
View article: Genetic variability, genotyping, and genomics of <i>Mycobacterium leprae</i>
Genetic variability, genotyping, and genomics of <i>Mycobacterium leprae</i> Open
Leprosy, caused by Mycobacterium leprae and Mycobacterium lepromatosis, remains a significant global health issue despite a tremendous decline in its worldwide prevalence in the last four decades. Mycobacterium leprae strains possess very …
View article: Diagnosis and surgical management of vaginal fibroid concurrent with ovariohysterectomy in a geriatric Siberian husky
Diagnosis and surgical management of vaginal fibroid concurrent with ovariohysterectomy in a geriatric Siberian husky Open
View article: MEDIAN EPISIOTOMY APPROACH IN A MINIATURE POMERANIAN WITH VULVAL HYPOPLASIA: A CASE REPORT
MEDIAN EPISIOTOMY APPROACH IN A MINIATURE POMERANIAN WITH VULVAL HYPOPLASIA: A CASE REPORT Open
This case report details the episiotomy approach employed in managing vulval hypoplasia in a two year old Miniature Pomeranian bitch. The animal was presented to the Teaching Veterinary Clinical Complex, Veterinary Gynaecology and Obstetri…
View article: Ultrasonographic evaluation of fetal echo biometry and serum progesterone changes in normal and aborted pregnancies in bitches
Ultrasonographic evaluation of fetal echo biometry and serum progesterone changes in normal and aborted pregnancies in bitches Open
Thirty bitches of different breeds, weighing 5 to 40 kg and aged between 2 to 6 years presented to the Small Animal Gynaecology unit of Madras Veterinary College, Chennai for pregnancy diagnosis (after 30-35 days of mating) and were divide…
View article: Unveiling a rare case: cyclopia and its radiographic features in a non-descript primiparous heifer
Unveiling a rare case: cyclopia and its radiographic features in a non-descript primiparous heifer Open
Cyclopia, an exceedingly rare congenital anomaly, presents intricate deformities affecting the skull, orbits, brain, and nasal cavity, often featuring a singular or partially divided eye within a solitary orbit. Despite medical advancement…
View article: BIOSURFACTANTS: SUSTAINABLE ALTERNATIVE TO SYNTHETIC SURFACTANTS AND THEIR APPLICATIONS
BIOSURFACTANTS: SUSTAINABLE ALTERNATIVE TO SYNTHETIC SURFACTANTS AND THEIR APPLICATIONS Open
Biosurfactants are surface active agents produced by microorganisms, which help reduce surface or interfacial tension between two immiscible liquids like oil and water. In recent years, Due to their environmentally friendly nature and wide…
View article: Arterial Thromboembolism in a Domestic Cat – A report
Arterial Thromboembolism in a Domestic Cat – A report Open
Arterial thromboembolism is more common in cats. Generally, it develops without premonitory signs. When the thrombus lodged in aortic trifurcation posterior paresis develops. This paper documents one such case and its successful management…
View article: Morphometric studies of follicular development in ovaries of prepubertal and adult bitches
Morphometric studies of follicular development in ovaries of prepubertal and adult bitches Open
View article: Successful management of dystocia due to fetal mummification combined with stillbirth in a beagle Bitch
Successful management of dystocia due to fetal mummification combined with stillbirth in a beagle Bitch Open
A two-year-old full-term pregnant beagle bitch was presented to Madras Veterinary College Teaching Hospital with a history of anorexia and straining with black vaginal discharge for more than 18 hours. Clinical examination revealed pyrexia…
View article: Matrix Metalloproteinase-2 (MMP-2): As an Essential Factor in Cancer Progression
Matrix Metalloproteinase-2 (MMP-2): As an Essential Factor in Cancer Progression Open
The development of cancer has been a multistep process involving mutation, proliferation, survival, invasion, and metastasis. Of all the characteristics of cancer, metastasis is believed to be the hallmark as it is responsible for the high…
View article: Genome sequencing of SARS-CoV-2 omicron variants in Delhi reveals alterations in immunogenic regions in spike glycoprotein
Genome sequencing of SARS-CoV-2 omicron variants in Delhi reveals alterations in immunogenic regions in spike glycoprotein Open
The SARS-CoV-2 omicron variants keep accumulating a large number of mutations in the spike (S) protein, which contributes to greater transmissibility and a rapid rise to dominance within populations. The identification of mutations and the…
View article: A Unique Case of Emphysematous Pyometra and Uterine Adenocarcinoma Co-Incidence in a Doberman Female Dog
A Unique Case of Emphysematous Pyometra and Uterine Adenocarcinoma Co-Incidence in a Doberman Female Dog Open
Background: Emphysematous pyometra is a rare and potentially life-threatening condition observed in intact female dogs, characterized by the accumulation of infectious exudate within the uterus and accompanied by the presence of gas. This …
View article: Hyperadrenocorticism in Dogs: Impact on Reproduction and Diagnostic Insights from Ultrasonography
Hyperadrenocorticism in Dogs: Impact on Reproduction and Diagnostic Insights from Ultrasonography Open
Canine Cushing's syndrome, also known as hyperadrenocorticism (HAC), is one of the most prevalent endocrinopathies observed in dogs, characterized by elevated cortisol levels. The majority of cases are associated with pituitary tumors, lea…
View article: Evaluation of lauric acid and L-glutamate individually and in combination as pro-nutrient growth promoters in broiler chickens
Evaluation of lauric acid and L-glutamate individually and in combination as pro-nutrient growth promoters in broiler chickens Open
This experimental study aimed to elucidate the effect of dietary supplementation of lauric acid and L-glutamic acid on the production performance and carcass characteristics of broilers. Day-old broiler chicks (160) were randomly divided i…
View article: Insights from establishing a high throughput viral diagnostic laboratory for SARS-CoV-2 RT-PCR testing facility: challenges and experiences
Insights from establishing a high throughput viral diagnostic laboratory for SARS-CoV-2 RT-PCR testing facility: challenges and experiences Open
Background : The World Health Organization declared the coronavirus disease 2019 (COVID-19) a global pandemic on 11 March 2020. Identifying the infected people and isolating them was the only measure that was available to control the viral…
View article: Perspective Chapter: Microemulsion as a Game Changer to Conquer Cancer with an Emphasis on Herbal Compounds
Perspective Chapter: Microemulsion as a Game Changer to Conquer Cancer with an Emphasis on Herbal Compounds Open
Microemulsions are lipid based drug delivery system consisting of oil, water, surfactant and often a co-surfactant. They are prepared in order to deliver the drug in an effective manner so as to obtain the desired therapeutic activity. Com…
View article: 5-Fluorouracil and Curcumin Combination Coated with Pectin and Its Strategy towards Titanium Dioxide, Dimethylhydrazine Colorectal Cancer Model with the Evaluation of the Blood Parameters
5-Fluorouracil and Curcumin Combination Coated with Pectin and Its Strategy towards Titanium Dioxide, Dimethylhydrazine Colorectal Cancer Model with the Evaluation of the Blood Parameters Open
Colorectal cancer is considered the third most common cancer and the second leading cause of death globally. It has been proven that titanium dioxide nanoparticles produce oxidative stress and can lead to chronic inflammation, which could …
View article: Neuroprotection by resveratrol: A review on brain delivery strategies for Alzheimer’s and Parkinson’s disease
Neuroprotection by resveratrol: A review on brain delivery strategies for Alzheimer’s and Parkinson’s disease Open
Development and Validation of a New Simple Liquid Chromatographic Method for Determination of Coumarin and its 7-Hydroxy Metabolite as a Marker of Cytochrome P450 2A6 in RatsSundeep Bath, Wael Ebied, Hytham Ahmed, Fawzy Elbarbry
View article: Multidrug Resistance of Cancer Cells and the Vital Role of P-Glycoprotein
Multidrug Resistance of Cancer Cells and the Vital Role of P-Glycoprotein Open
P-glycoprotein (P-gp) is a major factor in the multidrug resistance phenotype in cancer cells. P-gp is a protein that regulates the ATP-dependent efflux of a wide range of anticancer medicines and confers resistance. Due to its wide specif…
View article: A Regional Pooling Intervention in a High-Throughput COVID-19 Diagnostic Laboratory to Enhance Throughput, Save Resources and Time Over a Period of 6 Months
A Regional Pooling Intervention in a High-Throughput COVID-19 Diagnostic Laboratory to Enhance Throughput, Save Resources and Time Over a Period of 6 Months Open
An effective and rapid diagnosis has great importance in tackling the ongoing COVID-19 pandemic through isolation of the infected individuals to curb the transmission and initiation of specialized treatment for the disease. It has been pro…
View article: Multidrug Resistance in Cancer Cells: Focus on a Possible Strategy Plan to Address Colon Carcinoma Cells
Multidrug Resistance in Cancer Cells: Focus on a Possible Strategy Plan to Address Colon Carcinoma Cells Open
Even though various treatment methods are available for cancer, the death curve is not reducing. The diagnosis of cancer at the fourth stage and drug resistance are the leading reasons for treatment failure and lower survival rates. In thi…
View article: Preformulation Studies Of S-Equol
Preformulation Studies Of S-Equol Open
in S-Equol is an intestinal bacterial metabolite of the soybean isoflavone daidzein which has potent Antioxidant, and Anti-inflammatory properties in humans.Evaluation of solubility, Molecular weight, Melting point, Compatibility, and Stab…
View article: 5-Fluorouracil And Curcumin With Pectin Coating As a Treatment Regimen For Titanium Dioxide Induced Colon Cancer Model
5-Fluorouracil And Curcumin With Pectin Coating As a Treatment Regimen For Titanium Dioxide Induced Colon Cancer Model Open
Objective: Induction of colorectal cancer in Wister rats using titanium dioxide and dimethylhydrazine and treatment using the physical conjugate of 5-Fluorouracil and Curcumin, with a synergistic approach. Methods : Compatibility studies a…