R. Suzanne Beard
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View article: Differentiated community-based point-of-care early infant diagnosis to improve HIV diagnosis and ART initiation among infants and young children in Zambia: a quasi-experimental cohort study
Differentiated community-based point-of-care early infant diagnosis to improve HIV diagnosis and ART initiation among infants and young children in Zambia: a quasi-experimental cohort study Open
Introduction An estimated 800 000 children (<15 years) globally living with HIV remain undiagnosed. To reach these children with timely HIV testing services during infancy, we implemented a community-based differentiated care model using m…
View article: Molecular epidemiology of rubella during the pre- and post-elimination eras in the Americas
Molecular epidemiology of rubella during the pre- and post-elimination eras in the Americas Open
Since the last case of indigenous rubella virus (RuV) was detected in 2009 in the Region of the Americas, sporadic rubella and congenital rubella cases have been confirmed, and subsequently, a low number of associated sequences have been r…
View article: The impact of adherence counseling incorporating a point of care urine tenofovir assay on virologic suppression among individuals failing tenofovir-lamivudine-dolutegravir: A pre-post intervention study
The impact of adherence counseling incorporating a point of care urine tenofovir assay on virologic suppression among individuals failing tenofovir-lamivudine-dolutegravir: A pre-post intervention study Open
View article: Pediatric Rash Illness Outbreak with Initial Positive Measles Immunoglobulin M Antibody Test Results — American Samoa, March–July 2023
Pediatric Rash Illness Outbreak with Initial Positive Measles Immunoglobulin M Antibody Test Results — American Samoa, March–July 2023 Open
On April 24, 2023, the American Samoa Department of Health (ASDoH) declared a public health emergency amid concern about a possible measles outbreak given low 2-dose vaccination coverage at the time. ASDoH had received two positive measles…
View article: The Global Measles and Rubella Laboratory Network Supports High-Quality Surveillance
The Global Measles and Rubella Laboratory Network Supports High-Quality Surveillance Open
With 762 laboratories, the Global Measles and Rubella Laboratory Network (GMRLN) is the largest laboratory network coordinated by the World Health Organization (WHO). Like the Global Polio Laboratory Network, the GMRLN has multiple tiers, …
View article: Building Quality Control for Molecular Assays in the Global Measles and Rubella Laboratory Network
Building Quality Control for Molecular Assays in the Global Measles and Rubella Laboratory Network Open
More than 100 laboratories in the World Health Organization Global Measles and Rubella Laboratory Network (GMRLN) perform nucleic acid-based methods for case confirmation of measles or rubella infections and/or strain surveillance (genotyp…
View article: Measles and Rubella Diagnostic and Classification Challenges in Near- and Post-Elimination Countries
Measles and Rubella Diagnostic and Classification Challenges in Near- and Post-Elimination Countries Open
Measles and rubella are vaccine-preventable viral diseases and can be prevented by safe, highly effective vaccination with measles- and rubella-containing vaccines. Given the myriad causes of febrile exanthems, laboratory surveillance for …
View article: Neutralization of Rubella Vaccine Virus and Immunodeficiency-Related Vaccine-Derived Rubella Viruses by Intravenous Immunoglobulins
Neutralization of Rubella Vaccine Virus and Immunodeficiency-Related Vaccine-Derived Rubella Viruses by Intravenous Immunoglobulins Open
The association between granulomas and vaccine-derived rubella virus (VDRV) in people with primary immunodeficiencies has raised concerns about the ability of immunoglobulin preparations to neutralize VDRVs. We investigated the capacity of…
View article: The Impact of Adherence Counselling Incorporating a Point of Care Urine Tenofovir Assay on Virologic Suppression Among Individuals Failing Tenofovir-Lamivudine-Dolutegravira Pre - Post Intervention Study
The Impact of Adherence Counselling Incorporating a Point of Care Urine Tenofovir Assay on Virologic Suppression Among Individuals Failing Tenofovir-Lamivudine-Dolutegravira Pre - Post Intervention Study Open
View article: Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018
Progress in scale up of HIV viral load testing in select sub-Saharan African countries 2016–2018 Open
Introduction We assessed progress in HIV viral load (VL) scale up across seven sub-Saharan African (SSA) countries and discussed challenges and strategies for improving VL coverage among patients on anti-retroviral therapy (ART). Methods A…
View article: Contribution of PEPFAR-Supported HIV and TB Molecular Diagnostic Networks to COVID-19 Testing Preparedness in 16 Countries
Contribution of PEPFAR-Supported HIV and TB Molecular Diagnostic Networks to COVID-19 Testing Preparedness in 16 Countries Open
The US President's Emergency Plan for AIDS Relief (PEPFAR) supports molecular HIV and tuberculosis diagnostic networks and information management systems in low- and middle-income countries. We describe how national programs leveraged thes…
View article: “Testing Can Be Done Anywhere”: A Qualitative Assessment of Targeted Community-Based Point-of-Care Early Infant Diagnosis of HIV in Lusaka, Zambia
“Testing Can Be Done Anywhere”: A Qualitative Assessment of Targeted Community-Based Point-of-Care Early Infant Diagnosis of HIV in Lusaka, Zambia Open
We demonstrate the acceptability, appropriateness, and feasibility of implementing the community POC model in Zambia, while identifying potential challenges related to client privacy and platform field operations. The community POC model m…
View article: Correction to: A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks
Correction to: A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks Open
View article: Persistence of Positive RT-PCR Results for Over 70 Days in Two Travelers with COVID-19
Persistence of Positive RT-PCR Results for Over 70 Days in Two Travelers with COVID-19 Open
The relation of continuing to test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcription real-time polymerase chain reaction (RT-PCR) to infectivity remains unclear, with numerous consequences. …
View article: Identifying current and emerging resources and tools utilized for detection, prediction, and visualization of viral zoonotic disease clusters: a Delphi study
Identifying current and emerging resources and tools utilized for detection, prediction, and visualization of viral zoonotic disease clusters: a Delphi study Open
Zoonotic disease surveillance presents a substantial problem in the management of public health. Globally, zoonoses have the potential to spread and negatively impact population health economic growth, and security. This research was condu…
View article: High Levels of HIV-1 Drug Resistance in Children Who Acquired HIV Infection Through Mother to Child Transmission in the Era of Option B+, Haiti, 2013 to 2014
High Levels of HIV-1 Drug Resistance in Children Who Acquired HIV Infection Through Mother to Child Transmission in the Era of Option B+, Haiti, 2013 to 2014 Open
Background: The main objective of this study was to determine the frequency and patterns of HIV drug resistance–associated mutations among children under 18 months of age born to HIV-1–positive mothers enrolled in the prevention of mother-…
View article: A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks
A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks Open
Background Zoonotic diseases account for a substantial portion of infectious disease outbreaks and burden on public health programs to maintain surveillance and preventative measures. Taking advantage of new modeling approaches and data so…
View article: Utilization of dried blood spot specimens can expedite nationwide surveillance of HIV drug resistance in resource-limited settings
Utilization of dried blood spot specimens can expedite nationwide surveillance of HIV drug resistance in resource-limited settings Open
The study demonstrates a favorable outcome of using DBS for nationwide surveillance of HIVDR in ART patients. Our results confirm that DBS collected and stored at ambient temperature for two weeks, and shipped with routine courier services…
View article: MOESM1 of A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks
MOESM1 of A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks Open
Additional file 1. Full text screening summary: Full text articles reviewed for inclusion and exclusion criteria.
View article: MOESM3 of A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks
MOESM3 of A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks Open
Additional file 3. TIDieR assessment: Articles assessed using the TIDieR tool.
View article: MOESM2 of A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks
MOESM2 of A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks Open
Additional file 2. MMAT assessment: Articles assessed using the MMAT tool.
View article: MOESM4 of A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks
MOESM4 of A systematic review of spatial decision support systems in public health informatics supporting the identification of high risk areas for zoonotic disease outbreaks Open
Additional file 4. SDSS summarization: Characteristics of final SDSS selection.
View article: Combatting Global Infectious Diseases: A Network Effect of Specimen Referral Systems
Combatting Global Infectious Diseases: A Network Effect of Specimen Referral Systems Open
The recent Ebola virus outbreak in West Africa clearly demonstrated the critical role of laboratory systems and networks in responding to epidemics. Because of the huge challenges in establishing functional laboratories at all tiers of hea…
View article: Early Diagnosis of HIV Infection in Infants — One Caribbean and Six Sub-Saharan African Countries, 2011–2015
Early Diagnosis of HIV Infection in Infants — One Caribbean and Six Sub-Saharan African Countries, 2011–2015 Open
Pediatric human immunodeficiency virus (HIV) infection remains an important public health issue in resource-limited settings. In 2015, 1.4 million children aged 50% decline. The most common challenges for access to testing for early infant…
View article: A Proposed Framework for the Implementation of Early Infant Diagnosis Point-of-Care
A Proposed Framework for the Implementation of Early Infant Diagnosis Point-of-Care Open
Early diagnosis of HIV infection in infants and children remains a challenge in resource-limited settings, with approximately half of all HIV-exposed infants receiving virological testing for HIV by the recommended age of 2 months in 2015.…
View article: A high-precision rule-based extraction system for expanding geospatial metadata in GenBank records
A high-precision rule-based extraction system for expanding geospatial metadata in GenBank records Open
Objective The metadata reflecting the location of the infected host (LOIH) of virus sequences in GenBank often lacks specificity. This work seeks to enhance this metadata by extracting more specific geographic information from related full…
View article: Knowledge-driven geospatial location resolution for phylogeographic models of virus migration
Knowledge-driven geospatial location resolution for phylogeographic models of virus migration Open
Summary: Diseases caused by zoonotic viruses (viruses transmittable between humans and animals) are a major threat to public health throughout the world. By studying virus migration and mutation patterns, the field of phylogeography provid…
View article: Analyses of Merging Clinical and Viral Genetic Data for Influenza Surveillance.
Analyses of Merging Clinical and Viral Genetic Data for Influenza Surveillance. Open
The annual influenza vaccine is one of the most common public health interventions and is universally recommended for all individuals older than six months. Vaccine composition depends on viruses circulating over the past flu season and ar…