Tom Sutherland
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View article: Crohn’s Disease Stricture Response to Treatment Assessed with Magnetic Resonance Imaging and Intestinal Ultrasound: STRIDENT Randomized Trial
Crohn’s Disease Stricture Response to Treatment Assessed with Magnetic Resonance Imaging and Intestinal Ultrasound: STRIDENT Randomized Trial Open
Background Transmural healing is emerging as a key treatment target in Crohn’s disease. This study aimed to determine the role of magnetic resonance imaging (MRI) and intestinal ultrasound (IUS) in the assessment of the radiologic response…
View article: A new protocolized treatment strategy optimizing medical and surgical care leads to improved healing of Crohn’s perianal fistulas
A new protocolized treatment strategy optimizing medical and surgical care leads to improved healing of Crohn’s perianal fistulas Open
Background and Aims Crohn’s perianal fistula healing rates remain low. We evaluated the efficacy of a protocolized multidisciplinary treatment strategy optimizing care in adults with Crohn’s perianal fistulas. Methods A new treatment strat…
View article: P0260 Scoring indices grading radiologic disease activity severity on magnetic resonance imaging strongly reflect clinical healing of Crohn’s perianal fistulas
P0260 Scoring indices grading radiologic disease activity severity on magnetic resonance imaging strongly reflect clinical healing of Crohn’s perianal fistulas Open
Background Magnetic resonance imaging (MRI) is the gold-standard for evaluating Crohn’s perianal fistulas. Multiple scoring indices to grade radiologic disease activity severity have been established, with limited comparative data and a la…
View article: Evaluation of Task Specific Productivity Improvements Using a Generative Artificial Intelligence Personal Assistant Tool
Evaluation of Task Specific Productivity Improvements Using a Generative Artificial Intelligence Personal Assistant Tool Open
This study evaluates the productivity improvements achieved using a generative artificial intelligence personal assistant tool (PAT) developed by Trane Technologies. The PAT, based on OpenAI’s GPT 3.5 model, was deployed on Microsoft Azure…
View article: Evaluation of Task Specific Productivity Improvements Using a Generative Artificial Intelligence Personal Assistant Tool
Evaluation of Task Specific Productivity Improvements Using a Generative Artificial Intelligence Personal Assistant Tool Open
This study evaluates the productivity improvements achieved using a generative artificial intelligence personal assistant tool (PAT) developed by Trane Technologies. The PAT, based on OpenAI's GPT 3.5 model, was deployed on Microsoft Azure…
View article: Improving Hepatocellular Carcinoma Surveillance Outcomes in Patients with Cirrhosis after Hepatitis C Cure: A Modelling Study
Improving Hepatocellular Carcinoma Surveillance Outcomes in Patients with Cirrhosis after Hepatitis C Cure: A Modelling Study Open
Background & Aims: Hepatocellular carcinoma (HCC) presents a significant global health challenge, particularly among individuals with liver cirrhosis, with hepatitis C (HCV) a major cause. In people with HCV-related cirrhosis, an increased…
View article: Micro-enema prior to prostate MRI reduces rectal gas and gas-related artefacts improving image quality
Micro-enema prior to prostate MRI reduces rectal gas and gas-related artefacts improving image quality Open
Purpose There are conflicting results in the literature regarding bowel preparation prior to prostate Magnetic Resonance Imaging (MRI) and its effect on image quality. Our aim was to determine whether the administration of a micro-enema im…
View article: Effect of laparoscopic sleeve gastrectomy versus laparoscopic Roux‐en‐Y gastric bypass on body composition
Effect of laparoscopic sleeve gastrectomy versus laparoscopic Roux‐en‐Y gastric bypass on body composition Open
Background There is limited data with respect to body composition changes for laparoscopic sleeve gastrectomy (SG) and laparoscopic Roux‐en‐Y gastric bypass (RYGB). The objective of this study was to analyse changes in body composition bet…
View article: Fluorine-18–labelled Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography or Magnetic Resonance Imaging to Diagnose and Localise Prostate Cancer. A Prospective Single-arm Paired Comparison (PEDAL)
Fluorine-18–labelled Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography or Magnetic Resonance Imaging to Diagnose and Localise Prostate Cancer. A Prospective Single-arm Paired Comparison (PEDAL) Open
In this trial, we compared the ability of 18F-labelled prostate-specific membrane antigen positron emission tomography/computed tomography (PSMA-PET/CT) with that of multiparametric magnetic resonance imaging (mpMRI) to diagnose prostate c…
View article: P644 Body composition does not predict clinical course in patients with acute severe ulcerative colitis
P644 Body composition does not predict clinical course in patients with acute severe ulcerative colitis Open
Background Acute Severe Ulcerative Colitis (ASUC) is a life-threatening complication of UC. Previous research has shown that body composition parameters, including sarcopaenia, are associated with outcomes in IBD. However, the relationship…
View article: P547 Improved clinical and radiologic healing of Crohn’s perianal fistulas using a novel coordinated care model optimising medical and surgical treatments: A prospective real-world observational study
P547 Improved clinical and radiologic healing of Crohn’s perianal fistulas using a novel coordinated care model optimising medical and surgical treatments: A prospective real-world observational study Open
Background Despite best standard care, sustained healing rates of Crohn’s perianal fistulas remain low. A novel coordinated multi-disciplinary care model optimising medical and surgical treatment was established with the aim to improve fis…
View article: Reproducibility and Accuracy of the PRIMARY Score on PSMA PET and of PI-RADS on Multiparametric MRI for Prostate Cancer Diagnosis Within a Real-World Database
Reproducibility and Accuracy of the PRIMARY Score on PSMA PET and of PI-RADS on Multiparametric MRI for Prostate Cancer Diagnosis Within a Real-World Database Open
The PRIMARY score is a 5-category scale developed to identify clinically significant intraprostate malignancy (csPCa) on 68Ga-prostate-specific membrane antigen (PSMA)-11 PET/CT (68Ga-PSMA PET) using a combination of anatomic site, pattern…
View article: P669 Improving Crohn’s disease stricture dilation outcome: Effect of repeated dilation, needle knife stricturotomy, and ongoing active inflammation
P669 Improving Crohn’s disease stricture dilation outcome: Effect of repeated dilation, needle knife stricturotomy, and ongoing active inflammation Open
Background Traditionally Crohn’s disease strictures have been treated by a single endoscopic balloon dilation (EBD), repeated only for obstructive symptom recurrence. We postulated that scheduled repeated EBD may result in greater dilation…
View article: P749 Crohn’s disease stricture response and resolution with adalimumab therapy demonstrated with intestinal ultrasound. The STRIDENT randomised trial
P749 Crohn’s disease stricture response and resolution with adalimumab therapy demonstrated with intestinal ultrasound. The STRIDENT randomised trial Open
Background Transmural healing is a treatment goal in the management of Crohn’s disease, and intestinal ultrasound (IUS) is potentially a sensitive, non-invasive and reproducible means to assess the response to treatment. Methods The STRIDE…
View article: PEDAL protocol: a prospective single-arm paired comparison of multiparametric MRI and 18F-DCPFyl PSMA PET/CT to diagnose prostate cancer
PEDAL protocol: a prospective single-arm paired comparison of multiparametric MRI and 18F-DCPFyl PSMA PET/CT to diagnose prostate cancer Open
Introduction Prostate-specific membrane antigen positron emission tomography (PSMA-PET) has emerged as valuable imaging to assessing metastatic disease in prostate malignancy. However, there has been limited studies exploring the utility P…
View article: Targeted Renal Biopsy: Predictors on Imaging
Targeted Renal Biopsy: Predictors on Imaging Open
Objectives The renal nephrometry score uses imaging characteristics such as lesion diameter, location, and proximity to hilar vessels to categorize renal masses by complexity for preoperative planning. These characteristics may also be use…
View article: <scp> Pathological predictors of <sup>18</sup> F‐DCFPyL prostate‐specific membrane antigen </scp> ‐ <scp>positive recurrence after radical prostatectomy</scp>
<span> Pathological predictors of <sup>18</sup> F‐DCFPyL prostate‐specific membrane antigen </span> ‐ <span>positive recurrence after radical prostatectomy</span> Open
Objectives To assess the correlation of pathological radical prostatectomy (RP) specimen features and prostate‐specific antigen (PSA) characteristics to imaging findings on subsequent 18 F‐DCFPyL positron emission tomography/computed tomog…
View article: Combination of <scp>MRI</scp> prostate and <scp>18F‐DCFPyl PSMA PET</scp>/<scp>CT</scp> detects all clinically significant prostate cancers in treatment‐naive patients: An international multicentre retrospective study
Combination of <span>MRI</span> prostate and <span>18F‐DCFPyl PSMA PET</span>/<span>CT</span> detects all clinically significant prostate cancers in treatment‐naive patients: An international multicentre retrospective study Open
Introduction Clinical and biochemical assessment and biopsies can miss clinically significant prostate cancers (csPCa) in up to 20% of patients and diagnose clinically insignificant tumours leading to overtreatment. This retrospective stud…
View article: Changes in Management After <sup>18</sup>F-DCFPyL PSMA PET in Patients Undergoing Postprostatectomy Radiotherapy, with Early Biochemical Response Outcomes
Changes in Management After <sup>18</sup>F-DCFPyL PSMA PET in Patients Undergoing Postprostatectomy Radiotherapy, with Early Biochemical Response Outcomes Open
Prostate-specific membrane antigen (PSMA) tracers have increased sensitivity in the detection of prostate cancer, compared with conventional imaging. We assessed the management impact of 18F-DCFPyL PSMA PET/CT in patients with prostate-spe…
View article: O-B05 Does rapid or gradual weight loss following bariatric surgery affect lean body mass depreciation?
O-B05 Does rapid or gradual weight loss following bariatric surgery affect lean body mass depreciation? Open
Background Controversy exists regarding the influence of the rate of weight loss on long-term body composition. The objective of this study was to compare body composition changes in patients with successful and unsuccessful weight loss 12…
View article: Non-Prostate Cancer Tumours: Incidence on 18f-Dcfpyl Psma Pet/Ct and Psma Expression Characteristics in 1445 Patients.
Non-Prostate Cancer Tumours: Incidence on 18f-Dcfpyl Psma Pet/Ct and Psma Expression Characteristics in 1445 Patients. Open
Purpose Prostate cancer (PCa) imaging has been revolutionized by Positron emission tomography (PET) tracers targeted to prostate specific membrane antigen (PSMA). Identification and characterization of non-PCa tumors has become an increasi…
View article: The inferior vena cava: anatomical variants and acquired pathologies
The inferior vena cava: anatomical variants and acquired pathologies Open
The inferior vena cava (IVC) is the largest vein in the body, draining blood from the abdomen, pelvis and lower extremities. This pictorial review summarises normal anatomy and embryological development of the IVC. In addition, we highligh…
View article: Prospective randomised controlled trial of adults with perianal fistulising Crohn’s disease and optimised therapeutic infliximab levels: PROACTIVE trial study protocol
Prospective randomised controlled trial of adults with perianal fistulising Crohn’s disease and optimised therapeutic infliximab levels: PROACTIVE trial study protocol Open
Introduction Perianal fistulising Crohn’s disease (pfCD) can be somewhat treatment refractory. Higher infliximab trough levels (TLIs) may improve fistula healing rates; however, it remains unclear whether escalating infliximab therapy to m…