Ryo Takagi
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View article: Evaluating Suitability for High-frequency Train Operations of Track Layout at a Double-track Railway Terminus
Evaluating Suitability for High-frequency Train Operations of Track Layout at a Double-track Railway Terminus Open
View article: Continuous adipose-derived stem cell therapy from the neonatal stage effectively reduces Duchenne muscular dystrophy symptoms in rats
Continuous adipose-derived stem cell therapy from the neonatal stage effectively reduces Duchenne muscular dystrophy symptoms in rats Open
Background The optimal timing for mesenchymal stem cell (MSC) therapy in Duchenne muscular dystrophy (DMD) remains unclear. Methods Neonatal DMD rats received intraperitoneal adipose-derived MSCs according to three schedules: early (postna…
View article: Mid-term outcomes of a bio-artificial pleura composed of autologous dermal fibroblasts used to close intraoperative pulmonary air leaks caused by intraoperative pleural injury: A case report
Mid-term outcomes of a bio-artificial pleura composed of autologous dermal fibroblasts used to close intraoperative pulmonary air leaks caused by intraoperative pleural injury: A case report Open
This report of two cases demonstrated the mid-term safety of bio-artificial pleural transplantation using cultured autologous DFS for pleural injury.
View article: Correction: Unusual nodular goiter with recurrent laryngeal nerve palsy due to severe degeneration caused by intense chronic inflammation: a case report with histopathological evidence and review of the literature
Correction: Unusual nodular goiter with recurrent laryngeal nerve palsy due to severe degeneration caused by intense chronic inflammation: a case report with histopathological evidence and review of the literature Open
View article: Intravenous mesenchymal stem cell transplantation mitigates pulmonary vascular remodeling but poses dose related risks in a pulmonary veno-occlusive disease model
Intravenous mesenchymal stem cell transplantation mitigates pulmonary vascular remodeling but poses dose related risks in a pulmonary veno-occlusive disease model Open
View article: Unusual nodular goiter with recurrent laryngeal nerve palsy due to severe degeneration caused by intense chronic inflammation: a case report with histopathological evidence and review of the literature
Unusual nodular goiter with recurrent laryngeal nerve palsy due to severe degeneration caused by intense chronic inflammation: a case report with histopathological evidence and review of the literature Open
Our literature review suggests that RLN palsy associated with thyroid mass lesions should not be considered a definitive indicator of malignancy because it can also be observed in BTD, although it is significantly less frequent than in mal…
View article: Establishment of reproducible method for production of cultured epidermal sheets with controlled melanocyte density
Establishment of reproducible method for production of cultured epidermal sheets with controlled melanocyte density Open
View article: Pictorial Review of MRI Findings of Glycogen Storage Disease from Children to Young Adults
Pictorial Review of MRI Findings of Glycogen Storage Disease from Children to Young Adults Open
Glycogen storage diseases (GSDs) are rare, inherited disorders of glycogen metabolism caused by a deficiency of enzymes or transporters. GSDs involve the liver, kidneys, skeletal muscles, and heart of children and young adults. The complic…
View article: Predictors of Severe Coughing and Its Impact on Bronchoalveolar Lavage and Transbronchial Lung Biopsy in Patients with Diffuse Lung Disease: Evaluation of Bronchoscopy Safety
Predictors of Severe Coughing and Its Impact on Bronchoalveolar Lavage and Transbronchial Lung Biopsy in Patients with Diffuse Lung Disease: Evaluation of Bronchoscopy Safety Open
Background/Objectives: Bronchoscopy is an invasive procedure, and patient coughing during the examination has been reported to cause significant distress. This study aimed to identify predictors of coughing severity and assess its impact o…
View article: Pictorial Review of MRI Findings of Glycogen Storage Disease from Children to Young Adults
Pictorial Review of MRI Findings of Glycogen Storage Disease from Children to Young Adults Open
Glycogen storage diseases (GSDs) are rare, inherited disorders of glycogen metabolism caused by a deficiency of enzymes or transporters. GSDs involve the liver, kidneys, skeletal muscles, and heart of children and young adults. The complic…
View article: Allogeneic fibroblast sheets prevent pulmonary air leaks caused by rat pleural defects without adhesion to the thoracic wall
Allogeneic fibroblast sheets prevent pulmonary air leaks caused by rat pleural defects without adhesion to the thoracic wall Open
View article: A Case of Myringoplasty Using Retympa<sup>®</sup> After Cochlear Implantation
A Case of Myringoplasty Using Retympa<sup>®</sup> After Cochlear Implantation Open
View article: Reply to Accurate Risk Prediction Model for Surgical Site Infection After Lower Third Molar Surgery
Reply to Accurate Risk Prediction Model for Surgical Site Infection After Lower Third Molar Surgery Open
View article: Clinical Evaluation of Acute Exacerbation of Interstitial Lung Disease in a Single Tertiary Center: Perspectives before and after the Coronavirus Disease 2019 Pandemic
Clinical Evaluation of Acute Exacerbation of Interstitial Lung Disease in a Single Tertiary Center: Perspectives before and after the Coronavirus Disease 2019 Pandemic Open
Background/Objectives: Acute exacerbation (AE) of interstitial lung disease (ILD) is a major challenge. This study aimed to retrospectively investigate occurrences of AEs in patients with ILDs, including idiopathic pulmonary fibrosis (IPF)…
View article: A multicenter, prospective, phase <scp>II</scp> trial of second‐line aflibercept plus <scp>FOLFIRI</scp> in patients with metastatic colorectal cancer refractory to an anti‐<scp>EGFR</scp> antibody: <scp>HGCSG1801</scp>
A multicenter, prospective, phase <span>II</span> trial of second‐line aflibercept plus <span>FOLFIRI</span> in patients with metastatic colorectal cancer refractory to an anti‐<span>EGFR</span> antibody: <span>HGCSG1801</span> Open
Aflibercept (AFL) plus FOLFIRI prolongs overall survival (OS) in patients with metastatic colorectal cancer (mCRC). However, there is limited evidence on the efficacy and safety of AFL plus FOLFIRI previously treated with anti‐epidermal gr…
View article: COVID-19 control protocol for rhinologic surgery
COVID-19 control protocol for rhinologic surgery Open
In January 2020, 14 medical staff members engaged in endona- sal endoscopic pituitary surgery at a hospital in Wuhan, China, were infected with a novel infection, coronavirus disease 2019 (COVID-19) (1). Since the nasal mucosa is a potenti…
View article: Dual-color FISH analyses of xenogeneic human fibroblast sheets transplanted to repair lung pleural defects in an immunocompromised rat model
Dual-color FISH analyses of xenogeneic human fibroblast sheets transplanted to repair lung pleural defects in an immunocompromised rat model Open
Background Pulmonary air leaks (PALs) due to visceral pleura injury during surgery is frequently observed after pulmonary resections and the complication is difficult to avoid in thoracic surgery. The development of postoperative PALs is t…
View article: A giant peripheral ossifying fibroma of the maxilla with extreme difficulty in clinical differentiation from malignancy: a case report and review of the literature
A giant peripheral ossifying fibroma of the maxilla with extreme difficulty in clinical differentiation from malignancy: a case report and review of the literature Open
Background Peripheral ossifying fibroma is a nonneoplastic inflammatory hyperplasia that originates in the periodontal ligament or periosteum in response to chronic mechanical irritation. Peripheral ossifying fibroma develops more commonly…
View article: Lessons learned from contamination with endotoxin originated from the supplement in the cell culture medium
Lessons learned from contamination with endotoxin originated from the supplement in the cell culture medium Open
View article: Effect of basic fibroblast growth factor with collagen/gelatin fixture in a rabbit model of nasal septum perforation
Effect of basic fibroblast growth factor with collagen/gelatin fixture in a rabbit model of nasal septum perforation Open
View article: Impact of Cough Severity on the Diagnostic Yield of Endobronchial Ultrasonography Transbronchial Biopsy with Guide Sheath: A Retrospective Observational Study
Impact of Cough Severity on the Diagnostic Yield of Endobronchial Ultrasonography Transbronchial Biopsy with Guide Sheath: A Retrospective Observational Study Open
Bronchoscopy is an invasive procedure, and patient coughing during examination has been reported to cause patient distress. This study aimed to clarify the relationship between cough severity and diagnostic yield of endobronchial ultrasono…
View article: Load-Separated Three-Dimensional Drive Link Control Applying Electric Motorcycle
Load-Separated Three-Dimensional Drive Link Control Applying Electric Motorcycle Open
View article: A validation study for wide-range remote assessment of cognitive functions in the healthy older Japanese population: a pilot randomised crossover trial
A validation study for wide-range remote assessment of cognitive functions in the healthy older Japanese population: a pilot randomised crossover trial Open
Background The assessment of a wide range of cognitive functions using video teleconference (VTC) systems cannot be applied in practice yet. We aimed to determine the feasibility and reliability of previously unvalidated remote cognitive f…
View article: Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3
Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3 Open
Background Melanocytes are an essential part of the epidermis, and their regeneration has received much attention because propagation of human adult melanocytes in vitro is too slow for clinical use. Differentiation from human pluripotent …
View article: Updated report of COVID-19 vaccine safety monitoring in Japan: booster doses for Omicron variants and vaccinations for infants and young children
Updated report of COVID-19 vaccine safety monitoring in Japan: booster doses for Omicron variants and vaccinations for infants and young children Open
View article: Evaluation of safety and efficacy of autologous oral mucosa-derived epithelial cell sheet transplantation for prevention of anastomotic restenosis in congenital esophageal atresia and congenital esophageal stenosis
Evaluation of safety and efficacy of autologous oral mucosa-derived epithelial cell sheet transplantation for prevention of anastomotic restenosis in congenital esophageal atresia and congenital esophageal stenosis Open
View article: Supplementary Figures 1 - 4 from Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer
Supplementary Figures 1 - 4 from Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer Open
Supplementary Figure S1 Receiver operating characteristic curve analysis of the respective marker genes. Supplementary Figure S2 Ages of CRC patients (upper) and non-CRC individuals (lower) with the indicated M-scores. Each dot represents …
View article: Data from Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer
Data from Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer Open
Aberrant DNA methylation could potentially serve as a biomarker for colorectal neoplasms. In this study, we assessed the feasibility of using DNA methylation detected in bowel lavage fluid (BLF) for colorectal cancer screening. A total of …
View article: Supplementary Figures 1 - 4 from Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer
Supplementary Figures 1 - 4 from Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer Open
Supplementary Figure S1 Receiver operating characteristic curve analysis of the respective marker genes. Supplementary Figure S2 Ages of CRC patients (upper) and non-CRC individuals (lower) with the indicated M-scores. Each dot represents …
View article: Supplementary Table 2 from Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer
Supplementary Table 2 from Analysis of DNA Methylation in Bowel Lavage Fluid for Detection of Colorectal Cancer Open
Results of ROC curve analysis for detection of CRC using BLF methylation