Explanipedia

Acute Impact of Lung Transplantation on Respiratory-Swallow Coordination, Swallowing Impairment, and Airway Invasion: A Prospective Cohort Study Open

Kahla Graham, Jungwha Lee, Rade Tomic, Ambalavanan Arunachalam, Bonnie Martin‐Harris · 2025

Performance of the FORD Versus Other Available Models for the Noninvasive Prediction of Pulmonary Hypertension in Patients with Interstitial Lung Disease Open

Ho Cheol Kim, Abhimanyu Chandel, Christopher S. King, Min Jee Kim, Malek Shawabkeh , et al. · 2025

The FORD model can be used to predict group 3 PH in both IPF patients and non-IPF ILD patients. It could serve as a tool for ILD patient selection for right heart catheterization as well as an enrichment tool for clinical trials targeting …

<i>In silico</i>perturbations provide multivariate interpretability in predicting post-lung transplant outcomes Open

Lucy Luo, Marcin Możejko, Nikolay S. Markov, Alec Peltekian, Sajjad Mohsin , et al. · 2024

Lung transplantation is a life-saving therapy for end-stage lung disease but has the poorest survival among solid organ transplants. We analyzed standardized electronic health record (EHR) data from the United Network for Organ Sharing (UN…

Respiratory‐swallow patterning and oropharyngeal swallowing impairment in patients undergoing evaluation for lung transplant Open

Kahla Graham, Erin L. Reedy, Jungwha Julia Lee, Elizabeth S. Norton, Ambalavanan Arunachalam , et al. · 2024

Background Although swallowing impairment is prevalent following lung transplantation, baseline respiratory and swallowing characteristics are often overlooked. Respiratory disease processes may predispose lung transplant candidates to alt…

Impact of bridging veno-venous extracorporeal membrane oxygenation to COVID-19 lung transplantation Open

Takahide Toyoda, Benjamin Louis Thomae, Taisuke Kaiho, Emily Cerier, Rade Tomic , et al. · 2024

Our findings suggest that VV-ECMO can be used to safely bridge patients with COVID-19 associated ARDS with right heart failure.

255TiP [DREAM] Double lung transplant registry aimed for lung-limited malignancies: A prospective registry study for medically refractory cancers Open

L.I-Y. Chung, Young Kwang Chae, Rade Tomic, A. Bharat · 2024

Adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA) are listed as 'special circumstances' for lung transplantation according to a consensus document from the International Society for Heart and Lung Transplantation (IS…

COVID-19 in hospitalized lung and non-lung solid organ transplant recipients: A comparative analysis from a multicenter study Open

Heldman M.R., Kates O.S., Kassem Safa, Kotton C.N., Georgia S.J. , et al. · 2024

Lung transplant recipients (LTR) with coronavirus disease 2019 (COVID-19) may have higher mortality than non-lung solid organ transplant recipients (SOTR), but direct comparisons are limited. Risk factors for mortality specifically in LTR …

Right Heart Recovery Post Lung Transplant With COVID‐19‐Related Acute Respiratory Distress Syndrome Open

Ambalavanan Arunachalam, Takahide Toyoda, Tanvi Nayak, Madeline Jankowski, Emily Cerier , et al. · 2024

Background: Right heart remodeling is noted in patients with severe COVID‐19‐associated acute respiratory distress syndrome (ARDS). There is limited information regarding right heart recovery following lung transplantation in this cohort. …

P2.19-02 [DREAM] Double Lung Transplant Registry Aimed for Lung-Limited Malignancies - A Prospective Registry Study for Medically Refractory Cancers Open

Young Kwang Chae, Liam Il‐Young Chung, Rade Tomic, A. Bharat · 2023

Primary graft dysfunction grade correlates with acute kidney injury stage after lung transplantation Open

Takahide Toyoda, Benjamin Louis Thomae, Viswajit Kandula, Adwaiy Manerikar, Yuriko Yagi , et al. · 2023

PGD grade was significantly correlated with AKI stage, and AKI stage was correlated with GFR categories of CKD.

Infectious Complications of Lung Transplant for Coronavirus Disease 2019–Associated Lung Injury: A Single-Center Case-Control Cohort Study Open

Rebecca Osborn, Maha Al‐Amri, Rade Tomic, Michael G. Ison · 2023

Background Lung transplantation is one of the only options for patients with severe coronavirus disease 2019 (COVID-19)–associated lung injury (CALI). Studies on patients who received a lung transplant for CALI have, to date, not looked at…

Neutropenia and Outcomes in Lung Transplant Recipients Open

Giovanni M. Perottino, Prashant Patel, A. O'Boye, Liuska Pesce, Rade Tomic , et al. · 2022

BMI Change and Outcomes in Lung Transplant Recipients Open

Melanie Sue Collins, A. O'Boye, A. Arunachalam, C. Myers, Giovanni M. Perottino , et al. · 2022

Provider Perspectives on and Access to Palliative Care for Patients With Interstitial Lung Disease Open

Rebecca A. Gersten, Bhavna Seth, L. Arellano, Jessica Shore, Lanier O’Hare , et al. · 2022

Delayed Mortality Among Solid Organ Transplant Recipients Hospitalized for COVID-19 Open

Madeleine R. Heldman, Olivia S. Kates, Kassem Safa, Camille N. Kotton, Ashrit Multani , et al. · 2022

Background Most studies of solid organ transplant (SOT) recipients with coronavirus disease 2019 (COVID-19) focus on outcomes within 1 month of illness onset. Delayed mortality in SOT recipients hospitalized for COVID-19 has not been fully…

Clinical Characteristics and Outcomes of Patients With COVID-19–Associated Acute Respiratory Distress Syndrome Who Underwent Lung Transplant Open

Chitaru Kurihara, Adwaiy Manerikar, Melissa Querrey, Christopher Felicelli, Anjana V. Yeldandi , et al. · 2022

In this single-center case series of 102 consecutive patients who underwent a lung transplant between January 21, 2020, and September 30, 2021, survival was 100% in the 30 patients who had COVID-19-associated ARDS as of November 15, 2021.

Bacterial Superinfection Pneumonia in Patients Mechanically Ventilated for COVID-19 Pneumonia Open

Chiagozie I. Pickens, Catherine A. Gao, Michael J. Cuttica, Sean B. Smith, Lorenzo L. Pesce , et al. · 2021

Rationale: Current guidelines recommend patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia receive empirical antibiotics for suspected bacterial superinfection on the basis of weak evidence. Rates o…

Lung donation following SARS-CoV-2 infection Open

Melissa Querrey, Chitaru Kurihara, Adwaiy Manerikar, Rafael Garza‐Castillon, Jeffrey Lysne , et al. · 2021

There have been over 177 million cases of COVID-19 worldwide, many of whom could be organ donors. Concomitantly, there is an anticipated increase in the need for donor lungs due to expanding indications. Given that the respiratory tract is…

COVID-19 in hospitalized lung and non-lung solid organ transplant recipients: A comparative analysis from a multicenter study Open

Madeleine R. Heldman, Olivia S. Kates, Kassem Safa, Camille N. Kotton, Sarah J. Georgia , et al. · 2021

Lung transplant recipients (LTR) with coronavirus disease 2019 (COVID-19) may have higher mortality than non-lung solid organ transplant recipients (SOTR), but direct comparisons are limited. Risk factors for mortality specifically in LTR …

Effect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis Open

Fernando J. Martínez, Eric Yow, Kevin R. Flaherty, Laurie D. Snyder, Michael T. Durheim , et al. · 2021

ClinicalTrials.gov Identifier: NCT02759120.

A Multicenter Prospective Registry Study of Lung Transplant Recipients Hospitalized with COVID-19 Open

Madeleine R. Heldman, Olivia S. Kates, Ashrit Multani, Julie M. Steinbrink, Also Lewis , et al. · 2021

Lung transplantation for patients with severe COVID-19 Open

Ankit Bharat, Melissa Querrey, Nikolay S. Markov, Samuel S. Kim, Chitaru Kurihara , et al. · 2020

Some patients with severe COVID-19 develop end-stage pulmonary fibrosis for which lung transplantation may be the only treatment.

Comparing Nasopharyngeal and BAL SARS-CoV-2 Assays in Respiratory Failure Open

Catherine A. Gao, Michael J. Cuttica, Elizabeth S. Malsin, A. Christine Argento, Richard G. Wunderink , et al. · 2020

Lung transplantation for pulmonary fibrosis secondary to severe COVID-19 Open

Ankit Bharat, Melissa Querrey, Nikolay S. Markov, Samuel S. Kim, Chitaru Kurihara , et al. · 2020

Lung transplantation can potentially be a life-saving treatment for patients with non-resolving COVID-19 acute respiratory distress syndrome. Concerns limiting transplant include recurrence of SARS-CoV-2 infection in the allograft, technic…

Impact of Screening and Treatment of<i>Ureaplasma</i>species on Hyperammonemia Syndrome in Lung Transplant Recipients: A Single Center Experience Open

Scott C. Roberts, Ankit Bharat, Chitaru Kurihara, Rade Tomic, Michael G. Ison · 2020

Background Infection with Ureaplasma species (spp) has been linked to fatal hyperammonemia syndrome (HS) in lung transplant recipients. We sought to characterize the epidemiology of Ureaplasma spp in candidates and donors and describe outc…

International Society for Heart and Lung Transplantation consensus statement for the standardization of bronchoalveolar lavage in lung transplantation Open

Tereza Martinu, Angela Koutsokera, Christian Benden, Edward Cantu, Daniel C. Chambers , et al. · 2020

Feasibility of Venovenous Extracorporeal Membrane Oxygenation Without Systemic Anticoagulation Open

Chitaru Kurihara, James M. Walter, Azad Karim, Sanket Thakkar, Mark Saine , et al. · 2020

Clinical relevance of lung-restricted antibodies in lung transplantation Open

Mahzad Akbarpour, Qiang Wu, Xianpeng Liu, Haiying Sun, Emilia Lecuona , et al. · 2019

Acute exacerbation of interstitial lung disease after procedures Open

William H. Amundson, Emilian Racila, Tadashi Allen, H. Erhan Dinçer, Rade Tomic , et al. · 2019

Patients' perceptions and patient-reported outcomes in progressive-fibrosing interstitial lung diseases Open

Jeffrey J. Swigris, Kevin K. Brown, Rayid Abdulqawi, Ketan Buch, Daniel F. Dilling , et al. · 2018

The effects of interstitial lung disease (ILD) create a significant burden on patients, unsettling almost every domain of their lives, disrupting their physical and emotional well-being and impairing their quality of life (QoL). Because ma…

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